Crohn's disease: open trials in Netherlands

41 open trials have a site in Netherlands. Registry data; only the trial team decides who can take part.

2024-518296-56-00
A clinical study of MK-7240 for the treatment of Crohn’s disease (MK-7240-008)
Trial Treatment · Phase 3 · Merck Sharp & Dohme LLC
Amsterdam UMC Stichting, Amsterdam · Universitair Medisch Centrum Groningen, Groningen · Radboud universitair medisch centrum Stichting, Nijmegen · Sint Franciscus Vlietland Groep Stichting, Rotterdam · Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC), Rotterdam · Stichting Elisabeth-TweeSteden Ziekenhuis, Tilburg · Bernhoven B.V., Uden · Universitair Medisch Centrum Utrecht, Utrecht
Registry updated 2026-11-08
NCT06006039
The Role of IL-23-Responsive Immune Cell Subsets in Post-Operative Recurrence in Patients With Crohn's Disease.
Research · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Amsterdam UMC, Amsterdam
Registry updated 2026-11-04
NCT06937099
Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight
Trial Treatment · Phase 3 · Eli Lilly and Company
Amsterdam UMC Locatie VUMC, Amsterdam · Radboudumc, Nijmegen · Ikazia Ziekenhuis, Rotterdam · Erasmus Medisch Centrum, Rotterdam · Universitair Medisch Centrum Utrecht, Utrecht
Registry updated 2026-11-04
NCT05923073
A Study of Guselkumab in Pediatric Participants With Moderately to Severely Active Crohn's Disease
Trial Treatment · Phase 3 · Janssen Research & Development, LLC
Erasmus Medisch Centrum 1, Rotterdam
Registry updated 2026-11-03
NCT07196722
A Study of Icotrokinra in Participants With Moderately to Severely Active Crohn's Disease
Trial Treatment · Phase 2/3 · Janssen Research & Development, LLC
Amsterdam UMC Stichting, Amsterdam · Academisch Ziekenhuis Maastricht, Maastricht · Radboud universitair medisch centrum Stichting, Nijmegen · Sint Franciscus Vlietland Groep Stichting, Rotterdam
Registry updated 2026-11-03
NCT07363044
A Prospective Randomised Study of Treatment Selection Based on Epigenetic Markers Versus Standard of Care Treatment Selection in Adults With CROHN's Disease
Trial Treatment · Alimentiv Inc.
Flevoziekenhuis Hospitaalweg 1, Almere Stad · Amsterdam UMC, Amsterdam · OLVG Oost, Amsterdam · Catharina Ziekenhuis, Eindhoven · Maastricht UMC, Maastricht · St. Antonius Ziekenhuis, Nieuwegein · Radboudumc, Nijmegen · Elisabeth-TweeSteden Ziekenhuis (ETZ), Tilburg · Universitair Medisch Centrum Utrecht, Utrecht
Registry updated 2026-11-03
NCT07499232
A Study of Guselkumab Versus Risankizumab in Participants With Moderately to Severely Active Crohn's Disease
Trial Treatment · Phase 3 · Janssen Research & Development, LLC
Maastricht UMC, Maastricht · Radboud Umcn, Nijmegen · St. Elisabeth Ziekenhuis, Tilburg
Registry updated 2026-11-03
NCT07577843
A Study of JNJ-78934804 in Participants With Moderately to Severely Active Crohn's Disease
Trial Treatment · Phase 3 · Janssen Research & Development, LLC
Amsterdam UMC Stichting, Amsterdam · Radboud universitair medisch centrum Stichting, Nijmegen · Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC), Rotterdam · Stichting Elisabeth-TweeSteden Ziekenhuis, Tilburg
Registry updated 2026-11-03
NCT06233461
A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Crohn's Disease
Trial Treatment · Phase 2 · Takeda
Amsterdam UMC Stichting, Amsterdam · Zuyderland Medisch Centrum Stichting, Geleen · Elisabeth-Tweesteden Ziekenhuis, Tilburg
Registry updated 2026-11-02
NCT06430801
A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)
Trial Treatment · Phase 3 · Merck Sharp & Dohme LLC
Amsterdam UMC, Amsterdam · Universitair Medisch Centrum Groningen, Groningen · Stichting Radboud Universitair Medisch Centrum, Nijmegen · NOVAMED ROBERT KOTERAS, Opole · Sint Franciscus Vlietland Groep Stichting, Rotterdam · Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC), Rotterdam · Stichting Elisabeth-TweeSteden Ziekenhuis, Tilburg · Bernhoven B.V., Uden · Universitair Medisch Centrum Utrecht, Utrecht
Registry updated 2026-11-02
NCT07184931
An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease
Trial Treatment · Phase 3 · Sanofi
Amsterdam · Christchurch · Lower Hutt · Nijmegen · Tauranga · Tilburg · Wellington
Registry updated 2026-10-21
NCT07184944
