Endometrial cancer: open trials in Germany

32 open trials have a site in Germany. Registry data; only the trial team decides who can take part.

NCT07166094
Study to Assess the Efficacy and Safety of Rina-S Compared to Treatment of Investigator's Choice in Participants With Endometrial Cancer
Trial Treatment · Phase 3 · Genmab
Helios Hospital Berlin-Buch, Berlin · Bonn University Hospital, Bonn · Asklepios Hospital Barmbek, Hamburg · Klinikum Lippe GmbH Pharmacy, Lemgo · Central Whse (Zentrallager), Wiesbaden
Registry updated 2026-11-03
NCT07262619
EIK1005-002: A Clinical Research Study Evaluating EIK1005, a Werner Helicase Inhibitor, as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors Including Microsatellite Instability High (MSI-H) Tumors
Trial Treatment · Phase 1/2 · Eikon Therapeutics
Helios Klinikum Berlin Buch, Berlin · DONAUISAR Klinikum, Deggendorf · Norddeutsches Studienzentrum fur Innovative Onkologie (NIO) Hamatologisch Onkologische Praxis Eppendorf (HOPE), Hamburg
Registry updated 2026-10-30
NCT07022483
A Study of Trastuzumab Deruxtecan Versus Standard of Care Chemotherapy for HER2-Expressing (IHC 3+/2+) Endometrial Cancer in Adjuvant Setting
Trial Treatment · Phase 3 · Daiichi Sankyo
Klinikum Lippe GmbH, Detmold · Universitaetsklinikum Carl Gustav Carus Dresden an der Technischen Universitaet Dresden AöR, Dresden · Universitaetsklinikum Duesseldorf AöR, Duesseldorf · Kliniken Essen-Mitte, Evangelische Huyssens-Stiftung Loc. 1, Essen · Goethe University Frankfurt, Frankfurt Am Main · UNIVERSITÄTSKLINIKUM FREIBURG, Freiburg · University Medical Center Hamburg-Eppendorf, Hamburg · Universitaetsklinikum Ulm AoR, Ulm
Registry updated 2026-10-27
NCT06172478
A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
Trial Treatment · Phase 2 · Daiichi Sankyo
Krankenhaus Nordwest GmbH, Frankfurt
Registry updated 2026-10-26
NCT06330064
A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02)
Trial Treatment · Phase 1/2 · Daiichi Sankyo
Charite Universitaetsmedizin Berlin KöR, Berlin · Vivantes Netzwerk fuer Gesundheit GmbH, Berlin · Staedtisches Klinikum Dresden, Dresden · Universitaetsklinikum Heidelberg AöR, Heidelberg · SLK-Kliniken Heilbronn GmbH, Heilbronn · Universitaet Leipzig, Leipzig · Universitaetsmedizin der Johannes Gutenberg-Universitaet Mainz KöR, Mainz · Universitaet Muenster, Muenster
Registry updated 2026-10-26
NCT06340568
A Clinical Study of the Anti-cancer Effects of an Investigational Therapy or Chemotherapy in Patients With Recurring Uterine Cancer
Trial Treatment · Phase 3 · BioNTech SE
DRK Kliniken Berlin, Berlin · Charite Universitaetsmedizin Berlin KöR, Berlin · Universitaetsklinikum Bonn AöR, Bonn · Technische Universitaet Dresden, Dresden · Kliniken Essen-Mitte, Evangelische Huyssens-Stiftung Loc. 1, Essen · Klinikum Kassel GmbH, Kassel · Universitaetsklinikum Leipzig Aor, Leipzig · LMU Klinikum Muenchen AöR, Munich · Universitaetsklinikum Tuebingen AöR, Tuebingen
Registry updated 2026-10-16
NCT07186842
A Clinical Trial to Test if the Investigational Drug BNT329 is Safe and Potentially Beneficial for People With Advanced Solid Tumors Known to Express the Tumor Marker CA19-9
Trial Treatment · Phase 1/2 · BioNTech SE
St. Josef-Hospital im Katholischen Klinikum Bochum, Bochum · Klinikum der Universität München, München · Universitaetsklinikum Ulm, Ulm
Registry updated 2026-10-15
NCT05640999
Adjuvant Therapy in POLE-Mutated and p53-Wildtype/NSMP Early Stage Endometrial Cancer RAINBO BLUE & TAPER
Trial Treatment · Phase 2 · Canadian Cancer Trials Group
Diak Klinikum Landkreis Schwaebisch Hall, Schwäbisch Hall
Registry updated 2026-10-14
NCT06952504
A Study to Compare Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone as Treatment in Participants With Mismatch Repair Proficient Endometrial Cancer (MK-2870-033/TroFuse-033/GOG-3119/ENGOT-en29)
Trial Treatment · Phase 3 · Merck Sharp & Dohme LLC
Universitaetsklinikum Aachen AöR, Aachen · Charite Universitaetsmedizin Berlin KöR, Berlin · DRK Kliniken Berlin, Berlin · Universitaetsklinikum Bonn AöR, Bonn · Staedtisches Klinikum Dessau, Dessau-Rosslau · Klinikum Lippe GmbH, Detmold · Universitaetsklinikum Carl Gustav Carus Dresden an der Technischen Universitaet Dresden AöR, Dresden · Asklepios Kliniken Hamburg GmbH, Hamburg · Universitaetsklinikum Jena KöR, Jena · Klinikum Kassel GmbH, Kassel · Universitaetsklinikum Schleswig-Holstein AöR, Kiel · Universitaet Leipzig, Leipzig · Universitaet Muenster, Muenster · Klinikum der Technischen Universitaet Muenchen (TUM Klinikum), Munich · Caritas Traegergesellschaft Saarbruecken mbH (CTS), Saarbruecken · Klinikum Mutterhaus der Borromaeerinnen gGmbH, Trier
