Endometrial cancer trials in Australia

In Australia 34 Also abroad 394

34 trials · From ClinicalTrials.gov, checked 10 November 2026. Ask the study team whether a trial fits you.

Phase 1Taking people
A Study of Sofe-M in Participants With Selected Advanced Solid Tumors
Where
Adelaide, QLD
Age
18 years and over
People
575 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT06400472 · EU 2024-511238-11-00
Phase 2Taking people
A Study to Learn More About How Well Treatment With Sevabertinib (BAY 2927088) Tablets Works and How Safe it is in Participants Who Have a Solid Tumor With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)
Where
Blacktown, Southport, Sydney
Age
18 years and over
People
111 worldwide
Run by
Bayer
See details and how to joinNCT06760819 · EU 2024-517419-62-00
Phase 3Taking people
Study to Assess the Efficacy and Safety of Rina-S Compared to Treatment of Investigator's Choice in Participants With Endometrial Cancer
Where
Campbelltown, Camperdown, Gosford, Heidelberg, Joondalup, Kingswood, Waratah
Age
18 years and over
People
660 worldwide
Run by
Genmab
See details and how to joinNCT07166094
Phase 3Taking people
A Study to Investigate Mocertatug Rezetecan Compared With Chemotherapy in Participants With Endometrial Cancer After Platinum-based Chemotherapy and Immunotherapy (BEHOLD-Endometrial01)
Where
Auchenflower, Dubbo, Herston
Age
18 years and over
People
600 worldwide
Run by
GlaxoSmithKline
See details and how to joinNCT07286331 · EU 2025-523362-25-00
Early phase 1Taking people
177Lu-anti-PD-L1 sdAb in Metastatic Solid Tumors
Where
Adelaide, Gosford, Kingswood, Murdoch, Southport, Wollongong
Age
18 years and over
People
30
Run by
Radiopharm Theranostics, Ltd
See details and how to joinNCT06305962
Phase 1/2Taking people
EIK1005-002: A Clinical Research Study Evaluating EIK1005, a Werner Helicase Inhibitor, as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors Including Microsatellite Instability High (MSI-H) Tumors
Where
Ballarat, Camperdown, Frankston, Saint Leonards, Waratah
Age
18 years and over
People
160 worldwide
Run by
Eikon Therapeutics
See details and how to joinNCT07262619 · EU 2026-525248-13-00
Phase 3Taking people
Symbiotic-GYN-18: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Advanced or Recurrent MMR-proficient Endometrial Cancer
Where
Campbelltown, Frankston, Toowoomba
Age
18 years and over
People
600 worldwide
Run by
Pfizer
See details and how to joinNCT07578649 · EU 2026-525584-40-00
Phase 1Taking people
A Study of MGC026 in Participants With Advanced Solid Tumors
Where
Auchenflower, Heidelberg, Kurralta Park
Age
18 years and over
People
394 worldwide
Run by
MacroGenics
See details and how to joinNCT06242470
Phase 2Taking people
A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
Where
Camperdown, Chermside, Clayton, Hobart, Hyde Park
Age
18 years and over
People
740 worldwide
Run by
Daiichi Sankyo
See details and how to joinNCT06172478 · EU 2023-507641-29-00
Phase 1/2Taking people
A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02)
Where
Blacktown, Mount Kuring-Gai, St Leonards, Subiaco, Woolloongabba
Age
18 years and over
People
680 worldwide
Run by
Daiichi Sankyo
See details and how to joinNCT06330064 · EU 2023-509632-26-00
Phase 1/2Taking people
A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors
Where
Frankston, Sydney
Age
18 years and over
People
616 worldwide
Run by
Verastem, Inc.
See details and how to joinNCT07020221
Phase 3Taking people
A Clinical Study of the Anti-cancer Effects of an Investigational Therapy or Chemotherapy in Patients With Recurring Uterine Cancer
Where
Adelaide, Clayton, Gosford, Melbourne, Nowra, Saint Albans, South Brisbane, Wollongong
Age
18 years and over
People
480 worldwide
Run by
BioNTech SE
See details and how to joinNCT06340568 · EU 2023-507525-42-00
Phase 1/2Taking people
