Fatty liver disease (MASLD/MASH): open trials in Spain

30 open trials have a site in Spain. Registry data; only the trial team decides who can take part.

NCT06215716
A Study Evaluating Efruxifermin in Subjects With Non-Cirrhotic Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Fibrosis
Trial Treatment · Phase 3 · Akero Therapeutics, Inc
Barcelona · Madrid · Majadahonda · Sabadell · Santander · Seville · Valencia
Registry updated 2026-11-06
NCT07850063
ELEVATE-LIVER: A Study to Test Whether Survodutide Helps Improve Heart Structure and Function in People With Overweight or Obesity and Fatty Liver Disease
Trial Treatment · Phase 3 · Boehringer Ingelheim
Hospital Universitario Virgen de la Arrixaca, El Palmar · Hospital Virgen del Camino, Sanlúcar de Barrameda · Ascires, Valencia
Registry updated 2026-10-30
NCT06632444
LIVERAGE™: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Moderate or Advanced Liver Fibrosis
Trial Treatment · Phase 3 · Boehringer Ingelheim
Complexo Hospitalario Universitario A Coruña, A Coruña · Hospital Universitari Vall d'Hebron, Barcelona · Hospital Universitario Reina Sofia, Córdoba · Hospital Universitario 12 de Octubre, Madrid · Hospital Universitario La Paz, Madrid · Hospital Universitario Puerta de Hierro de Majadahonda, Majadahonda · Complexo Hospitalario Universitario de Pontevedra, Pontevedra · Hospital Universitario Marqués de Valdecilla, Santander · Universidade De Santiago De Compostela, Santiago De Compostela · Hospital Universitario Miguel Servet, Zaragoza
Registry updated 2026-10-28
NCT06632457
LIVERAGE™ - Cirrhosis: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Cirrhosis
Trial Treatment · Phase 3 · Boehringer Ingelheim
Complexo Hospitalario Universitario A Coruña, A Coruña · Hospital Universitari Vall d'Hebron, Barcelona · Hospital Clinic de Barcelona, Barcelona · Hospital Universitario Reina Sofia, Córdoba · Hospital Universitario La Paz, Madrid · Hospital Universitario 12 de Octubre, Madrid · Hospital Universitario Puerta de Hierro de Majadahonda, Majadahonda · Complexo Hospitalario Universitario de Pontevedra, Pontevedra · Universidade De Santiago De Compostela, Santiago De Compostela
Registry updated 2026-10-28
NCT07467512
Exercise for an Aging Liver (EXALIVER)
Trial Treatment · Consorcio Centro de Investigación Biomédica en Red (CIBER)
Hospital General Universitario Gregorio Marañón, Madrid
Registry updated 2026-10-26
NCT07631637
Study to Evaluate ALN-CIDEB in Adults With Fibrotic Metabolic Dysfunction-Associated Steatohepatitis (MASH)
Trial Treatment · Phase 2 · Regeneron Pharmaceuticals
Hospital Universitari Vall d'Hebron, Barcelona · Hospital General Universitario Gregorio Marañón, Madrid · Complexo Hospitalario Universitario de Pontevedra, Pontevedra · Parc Tauli Hospital Universitari, Sabadell · Hospital Universitario Marqués de Valdecilla, Santander · University Hospital Virgen Del Rocio S.L., Sevilla · Hospital General De Tomelloso, Tomelloso · Hospital Universitario Y Politecnico La Fe, Valencia · Hospital Universitario Miguel Servet, Zaragoza
Registry updated 2026-10-26
2024-512895-36-00
A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety and Efficacy of Efruxifermin in Subjects with Compensated Cirrhosis Due to Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH)
Trial Treatment · Phase 3 · Akero Therapeutics Inc.
