Colorectal cancer trials in China

In China 616 Also abroad 1941

616 trials · From ClinicalTrials.gov, checked 15 November 2026. Ask the study team whether a trial fits you.

Phase 2Taking people
JS212 Combination Therapies in Metastatic Colorectal Cancer
Where
Shanghai
Age
18 years to 75 years
People
80
Run by
Shanghai Junshi Bioscience Co., Ltd.
See details and how to joinNCT07503756
No phaseTaking people
Rectal Cancer Neoadjuvant Therapy-Real World Study
Where
Beijing
Age
18 years and over
People
869
Run by
Beijing Friendship Hospital
See details and how to joinNCT07566559
Phase 1/2Taking people
A Phase Ib/II Trial of HS-20110 Combination Therapies in Advanced Colorectal Cancer Patients.
Where
Guangzhou
Age
18 years and over
People
502
Run by
Hansoh BioMedical R&D Company
See details and how to joinNCT07283367
Phase 1/2Taking people
Low Rectal Cancer Treated With Total Neoadjuvant Therapy Plus Concurrent Tislelizumab Immunotherapy
Where
Shanghai
Age
18 years to 75 years
People
50
Run by
Fudan University
See details and how to joinNCT07561060
Phase 2Taking people
A Randomized Controlled Trial of Plasma ctDNA Methylation-Guided Adjuvant Chemotherapy Decision-Making in High-Risk Stage III (T4N+ or T1-3N2) Colorectal Cancer
Where
Shanghai
Age
18 years to 80 years
People
100
Run by
Fudan University
See details and how to joinNCT07562490
Phase 2Taking people
Randomized Trial of Plasma ctDNA Methylation-Guided Adjuvant Therapy in T4N0 and Low-Risk Stage III Colorectal Cancer
Where
Shanghai
Age
18 years to 80 years
People
340
Run by
Fudan University
See details and how to joinNCT07562503
Phase 2Taking people
Randomized Controlled Study of Plasma ctDNA Methylation-Guided Adjuvant Chemotherapy in Stage I/Low-Risk Stage II Colorectal Cancer
Where
Shanghai
Age
18 years to 80 years
People
80
Run by
Fudan University
See details and how to joinNCT07562659
Phase 2Taking people
Randomized Study of Plasma ctDNA Methylation to Guide Adjuvant Chemotherapy Decisions in High-Risk T3N0 Colorectal Cancer
Where
Shanghai
Age
18 years to 80 years
People
340
Run by
Fudan University
See details and how to joinNCT07562711
Phase 3Taking people
Neoadjuvant CAPOX With or Without Pucotenlimab Plus Selective Radiotherapy for Locally Advanced Rectal Cancer
Where
Guangzhou
Age
18 years to 75 years
People
556
Run by
Sun Yat-sen University
See details and how to joinNCT07528209
Phase 2Taking people
New Second-Line Combo Therapy for MSS Metastatic Colorectal Cancer
Where
Changchun
Age
18 years to 75 years
People
30
Run by
The First Hospital of Jilin University
See details and how to joinNCT07559760
Phase 2Taking people
Fruquintinib Combined With Sintilimab ± Radiotherapy for Third-line Treatment of Colorectal Cancer With Liver Metastases
Where
Jinan
Age
18 years to 75 years
People
62
Run by
Shandong Cancer Hospital and Institute
See details and how to joinNCT06356584
Early phase 1Enrolling by invitation
MRD-positive Colorectal Cancer Patients Combined With Personalized Immune Regulation Diagnosis
Where
Wenzhou
Age
18 years to 80 years
People
10
Run by
Second Affiliated Hospital of Wenzhou Medical University
See details and how to joinNCT06434376
Phase 2Taking people
Radiotherapy Plus Iparomlimab and Tuvonralimab (QL1706), Regorafenib, and CAPOX as Neoadjuvant Therapy for pMMR/MSS LARC.
Where
Guangzhou
Age
18 years to 75 years
People
88
Run by
Sun Yat-sen University
See details and how to joinNCT06911684
Phase 2Not yet taking people in China
