Epilepsy: open trials in Canada

• NCT05667142

  A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures

  Trial Treatment · Phase 3 · Xenon Pharmaceuticals Inc.

  Center for Neurologic Research, Lethbridge · London Health Sciences Center, London · Le Centre Hospitalier de l'Universite' de Montreal (CHUM), Montreal · Children and Women's Health Centre of BC (BC Children's Hospital), Vancouver

  Registry updated 2026-11-02

• NCT05718817

  An Open-label Study of XEN1101 in Epilepsy

  Trial Treatment · Phase 3 · Xenon Pharmaceuticals Inc.

  Center for Neurologic Research, Lethbridge · London Health Sciences Center, London · Le Centre Hospitalier de l'Universite' de Montreal (CHUM), Montreal

  Registry updated 2026-11-02

• NCT07531745

  ASCEND: Safety and Tolerability of ION337 for the Treatment of Dravet Syndrome

  Trial Treatment · Phase 1/2 · Ionis Pharmaceuticals, Inc.

  McGill University Health Center - Research Institute, Montreal

  Registry updated 2026-11-02

• NCT04462770

  A Study of EPX-100 (Clemizole Hydrochloride) in Participants With Dravet Syndrome

  Trial Treatment · Phase 3 · Epygenix

  Children's Hospital of Eastern Ontario Research Institute Inc., Ottawa · Toronto Western Hospital, University Health Network, Toronto · The Hospital for Sick Children, Toronto · UBC Children's Hospital Research Institute, Vancouver

  Registry updated 2026-10-29

• NCT07881185

  Artificial Intelligence for Brain MRI Analysis in Epilepsy

  Research · Istituto Giannina Gaslini

  Multimodal Imaging and Connectome Analysis Laboratory (Montreal Neurological Institute and Hospital, McGill University), Montreal

  Registry updated 2026-10-19

• NCT06908226

  A Study to Investigate LP352 in Children and Adults With Developmental and Epileptic Encephalopathy (DEE)

  Trial Treatment · Phase 3 · Longboard Pharmaceuticals

  The Hospital for Sick Children (SickKids), Toronto

  Registry updated 2026-10-14

• NCT07680322

  Safety and Efficacy of AV078 in Participants With Tuberous Sclerosis Complex (TSC) Refractory Epilepsy (RESTOR-1)

  Trial Treatment · Phase 2 · Aeovian Pharmaceuticals, Inc.

  London Health Sciences Centre, London

  Registry updated 2026-09-29

• NCT06924827

  A Study to Investigate the Transition of Children From 'Artisanal" Cannabidiol (CBD) to Epidiolex

  Trial Treatment · Phase 4 · Elizabeth Donner

  The Hospital for Sick Children, Toronto

  Registry updated 2026-09-11

• NCT07281027

  COMparison Between Anakinra and Tocilizumab in NORSE - "COMBAT-NORSE"

  Trial Treatment · Phase 3 · Yale University

  Western University, London · Hospital for Sick Children, Toronto

  Registry updated 2026-08-19

• NCT07417280

  LIFUS For Neurological Disorders

  Trial Treatment · University Health Network, Toronto

  Toronto Western Hospital, 399 Bathurst St, Toronto

  Registry updated 2026-08-13

• NCT04526093

  Real-World Evidence in Patient-Reported Outcomes for Medical Cannabis (MC-RWE)

  Research · University Health Network, Toronto

  Toronto General Hospital, UHN, Toronto

  Registry updated 2026-07-22

• NCT06455384

  The Genetics Navigator: Evaluating a Digital Platform for Genomics Health Services

  Trial Treatment · Unity Health Toronto

  Mount Sinai Hospital, Toronto · Sunnybrook Hospital, Toronto · The Hospital for Sick Children, Toronto

  Registry updated 2026-06-24

• NCT06138808

  5-SENSE Score Validation Study

  Research · Duke University

  Dalhousie Universiry and Hospital, Dalhousie · Wester University, London

  Registry updated 2026-06-05

• NCT06483061

  Enhanced MRI Imaging in Healthy Participants and Participants With Epilepsy

  Trial Treatment · Phase 2 · University of Alberta

  Peter S. Allen MRI Unit, Edmonton

  Registry updated 2026-05-08

• NCT05485649

  Clinical Outcomes of Pregnant Individuals With Epilepsy - Prospective Study

  Research · University Health Network, Toronto

  University Health Network, Toronto

  Registry updated 2026-05-06

• NCT05503290

  The Lullaby Project as a Musical Intervention for Pregnant Individuals With Epilepsy

  Trial Treatment · University Health Network, Toronto

  University Health Network, Toronto

  Registry updated 2026-05-06

• NCT01694940

  North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)

  Research · Columbia University

  McMaster University, Hamilton

  Registry updated 2026-02-04

• NCT03400371

  Biology of Juvenile Myoclonic Epilepsy

  Research · King's College London

  Hospital for Sick Kids, Toronto

  Registry updated 2025-09-05

• NCT07010276

  Deep Brain Stimulation vs. Vagus Nerve Stimulation for Epileptic Spasms

  Trial Treatment · The Hospital for Sick Children

  The Hospital for Sick Children, Toronto

  Registry updated 2025-06-12

• NCT06262594

  Lemborexant Treatment of Insomnia Linked to Epilepsy

  Trial Treatment · Phase 3 · University of Manitoba

  Health Sciences Centre, Winnipeg

  Registry updated 2025-02-13

• NCT05254730

  Using Micro-filaments to Detect "fast Ripples" and Improve the Identification of the Epileptogenic Zone

  Trial Treatment · Adrien Peyrache

  McGill University, Montreal

  Registry updated 2024-11-20

• NCT05863910

  Real World Evidence on the Use of Medical Cannabis in Pediatrics

  Research · University of Manitoba

  U Manitoba, Winnipeg

  Registry updated 2023-11-30

All Epilepsy trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

Report an error