Colorectal cancer: open trials in Belgium

77 open trials have a site in Belgium. Registry data; only the trial team decides who can take part.

NCT07923682
Outcomes of Knife-Assisted Full-Thickness Resection for Rectal Lesions: A Multicenter Study
Research · University Hospital, Ghent
University Hospital Ghent, Ghent
Registry updated 2026-11-06
NCT06324357
Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread
Trial Treatment · Phase 1/2 · Boehringer Ingelheim
Cliniques universitaires Saint-Luc, Brussels · Universitair Ziekenhuis Antwerpen, Edegem · UZ Leuven, Leuven · Hôpital Vivalia De Libramont, Libramont-Chevigny · Centre Hospitalier Universitaire de Liège, Liège · CHU UCL Namur, Namur
Registry updated 2026-11-05
NCT07228832
Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer
Trial Treatment · Phase 3 · Summit Therapeutics
Brussels · Ghent · Haine-Saint-Paul · Kortrijk
Registry updated 2026-11-05
NCT07549412
A Study of Precemtabart Tocentecan With or Without Bevacizumab Compared to Trifluridine/Tipiracil Plus Bevacizumab in Participants With Previously Treated Metastatic Colorectal Cancer (PROCEADE-CRC-03)
Trial Treatment · Phase 3 · EMD Serono Research & Development Institute, Inc.
Grand Hopital de Charleroi, Charleroi · Universitair Ziekenhuis Antwerpen, Edegem · UZ Leuven, Leuven · Cliniques Universitaires Saint-Luc, Sint-Lambrechts-Woluwe
Registry updated 2026-11-05
NCT05379595
A Study of Amivantamab Monotherapy and in Addition to Standard-of-Care Chemotherapy in Participants With Advanced or Metastatic Colorectal Cancer
Trial Treatment · Phase 1/2 · Janssen Research & Development, LLC
Institut Jules Bordet, Anderlecht · Antwerp University Hospital, Edegem · UZ Leuven, Leuven · Cliniques Universitaires Saint-Luc, Sint-Lambrechts-Woluwe
Registry updated 2026-11-03
NCT05856981
Phase 1 Study Evaluating the Safety and PK of ADU-1805 in Advanced Solid Tumors
Trial Treatment · Phase 1 · Sairopa B.V.
Grand Hopital de Charleroi (GHdC) - Hopital Notre Dame, Charleroi
Registry updated 2026-11-03
NCT06662786
A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer
Trial Treatment · Phase 3 · Janssen Research & Development, LLC
Institut Jules Bordet, Anderlecht · Antwerp University Hospital, Edegem · Az Maria Middelares Gent, Gent · Algemeen Ziekenhuis Groeninge, Kortrijk · Chu Helora, La Louvière · UZ Leuven, Leuven · Centre Hospitalier Universitaire de Liège, Liège
Registry updated 2026-11-03
NCT06750094
A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy
Trial Treatment · Phase 3 · Janssen Research & Development, LLC
Institut Jules Bordet, Anderlecht · Antwerp University Hospital, Edegem · Algemeen Ziekenhuis Groeninge, Kortrijk · Chu Helora, La Louvière · UZ Leuven, Leuven · Centre Hospitalier Universitaire de Liège, Liège
Registry updated 2026-11-03
NCT03526835
A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors
Trial Treatment · Phase 1/2 · Genmab
Institut Jules Bordet, Anderlecht · Universitair Ziekenhuis Gent, Gent · Centre Hospitalier Universitaire Dinant Godinne Sainte-Elisabeth-UCL-Namur, Namur · Cliniques Universitaires Saint-Luc, Sint-Lambrechts-Woluwe
Registry updated 2026-11-02
NCT07262619
EIK1005-002: A Clinical Research Study Evaluating EIK1005, a Werner Helicase Inhibitor, as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors Including Microsatellite Instability High (MSI-H) Tumors
Trial Treatment · Phase 1/2 · Eikon Therapeutics
Centre Hospitalier Universitaire Brugmann - Victor Horta, Brussels
Registry updated 2026-10-30
NCT07284849
A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer
Trial Treatment · Phase 3 · Incyte Corporation
Universitair Ziekenhuis Antwerpen, Edegem · Universiteit Gent, Gent · UZ Brussel, Jette · UZ Leuven, Leuven · Cliniques Universitaires Saint-Luc, Sint-Lambrechts-Woluwe · Centre Hospitalier Universitaire Dinant Godinne Sainte-Elisabeth-UCL-Namur, Yvoir
Registry updated 2026-10-30
NCT07808151
Neoadjuvant Pembrolizumab and Porustobart in Resectable pMMR/MSS Colon Cancer
Trial Treatment · Phase 2 · Solstice Oncology, Inc.