A Maintenance Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease
Trial Treatment · Phase 3 · Sanofi
Tilburg
Registry updated 2026-10-21
NCT05995353
A Study to Assess Adverse Events, Change in Disease Activity, and How Intravenous and Subcutaneous Risankizumab Moves Through the Body of Pediatric Participants With Moderately to Severely Active Crohn's Disease
Trial Treatment · Phase 3 · AbbVie
Academisch Medisch Centrum, Amsterdam
Registry updated 2026-10-20
NCT06819878
A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease
Trial Treatment · Phase 3 · Hoffmann-La Roche
Amsterdam UMC Stichting, Amsterdam · Rijnstate Ziekenhuis Stichting, Arnhem · Radboud universitair medisch centrum Stichting, Nijmegen · Stichting Zuyderland Medisch Centrum, Sittard-Geleen · Stichting Elisabeth-TweeSteden Ziekenhuis, Tilburg · Universitair Medisch Centrum Utrecht, Utrecht
Registry updated 2026-10-16
2026-525197-19-00
A clinical trial to assess the efficacy and safety of ontunisertib compared to placebo in patients with fibrostenosing Crohn’s disease
Trial Treatment · Phase 2 · Agomab Spain S.L.U.
Amsterdam UMC Stichting, Amsterdam · Universitair Medisch Centrum Groningen, Groningen · Radboud universitair medisch centrum Stichting, Nijmegen · Universitair Medisch Centrum Utrecht, Utrecht
Registry updated 2026-10-14
NCT07647640
Prospective Evaluation of Flare Detection in IBD With Digital Biomarkers: Bring Your Own Device Study
Research · Maastricht University Medical Center
Maastricht UMC, Maastricht · Franciscus Hospital, Rotterdam · Jeroen Bosch Hospital, 's-Hertogenbosch
Registry updated 2026-10-13
NCT06405087
A Long-Term Extension Study of Vedolizumab in Children and Teenagers With Ulcerative Colitis (UC) or Crohn's Disease (CD)
Trial Treatment · Phase 3 · Takeda
Radboud universitair medisch centrum Stichting, Nijmegen
Registry updated 2026-10-09
NCT04844606
A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn's Disease (SHINE-ON)
Trial Treatment · Phase 3 · Eli Lilly and Company
Erasmus Medisch Centrum, Rotterdam
Registry updated 2026-10-07
NCT05509777
A Study of Mirikizumab (LY3074828) in Pediatric Participants With Crohn's Disease
Trial Treatment · Phase 3 · Eli Lilly and Company
Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC), Rotterdam
Registry updated 2026-10-07
NCT06548542
Study of Targeted Therapies for the Treatment of Adult Participants With Moderate to Severe Crohn's Disease
Trial Treatment · Phase 2 · AbbVie
Academisch Medisch Centrum, Amsterdam · Universitair Medisch Centrum Groningen, Groningen · Stichting Elisabeth-TweeSteden Ziekenhuis, Tilburg · Universitair Medisch Centrum Utrecht, Utrecht
Registry updated 2026-09-25
NCT07582458
Modafinil for Debilitating Fatigue in Quiescent Inflammatory Bowel Disease MODIFI-IBD Trial)
Trial Treatment · Phase 2/3 · Radboud University Medical Center
Rijnstate, Arnhem · Radboudumc, Nijmegen
Registry updated 2026-09-14
2025-521590-13-00
Crohn’s Head-to-Head Assessing Risankizumab Versus Guselkumab for One Year
Trial Treatment · Phase 3 · Janssen Cilag International
Academisch Ziekenhuis Maastricht, Maastricht · Radboud universitair medisch centrum Stichting, Nijmegen · Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC), Rotterdam · Stichting Elisabeth-TweeSteden Ziekenhuis, Tilburg · Universitair Medisch Centrum Utrecht, Utrecht
Registry updated 2026-08-28
NCT03571373
PIBD-SETQuality: the Inception Cohort and Safety Registry
Research · Erasmus Medical Center
Erasmus MC - Sophia Children's Hospital, Rotterdam
Registry updated 2026-08-11
NCT06100289
A Study of Vedolizumab in Children and Teenagers With Ulcerative Colitis or Crohn's Disease
Trial Treatment · Phase 3 · Takeda
Stichting Radboud Universitair Medisch Centrum, Nijmegen
Registry updated 2026-08-03
2025-524129-42-00
Methotrexate in paediatric and adolescent Crohn’s disease: an observational study
Trial Treatment · Phase 4 · Amsterdam UMC Stichting
Amsterdam UMC Stichting, Amsterdam · Medisch Spectrum Twente, Enschede · Universitair Medisch Centrum Groningen, Groningen · Universitair Medisch Centrum Utrecht, Utrecht
Registry updated 2026-07-30

All Crohn's disease trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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