Familial hypercholesterolaemia: open trials in China

20 open trials have a site in China. Registry data; only the trial team decides who can take part.

NCT05325034
Guideline Oriented Approach To Lipid Lowering In Asia-Pacific
Trial Treatment · Stephen Nicholls
Affiliated Zhongshan Hospital of Dalian University, Dalian
Registry updated 2026-10-08
NCT07058077
A Study of Enlicitide Decanoate (MK-0616, an Oral PCSK9 Inhibitor) in Children and Adolescents With Heterozygous Familial Hypercholesterolemia (MK-0616-029)
Trial Treatment · Phase 2/3 · Merck Sharp & Dohme LLC
Beijing Anzhen Hospital. Capital Medical University (Site 1917), Beijing · Children's Hospital Capital Institute of Pediatrics (Site 1908), Beijing · Guangdong Provincial People's Hospital (Site 1915), Guangzhou · The Children's Hospital of Zhejiang University School of Medicine (Site 1905), Hangzhou · Shanghai Children's Medical Center (Site 1918), Shanghai · Children's Hospital of Fudan University (Site 1906), Shanghai
Registry updated 2026-10-07
NCT06125847
NGGT006 Gene Therapy for Homozygous Familial Hypercholesterolemia
Trial Treatment · Early phase 1 · First Affiliated Hospital Xi'an Jiaotong University
First Affiliated Hospital of Xian Jiaotong University, Xi'an
Registry updated 2026-09-03
NCT07591298
Phase II Clinical Trial to Evaluate the Efficacy and Safety of SYH2070 Injection in Participants With Homozygous Familial Hypercholesterolemia
Trial Treatment · Phase 2 · CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd.
The Second Xiangya Hospital, Changsha
Registry updated 2026-07-31
NCT06597006
Study to Evaluate Safety, Tolerability and Efficacy of Inclisiran in Children With Homozygous Familial Hypercholesterolemia
Trial Treatment · Phase 3 · Novartis Pharmaceuticals
Beijing
Registry updated 2026-07-24
NCT07465263
A Study to Evaluate the SYH2053 Injection in Patients With Heterozygous Familial Hypercholesterolemia (HeFH)
Trial Treatment · Phase 3 · CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd.
Peking University First Hospital, Beijing
Registry updated 2026-07-08
NCT07674368
Rucaparib Monoclonal Antibody for Lorlatinib-Induced Hypercholesterolemia / Mixed
Trial Treatment · Phase 4 · Hunan Cancer Hospital
Hunan Cancer Hospital, Changsha
Registry updated 2026-07-01
NCT07404553
A Study Of SHR-1918 In Participants With Hypercholesterolemia With Inadequate Lipid Control on Statins Plus PCSK9 Inhibitors
Trial Treatment · Phase 2/3 · Beijing Suncadia Pharmaceuticals Co., Ltd
Nanjing First Hospital, Nanjing
Registry updated 2026-06-16
NCT07489209
A Dose-exploration Study of EDP167 in HoFH
Trial Treatment · Phase 2 · Eddingpharm (Zhuhai) Co., Ltd.
Fuwai Hospital, Beijing
Registry updated 2026-05-20
NCT04529967
Child-Parent Familial Hypercholesterolemia Screening
Research · Children's Hospital of Fudan University
Chongqin Medical University Affiliated Children's Hospital, Chongqing · Anhui Provincial Children's Hospital, Hefei · Qidong Women and Children Hospital, Qidong · Weili Yan, Shanghai · Shanxi Provincial Children's Hospital, Taiyuan · Urumqi Children's Hospital, Ürümqi
Registry updated 2026-05-15
NCT06597019
Study to Evaluate Efficacy and Safety of Inclisiran in Children With Heterozygous Familial Hypercholesterolemia
Trial Treatment · Phase 3 · Novartis Pharmaceuticals
Beijing · Shanghai
Registry updated 2026-05-15
NCT07421297
A Study to Evaluate the Safety, Efficacy of SYH2053 as Monotherapy in Chinese Participants With Non-familial Hypercholesterolemia or Mixed Hyperlipidemia
Trial Treatment · Phase 3 · CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd.
Affiliation: Peking University Third Hospital, Beijing
Registry updated 2026-04-07
NCT07353398
Early-phase Study of ART002g1 Injection in HeFH: Safety, Tolerability and Preliminary Efficacy
Trial Treatment · Early phase 1 · Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Shanghai General Hospital, Shanghai
Registry updated 2026-03-17
NCT07421284
A Study to Evaluate the Safety, Efficacy of SYH2053 in Chinese Participants With Non-familial Hypercholesterolemia and Mixed Hyperlipidemia on a Background of Lipid-lowering Therapy
Trial Treatment · Phase 3 · CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd.
Affiliation: Peking University Third Hospital, Beijing
Registry updated 2026-02-19
NCT07133815
Evaluate the Long-term Efficacy and Safety of SHR-1918 in Patients With Homozygous Familial Hypercholesterolemia
Trial Treatment · Phase 2 · Beijing Suncadia Pharmaceuticals Co., Ltd
Xiangya Second Hospital of Central South University, Changsha
Registry updated 2025-08-21
NCT07074236
Pharmacokinetics and Pharmacodynamics Study
Trial Treatment · Phase 1 · Qilu Pharmaceutical Co., Ltd.
The Affiliated Hospital of Qingdao University, Qingdao
Registry updated 2025-07-24
NCT06458010
Clinical Exploration Trial of YOLT-101 in the Treatment of Familial Hypercholesterolemia (FH)
Trial Treatment · Early phase 1 · RenJi Hospital
Deparment of Liver Surgery, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai
Registry updated 2025-04-30
NCT06504043
A Study on Evaluating the Safety of HST101 in Healthy Chinese Participants
Trial Treatment · Phase 1 · Hasten Biopharmaceutical Co., Ltd.
West China Hospital of Sichuan University, Chengdu
Registry updated 2025-03-14
NCT06568471
A Study on Efficacy and Safety of HST101 in Chinese Patients with Hypercholesterolemia
Trial Treatment · Phase 3 · Hasten Biopharmaceutical Co., Ltd.
Beijing Luhe Hospital, Capital Medical Univeristy, Beijing · Beijing Tsinghua Changgeng Hospital, Beijing · Beijing Anzhen Hospital of Capital Medical University, Beijing · Peking University First Hospital, Beijing · Fuwai Hospital ，CAMS&PUMC, Beijing · Binzhou Medical University Hospital, Binzhou · The Third Xiangya Hospital of Central South University, Changsha · The 2nd Xiangya Hospital of Central South University, Changsha · West China Hospital of Sichuan University, Chengdu · Daqingshi People's Hospital, Daqing · Guangdong Provincial People's Hospital, Guangzhou · Heze Municipal Hospital, Heze · Qilu Hospital of Shandong University, Jinan · Nanchang People's Hospital, Nanchang · Shijiazhuang People's Hospital, Shijiazhuang · Tianjin People's Hospital, Tianjin · The First Affiliated Hospital of Wenzhou Medical Univesity, Wenzhou · Zibo Municipal Hospital, Zibo
Registry updated 2025-02-06
NCT05043181
Exosome-based Nanoplatform for Ldlr mRNA Delivery in FH
Trial Treatment · Phase 1 · Tang-Du Hospital
Tangdu Hospital, Air Force Medical University, Xi'an
Registry updated 2021-09-14

All Familial hypercholesterolaemia trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

Report an error