Registry updated 2026-10-13
NCT06989112
DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer
Trial Treatment · Phase 3 · AstraZeneca
Charite Universitaetsmedizin Berlin KöR, Berlin · Klinikum Chemnitz gGmbH, Chemnitz · Staedtisches Klinikum Dessau, Dessau-Rosslau · Technische Universitaet Dresden, Dresden · Universitaetsklinikum Essen (AoR), Essen · University Medical Center Hamburg-Eppendorf, Hamburg · Klinikum Kassel GmbH, Kassel · Universitaet Leipzig, Leipzig · Universitaetsklinikum Mannheim GmbH, Mannheim · Universitaet Muenster, Muenster · Caritas Traegergesellschaft Saarbruecken mbH (CTS), Saarbruecken
Registry updated 2026-10-13
NCT05255653
Refining Adjuvant Treatment IN Endometrial Cancer Based On Molecular Features
Trial Treatment · Phase 3 · Leiden University Medical Center
Evangelisches Waldkrankenhaus Spandau Krankenhausbetriebs gGmbH, Berlin · Klinikum Lippe GmbH, Detmold · Technische Universitaet Dresden, Dresden · KEM I Evang. Kliniken Essen-Mitte gGmbH, Essen · University Medical Center Hamburg-Eppendorf, Hamburg · Heidelberg ImmunoTherapeutics GmbH, Heidelberg · Klinikverbund Allgaeu gGmbH, Kempten (Allgau) · Universitaetsklinikum Leipzig Aor, Leipzig · RKH Klinken Ludwigsburg-Bietigheim gGmbH, Ludwigsburg · Universitaet Muenster, Muenster · Rotkreuzklinikum Muenchen gGmbH, Munich · Diakonie-Klinikum Schwaebisch Hall gGmbH, Schwaebisch Hall · Universitaetsklinikum Tuebingen AöR, Tuebingen · Universitaetsklinikum Ulm AoR, Ulm · Rems-Murr-Kliniken gGmbH, Winnenden · Klinikum Worms gGmbH, Worms
Registry updated 2026-10-08
NCT05417594
Study of AZD9574 as Monotherapy and in Combination With Anti-cancer Agents in Participants With Advanced Solid Malignancies
Trial Treatment · Phase 1/2 · AstraZeneca
Bayern · Berlin · Heidelberg · Mainz
Registry updated 2026-10-05
NCT05797168
Phase I/IIa Study of AZD5335 as Monotherapy and Combination Therapy in Participants With Solid Tumors
Trial Treatment · Phase 1/2 · AstraZeneca
Charite Universitaetsmedizin Berlin KöR, Berlin · KEM I Evang. Kliniken Essen-Mitte gGmbH, Essen · Medical Center- University of Freiburg, Freiburg im Breisgau · Medizinische Hochschule Hannover, Hanover · Universitaet Leipzig, Leipzig · Universitaetsklinikum Mannheim GmbH, Mannheim · Universitaetsklinikum Regensburg AöR, Regensburg
Registry updated 2026-10-05
NCT04585750
The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
Trial Treatment · Phase 1/2 · PMV Pharmaceuticals, Inc
Universitätsklinikum Augsburg, Augsburg · Universitätsklinikum Essen, Essen · Universitätsklinikum Frankfurt, Frankfurt am Main · Asklepios Klinik Altona, Hamburg · Nationale Centrum für Tumorerkrankungen (NCT) Heidelberg, Heidelberg
Registry updated 2026-10-02
2025-524160-38-00
A clinical trial of belzutifan and other treatments in people with solid tumors or von Hippel-Lindau (VHL)-related tumors (MK-6482-043)
Trial Treatment · Phase 3 · Merck Sharp & Dohme LLC
Universitaetsklinikum Magdeburg AöR, Magdeburg
Registry updated 2026-10-01
NCT06890273
NIS to Examine the Effectiveness and Safety of Durvalumab and Olaparib in Patients With Endometrial Cancer (DUOLife)
Research · AstraZeneca
Amberg · Bad Nauheim · Bautzen · Berlin · Bielefeld · Bonn · Borna · Bottrop · Brandenburg an der Havel · Braunschweig · Cologne · Dessau · Dresden · Ebersberg · Eggenfelden · Essen · Goslar · Greifswald · Gütersloh · Hamburg · Heilbronn · Homburg · Hösbach · Kiel · Krefeld · Kulmbach · Landshut · Leipzig · Limburg · Lüneburg · Magdeburg · Mainz · München · Neuruppin · Neuss · Nuremberg · Plauen · Rotenburg (Wümme) · Siegen · Solingen · Stendal · Torgau · Traunstein · Unna · Wernigerode · Winnenden · Witten · Worms · Zittau
Registry updated 2026-09-30
NCT05489211
Study of Dato-DXd as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Tumours (TROPION-PanTumor03)
Trial Treatment · Phase 2 · AstraZeneca
Berlin · Essen · Hanover · München · Regensburg
Registry updated 2026-09-23
NCT06128551
Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors
Trial Treatment · Phase 1/2 · Revolution Medicines, Inc.
