COPD: open trials in United States

99 open trials have a site in United States. Registry data; only the trial team decides who can take part.

NCT07275359
Investigating Senolytic Properties in Pulmonary Rehabilitation and Metformin in COPD Exacerbations
Trial Treatment · Phase 1 · Duke University
Duke Asthma Allergy and Airway Center, Durham
Registry updated 2026-11-03
NCT07914010
Reducing Exposure With Air Cleaners and Technology
Trial Treatment · University of California, Berkeley
University of California, Berkeley, Berkeley · University of California San Francisco, San Francisco · Brightline Defense Project, San Francisco
Registry updated 2026-11-03
NCT07684820
To Evaluate the Effect of EXPD-101/FXS7553 Compared With Placebo in Patients With COPD Over 52 Weeks of Treatment
Trial Treatment · Phase 2 · Expedition Therapeutics, Inc
International Clinical Research, Altamonte Springs · Lynn Institute of Denver, Aurora · Synergy Healthcare LLC, Bradenton · Burke Internal Medicine, Inc., Burke · K2 Medical Research Winter Garden LLC, Clermont · Remington-Davis Research, Columbus · Nature Coast Clinical Research, Crystal River · Horizon Clinical Research Group, Cypress · Clinical Research Associates of Central Pa, LLC, DuBois · Leading Edge Research, LLC, Encino · Hannibal Regional Healthcare System, Inc., Hannibal · DM Clinical Research, Indianapolis, Indianapolis · University of Kansas Medical Center Research Institute, Inc, Kansas City · Clinical Site Partners, LLC Leesburg dba Flourish Research, Leesburg · Headlands Research-Twin Cities, Maplewood · Metroplex Pulmonary and Sleep Center, McKinney · Suncoast Research Group, LLC Miami - Little Havana dba Flourish Research, Miami · California Medical Research Associates Inc., Northridge · Optimal Research Sites, Orange City · DM Clinical Research - Philadelphia, Philadelphia · DM Clinical Research - Phoenix, Phoenix · Eximia Research, Raleigh · Centricity Research Rincon Pulmonology, Rincon · Clinical Research of Rock Hill, Rock Hill · Carolina Research Center, Inc, Shelby · Care Access Research - Shreveport, Shreveport · DM Clinical Research, Tomball, Tomball · Cotton O'Neil Clinical Research Center, Topeka · Tidewater Clinical Research, Virginia Beach
Registry updated 2026-10-28
NCT05572632
Rehabilitation in Safety-net Environments (RISE) to Improve Outcomes in Vulnerable Patients With COPD
Trial Treatment · University of California, San Francisco
Zuckerberg San Francisco General (ZSFG) Hospital, San Francisco · Maxine Hall Health Center (MHHC), San Francisco · Southeast Health Center (SEHC), San Francisco
Registry updated 2026-10-27
NCT07135427
Genetic Variation in IgG in Alpha 1 Antitrypsin Deficiency
Trial Treatment · Phase 4 · University of Alabama at Birmingham
University of Alabama at Birmingham, Birmingham
Registry updated 2026-10-27
NCT07705737
Rademikibart IV for Acute Asthma and COPD Exacerbation
Trial Treatment · Phase 2 · Connect Biopharm LLC
Columbus Clinical Services LLC, Miami · Pharmax Research of South Florida, Inc, Miami · Washington University- Cardiovascular Imaging and Clinical Research Core Laboratory, St Louis
Registry updated 2026-10-27
NCT07725939
A Study of 24 to 52 Weeks Treatment to Evaluate The Efficacy And Safety of Galvokimig in Study Participants With Moderate-to-Severe Chronic Obstructive Pulmonary Disease (COPD) With Chronic Bronchitis
Trial Treatment · Phase 2 · UCB Biopharma SRL