A Clinical Trial to Test if the Investigational Drug BNT329 is Safe and Potentially Beneficial for People With Advanced Solid Tumors Known to Express the Tumor Marker CA19-9
Where
Clayton, Heidelberg
Age
18 years and over
People
245 worldwide
Run by
BioNTech SE
See details and how to joinNCT07186842 · EU 2025-522613-26-00
Phase 2Taking people
Adjuvant Therapy in POLE-Mutated and p53-Wildtype/NSMP Early Stage Endometrial Cancer RAINBO BLUE & TAPER
Where
Clayton, Darwin, Frankston, Garran, Herston, Liverpool, Parkville, South Brisbane, St Leonards, Waratah, Westmead
Age
18 years and over
People
393 worldwide
Run by
Canadian Cancer Trials Group
See details and how to joinNCT05640999
Phase 1/2Taking people
A Phase I/IIa Study of AZD8205 Given Alone or Combined, in Participants With Advanced/Metastatic Solid Malignancies
Where
Clayton, Melbourne, Nedlands
Age
18 years and over
People
460 worldwide
Run by
AstraZeneca
See details and how to joinNCT05123482 · EU 2022-502759-70-01
Phase 3Taking people
A Study to Compare Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone as Treatment in Participants With Mismatch Repair Proficient Endometrial Cancer (MK-2870-033/TroFuse-033/GOG-3119/ENGOT-en29)
Where
Blacktown, Brisbane, Melbourne, Nedlands
Age
18 years and over
People
1,123 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT06952504 · EU 2024-519331-42-00
Phase 3Taking people
DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer
Where
Blacktown, East Melbourne, Nedlands, South Brisbane
Age
18 years and over
People
600 worldwide
Run by
AstraZeneca
See details and how to joinNCT06989112 · EU 2023-508056-19-00
Phase 1/2Taking people
FOG-001 in Locally Advanced or Metastatic Solid Tumors
Where
Melbourne, South Brisbane
Age
18 years and over
People
619 worldwide
Run by
Parabilis Medicines, Inc.
See details and how to joinNCT05919264
Phase 1/2Taking people
Study of AZD9574 as Monotherapy and in Combination With Anti-cancer Agents in Participants With Advanced Solid Malignancies
Where
Darlinghurst, Melbourne, Randwick
Age
18 years to 130 years
People
695 worldwide
Run by
AstraZeneca
See details and how to joinNCT05417594 · EU 2023-504984-17-00
Phase 1/2Taking people
Phase I/IIa Study of AZD5335 as Monotherapy and Combination Therapy in Participants With Solid Tumors
Where
Liverpool, Melbourne
Age
18 years to 130 years
People
622 worldwide
Run by
AstraZeneca
See details and how to joinNCT05797168 · EU 2022-502576-23-00
Phase 1/2Taking people
The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
Where
Bedford Park, Camperdown, Clayton, Nedlands, South Brisbane
Age
12 years and over
People
300 worldwide
Run by
PMV Pharmaceuticals, Inc
See details and how to joinNCT04585750
Phase 1/2Taking people
Study of AVZO-021 in Patients With Advanced Solid Tumors
Where
Macquarie University, Wollongong
Age
18 years and over
People
430 worldwide
Run by
Avenzo Therapeutics, Inc.
See details and how to joinNCT05867251
Phase 1/2Taking people
Study of REGN4018 (Ubamatamab) Administered Alone or in Combination With Cemiplimab in Adult Patients With Recurrent Ovarian Cancer or Other Recurrent Mucin-16 Expressing (MUC16+) Cancers
Where
Melbourne, Randwick
Age
18 years and over
People
890 worldwide
Run by
Regeneron Pharmaceuticals
See details and how to joinNCT03564340 · EU 2024-510783-23-00
Phase 1Taking people
A Study of KIVU-107 in Participants With Locally Advanced or Metastatic Solid Tumors
Where
Adelaide, Brisbane, Camperdown, Geelong, Sydney
Age
18 years and over
People
76 worldwide
Run by
Kivu Bioscience Inc.
See details and how to joinNCT07229313
Phase 3Taking people
Sentinel Node Biopsy in Endometrial Cancer
Where
Auchenflower, Brisbane, Buderim, Camperdown, Everton Park, Heidelberg, Herston, Liverpool, Melbourne, Parkville, South Brisbane, Southport, Spring Hill
Age
18 years and over
People
760 worldwide
Run by
Queensland Centre for Gynaecological Cancer
See details and how to joinNCT04073706