Colorectal cancer: open trials in Singapore

14 open trials have a site in Singapore. Registry data; only the trial team decides who can take part.

NCT06997497
A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People With Colorectal Cancer (MK-1084-012/KANDLELIT-012)
Trial Treatment · Phase 3 · Merck Sharp & Dohme LLC
National Cancer Centre Singapore (Site 0650), Singapore
Registry updated 2026-11-04
NCT07262619
EIK1005-002: A Clinical Research Study Evaluating EIK1005, a Werner Helicase Inhibitor, as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors Including Microsatellite Instability High (MSI-H) Tumors
Trial Treatment · Phase 1/2 · Eikon Therapeutics
National Cancer Centre Singapore NCCS, Singapore · National University Hospital (NUH), Singapore
Registry updated 2026-10-30
NCT07221357
A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Bevacizumab in Combination With Chemotherapy in Participants With Previously Untreated, Unresectable, or Metastatic Colorectal Cancer
Trial Treatment · Phase 2/3 · Bristol-Myers Squibb
Tan Tock Seng Hospital, Singapore · Curie Oncology (Farrer), Singapore · National University Hospital, Singapore · National Cancer Centre Singapore, Singapore
Registry updated 2026-10-23
NCT07811193
A Study to Evaluate the Efficacy of VVD-133214 in Combination With Pembrolizumab Compared With Pembrolizumab Alone in Participants With Advanced Cancer of the Colon or Rectum
Trial Treatment · Phase 2 · Vividion Therapeutics, Inc.
Curie Oncology (Farrer), Singapore · National Cancer Center Singapore - Oncology Department, Singapore · National University Hospital - National University Cancer Institute (NCIS), Singapore · OncoCare Cancer Centre | Gleneagles Medical Centre, Singapore
Registry updated 2026-10-21
NCT07261631
Phase I Study of [177Lu]Lu-DFC413 in Patients With Solid Tumors
Trial Treatment · Phase 1 · Novartis Pharmaceuticals
Singapore
Registry updated 2026-10-09
NCT07535112
A Study to Learn More About How Safe BAY 3771249 is and How Well it Works in People With Advanced or Metastatic Colorectal Cancer That Has a KRAS G12D Mutation
Trial Treatment · Phase 1 · Bayer
National Cancer Center Singapore - Oncology Department, Singapore · National University Hospital Medical Centre, Singapore
Registry updated 2026-10-05
NCT04585750
The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
Trial Treatment · Phase 1/2 · PMV Pharmaceuticals, Inc
National University Hospital, Kent Ridge · National Cancer Center of Singapore, Singapore
Registry updated 2026-10-02
NCT07852793
Mailed FIT-Based Outreach Interventions
Trial Treatment · National Cancer Centre, Singapore
Sengkang General Hospital, Singapore · Singapore General Hospital, Singapore · National Cancer Center Singapore, Singapore · SingHealth Polyclinic, Singapore · Changi General Hospital, Singapore
Registry updated 2026-10-01
NCT04912765
Neoantigen Dendritic Cell Vaccine and Nivolumab in HCC and Liver Metastases From CRC
Trial Treatment · Phase 2 · National Cancer Centre, Singapore
National Cancer Center Singapore, Singapore
Registry updated 2026-07-31
NCT07169734
A Study to Investigate ALE.P03 as Monotherapy in Adult Patients With Selected Advanced or Metastatic CLDN1+ Solid Tumors
Trial Treatment · Phase 1/2 · Alentis Therapeutics AG
National Cancer Centre Singapore NCCS, Singapore · National University Hospital (NUH) - Medical Oncology, Singapore
Registry updated 2026-07-02
NCT07615036
AP-NOSES: A Prospective Multicentre Registry of Natural Orifice Specimen Extraction in Minimally Invasive Colorectal Surgery
Research · Singapore General Hospital
Singapore General Hospital, Singapore
Registry updated 2026-05-29
NCT03093116
A Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 Rearrangements
Trial Treatment · Phase 1/2 · Turning Point Therapeutics, Inc.
National University Hospital, Singapore · National Cancer Center Singapore, Singapore
Registry updated 2026-05-27
NCT06846268
Neoadjuvant ADG126 and Pembrolizumab in Locally Advanced Colorectal Cancer
Trial Treatment · Phase 2 · National University Hospital, Singapore
National University Hospital, Singapore
Registry updated 2025-07-25
NCT03175224
APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors
Trial Treatment · Phase 2 · Apollomics Inc.
National Cancer Centre Singapore, Singapore
Registry updated 2025-06-27

All Colorectal cancer trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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