Oncolytic Virus (H101) + SBRT + Chemotherapy + Targeted Therapy + Immunotherapy for Unresectable CRLM
Where
Guangzhou
Age
18 years to 75 years
People
114
Run by
Jun Huang
See details and how to joinNCT07381309
No phaseTaking people
Watch and Wait in PD-1 Monoclonal Antibody Treated dMMR/MSI-H Distal Rectal Cancer
Where
Guangzhou
Age
18 years to 80 years
People
47
Run by
Sixth Affiliated Hospital, Sun Yat-sen University
See details and how to joinNCT04643041
Phase 2Taking people
Safety and Efficacy of PD-1 ± mFOLFOX6 Neoadjuvant Therapy in Local Advanced sMPCC
Where
Guangzhou
Age
18 years to 80 years
People
17
Run by
Sixth Affiliated Hospital, Sun Yat-sen University
See details and how to joinNCT06002789
Phase 1Not yet taking people in China
LDRT Sequential NIPS Immunochemotherapy for Peritoneal Metastasis of Gastric and Colorectal Cancer
Where
Chongqing
Age
18 years to 75 years
People
9
Run by
Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
See details and how to joinNCT07453875
No phaseTaking people
Sub-topic Four: Clinical Translation of Original Radioactive Drugs for Precision Diagnosis and Treatment of Gastrointestinal Tumors -Clinical Application Value of PET Imaging Targeting LRRC15 in Malignant Tumors
Where
Wuhan
Age
18 years and over
People
26
Run by
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
See details and how to joinNCT07552467
Phase 2Taking people
Node-sparing Radiotherapy Combined With Total Neoadjuvant CAPOX and Sintilimab for MSS Middle and Low Rectal Cancer
Where
Jinhua
Age
18 years to 75 years
People
37
Run by
Jinhua Central Hospital
See details and how to joinNCT06204094
Phase 1/2Taking people
A Study of TSN1611 Treating Patients With Advanced Solid Tumors Harboring KRAS G12D Mutation
Where
Beijing, Changsha, Chengdu, Guangzhou, Hangzhou, Hefei, Linyi, Nanchang, Shanghai, Taizhou, Wuhan
Age
18 years to 75 years
People
440 worldwide
Run by
Tyligand Pharmaceuticals (Suzhou) Limited
See details and how to joinNCT06385925
No phaseTaking people
Predicting the Efficacy of Neoadjuvant Therapy in Patients With Locally Advanced Rectal Cancer Using an AI Platform Based on Multi-parametric MRI
Where
Guangzhou, Zhuhai
Age
18 years and over
People
1,700
Run by
Sixth Affiliated Hospital, Sun Yat-sen University
See details and how to joinNCT05523245
No phaseTaking people
A Study on the Accurate Evaluation of Pseudoprogression of Rectal Cancer Immunotherapy Based on Multitemporal and Multiparameter MRI
Where
Guangzhou, Maoming
People
300
Run by
Peiyi Xie
See details and how to joinNCT07381322
Phase 2Not yet taking people in China
Improvement Effect of Dexamethasone Enema for Acute Radiation-induced Rectal Injury
Where
Guangzhou
Age
18 years to 75 years
People
40
Run by
Sixth Affiliated Hospital, Sun Yat-sen University
See details and how to joinNCT07548736
Phase 3Taking people
Neoadjuvant/Adjuvant AK104 in Microsatellite Instability-high or Mismatch Repair-deficient, Resectable Colon Cancer
Where
Guangzhou
Age
18 years to 75 years
People
386
Run by
Akeso
See details and how to joinNCT07412613
Phase 2Not yet taking people in China
A Prospective, Multicenter, Single-Arm Phase II Exploratory Study of Serplulimab Combined With Oncolytic Virus H101, Short-Course Radiotherapy, and XELOX Chemotherapy as Total Neoadjuvant Treatment for Locally Advanced (cT1-3N0M0) Rectal Cancer
Where
Chongqing
Age
18 years to 80 years
People
20
Run by
Chongqing University Cancer Hospital
See details and how to joinNCT07543848