Copd01 50001, Boerne · Copd01 50003, Columbus · Copd01 50002, DuBois · Copd01 50006, McKinney · Copd01 50019, Medford · Copd01 50011, Miami · Copd01 50020, North Charleston · Copd01 50008, Rincon · Copd01 50004, Rock Hill · Copd01 50013, Seattle · Copd01 50009, Spartanburg · Copd01 50005, Tomball · Copd01 50010, Union · Copd01 50016, Westminster
Registry updated 2026-10-27
NCT07555483
A Non-inferiority Pharmacokinetic and Safety/Tolerability Study of Two Different Doses of Weekly SC Alpha1-PI 15% Compared With Corresponding Standard IV Alpha1-PI in Participants With Alpha1-Antitrypsin Deficiency (AATD)
Trial Treatment · Phase 3 · Grifols Therapeutics LLC
GC2501 Study Site 106, Birmingham · GC2501 Study Site 101, Charleston · GC2501 Study Site 104, Cleveland · GC2501 Study Site 109, Dallas · GC2501 Study Site 103, Gainesville · GC2501 Study Site 100, Los Angelas · GC2501 Study Site 105, Miami · GC2501 Study Site 102, Phoenix · GC2501 Study Site 108, Rochester · GC2501 Study Site 107, Scottsdale
Registry updated 2026-10-26
NCT01776398
Collection of Airway, Blood and/or Urine Specimens From Subjects for Research Studies
Research · Weill Medical College of Cornell University
Weill Cornell Medical College and Weill Cornell Medical Center, Department of Genetic Medicine, New York
Registry updated 2026-10-23
NCT07646587
A Study of WIN378 in Participants With Moderate to Severe COPD (Sirius)
Trial Treatment · Phase 2 · Windward Bio
WB Contracted Clinical Research Site, Charlotte · WB Contracted Clinical Research Site, DuBois · WB Contracted Clinical Research Site, Jacksonville · WB Contracted Clinical Research Site, Los Angeles · WB Contracted Clinical Research Site, McKinney · WB Contracted Clinical Research Site, Medford · WB Contracted Clinical Research Site, Miami Lakes · WB Contracted Clinical Research Site, North Dartmouth · WB Contracted Clinical Research Site, Waxahachie
Registry updated 2026-10-23
NCT07363694
A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate to Severe Chronic Obstructive Pulmonary Disease
Trial Treatment · Phase 2/3 · Pfizer
Paul A. Shapero, MD, PA, Bangor · University of Alabama at Birmingham - Lung Health Center, Birmingham · South Texas Medical Research Institute, Inc., DBA TTS Research, Boerne · Ten20 Clinical Research, Carrollton · Northwell Health Physician Partners at Chappaqua, Chappaqua · Bogan Sleep Consultants, LLC, Columbia · Horizon Clinical Research Group, Cypress · Baylor University Medical Center (Research Office), Dallas · Baylor University Medical Center, Dallas · Alina Clinical Trials, LLC., Dallas · Baylor Scott & White Advanced Lung Disease Specialists, Dallas · Revival Research Institute, LLC, Dearborn · SEC Clinical Research, Dothan · Clinical Research Associates of Central Pa, LLC, DuBois · Cpcc-Research Llc, East Point · Exordia Medical Research Inc, Fall River · AA Medical Research Center, Flint · New York Presbyterian Queens, Flushing · Clinical Trials Center of Middle Tennessee, LLC, Franklin · Velocity Clinical Research, Gaffney, Gaffney · Finlay Medical Research, Greenacres City · ASHA Clinical Research-Munster, LLC, Hammond · Henderson Clinical Trials, Henderson · Premier Research Center, LLC, Hendersonville · Houston Pulmonary Sleep and Allergy Associates, Houston · Greater Heights Memorial Pulmonary and Sleep, Houston · University of Kansas Medical Center, Kansas City · Clinical Research Specialists, LLC, Kissimmee · IMAX Clinical Trials, La Palma · Advanced Pulmonary Research Institute, Loxahatchee Groves · Methodist Hospital Southlake, Merrillville · Reed Medical Research, Miami · Pulmonary Associates of Mobile, P.C., Mobile · Northern Westchester Hospital, Mount Kisco · NewportNativeMD, Inc., Newport Beach · Infinity Medical Research, North Dartmouth · California Medical Research Associates, Northridge · HCA Florida Ocala Imaging Center, Ocala · Ocala Lung and Critical Care Associates, Ocala · Renstar Medical Research, Ocala · Temple University Hospital, Philadelphia · Pulmonary Associates, PA, Phoenix · Temple Health Oaks, Phoenixville · Health Concepts, Rapid City · Centricity Research Rincon Pulmonology, Rincon · Clinical Research of Rock Hill, Rock Hill · Institute of HealthCare Assessment d/b/a Apex Clinical Research, San Diego · Sherman Clinical Research, Sherman · Revive Research Institute, Inc, Southfield · Velocity Clinical Research, Spartanburg, Spartanburg · Washington University School of Medicine, St Louis · Barnes-Jewish Hospital, St Louis · Washington University School-Cardiovascular Imaging and Clinical Research Core Laboratory, St Louis · Barnes-Jewish Hospital Investigational Drug Service, St Louis · Coastal Pulmonary and Critical Care, P.L.C., St. Petersburg · Coastal Medical Research Institute, LLC, St. Petersburg · Clinical Research Trials of Florida, Inc., Tampa · Toledo Institute of Clinical Research Inc., Toledo · Oakland Medical Research, Troy · Layrek Clinical Research, Tulsa · Southeastern Research Center, Winston-Salem · Salem Chest Specialists, Winston-Salem · Clinical Site Partners, LLC dba Flourish Research, Winter Park · Southern Clinical Research, LLC, Zachary
Registry updated 2026-10-22
NCT07610395
Trial Comparing the Safety and Efficacy of Two Different Oral VPV Doses With Placebo as Treatment for RV in Participants With COPD
Trial Treatment · Phase 2 · Altesa Biosciences, Inc.
Velocity Clinical Research, Anderson, Anderson · Velocity Clinical Research - Binghamton, Binghamton · Synergy Health, Bradenton · Brooklyn Clinical Research, Brooklyn · Remington Davis, Inc., Columbus · Zenos Clinical Research, LLC, Dallas · Verexa Health, Dearborn · Clinical Research Associates of Central Pa, LLC, DuBois · Covenant Critical Pulmonary Care, East Point · Tekton Research, Edmond · Bioluminux Clinical Research New Jersey, Hamilton · 310 Clinical Research, LLC, Inglewood · CRC Kings Mountain, Kings Mountain · Activian Clinical Research - Kingwood, Kingwood · AMR Clinical - Las Vegas, Las Vegas · Epic Clinical Research, LLC, Lewisville · AMR Clinical - Lexington, Lexington · Patient First Clinical Trials (PFCTRIALS), Lutherville · Velocity Clinical Research, Medford, Medford · Medquest Translational Sciences, Miami Lakes · VM Clintrials, Miami Lakes · Hometown Urgent Care - Milford, Milford · Velocity Clinical Research, Mobile, Mobile · Bioluminux Clinical Research Illinois, Naperville · NewportNativeMD, Inc., Newport Beach · Preferred Primary Care Physicians - St. Clair, Pittsburgh · Clinical Research of Rock Hill, Rock Hill · Apex Clinical Research, San Diego · Guthrie Medical Group, PC, Sayre · Accelerated Clinical Trials, Snellville · Velocity Clinical Research, Spartanburg, Spartanburg · Metropolitan Clinical Research Center, Tamarac · AMR Clinical - Tempe, Tempe · Activian Clinical Research - Tomball, Tomball · Oakland Medical Research, Troy · Velocity Clinical Research Union, Union · Velocity Clinical Research, Valparaiso, Valparaiso
Registry updated 2026-10-22
NCT06891755
Bronchoscopic RElease of Air Trapped in Hyperinflated Emphysematous Lung - Study 3
Trial Treatment · Apreo Health, Inc.