Hospital Universitari Vall d'Hebron, Barcelona · Clinica Universidad de Navarra, Madrid · Hospital General Universitario Gregorio Marañón, Madrid · Parc Tauli Hospital Universitari, Sabadell · Hospital Universitario Marqués de Valdecilla, Santander · University Hospital Virgen Del Rocio S.L., Sevilla · Hospital Clinico Universitario de Valencia, Valencia · Hospital Arnau de Vilanova de Valencia, Valencia
Registry updated 2026-10-23
NCT06318169
A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)
Trial Treatment · Phase 3 · Hoffmann-La Roche
Hospital Germans Trias i Pujol, Badalona · Hospital de la Santa Creu i Sant Pau, Barcelona · Hospital del Mar, Barcelona · Hospital Clinic de Barcelona, Barcelona · Hospital Universitari Vall d'Hebron, Barcelona · Hospital General Universitario Reina Sofia, Córdoba · Hospital General Universitario Gregorio Marañón, Madrid · Hospital Universitario Puerta de Hierro de Majadahonda, Majadahonda · Complexo Hospitalario Universitario de Pontevedra, Pontevedra · Hospital Universitario Marqués de Valdecilla, Santander · Complexo Hospitalario Universitario De Santiago, Santiago de Compostela · University Hospital Virgen Del Rocio S.L., Sevilla
Registry updated 2026-10-23
NCT06419374
A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH
Trial Treatment · Phase 3 · Hoffmann-La Roche
Hospital Universitario Torrecárdenas, Almería · Hospital Germans Trias i Pujol, Badalona · Hospital de la Santa Creu i Sant Pau, Barcelona · Hospital del Mar, Barcelona · Hospital Universitari Vall d'Hebron, Barcelona · Hospital Universitario Reina Sofia, Córdoba · Hospital General Universitario Gregorio Marañón, Madrid · Complexo Hospitalario Universitario de Pontevedra, Pontevedra · Hospital Universitario Marqués de Valdecilla, Santander · Complexo Hospitalario Universitario De Santiago, Santiago de Compostela · Hospital Clinico Universitario Lozano Blesa, Zaragoza
Registry updated 2026-10-23
2026-525755-82-00
A pivotal clinical study to investigate the safety and efficacy of efimosfermin compared with placebo in adult participants with compensated cirrhosis due to Metabolic dysfunction-associated steatohepatitis (MASH)
Trial Treatment · Phase 3 · Glaxosmithkline Research & Development Limited
Hospital Universitario Fundación Alcorcón, Alcorcón · Micancer Center S.L.P., Barcelona · Hospital de la Santa Creu i Sant Pau, Barcelona · Hospital Universitari Vall d'Hebron, Barcelona · Hospital Universitario Reina Sofia, Córdoba · Hospital Universitario De Leon, León · Hospital General Universitario Gregorio Marañón, Madrid · Hospital Universitario de la Princesa, Madrid · University Hospital Virgen Del Rocio S.L., Sevilla · Hospital General De Tomelloso, Tomelloso · Consorcio Hospital General Universitario de Valencia, Valencia
Registry updated 2026-10-19
2026-525757-37-00
A study to investigate safety and efficacy of efimosfermin compared with placebo in adult participants with compensated cirrhosis (stage F4 fibrosis) due to MASH (NEBULA-2)
Trial Treatment · Phase 3 · Glaxosmithkline Research & Development Limited
Hospital Universitario Fundación Alcorcón, Alcorcón · Hospital Universitari Vall d'Hebron, Barcelona · Pratia Mcc Clinic Spain S.L., Barcelona · Hospital de la Santa Creu i Sant Pau, Barcelona · Hospital Universitario Reina Sofia, Córdoba · Hospital Universitario De Leon, León · Hospital General Universitario Gregorio Marañón, Madrid · University Hospital Virgen Del Rocio S.L., Sevilla · Hospital General De Tomelloso, Tomelloso · Consorcio Hospital General Universitario de Valencia, Valencia
Registry updated 2026-10-19
NCT07683065
A Study to Estimate Secukinumab Retention Rate in Psoriasis Patients With MASLD
Research · Novartis Pharmaceuticals
Badalona · Barcelona · Madrid · Málaga · Valencia · Zaragoza
Registry updated 2026-10-16
NCT06528314
A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH
Trial Treatment · Phase 3 · Akero Therapeutics, Inc
Barcelona · Madrid · Majadahonda · Sabadell · Santander · Seville · Valencia
Registry updated 2026-10-13
NCT07165028
A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)
Trial Treatment · Phase 3 · Eli Lilly and Company
CHUAC-Complejo Hospitalario Universitario A Coruña, A Coruña · Hospital Germans Trias i Pujol, Badalona · Hospital Universitari Vall d'Hebron, Barcelona · Complejo Hospitalario Universitario de Ferrol (CHUF)- Hospital Naval, Ferrol · Hospital Infanta Elena, Huelva · Hospital Universitario La Paz, Madrid · Hospital General Universitario Gregorio Marañón, Madrid · Hospital Universitari Son Espases, Palma · CHOP - Hospital Universitario Montecelo, Pontevedra · Hospital Universitario Marqués de Valdecilla, Santander · Hospital Universitario Virgen del Rocio, Seville · Hospital Clínico de Valencia, Valencia · Hospital Universitari i Politécnic La Fe, Valencia