Anderlecht · Bonheiden · Ghent · Leuven · Liège · Ostend · Woluwe-Saint-Lambert
Registry updated 2026-10-27
2026-525883-17-00
Study of Petosemtamab Plus Chemotherapy Versus Cetuximab Plus Chemotherapy in RAS and BRAF Wild-type, Unresectable or Metastatic, Left-sided Colorectal Cancer.
Trial Treatment · Phase 3 · Genmab A/S
Institut Jules Bordet, Anderlecht · Imelda, Bonheiden · Grand Hopital de Charleroi, Charleroi · Chu Helora, La Louvière · Vivalia, Libramont-Chevigny · Centre Hospitalier Universitaire Dinant Godinne Sainte-Elisabeth-UCL-Namur, Namur · Algemeen Ziekenhuis Delta, Roeselare · Cliniques Universitaires Saint-Luc, Sint-Lambrechts-Woluwe · Centre Hospitalier Universitaire Dinant Godinne Sainte-Elisabeth-UCL-Namur, Yvoir
Registry updated 2026-10-26
NCT06330064
A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02)
Trial Treatment · Phase 1/2 · Daiichi Sankyo
Grand Hopital de Charleroi, Charleroi · Universitair Ziekenhuis Gent, Gent · UZ Leuven, Leuven · Centre Hospitalier Universitaire de Liège, Liège · Cliniques Universitaires Saint-Luc, Sint-Lambrechts-Woluwe
Registry updated 2026-10-26
NCT07474025
Biopsy-Resection Agreement of Peritoneal Histopathological Growth Patterns in Colorectal Peritoneal Metastases: A Prospective Observational Pilot Study
Research · Jules Bordet Institute
Institut Jules Bordet, Brussels · Hub Bordet, Brussels
Registry updated 2026-10-26
NCT07221357
A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Bevacizumab in Combination With Chemotherapy in Participants With Previously Untreated, Unresectable, or Metastatic Colorectal Cancer
Trial Treatment · Phase 2/3 · Bristol-Myers Squibb
Imelda, Bonheiden · University Of Antwerp, Edegem · UZ Leuven, Leuven · Algemeen Ziekenhuis Delta, Roeselare · Cliniques Universitaires Saint-Luc, Sint-Lambrechts-Woluwe
Registry updated 2026-10-23
NCT06004245
A Study to Evaluate the Safety, Pharmacokinetics, and Anti-Tumor Activity of VVD-133214 as Monotherapy and in Combination in Participants With Advanced Solid Tumors
Trial Treatment · Phase 1 · Vividion Therapeutics, Inc.
Cliniques universitaires de Saint Luc, Brussels · UZ Leuven Gasthuisberg, Ghent · UZ Gent, Ghent
Registry updated 2026-10-21
NCT07811193
A Study to Evaluate the Efficacy of VVD-133214 in Combination With Pembrolizumab Compared With Pembrolizumab Alone in Participants With Advanced Cancer of the Colon or Rectum
Trial Treatment · Phase 2 · Vividion Therapeutics, Inc.
