COPD: open trials in United States

99 open trials have a site in United States. Registry data; only the trial team decides who can take part.

NCT07125053
COPD Resources, Education, and Activity Designed for You Study
Trial Treatment · Rush University Medical Center
Rush University Medical Center, Chicago
Registry updated 2026-10-08
NCT00307281
Emphysema Research Registry and Biosample Repository
Research · University of Pittsburgh
University of Pittsburgh Emphysema/COPD Research Center, Pittsburgh
Registry updated 2026-10-06
NCT07072039
Evaluation of the Paramedic Evaluation for Acute COPD Exacerbation
Trial Treatment · University of Massachusetts, Worcester
University of Massachusetts Chan Medical School, Worcester
Registry updated 2026-10-06
NCT06512064
Acoustic Waveform Respiratory Evaluation
Trial Treatment · Indiana University
Indiana University, Indianapolis · University of Pittsburgh, Pittsburgh
Registry updated 2026-10-05
NCT06959095
Depemokimab as an Extended Treatment Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation
Trial Treatment · Phase 3 · GlaxoSmithKline
Bakersfield · Baltimore · Bradenton · Brandon · Chicago · Clarkston · Corsicana · Dallas · Flint · Franklin · Greenville · Henderson · Hialeah · Houston · Las Vegas · Loxahatchee Groves · McKinney · Miami · Miami Lakes · Modesto · Newport Beach · North Massapequa · Orange City · Palmetto Bay · Palm Springs · Pearland · Pensacola · Reno · Riverdale · Rock Hill · St Louis · Stonecrest · Tamarac · Tampa · The Villages · Wilmington · Winston-Salem
Registry updated 2026-10-05
NCT06961214
Depemokimab as an Extended Treatment Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation (ENDURA-2)
Trial Treatment · Phase 3 · GlaxoSmithKline
Adairsville · Allen Park · Atlanta · Aurora · Austin · Bangor · Baton Rouge · Boise · Brooksville · Chicago · Cordele · Dallas · Detroit · Doral · DuBois · El Paso · Fall River · Fort Lauderdale · Garden City · Houston · Knoxville · Lafayette · Lampasas · Las Vegas · Miami · Miami Lakes · Moorestown · Morgantown · Morrow · Mount Kisco · Naples · New Port Richey · New Windsor · Ocala · Orlando · Ormond Beach · Palmetto Bay · Pembroke Pines · Philadelphia · Richmond · Rockville · San Antonio · Sewell · Sheffield · Shelby · Shreveport · Spartanburg · St. Petersburg · Troy · Union · Webster
Registry updated 2026-10-05
NCT07838519
Personalizing Veterans' Lung Cancer Screening and Diagnosis
Trial Treatment · VA Office of Research and Development
Rocky Mountain Regional VA Medical Center, Aurora, CO, Aurora · Jesse Brown VA Medical Center, Chicago, IL, Chicago · Kansas City VA Medical Center, Kansas City, MO, Kansas City · Robley Rex VA Medical Center, Louisville, KY, Louisville · Tennessee Valley Healthcare System Nashville Campus, Nashville, TN, Nashville · Salisbury W.G. (Bill) Hefner VA Medical Center, Salisbury, NC, Salisbury · VA Puget Sound Health Care System Seattle Division, Seattle, WA, Seattle
Registry updated 2026-10-05
NCT06283966
A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease
Trial Treatment · Phase 3 · AstraZeneca
Abilene · Albany · Albuquerque · Amarillo · Anderson · Ann Arbor · Apple Valley · Athens · Aurora · Austin · Beavercreek · Blue Ash · Boise · Boston · Bountiful · Boynton Beach · Bradenton · Bronxville · Brooklyn · Brownsville · Camp Hill · Canoga Park · Cape Coral · Castroville · Charleston · Chattanooga · Chicago · Clearwater · Cleveland · Columbia · Columbus · Crystal River · Cudahy · Cullman · Cutler Bay · Dallas · Denver · DuBois · Edgewater · Elizabethton · El Paso · Englewood · Exton · Fairhope · Fayetteville · Flint · Forney · Fort Lauderdale · Fort Myers · Franklin · Fremont · Gaffney · Gardena · Garden Grove · Georgetown · Gilbert · Glen Burnie · Glendale · Grand Island · Grants Pass · Greensboro · Greenville · Gulfport · Hialeah · Hollywood · Homestead · Houston · Huntersville · Huntsville · Inglewood · Kansas City · Katy · Kerrville · Kingwood · Kissimmee · Lafayette · Lake City · Lakeland · Lake Worth · La Mesa · La Palma · Las Vegas · Lawrence · Lewisville · Lexington · Liberty · Lincoln · Lomita · Long Beach · Los Alamitos · Loxahatchee Groves · Marion · Massapequa · McAllen · McKinney · Medford · Mesa · Miami · Miami Lakes · Milwaukee · Mission Viejo · Missoula · Mobile · Monroe · Morehead City · Morgantown · Morristown · Mullica Hill · Naples · Newport Beach · Newport News · Newton · New Windsor · New York · Norfolk · Norman · North Hollywood · Ocala · Ogden · Oklahoma City · Olive Branch · Omaha · Orlando · Ormond Beach · Oxon Hill · Paducah · Paris · Peachtree Corners · Pembroke Pines · Philadelphia · Phoenix · Pierre · Plano · Plantation · Pomona · Potomac · Raleigh · Rapid City · Richmond · Roseburg · Sacramento · Salisbury · Salt Lake City · San Bernardino · San Diego · San Dimas · Santa Ana · Savannah · Sheffield · Shreveport · Sioux City · Sioux Falls · Southfield · Spartanburg · Spokane · Statesville · St Louis · St. Petersburg · Suffolk · Sun City Center · Tamarac · Tampa · Tarzana · Tempe · The Bronx · Thousand Oaks · Toledo · Toms River · Tucker · Tucson · Tullahoma · Tulsa · Union · Union City · Valparaiso · Van Nuys · Vestal · Victoria · Vista · Waco · Washington D.C. · West Jordan · Westminster · West Valley City · Wichita · Wichita Falls · Wilmington · Winfield · Winston-Salem · Wylie · Zachary
