Chronic lymphocytic leukaemia: open trials in Israel

10 open trials have a site in Israel. Registry data; only the trial team decides who can take part.

NCT05947851
A Study of Nemtabrutinib Plus Venetoclax vs Venetoclax + Rituximab (VR) in Second-line (2L) + Relapsed/Refractory (R/R) Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) (MK-1026-010/BELLWAVE-010).
Trial Treatment · Phase 3 · Merck Sharp & Dohme LLC
Rambam Health Care Campus (Site 2801), Haifa · Hadassah Medical Center-Hemato-Oncology (Site 2812), Jerusalem · Sheba Medical Center-Hemato Oncology (Site 2809), Ramat Gan · Sourasky Medical Center (Site 2811), Tel Aviv
Registry updated 2026-11-06
NCT06788509
A Rollover Study for Continued Study Treatment and Ongoing Safety Monitoring
Trial Treatment · Phase 1 · Janssen Research & Development, LLC
Carmel Medical Center, Haifa · Rambam Med.Center - Hematology Institute, Haifa · Rambam Medical Center, Haifa · Hadassah University Hospita Ein Kerem, Jerusalem · Tel-Aviv Sourasky Medical Center, Tel Aviv
Registry updated 2026-11-04
NCT07218341
A Study of Pirtobrutinib (LY3527727) in Participants With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Trial Treatment · Phase 4 · Eli Lilly and Company
Tel-Aviv Sourasky Medical Center, Tel Aviv
Registry updated 2026-11-04
NCT07709000
A Clinical Trial of MK-1045 in People With B-cell Cancer (MK-1045-006)
Trial Treatment · Phase 2 · Merck Sharp & Dohme LLC
Rambam Health Care Campus (Site 0803), Haifa · Shaare Zedek Medical Center (Site 0801), Jerusalem · Haddasah Medical Center (Site 0800), Jerusalem · Sheba Medical Center (Site 0802), Ramat Gan · Sourasky Medical Center (Site 0804), Tel Aviv
Registry updated 2026-11-04
NCT04728893
Efficacy and Safety of Nemtabrutinib (MK-1026) in Participants With Hematologic Malignancies (MK-1026-003)
Trial Treatment · Phase 2 · Merck Sharp & Dohme LLC
Ha Emek Medical Center (Site 1305), Afula · Soroka Medical Center (Site 1307), Beersheba · Rambam Medical Center (Site 1301), Haifa · Hadassah Ein Karem Jerusalem (Site 1300), Jerusalem · Chaim Sheba Medical Center (Site 1302), Ramat Gan · Kaplan Medical Center (Site 1304), Rehovot · Sourasky Medical Center (Site 1303), Tel Aviv
Registry updated 2026-10-27
NCT06136559
A Study of Nemtabrutinib (MK-1026) Versus Comparator (Investigator's Choice of Ibrutinib or Acalabrutinib) in First Line (1L) Chronic Lymphocytic Leukemia (CLL)/ Small Lymphocytic Lymphoma (SLL) (MK-1026-011/BELLWAVE-011)
Trial Treatment · Phase 3 · Merck Sharp & Dohme LLC
Bnai Zion Medical Center (Site 1505), Haifa · Rambam Health Care Campus-Hematology and Bone Marrow Transplantation (Site 1503), Haifa · Hadassah Medical Center-Hemato-Oncology (Site 1500), Jerusalem · Galilee Medical Center (Site 1507), Nahariya · Rabin Medical Center (Site 1504), Petah Tikva · Sheba Medical Center-Hemato Oncology (Site 1501), Ramat Gan · Yitzhak Shamir Medical Center. (Site 1506), Tsrifin
Registry updated 2026-10-13
NCT06973187
A Study to Evaluate the Safety and Efficacy of Tacabrutideg (BGB-16673) Compared to Pirtobrutinib in Adults With Relapsed/Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Trial Treatment · Phase 3 · BeOne Medicines
Bnai Zion Medical Center, Haifa · Hadassah University Hospital - Ein Kerem, Jerusalem · Shaare Zedek Medical Center, Jerusalem · Meir Medical Center, KfarSava · Rabin Medical Center, Petah Tikva · Sheba medical center, Ramat Gan · Sourasky Tel Aviv Medical Center, Tel Aviv
Registry updated 2026-09-28
NCT05254743
A Study of Pirtobrutinib (LOXO-305) Versus Ibrutinib in Participants With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)
Trial Treatment · Phase 3 · Loxo Oncology, Inc.
Hadassah medical Center, Jerusalem · Tel-Aviv Sourasky Medical Center, Tel Aviv
Registry updated 2026-08-17
NCT06104566
Global Trial in APG2575 for Patients With CLL/SLL
Trial Treatment · Phase 3 · Ascentage Pharma Group Inc.
Haifa · Jerusalem · Kfar Saba · Tel Aviv
Registry updated 2026-06-18
NCT04895436
Study to Assess Change in Disease Activity and Adverse Events of Oral Venetoclax With Intravenous (IV) Obinutuzumab in Adult Participants With Recurring Chronic Lymphocytic Leukemia (CLL)
Trial Treatment · Phase 2 · AbbVie
Hadassah /ID# 245059, Jerusalem · Rabin Medical Center. /ID# 243220, Petah Tikva · The Chaim Sheba Medical Center /ID# 243219, Ramat Gan · Tel Aviv Sourasky Medical Center /ID# 243218, Tel Aviv
Registry updated 2026-02-09

All Chronic lymphocytic leukaemia trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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