Institut Jules Bordet - Clinique D'Oncology, Brussels · UZ Gent - Digestive Oncology, Ghent · CHU Helora - Hopital de La Louvière - Site Jolimont - Oncology department, La Louvière · UZ Leuven - Digestive oncology, Leuven · AZ Delta - Digestive oncology, Roeselare
Registry updated 2026-10-21
NCT06934538
First-in-human Trial of STC-1010, an Immunotherapy, in Patients With Unresectable Locally Advanced or Metastatic Colorectal Cancer
Trial Treatment · Phase 1/2 · Brenus Pharma
Institut Jules Bordet, Brussels
Registry updated 2026-10-20
NCT06885034
A Study to Test the Safety and Effectiveness of GSK5764227, Alone or With Other Treatments, in Participants With Advanced Gastrointestinal Cancers That Cannot be Surgically Removed (EMBOLD PanGI-201)
Trial Treatment · Phase 1/2 · GlaxoSmithKline
Bonheiden · Brussels · Leuven · Roeselare
Registry updated 2026-10-19
NCT07525206
A Study to Access Intravenous (IV) Telisotuzumab Adizutecan in Combination With IV Bevacizumab Compared to Standard of Care IV Bevacizumabin Combination With Oral Trifluridine and Tipiracil in Adult Participants With Refractory Metastatic Colorectal Cancer
Trial Treatment · Phase 3 · AbbVie
Institut Jules Bordet, Anderlecht · Imelda, Bonheiden · Grand Hopital de Charleroi, Charleroi · Universitair Ziekenhuis Antwerpen, Edegem · Az Maria Middelares Gent, Gent · UZ Brussel, Jette · UZ Leuven, Leuven · Algemeen Ziekenhuis Delta, Roeselare · Cliniques Universitaires Saint-Luc, Sint-Lambrechts-Woluwe · Centre Hospitalier Universitaire Dinant Godinne Sainte-Elisabeth-UCL-Namur, Yvoir
Registry updated 2026-10-19
2025-521587-35-00
A Randomized, Active-Controlled, Double-blind, Multicenter, Phase 3 Clinical Study of Ivonescimab in Combination with FOLFOX versus Bevacizumab in Combination with FOLFOX for the First-line Treatment of Metastatic Colorectal Cancer (HARMONi-GI3)
Trial Treatment · Phase 3 · Summit Therapeutics Inc.
Institut Jules Bordet, Anderlecht · Universitair Ziekenhuis Gent, Gent · Algemeen Ziekenhuis Groeninge, Kortrijk · Chu Helora, La Louvière · Cliniques Universitaires Saint-Luc, Sint-Lambrechts-Woluwe
Registry updated 2026-10-16
NCT07023289
A Study to Assess Adverse Events and Change in Disease Activity in Adult Participants Receiving Intravenously Infused Telisotuzumab Adizutecan Alone or With Standard of Care in Participants With Post Adjuvant Circulating Tumor DNA Positive Colorectal Cancer and No Radiographic Evidence of Disease
Trial Treatment · Phase 2 · AbbVie
UZ Leuven, Leuven · Centre Hospitalier Universitaire de Liège, Liège · Cliniques Universitaires Saint-Luc, Sint-Lambrechts-Woluwe
Registry updated 2026-10-09
NCT07222800
Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer
Trial Treatment · Phase 3 · Pfizer
Grand Hopital de Charleroi, Charleroi · AZ Sint-Lucas & Volkskliniek, Gent · UZ Leuven, Leuven · Algemeen Ziekenhuis Delta, Roeselare
Registry updated 2026-10-08
NCT07535112
A Study to Learn More About How Safe BAY 3771249 is and How Well it Works in People With Advanced or Metastatic Colorectal Cancer That Has a KRAS G12D Mutation
Trial Treatment · Phase 1 · Bayer
Ghent University Hospital | Drug Research Unit Department, Ghent
Registry updated 2026-10-05

All Colorectal cancer trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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