Registry updated 2026-10-02
NCT05934565
Mindful Steps 2.0: Promoting Physical Activity in Patients With COPD and HF
Trial Treatment · Beth Israel Deaconess Medical Center
VA Boston, Boston · BIDMC, Boston
Registry updated 2026-09-29
NCT05986214
Developing an Intervention to Optimize Virtual Care Adoption for COPD Management
Trial Treatment · VA Office of Research and Development
VA Bedford HealthCare System, Bedford, MA, Bedford · VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA, Boston
Registry updated 2026-09-29
NCT04930289
Global Utilization And Registry Database for Improved preservAtion of doNor LUNGs
Research · Paragonix Technologies
Johns Hopkins University, Baltimore · Massachusetts General Hospital, Boston · University of Virginia, Charlottesville · Baylor Scott & White Research Institute, Dallas · The University of Texas Southwestern Medical Center, Dallas · Duke Lung Transplant Clinic, Durham · Houston Methodist Hospital, Houston · Mayo Clinic- Jacksonville, Jacksonville · Temple University Hospital, Philadelphia · St. Joseph's Hospital and Medical Center, Phoenix · University of Pittsburgh Medical Center, Pittsburgh · University of California San Francisco, San Francisco · Stanford Medicine, Stanford · Montefiore Hospital, The Bronx
Registry updated 2026-09-18
NCT06035120
An Evaluation of the AeriSeal System for CONVERTing Collateral Ventilation Status in Patients With Severe Emphysema
Trial Treatment · Pulmonx Corporation
Brigham Lung Center, Boston · Beth Israel Deaconess Medical Center, Boston · University of Chicago Medical Center, Chicago · Northwestern University, Chicago · Cleveland VA Northeast, Cleveland · University of Texas, Southwestern, Dallas · Henry Ford Hospital, Detroit · Inova Fairfax Hospital, Falls Church · Saint Francis Hospital and Medical Center (Trinity Health of New England), Hartford · Fort Sanders Regional Medical Center (StatCare), Knoxville · University of Kentucky, Lexington · UCHealth - Medical Center of the Rockies, Loveland · Medical College of Wisconsin (MCW), Milwaukee · Orlando Health, Orlando · OSF Saint Francis Medical Center, Peoria · Penn Medicine, Philadelphia · Temple University, Philadelphia · Banner University Medical Center, Phoenix · Allegheny General Hospital, Pittsburgh · University of Pittsburgh Medical Center (UPMC), Pittsburgh
Registry updated 2026-09-17
NCT07816835
Nebulizer Versus Handheld Maintenance Therapy for Patients With COPD
Trial Treatment · Phase 4 · COPD Foundation
Midwest Chest Consultants, P.C., Saint Charles · Southeastern Research Center, Winston-Salem
Registry updated 2026-09-14
NCT07512687
Titrated Ambulatory Oxygen in Fibrotic ILD and COPD With Isolated Exertional Hypoxemia
Trial Treatment · State University of New York at Buffalo
State University of New York at Buffalo Jacobs School of Medicine and Biomedical Sciences, Buffalo
Registry updated 2026-09-09
NCT07059091
Clinical Trial of Omalizumab for Allergen Sensitized and Exposed Individuals With COPD
Trial Treatment · Phase 2 · Johns Hopkins University
University of Michigan, Ann Arbor · Johns Hopkins University, Baltimore · University of Alabama, Birmingham · University of Illinois at Chicago, Chicago · Northwestern University, Chicago · Rush University Medical Center, Chicago · University of Vermont, Colchester · National Jewish Health, Denver · Henry Ford Health, Detroit · Duke University Medical Center, Durham · Baylor College of Medicine, Houston · University of Iowa, Iowa City · University of Florida, Jacksonville · University of Kansas Medical Center, Kansas City · Vanderbilt University Medical Center, Nashville · Cornell University, New York · Columbia University, New York · Mount Sinai - Icahn School of Medicine, New York · Temple University, Philadelphia · University of Pittsburgh, Pittsburgh · University of San Francisco, San Francisco · Pacific Northwest Airways - VA Puget Sound Healthcare System, Seattle, Seattle · University of Arizona- Tuscon, Tucson
Registry updated 2026-09-04
NCT06883305
A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00006)
Trial Treatment · Phase 3 · AstraZeneca
Albuquerque · Atlanta · Baltimore · Buffalo · Chicago · Clearfield · Clearwater · Columbia · Columbus · Cortland · Cudahy · Cutler Bay · Dallas · DeBary · DuBois · Farmington Hills · Foley · Forney · Fort Worth · Franklin · Gainesville · Garden Grove · High Point · Homestead · Horseheads · Houston · Humble · Johnson City · Kerrville · Kings Mountain · Las Vegas · Lithonia · Mansfield · Massapequa · Meridian · Miami · Millville · Milwaukee · Missoula · Mobile · Morgantown · Munster · New Bern · Newport Beach · North Dartmouth · Oklahoma City · Orlando · Palos Hills · Papillion · Philadelphia · Phoenix · Rincon · Rock Hill · Saint Cloud · Sewell · Sheffield · St Louis · Tampa · The Bronx · Toms River · Torrance · Tucson · Wilmington · Winfield · Winston-Salem
Registry updated 2026-09-03
NCT07118306
COPD Exacerbation Follow Up
Research · Viz.ai, Inc.
