Depression: open trials in Canada

75 open trials have a site in Canada. Registry data; only the trial team decides who can take part.

NCT03665831
Deep TMS for Comorbid Depression and Cognitive Impairment in Older Adults
Trial Treatment · Rotman Research Institute at Baycrest
Rotman Research Institute at Baycrest, Toronto
Registry updated 2025-10-27
NCT06763081
Pharmacogenomics of Selective Serotonin Reuptake Inhibitor (SSRI)-Induced Behavioural Activation
Research · University of Manitoba
Shared Health Facilities, Winnipeg · University of Manitoba College of Pharmacy, Winnipeg
Registry updated 2025-09-08
NCT06619366
The Impact of Coach-guided Risk Communication on the Risk of Major Depression
Trial Treatment · Dalhousie University
Faculty of Medicine, Halifax
Registry updated 2025-09-02
NCT07140575
rTMS for Youth Inpatients With Depression
Trial Treatment · Sunnybrook Health Sciences Centre
Sunnybrook Health Sciences Centre, Toronto
Registry updated 2025-08-24
NCT07113665
Magnetic Resonance-Guided Focused Ultrasound Bilateral Capsulotomy for Refractory Anorexia Nervosa With Comorbid Obsessive Compulsive Disorder or Major Depressive Disorder
Trial Treatment · Phase 1 · Sunnybrook Health Sciences Centre
Sunnybrook Health Sciences Centre, Toronto
Registry updated 2025-08-14
NCT07094789
Focused Ultrasound Neuromodulation in Patients With Treatment-Resistant Depression
Trial Treatment · Sunnybrook Health Sciences Centre
Sunnybrook Health Sciences Centre, Toronto
Registry updated 2025-08-11
NCT07108257
Magnetic Resonance-Guided Focused Ultrasound Bilateral Capsulotomy for the Treatment of Refractory Bipolar Depression
Trial Treatment · Sunnybrook Health Sciences Centre
Sunnybrook Health Sciences Centre, Toronto
Registry updated 2025-08-06
NCT07033780
Theta-Burst Stimulation to Treat Depression
Trial Treatment · Phase 1 · Centre for Addiction and Mental Health
Centre for Addiction and Mental Health, Toronto
Registry updated 2025-06-24
NCT06978452
Behavioural Development, Long-term Outcomes and Opportunities to Optimize Youth Mental Health Trajectories
Research · Douglas Mental Health University Institute
Centre intégré universitaire de santé et de services sociaux (CIUSSS) de l'Ouest-de-l'Île-de-Montréal, Montreal
Registry updated 2025-05-18
NCT01980147
Skills for Wellness
Trial Treatment · Nova Scotia Health Authority
Nova Scotia Health Authority, Halifax
Registry updated 2025-05-14
NCT02752542
Personalized Indications for CBT and Antidepressants in Treating Depression
Trial Treatment · Phase 4 · Nova Scotia Health Authority
Nova Scotia Health Authority, Halifax
Registry updated 2025-05-14
NCT03601026
Genetic Counselling in the Prevention of Mental Health Consequences of Cannabis Use
Trial Treatment · Nova Scotia Health Authority
Nova Scotia Health Authority, Halifax
Registry updated 2025-05-14
NCT06404320
Physical Activity Program for TRD
Trial Treatment · Unity Health Toronto
St. Michael's Hospital, Unity Health Toronto, Toronto
Registry updated 2025-04-30
NCT05295888
Temporal Interference and Depression
Trial Treatment · Unity Health Toronto
Interventional Psychiatry Program, St. Michael's Hospital - Unity Health Toronto, Toronto
Registry updated 2025-04-24
NCT06719427
qEEG Brain Signature of Depression & Neuromodulation-induced Recovery
Trial Treatment · Phase 1 · Sunnybrook Health Sciences Centre
Sunnybrook Health Sciences Centre, North York · Sunnybrook Health Sciences Centre, Toronto
Registry updated 2025-03-03
NCT04935619
Extended Effects of Cannabis Abstinence on Clinical Symptoms and Cognition in Depression
Trial Treatment · Centre for Addiction and Mental Health
Centre for Addiction and Mental Health, Toronto
Registry updated 2025-02-24
NCT06807528
Intermittent Fasting for Inflammation and Depression in Spinal Cord Injury
Trial Treatment · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Parkwood Institute, St Joseph's Health Care London, London
Registry updated 2025-02-21
NCT03272698
ECT with Ketamine Anesthesia Vs High Intensity Ketamine with ECT Rescue for Treatment-Resistant Depression
Trial Treatment · Phase 4 · University of Saskatchewan
Royal University Hospital, Saskatoon
Registry updated 2025-01-23
NCT05139862
Neurocardiac Predictors of Treatment Response to RTMS in Depression
Trial Treatment · University of British Columbia
Non-Invasive Neurostimulation Therapies (NINET) Laboratory, UBC Department of Psychiatry, Vancouver
Registry updated 2024-12-24
NCT06163625
The Impact of Working Memory and Reward Markers on DLPFC Activity in Treatment-resistant Depression
Trial Treatment · Unity Health Toronto
Unity Health Toronto, Toronto
Registry updated 2024-12-19
NCT06732089
Digital Interventions for Adults with Treatment-Resistant Depression: a Pilot Study
Research · Unity Health Toronto
St. Michael's Hospital, Unity Health Toronto, Toronto
Registry updated 2024-12-13
NCT05423275
Light and Ion Maintenance In Treatment for Depression (LIMIT-D): Feasibility Study
Trial Treatment · University of British Columbia
Djavad Mowafaghian Centre for Brain Health, Vancouver
Registry updated 2024-12-09
NCT05813093
Interleaved TMS-fMRI in Ultra-treatment Resistant Depression
Trial Treatment · Sunnybrook Health Sciences Centre
Sunnybrook Health Sciences Centre, Toronto
Registry updated 2024-11-15
NCT05527509
Risk and Resiliency Factors in the RCMP: A Prospective Investigation
Trial Treatment · University of Regina
University of Regina, Regina
Registry updated 2023-11-28
NCT05583747
E-field Guided iTBS for Treatment Resistant Depression
Trial Treatment · Centre for Addiction and Mental Health
Centre for Addiction and Mental Health, Toronto · Poul Hansen Family Centre for Depression, Toronto Western Hospital, Toronto
Registry updated 2023-09-26

All Depression trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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