Epilepsy: open trials in United Kingdom

23 open trials have a site in United Kingdom. Registry data; only the trial team decides who can take part.

NCT05667142
A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures
Trial Treatment · Phase 3 · Xenon Pharmaceuticals Inc.
University Hospital of Wales, Cardiff · St. George's University Hospitals NHS Foundation Trust, London · University College London Hospitals NHS Foundation Trust, London · John Radcliffe Hospital, Oxford · Salford Royal NHS Foundation Trust - Greater Manchester Neuroscience Centre (GMNC), Salford · Mid Yorkshire Hospitals NHS Trust, Wakefield
Registry updated 2026-11-02
NCT05718817
An Open-label Study of XEN1101 in Epilepsy
Trial Treatment · Phase 3 · Xenon Pharmaceuticals Inc.
Queen Elizabeth Hospital Birmingham, Birmingham · Cardiff and Vale UHB, Cardiff · Leeds Teaching Hospitals NHS Trust, Leeds · University College London, London · St George's Hospital NHS Foundation Trust, London · John Radcliffe Hospital, Oxford · Salford Royal NHS Foundation Trust - Greater Manchester Neuroscience Centre (GMNC), Salford
Registry updated 2026-11-02
NCT04462770
A Study of EPX-100 (Clemizole Hydrochloride) in Participants With Dravet Syndrome
Trial Treatment · Phase 3 · Epygenix
Cardiff and Vale University Health Board, Cardiff · Great Ormond Street Hospital for Children, London · Sheffield Children's Hospital, Sheffield
Registry updated 2026-10-29
NCT05419492
A Clinical Study to Evaluate the Safety and Efficacy of ETX101 in Infants and Children With SCN1A-Positive Dravet Syndrome
Trial Treatment · Phase 1/2 · Encoded Therapeutics
Queen Elizabeth Hospital, Glasgow · Great Ormond Street Hospital, London
Registry updated 2026-10-23
NCT05632978
An Observational Study of Epilepsy: Biology and Outcomes Using Real-world Data
Research · Cardiff and Vale University Health Board
Cardiff and Vale UHB, Cardiff
Registry updated 2026-10-23
NCT07881185
Artificial Intelligence for Brain MRI Analysis in Epilepsy
Research · Istituto Giannina Gaslini
University College of London, London
Registry updated 2026-10-19
NCT06908226
A Study to Investigate LP352 in Children and Adults With Developmental and Epileptic Encephalopathy (DEE)
Trial Treatment · Phase 3 · Longboard Pharmaceuticals
Cardiff and Vale University Health Board - University Hospital of Wales (UHW) - Noah's Ark Childr..., Cardiff · NHS Greater Glasgow and Clyde-Glasgow Clinical Research Facility - Queen Elizabeth University Hos..., Glasgow · University College London Hospitals NHS Foundation Trust (UCLH), London · Great Ormond Street Hospital For Children NHS Foundation Trust, London · The Newcastle upon Tyne Hospitals NHS Foundation Trust - Royal Victoria Infirmary (RVI), Newcastle upon Tyne
Registry updated 2026-10-14
NCT07775872
Prospective Natural History Study of POLG Disease
Research · The POLG Foundation
Addenbrooke's Hospital, Cambridge University Hospitals, Cambridge · Great Ormond Street Hospital, London
Registry updated 2026-09-15
NCT07281027
COMparison Between Anakinra and Tocilizumab in NORSE - "COMBAT-NORSE"
Trial Treatment · Phase 3 · Yale University
Great Ormond Street Hospital, London · King's College, London
Registry updated 2026-08-19
NCT05664854
Electrical Impedance Tomography & Selective Stimulation of Vagus Nerve
Trial Treatment · University College, London
National Hospital of Neurology and Neurosurgery, London
Registry updated 2026-05-27
NCT06443463
Long-term Safety and Tolerability of BHV-7000
Trial Treatment · Phase 2 · Biohaven Therapeutics Ltd.
University Hospital of Wales, Cardiff · Queen Elizabeth University Hospital - PPDS, Glasgow · The Walton Centre - PPDS, Liverpool · The Royal London Hospital, London · Royal Free Hospital, London · St Georges NHS Foundation Trust, London · King's College Hospital, London · Royal Victoria Infirmary, Newcastle upon Tyne · John Radcliffe Hospital, Oxford · Salford Royal Hospital - PPDS, Salford · Morriston Hospital, Swansea
Registry updated 2026-05-01
NCT06097195
The Clinical Utility of BioEP in Diagnostic Decision Making in Epilepsy
Trial Treatment · Neuronostics Ltd
Royal Cornwall Hospitals Trust, Truro · The Royal Wolverhampton NHS Trust, Wolverhampton
Registry updated 2026-04-21
NCT06292299
The PARS Study: Paediatric Advanced Respiratory Service Study - An Observational Diagnostic Feasibility Study
Research · NHS Greater Clyde and Glasgow
Royal Hospital for Children Glasgow, Glasgow
Registry updated 2026-04-14
NCT06924086
The Children's Adaptive Deep Brain Stimulation for Epilepsy Trial
Trial Treatment · University College, London
Great Ormond Street Hospital NHS Foundation Trust, London
Registry updated 2026-04-07
NCT06453759
Thalamic Recordings in Children Undergoing SEEG
Trial Treatment · Great Ormond Street Hospital for Children NHS Foundation Trust
Great Ormond Street Hospital for Children, London
Registry updated 2026-02-02
NCT07378397
OPM MEG in Pre-surgical Mapping for Patients With Epilepsy
Research · Aston University
Aston University, Birmingham
Registry updated 2026-01-30
NCT07265362
Compassion Focussed Therapy Informed Psychoeducation and Loving Kindness Meditation for Young People With Epilepsy
Trial Treatment · University of Lincoln
University of Lincoln, Lincoln
Registry updated 2025-12-04
NCT06922175
REACH: RWE Retrospective Study to Evaluate Cenobamate Impact on Health Care Resource Utilization
Research · Aziende Chimiche Riunite Angelini Francesco S.p.A
Institute of Neurosciences NHS Greater Glasgow and Clyde, Glasgow · Epilepsies - The Royal Wolverhampton NHS Trust, Wolverhampton
Registry updated 2025-10-02
NCT03400371
Biology of Juvenile Myoclonic Epilepsy
Research · King's College London
Walton Centre For Neurology and Neurosurgery, Liverpool · Royal London Hospital, London · St Thomas Hospital, London · King's College Hospital NHS Trust, London · Swansea University, Swansea
Registry updated 2025-09-05
NCT06263920
Neurofrailty: A Study of Late-onset Epilepsy and Its Associations
Research · Lancashire Teaching Hospitals NHS Foundation Trust
Lancashire Teaching Hospitals NHS, Preston
Registry updated 2025-04-08
NCT03987633
EMPOWER-1: A Multi-site Clinical Cohort Research Study to Reduce Health Inequality
Research · Future Genetics Limited
Future Genetics, The Science Centre, Wolverhampton Science Park, Wolverhampton
Registry updated 2025-03-10
NCT05725174
Volatile Non-Invasive Biomarkers of Epileptic Seizures
Research · University College London Hospitals
Chalfont Centre for Epilepsy, London · National Hospital For Neurology and Neurosurgery, London
Registry updated 2024-12-06
NCT06065852
National Registry of Rare Kidney Diseases
Research · UK Kidney Association
Zoe Plummer, Bristol
Registry updated 2023-10-04

All Epilepsy trials and the map

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