Cooper University Health Care, Cherry Hill · Inova Fairfax Hospital, Falls Church · Aurora St. Luke's Medical Center, Milwaukee · Advocate Lutheran General Hospital, Park Ridge · Thomas Jefferson University, Philadelphia
Registry updated 2026-09-02
NCT05257681
Inter-lobar Fissure Completion in Patients With Failed Bronchoscopic Lung Volume Reduction
Trial Treatment · Beth Israel Deaconess Medical Center
Beth Israel Deaconess Medical Center, Boston
Registry updated 2026-08-28
NCT07037836
Inhaled Treprostinil (Tyvaso Nebulizer) For COPD Patients With Hypoxemia
Trial Treatment · Phase 2 · Bastiaan Driehuys
Duke Asthma Allergy and Airway Center, Durham
Registry updated 2026-08-27
NCT07031336
Photon-counting CT in Chest Imaging
Trial Treatment · Duke University
Duke University Hospital, Durham
Registry updated 2026-08-26
NCT07714252
Virtual Nurse and Social Worker Palliative Care Team to Improve Quality of Life in Veterans With Heart Failure or COPD
Trial Treatment · VA Office of Research and Development
Rocky Mountain Regional VA Medical Center, Aurora, CO, Aurora · Cheyenne VA Medical, Cheyenne, WY, Cheyenne · Lebanon VA Medical Center, Lebanon, PA, Lebanon · VA Long Beach Healthcare System, Long Beach, CA, Long Beach · Phoenix VA Health Care System, Phoenix, AZ, Phoenix · Providence VA Medical Center, Providence, RI, Providence · Overton Brooks VA Medical Center, Shreveport, LA, Shreveport
Registry updated 2026-08-24
NCT05879211
Goal Concordant Care Learning Laboratory
Trial Treatment · Duke University
Duke Health, Durham
Registry updated 2026-08-06
NCT07747805
GLP-1 Agonists for Lung Function Improvement and Muscle Restoration in COPD
Trial Treatment · Phase 2 · The Cleveland Clinic
Cleveland Clinic, Cleveland
Registry updated 2026-08-05
NCT06376994
Multi-Center Clean Air Randomized Controlled Trial in COPD
Trial Treatment · Phase 3 · JHSPH Center for Clinical Trials
University of Michigan, Ann Arbor · Johns Hopkins, Baltimore · University of Maryland, Baltimore · University of Alabama, Lung Health Center, Birmingham · Beth Israel Deaconess Medical Center, Boston · Cleveland Clinic, Cleveland · University of Iowa, Iowa City · Dartmouth Hitchcock, Lebanon · University of California, Los Angeles, Los Angeles · Tidal Health, Salisbury · Reading Hospital, West Reading
Registry updated 2026-07-31
NCT07177339
eValuating the Efficacy and Safety of InitiatinG depemokImab earLy therApy iN Chronic Obstructive Pulmonary Disorder (COPD) With Type 2 Inflammation
Trial Treatment · Phase 3 · GlaxoSmithKline
Allen Park · Bangor · Boise · Bowling Green · Brandon · Clarkston · Cordele · Crystal River · Dallas · Dearborn · DeSoto · Doral · DuBois · Dunwoody · Edmond · Greenacres City · Greenville · Henderson · Hialeah · Hollywood · Houston · Katy · Knoxville · Lake Charles · Lakewood · Las Vegas · Mesquite · Miami · Miami Lakes · Newport Beach · Orlando · Reno · Rock Hill · Shreveport · Stafford · West Chester · Winston-Salem
Registry updated 2026-07-28

All COPD trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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