Frontotemporal dementia: open trials in United Kingdom

• NCT06297590

  A First-In-Human Study of LY3954068 in Participants With Early Symptomatic Alzheimer's Disease

  Trial Treatment · Phase 1 · Eli Lilly and Company

  National Hospital for Neurology and Neurosurgery (UCLH), London · Royal Hallamshire Hospital, Sheffield · University Hospital Southampton, Southampton

  Registry updated 2026-10-29

• NCT06064890

  A Study to Evaluate the Safety and Effect of AVB-101, a Gene Therapy Product, in Subjects With a Genetic Sub-type of Frontotemporal Dementia (FTD-GRN)

  Trial Treatment · Phase 1/2 · AviadoBio Ltd

  Cambridge University Hospitals NHS Foundation Trust, Cambridge · University Hospital of Wales, Cardiff · University College London Hospitals, London

  Registry updated 2026-08-13

• NCT05163288

  A Pivotal Study of N-Acetyl-L-Leucine on Niemann-Pick Disease Type C

  Trial Treatment · Phase 3 · IntraBio Inc

  Royal Free London NHS Foundation Trust, London · Great Ormond Street Hospital, London · Royal Manchester Children's Hospital, Manchester

  Registry updated 2026-04-03

• NCT05885295

  The Imperial Comprehensive Cognitive Assessment in Cerebrovascular Disease (IC3)

  Research · Imperial College London

  Imperial College London, London

  Registry updated 2023-06-01

All Frontotemporal dementia trials and the map

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