University of Michigan, Ann Arbor · University of Alabama at Birmingham, Birmingham · Beth Israel Deaconess Medical Center, Boston · University of Chicago, Chicago · Cleveland Clinic Foundation, Cleveland · The Ohio State University, Columbus · Clinical Research Associates of Central Pennsylvania, DuBois · Inova Health Care Services, Falls Church · Banner Health, Gilbert · Houston Methodist/Primary Critical Care, Houston · Mayo Clinic, Jascksonville · University of Kansas Medical Center Research Institute, Kansas City · Medical College of Wisconsin, Milwaukee · Orlando Health, Orlando · OSF St Francis Medical Center, Peoria · Temple University, Philadelphia · University of Pittsburgh Medical Center, Pittsburgh · University of California at Davis, Sacramento
Registry updated 2026-10-19
NCT07133880
Compare the Effects of Nebulizer Versus Inhaler Based Therapy for COPD Using Long-acting Bronchodilators
Trial Treatment · Phase 4 · University of Tennessee Graduate School of Medicine
The University of Tennessee Graduate School of Medicine, Knoxville
Registry updated 2026-10-19
NCT04302272
STRIVE Post-Market Registry Study
Research · Olympus Corporation of the Americas
AnMed Health, Anderson · University of Maryland, Baltimore · Beth Israel Decaconess, Boston · University of Chicago, Chicago · Northwestern University, Division of Pulmonary and Critical Care Medicine, Chicago · University of Miami, Coral Gables · Baylor Scott & White Research Institute, Dallas · University of Texas, Southwestern, Dallas · Duke University Medical Center, Durham · Memorial Hospital at Gulfport, Gulfport · Penn State Milton S. Hershey Medical Center, Hershey · University of Texas Health Science Center at Houston, Houston · El Camino, Taft Center for Clinical Research, Mountain View · Temple University, Philadelphia · Dignity Health St Joseph's Hospital and Medical Center, Phoenix · LSU Health Shreveport, Shreveport
Registry updated 2026-10-16
NCT06634810
Comprehensive Patient-Centered Home-based Care Coaching for COPD Self-management
Trial Treatment · Icahn School of Medicine at Mount Sinai
Ichan School of Medicine at Mount Sinai, New York
Registry updated 2026-10-16
NCT07587658
This After Market Study is Seeing if Dupilumab Plus Usual Standard of Care (SOC) is Better Than Usual Care Alone for Adult Participants After a Severe Chronic Obstructive Pulmonary Disease (COPD) Flare-Up Requiring Hospitalization
Trial Treatment · Phase 4 · Regeneron Pharmaceuticals
Inspira Medical Center Mullica Hill, Mullica Hill
Registry updated 2026-10-16
NCT07612878
The Study of Chronic Obstructive Pulmonary Disease (COPD) Participants Treated With Dupilumab (STRIDE) Registry
Research · Sanofi
Ohio State University, Columbus · Duke, Durham · The Respire Institute, Houston · IU Health Pulmonology & Critical Care Medicine, Indianapolis · Activian Clinical Research, Kingwood · University of Kansas, Lawrence · The Lung & Sleep Institute of North Texas, North Richland Hills
Registry updated 2026-10-15
NCT07119229
A Multi Center Study Testing a New Implant for Adults With Severe Emphysema
Trial Treatment · Pulmair Medical, Inc.