Universitäts Klinikum Köln, Cologne · Klinikum Esslingen GmbH, Esslingen am Neckar · Krankenhaus Bethanien Moers, Moers · Klinkum Nurnberg Paracelsus Medical Unviersity, Nuremberg
Registry updated 2026-09-22
NCT05059444
ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation
Research · Guardant Health, Inc.
Asklepios Klinik Altona, Hamburg · SLK-Kliniken Heilbronn GmbH, Heilbronn · Ludwig Maximilian University Munich, Munich
Registry updated 2026-09-14
NCT05548296
A Phase 2 Study of ACR-368 in Endometrial Adenocarcinoma
Trial Treatment · Phase 2 · Acrivon Therapeutics
KEM I Evang. Kliniken Essen-Mitte gGmbH, Essen · Universitaetsklinikum Muenster AöR, Muenster · Universitaetsklinikum Ulm AoR, Ulm
Registry updated 2026-08-21
NCT07306559
A Study to Test How Well Different Doses of BI 3820768 Are Tolerated by People With Advanced Cancer (Solid Tumours)
Trial Treatment · Phase 1 · Boehringer Ingelheim
LMU Klinikum Muenchen AöR, Munich · Universitaetsklinikum Wuerzburg AöR, Wuerzburg
Registry updated 2026-08-21
2024-519818-31-01
Study to Assess the Efficacy and Safety of Rina-S Compared to Treatment of Investigator’s Choice in Participants With Endometrial Cancer ( RAINFOL-03 )
Trial Treatment · Phase 3 · Genmab A/S
HELIOS Klinikum Berlin Buch GmbH, Berlin · Charite Universitaetsmedizin Berlin KöR, Berlin · Universitaetsklinikum Bonn AöR, Bonn · Klinikum Chemnitz gGmbH, Chemnitz · Universitaetsklinikum Koeln AöR, Cologne · Klinikum Lippe GmbH, Detmold · Technische Universitaet Dresden, Dresden · Universitaetsklinikum Duesseldorf AöR, Duesseldorf · Asklepios Kliniken Hamburg GmbH, Hamburg · Universitaet Leipzig, Leipzig · Klinikum der Technischen Universitaet Muenchen (TUM Klinikum), Munich · DIAK Klinikum Landkreis Schwaebisch Hall gGmbH, Schwaebisch Hall · Helios Dr. Horst Schmidt Kliniken Wiesbaden GmbH, Wiesbaden
Registry updated 2026-08-10
NCT07044336
Puxitatug Samrotecan (AZD8205) Monotherapy vs Chemotherapy in B7-H4-selected Endometrial Cancer (Bluestar-Endometrial01)
Trial Treatment · Phase 3 · AstraZeneca
Klinikum St. Marien Amberg, Amberg · Klinikum Lippe GmbH, Detmold · Technische Universitaet Dresden, Dresden · KEM I Evang. Kliniken Essen-Mitte gGmbH, Essen · Medical Center- University of Freiburg, Freiburg im Breisgau · University Medical Center Hamburg-Eppendorf, Hamburg · Universitaetsklinikum Heidelberg AöR, Heidelberg · SLK-Kliniken Heilbronn GmbH, Heilbronn · Klinikum Kassel GmbH, Kassel · Marienhaus Klinikum Mainz GmbH, Mainz · Universitaetsklinikum Muenster AöR, Muenster · St. Vincenz-Krankenhaus GmbH, Paderborn · Universitaetsklinikum Regensburg AöR, Regensburg · Universitaetsklinikum Ulm AoR, Ulm · Marien Hospital Witten, Witten
Registry updated 2026-07-29
NCT05208762
A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors
Trial Treatment · Phase 1 · Seagen, a wholly owned subsidiary of Pfizer
Charite Universitaetsmedizin Berlin KöR, Berlin
Registry updated 2026-07-22
NCT06906341
Relacorilant in Combination With Different Treatment Regimens in Patients With Gynecological Cancers
Trial Treatment · Phase 2 · Corcept Therapeutics
519, Aachen · 255, Berlin · 520, Kempten
Registry updated 2026-07-16

All Endometrial cancer trials and the map

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