Familial hypercholesterolaemia: open trials in France

9 open trials have a site in France. Registry data; only the trial team decides who can take part.

2024-514595-41-00
Study to evaluate efficacy and safety of inclisiran in children aged 2 to under 12 years of age with homozygous familial hypercholesterolemia
Trial Treatment · Phase 3 · Novartis Pharma AG
Trousseau Hospital, Paris
Registry updated 2026-10-26
NCT07058077
A Study of Enlicitide Decanoate (MK-0616, an Oral PCSK9 Inhibitor) in Children and Adolescents With Heterozygous Familial Hypercholesterolemia (MK-0616-029)
Trial Treatment · Phase 2/3 · Merck Sharp & Dohme LLC
Hospices Civils de Lyon, Bron · Hopital Des Enfants, Toulouse Cedex 9
Registry updated 2026-10-07
NCT05682378
Long-term Safety and Tolerability of Inclisiran in Participants With HeFH or HoFH Who Have Completed the Pediatric ORION-16, ORION-13, ORION-20, or ORION-19 Studies
Trial Treatment · Phase 3 · Novartis Pharmaceuticals
Besançon · Toulouse
Registry updated 2026-09-18
NCT07447648
Assessing the Impact of Intensification of Lipid Lowering Therapy With Guidelines-based Evinacumab Administration on Coronary Plaque Volumes Measured by Coronary Computed Tomography Angiography (CCTA) in Patients With Homozygous Familial Hypercholesterolemia (HoFH)
Research · Fondazione SISA (Societa Italiana per lo Studio della Arteriosclerosi)
Unité de Lipidologie et Prévention Cardiovasculaire, Centre de Compétence Dyslipidémies Rares (CEDRA), Service de Nutrition, Hôpital Pitié-Salpétriêre, Paris
Registry updated 2026-08-21
NCT07427472
"Detection and Follow-up of Coronary Lesions in HeFH (DESTINY-FH Study)"
Trial Treatment · Assistance Publique - Hôpitaux de Paris
APHP-Sorbonne, Pitié Salpêtrière Hospital, Paris · APHP Hospital Saint-Antoine, Paris · Plateau d'investigation clinique (PIC) IHU-ICAN, Paris
Registry updated 2026-06-24
NCT06597019
Study to Evaluate Efficacy and Safety of Inclisiran in Children With Heterozygous Familial Hypercholesterolemia
Trial Treatment · Phase 3 · Novartis Pharmaceuticals
Marseille · Nantes · Paris
Registry updated 2026-05-15
NCT06960902
Study of the Determinants of Coronary Atherosclerosis in Familial Hypercholesterolemia (ATHERO-FH Study)
Trial Treatment · Nantes University Hospital
Chu Dijon Bourgogne, Dijon · CHRU Lille, Lille · Hospices Civils de Lyon, Lyon · Hôpital de la Conception, AP-HM, Marseille · CHU Nantes, Nantes · Hôpital Saint Antoine AP-HP, Paris · Hôpital de la Pitié Salpêtrière - AP-HP, Paris · CHU Rennes, Rennes · CHU Strasbourg, Strasbourg
Registry updated 2026-03-19
NCT06555120
Screening for Familial Hypercholesterolemia in Children
Trial Treatment · Centre Hospitalier Universitaire, Amiens
CHRU Amiens, Amiens
Registry updated 2026-02-12
NCT06894251
Effect of LIMICOL®-NG on Plasma LDL-cholesterol Concentration in Subjects with Moderate Hypercholesterolemia
Trial Treatment · Institut Pasteur de Lille
NutrInvest - Institut Pasteur de Lille, Lille
Registry updated 2025-03-25

All Familial hypercholesterolaemia trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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