Registry updated 2026-10-08
NCT07221188
A Clinical Study to Investigate the Safety and Tolerability of Efimosfermin Alfa Injection in Participants With Known or Suspected F2- or F3-stage MASH
Trial Treatment · Phase 3 · GlaxoSmithKline
Complexo Hospitalario Universitario A Coruña, A Coruña · Hospital Universitario Fundación Alcorcón, Alcorcón · Hospital de la Santa Creu i Sant Pau, Barcelona · Micancer Center S.L.P., Barcelona · Hospital Universitari Vall d'Hebron, Barcelona · Hospital Quirónsalud Barcelona, Barcelona · Hospital Universitario Reina Sofia, Córdoba · Policlinica Gipuzkoa S.A., Donostia · Hospital Universitario De Leon, León · Hospital General Universitario Gregorio Marañón, Madrid · Hospital Universitario de la Princesa, Madrid · Hospital Universitario Marqués de Valdecilla, Santander · University Hospital Virgen Del Rocio S.L., Sevilla · Hospital General De Tomelloso, Tomelloso · Consorcio Hospital General Universitario de Valencia, Valencia · Hospital Clínico Universitario de Valladolid, Valladolid
Registry updated 2026-09-17
NCT06374875
Fibrosis Lessens After Metabolic Surgery
Trial Treatment · Phase 4 · The Cleveland Clinic
Hospital Clinic Barcelona, Barcelona
Registry updated 2026-07-31
NCT07684248
Butyrate or Intensive Lifestyle Modification in Type 1 Diabetes and Metabolic Dysfunction-Associated Steatotic Liver Disease
Trial Treatment · Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
Hospital Regional Universitario de Málaga, FIMABIS, Málaga
Registry updated 2026-07-06
NCT07652151
UNMASK: Unveiling the Pathobiology of Metabolic Dysfunction-Associated Steatotic Liver Disease for the Discovery of Novel Therapeutics and Biomarkers
Trial Treatment · Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Hospital Universitario Virgen del Rocío de Sevilla, Seville
Registry updated 2026-06-23
NCT07658755
Automated Passive Case-Finding for Advanced Liver Fibrosis in MASLD: The LiverSeek Programme
Research · Hospital General Universitario Gregorio Marañon
Hospital General Universitario Gregorio Marañón, Madrid
Registry updated 2026-06-22
NCT07652892
Impact of Steatotic Liver Disease Associated With Metabolic Dysfunction (MASLD) on Frailty, Cognition, and Quality of Life. A Gender-sensitive Approach Towards a Comprehensive and Equitable Perspective.
Research · Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Hospital de la Santa Creu i Sant Pau, Barcelona
Registry updated 2026-06-17
NCT07193927
Investigation of the Efficacy of a Probiotic Mixture in Moderate Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): A Mechanistic Trial
Trial Treatment · Phase 2 · AB Biotics, SA
Hospital Universitari Dr. Josep Trueta, Girona
Registry updated 2026-04-30
NCT07430501
Using Digital Twin Technology and Clinical Decision Support Systems to Improve the Early Detection, Personalised Treatment, and Long-term Monitoring of Patients Across the Full Spectrum of Metabolic-associated Fatty Liver Disease (MAFLD).
Research · Hospital Universitari Vall d'Hebron Research Institute
Vall d´Hebron Institute de Recerca (VHIR), Barcelona
Registry updated 2026-02-24
2023-505141-48-00
A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety and Efficacy of Efruxifermin in Subjects with Non-Cirrhotic Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Fibrosis
Trial Treatment · Phase 3 · Akero Therapeutics Inc.
Hospital Universitari Vall d'Hebron, Barcelona · Hospital General Universitario Gregorio Marañón, Madrid · Clinica Universidad de Navarra, Madrid · Hospital Universitario Puerta de Hierro de Majadahonda, Majadahonda · Parc Tauli Hospital Universitari, Sabadell · Hospital Universitario Marqués de Valdecilla, Santander · University Hospital Virgen Del Rocio S.L., Sevilla · Hospital Universitario Y Politecnico La Fe, Valencia · Hospital Arnau de Vilanova de Valencia, Valencia
Registry updated 2026-01-22
NCT06599918
Study of the Efficacy and Safety of Nicotinamide in Patients With Liver Fibrosis (NICOFIB)
Trial Treatment · Phase 2 · Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Hospital de la Santa Creu i Sant Pau, Barcelona
Registry updated 2025-11-18
NCT07188220
Patients' Perspectives on Metabolic Dysfunction-associated Steatohepatitis: a Qualitative Study
Research · Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
IR Sant Pau, Barcelona
Registry updated 2025-09-23

All Fatty liver disease (MASLD/MASH) trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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