Crohn's disease: open trials in South Africa

• NCT07298421

  A Study to Assess the Pharmacokinetics, Effectiveness and Safety of Afimkibart for Induction and Maintenance Therapy in Children With Moderately to Severely Active Crohn's Disease

  Trial Treatment · Phase 3 · Hoffmann-La Roche

  IATROS International, Bloemfontein · Emmed Research, Pretoria

  Registry updated 2026-11-05

• NCT06430801

  A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)

  Trial Treatment · Phase 3 · Merck Sharp & Dohme LLC

  Life Kingsbury Hospital (Site 4000), Cape Town · Panorama Medical Centre (Site 4001), Cape Town · Spoke Research (Site 4003), Cape Town · Wits Clinical Research (Site 4004), Johannesburg · Private Practice - Dr. M.N. Rajabally (Site 4007), Plumstead · Wits Clinical Research-Chris Hani Baragwanath Hospital (Site 4005), Soweto

  Registry updated 2026-11-02

• NCT06958536

  A Study to Investigate Efficacy and Safety of Brivekimig in Participants With Crohn's Disease

  Trial Treatment · Phase 2 · Sanofi

  Cape Town · Durban · Johannesburg · Johannesburg · Plumstead

  Registry updated 2026-11-02

• NCT07184931

  An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease

  Trial Treatment · Phase 3 · Sanofi

  Cape Town · Claremont · Durban · East London · Kempton Park · KwaZulu-Natal

  Registry updated 2026-10-21

• NCT07184944

  A Maintenance Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease

  Trial Treatment · Phase 3 · Sanofi

  Cape Town · Durban · Kempton Park

  Registry updated 2026-10-21

All Crohn's disease trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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