Beth Israel Deaconess Medical Center, Boston · Northwestern University, Chicago · Medical College of Wisconsin, Milwaukee · University of California San Francisco, San Francisco
Registry updated 2026-10-14
NCT07873632
Study to Evaluate the Effects of Oral Glyceryl Guiacolate (Guaifenesin, GGE) on Sputum Rheology in Subjects With Mucus Hypersecretion
Trial Treatment · Phase 4 · University of North Carolina, Chapel Hill
Marsico Lung Institute, Chapel Hill
Registry updated 2026-10-14
NCT06878261
A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00007)
Trial Treatment · Phase 3 · AstraZeneca
Research Site, Adairsville · Research Site, Anderson · Research Site, Ann Arbor · Research Site, Atlanta · Research Site, Baltimore · Research Site, Bay Pines · Research Site, Birmingham · Research Site, Boerne · Research Site, Bowling Green · Research Site, Boynton Beach · Research Site, Charlotte · Research Site, Clearwater · Research Site, Colchester · Research Site, Columbia · Research Site, Concord · Research Site, Cordele · Research Site, Cullman · Research Site, Decatur · Research Site, El Paso · Research Site, Evanston · Research Site, Evansville · Research Site, Everett · Research Site, Fayetteville · Research Site, Fleming Island · Research Site, Fort Eisenhower · Research Site, Gaffney · Research Site, Grants Pass · Research Site, Hannibal · Research Site, Hendersonville · Research Site, Hinsdale · Research Site, Horsham · Research Site, Houston · Research Site, Indianapolis · Research Site, Inglewood · Research Site, Jacksonville · Research Site, Kansas City · Research Site, Kenosha · Research Site, Knoxville · Research Site, Lebanon · Research Site, Leesburg · Research Site, Lewisville · Research Site, Little River · Research Site, Los Angeles · Research Site, Margate · Research Site, McKinney · Research Site, Mesquite · Research Site, Miami · Research Site, Miami Lakes · Research Site, Minneapolis · Research Site, New Britain · Research Site, Ocala · Research Site, Oklahoma City · Research Site, Owensboro · Research Site, Palmetto Bay · Research Site, Palo Alto · Research Site, Phoenix · Research Site, Pittsburgh · Research Site, Potomac · Research Site, Rapid City · Research Site, Redding · Research Site, Rosedale · Research Site, San Antonio · Research Site, San Diego · Research Site, Savannah · Research Site, Sayre · Research Site, Scottsdale · Research Site, Spartanburg · Research Site, Springfield · Research Site, Staten Island · Research Site, Syracuse · Research Site, The Bronx · Research Site, Tulsa · Research Site, Union · Research Site, Williamsburg · Research Site, Wilmington · Research Site, Winter Park
Registry updated 2026-10-09
NCT07125053
COPD Resources, Education, and Activity Designed for You Study
Trial Treatment · Rush University Medical Center
Rush University Medical Center, Chicago
Registry updated 2026-10-08
NCT07759245
A Study of Brenipatide (LY3537031) in Adult Participants With Moderate-to-Severe Chronic Obstructive Pulmonary Disease (COPD)
Trial Treatment · Phase 2 · Eli Lilly and Company
University of Alabama at Birmingham, Birmingham · Brigham and Women's Hospital, Boston · Premier Pulmonary Critical Care and Sleep, Denison · National Jewish Health Medical Center, Denver · Clinical Research Associates of Central PA, DuBois · Baylor College of Medicine Medical Center, Houston · Indiana University Health University Hospital, Indianapolis · Paramount Clinical Research - Data Point Clinical Research, Kirkland · Prime Clinical Research - Lewisville, Lewisville · Headlands Research-Twin Cities, Maplewood · Millennium Medical Research - Miami, Miami · Deluxe Health Center, Miami Lakes · IU Health Ball Memorial Hospital, Inc., Muncie · NewportNativeMD, Inc., Newport Beach · Florida Institute For Clinical Research, LLC, Orlando · Institute of HealthCare Assessment d/b/a Apex Clinical Research, San Diego · Revive Research Institute, Inc, Southfield · Axis Clinical Trials - Westchester, Westchester
Registry updated 2026-10-08
NCT00307281
Emphysema Research Registry and Biosample Repository
Research · University of Pittsburgh
University of Pittsburgh Emphysema/COPD Research Center, Pittsburgh
Registry updated 2026-10-06
NCT07072039
Evaluation of the Paramedic Evaluation for Acute COPD Exacerbation
Trial Treatment · University of Massachusetts, Worcester
University of Massachusetts Chan Medical School, Worcester
Registry updated 2026-10-06

All COPD trials and the map

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