Colorectal cancer: open trials in Puerto Rico

20 open trials have a site in Puerto Rico. Registry data; only the trial team decides who can take part.

NCT07018869
Evaluating Whether an Educational Website Called Current Together After Cancer (CTAC) Improves Follow-up Care for Colorectal Cancer Survivors
Trial Treatment · Phase 3 · SWOG Cancer Research Network
Puerto Rico Hematology Oncology Group, Bayamón · Cancer Center-Metro Medical Center Bayamon, Bayamón · Doctors Cancer Center, Manati · Centro Comprensivo de Cancer de UPR, San Juan · San Juan Community Oncology Group, San Juan · San Juan City Hospital, San Juan · PROncology, San Juan
Registry updated 2026-11-06
NCT06824064
Evaluation of RBS2418 in Patients With Advanced, Metastatic, and Progressive Colorectal Cancer
Trial Treatment · Phase 2 · Riboscience, LLC.
Pan Oncology, San Juan
Registry updated 2026-11-05
NCT07228832
Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer
Trial Treatment · Phase 3 · Summit Therapeutics
Rio Piedras
Registry updated 2026-11-05
NCT05080673
Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps
Trial Treatment · NRG Oncology
Puerto Rico Hematology Oncology Group, Bayamón · Cancer Center-Metro Medical Center Bayamon, Bayamón · HIMA San Pablo Oncologic Hospital, Caguas · Pan American Center for Oncology Trials LLC - Dorado, Dorado · Pan American Center for Oncology Trials LLC - Manati, Manati · Doctors Cancer Center, Manati · Instituto Oncologia Moderna Ponce, Ponce · San Juan Veterans Affairs Medical Center, San Juan · Pan American Center for Oncology Trials LLC, San Juan · Primary Care Physician Group, San Juan · Centro Comprensivo de Cancer de UPR, San Juan · Pan American Center for Oncology Trials LLC - Ciudadela, San Juan · San Juan Community Oncology Group, San Juan · PROncology, San Juan · San Juan City Hospital, San Juan
Registry updated 2026-11-04
NCT05174169
Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease
Trial Treatment · Phase 2/3 · NRG Oncology
Pan American Center for Oncology Trials LLC - Cayey, Cayey · Pan American Center for Oncology Trials LLC - Dorado, Dorado · Doctors Cancer Center, Manati · PROncology, San Juan · Centro Comprensivo de Cancer de UPR, San Juan · San Juan City Hospital, San Juan · Pan American Center for Oncology Trials LLC - Ciudadela, San Juan · Pan American Center for Oncology Trials LLC, San Juan
Registry updated 2026-11-04
NCT06418204
Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics
Research · Wake Forest University Health Sciences
Doctors Cancer Center, Manati · Centro Comprensivo de Cancer de UPR, San Juan · PROncology, San Juan
Registry updated 2026-11-04
NCT07283939
Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays
Trial Treatment · Alliance for Clinical Trials in Oncology
Puerto Rico Hematology Oncology Group, Bayamón · Cancer Center-Metro Medical Center Bayamon, Bayamón · Doctors Cancer Center, Manati · San Juan City Hospital, San Juan · PROncology, San Juan · San Juan Community Oncology Group, San Juan · Centro Comprensivo de Cancer de UPR, San Juan
Registry updated 2026-11-04
NCT05379595
A Study of Amivantamab Monotherapy and in Addition to Standard-of-Care Chemotherapy in Participants With Advanced or Metastatic Colorectal Cancer
Trial Treatment · Phase 1/2 · Janssen Research & Development, LLC
Ad-Vance Medical Research, Ponce · Pan American Center for Oncology Trials LLC, Rio Piedras
Registry updated 2026-11-03
NCT06662786
A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer
Trial Treatment · Phase 3 · Janssen Research & Development, LLC
Pan American Center for Oncology Trials LLC, Barrio Monacillos
Registry updated 2026-11-03
NCT06750094
A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy
Trial Treatment · Phase 3 · Janssen Research & Development, LLC
Pan American Center for Oncology Trials LLC, San Juan
Registry updated 2026-11-03
NCT07143487
Family Communications After Genetic Testing
Trial Treatment · Alliance for Clinical Trials in Oncology
Puerto Rico Hematology Oncology Group, Bayamón · Cancer Center-Metro Medical Center Bayamon, Bayamón · Doctors Cancer Center, Manati · Centro Comprensivo de Cancer de UPR, San Juan · San Juan Community Oncology Group, San Juan · San Juan City Hospital, San Juan · PROncology, San Juan
Registry updated 2026-11-03
NCT07702032
Study of Petosemtamab Plus Chemotherapy Versus Cetuximab Plus Chemotherapy in RAS and BRAF Wild-type, Unresectable or Metastatic, Left-sided Colorectal Cancer (LiGeR-CRC1)
Trial Treatment · Phase 3 · Genmab
PanOncology, Manati
Registry updated 2026-11-03
NCT07775287
Study of Petosemtamab Plus Chemotherapy Versus Cetuximab or Bevacizumab Plus Chemotherapy in RAS and BRAF Wild Type, Recurrent, Unresectable or Metastatic Colorectal Cancer (LiGeR-CRC2)
Trial Treatment · Phase 3 · Genmab
PanOncology, Manati
Registry updated 2026-11-03
NCT07284849
A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer
Trial Treatment · Phase 3 · Incyte Corporation
Pan American Center for Oncology Trials, LLC- Dorado Office, Dorado
Registry updated 2026-10-30
NCT06820463
A Study to Evaluate the Adverse Events, and Efficacy of Intravenous (IV) of Telisotuzumab Adizutecan in Combination With IV Oxaliplatin, Fluorouracil, Folinic Acid/Leucovorin, Bevacizumab, Panitumumab in Adult Participants With Metastatic Colorectal Cancer
Trial Treatment · Phase 2 · AbbVie
Pan American Center for Oncology Trials - Rio Piedras /ID# 268809, Rio Piedras · Puerto Rico Medical Research Center /ID# 268825, San Juan
Registry updated 2026-10-27
NCT07222800
Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer
Trial Treatment · Phase 3 · Pfizer
Pan American Center for Oncology Trials - Mayaguez, Mayagüez · Pan American Center for Oncology Trials LLC, Rio Piedras · Pan American Center for Oncology Trials LLC, San Juan · Pan American Center for Oncology Trials, LLC - Centro Europa Office, San Juan
Registry updated 2026-10-08
NCT06128551
Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors
Trial Treatment · Phase 1/2 · Revolution Medicines, Inc.
Pan American Center for Oncology Trials, San Juan
Registry updated 2026-09-22
NCT06252649
Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Participants With Metastatic Colorectal Cancer With KRAS p.G12C Mutation
Trial Treatment · Phase 3 · Amgen
Pan American Center for Oncology Trials LLC, Rio Piedras
Registry updated 2026-09-03
NCT06562543
A Trial to Evaluate the Safety and Activity of Fruquintinib in Minority Populations With Advanced, Previously Treated Colorectal Cancer
Trial Treatment · Phase 4 · Takeda
Fundacion de Investigacion de Diego (FDI Clinical Research), San Juan
Registry updated 2026-07-07
NCT03452774
SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
Research · Massive Bio, Inc.
San Juan
Registry updated 2025-10-28

All Colorectal cancer trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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