Depression: open trials in United States

• NCT07216404

  Psilocybin-Assisted Therapy for the Treatment of Major Depressive Disorder in Patients With Non-Small Cell Lung Cancer

  Trial Treatment · Phase 2 · Alan Davis

  Ohio State University Comprehensive Cancer Center, Columbus

  Registry updated 2026-05-14

• NCT07230990

  Mechanisms Of Orbitofrontal Stimulation in Depression

  Trial Treatment · Subha Subramanian

  Beth Israel Deaconess Medical Center, Boston

  Registry updated 2026-05-14

• NCT07560878

  Synaptic Mechanisms of Continuous Theta Burst Stimulation in Depression

  Trial Treatment · Early phase 1 · Mclean Hospital

  McLean Hospital, Belmont

  Registry updated 2026-05-13

• NCT05004987

  Aβ Dynamics in LLMD

  Trial Treatment · Phase 4 · NYU Langone Health

  NYU Langone Health, New York · Nathan S. Kline Institute for Psychiatric Research, Orangeburg

  Registry updated 2026-05-06

• NCT05786066

  The Impact of AMPA Receptor Blockade on Ketamine's Anti-Suicidal Effects

  Trial Treatment · Phase 2 · Yale University

  VA Connecticut Healthcare System, West Haven

  Registry updated 2026-05-06

• NCT05915013

  Alpha-Amino-3-Hydroxy-5-Methyl-4- Isoxazole Propionic Acid Receptor Components of the Anti-Depressant Ketamine Response

  Trial Treatment · Phase 1 · Yale University

  Yale University, New Haven

  Registry updated 2026-05-06

• NCT06748209

  Establishing Mobile Transcranial Magnetic Stimulation

  Trial Treatment · Phase 4 · Medical University of South Carolina

  Medical Univerity of South Carolina, Charleston

  Registry updated 2026-05-06

• NCT07479550

  Study of Psilocybin Under Anesthesia Controlled by EEG

  Trial Treatment · Phase 2 · Stanford University

  Stanford University, Stanford

  Registry updated 2026-05-06

• NCT07512284

  Mindfulness Engaged Neurostimulation for Depression (MEND II)

  Trial Treatment · Phase 2 · University of California, San Diego

  UC San Diego Health Psychiatry, San Diego

  Registry updated 2026-05-06

• NCT06110897

  RESISTance Exercise for Depression Trial

  Trial Treatment · University of Wisconsin, Madison

  Iowa State University, Ames · University of Wisconsin - Madison, Madison

  Registry updated 2026-05-05

• NCT07028216

  Mindful Self-compassion for Anxiety and Depression: Impact of Delivery Method

  Trial Treatment · Georgetown University

  Georgetown University Medical Center, Washington D.C.

  Registry updated 2026-05-05

• NCT06345859

  Regulation of Affect and Physiology in Depression

  Trial Treatment · Phase 2 · University of Southern California

  University of Southern California, Los Angeles

  Registry updated 2026-05-04

• NCT07566104

  Group PACBT for Depression

  Trial Treatment · Phase 2 · University of California, Los Angeles

  UCLA Semel Institute, Los Angeles

  Registry updated 2026-05-04

• NCT02122562

  Ketamine Alcohol (in Treatment-Resistant Depression)

  Trial Treatment · Phase 2 · Mark Niciu

  University of Iowa Health Care, Iowa City

  Registry updated 2026-05-01

• NCT05892744

  Establishing Multimodal Brain Biomarkers for Treatment Selection in Depression

  Trial Treatment · Phase 4 · University of Texas at Austin

  Health Discovery Building (HDB), 1601 Trinity St., Bldg B., Z0600, Austin

  Registry updated 2026-05-01

• NCT06982820

  Self Neuro-modulation Therapy for Major Depressive Disorder (MDD) With Anhedonia

  Trial Treatment · GrayMatters Health Ltd.

  Houston Center For Advanced Psychiatric Treatment, Houston · Butler Hospital, Providence

  Registry updated 2026-05-01

• NCT05617495

  Mindfulness-Based fMRI Neurofeedback for Depression

  Trial Treatment · Columbia University

  Northeastern University, Boston · Columbia University Irving Medical Center, New York

  Registry updated 2026-04-29

• NCT06897670

  Identifying Cerebral Hemodynamic Patterns in Mood Disorders and Mild Cognitive Impairment: A Functional Near-Infrared Spectroscopy (fNIRS) Study

  Research · Mayo Clinic

  Mayo Clinic, Rochester

  Registry updated 2026-04-29

• NCT06938841

  Maintenance rTMS for Depression (Maitr-De)

  Trial Treatment · University of California, San Diego

  Weill Cornell Medicine, New York · University of California San Diego, San Diego

  Registry updated 2026-04-29

• NCT07280065

  REVEAL Study - Diagnostic Testing for PTSD Using the Senseye Diagnostic Tool

  Trial Treatment · Phase 3 · Senseye, Inc.

  University of Colorado Anschutz Medical Campus, Aurora · Lindus Health (Virtual Study Site), Boston · Lowcountry Center for Veterans Research, Charleston · Velocity Clinical Research, Meridian · Savannah VA Clinic, Savannah

  Registry updated 2026-04-29

• NCT07493317

  Neutralizing Interleukin (IL)-6

  Trial Treatment · Phase 2 · Icahn School of Medicine at Mount Sinai

  Icahn School of Medicine at Mount Sinai, New York

  Registry updated 2026-04-29

• NCT06752759

  Nebulized Ketamine for the Treatment of Major Depressive Disorder

  Trial Treatment · Phase 3 · Theresa Jacob, PhD, MPH

  Maimonides Medical Center, Brooklyn

  Registry updated 2026-04-24

• NCT04751331

  Neural Response to Inflammatory Challenge in Major Depressive Disorder

  Trial Treatment · Phase 1/2 · Laureate Institute for Brain Research, Inc.

  Laureate Institute for Brain Research, Tulsa

  Registry updated 2026-04-21

• NCT03833206

  A Phase I/II Study of PDC-1421 for Treating Depression in Cancer Patients

  Trial Treatment · Phase 1/2 · BioLite, Inc.

  Cedars-Sinai Health System, Los Angeles

  Registry updated 2026-04-20

• NCT07002554

  Bright Light Therapy for Depressed Geriatric Inpatients

  Trial Treatment · Phase 2 · Medical University of South Carolina

  Medical University of South Carolina Institute of Psychiatry Senior Care Unit, Charleston

  Registry updated 2026-04-16

All Depression trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

Report an error