Gastric and oesophageal cancer trials in Belgium

In Belgium 33 Also abroad 1285

33 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 14 November 2026. Ask the study team whether a trial fits you.

Phase 3Taking people
A clinical trial of belzutifan and other treatments in people with solid tumors or von Hippel-Lindau (VHL)-related tumors (MK-6482-043)
Where
Leuven
Age
18 years and over
People
134 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to join2025-524160-38-00
Phase 3Taking people
A Study of ASP2138 Together With Chemotherapy and Pembrolizumab in Adults With Gastric Cancer
Where
Anderlecht, Bonheiden, Charleroi, Edegem, Gent, Liège, Sint-Lambrechts-Woluwe
Age
18 years and over
People
570 worldwide
Run by
Astellas Pharma Global Development, Inc.
See details and how to joinNCT07673887 · EU 2025-524557-14-00
Phase 2/3Taking people
Multicenter Validation Trial of [18F]AlF-FAPI-74 for PET Imaging of Cancer-associated Fibroblasts Through Fibroblast Activation Protein Inhibitors (FAPI) in Different Tumor Types
Where
Edegem, Ghent, Leuven
Age
18 years and over
People
109
Run by
KU Leuven
See details and how to joinNCT06782412
Phase 1/2Taking people
Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread
Where
Brussels, Edegem, Leuven, Libramont-Chevigny, Liège, Namur
Age
18 years and over
People
910 worldwide
Run by
Boehringer Ingelheim
See details and how to joinNCT06324357
Phase 3Taking people
A Study of Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With Gastric Cancer
Where
Anderlecht, Bonheiden, Edegem, Gent, Leuven, Liège, Sint-Lambrechts-Woluwe
Age
18 years and over
People
500 worldwide
Run by
Astellas Pharma Global Development, Inc.
See details and how to joinNCT06901531 · EU 2024-519773-19-00
Phase 1/2Taking people
A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors
Where
Anderlecht, Gent, Namur, Sint-Lambrechts-Woluwe
Age
18 years and over
People
560 worldwide
Run by
Genmab
See details and how to joinNCT03526835 · EU 2024-513627-16-01
Phase 1/2Taking people
EIK1005-002: A Clinical Research Study Evaluating EIK1005, a Werner Helicase Inhibitor, as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors Including Microsatellite Instability High (MSI-H) Tumors
Where
Brussels
Age
18 years and over
People
160 worldwide
Run by
Eikon Therapeutics
See details and how to joinNCT07262619 · EU 2026-525248-13-00
Phase 2Taking people
A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
Where
Brussels, Edegem, Ghent, Jette, Leuven
Age
18 years and over
People
740 worldwide
Run by
Daiichi Sankyo
See details and how to joinNCT06172478 · EU 2023-507641-29-00
Phase 1/2Taking people
A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02)
Where
Charleroi, Gent, Leuven, Liège, Sint-Lambrechts-Woluwe
Age
18 years and over
People
680 worldwide
Run by
Daiichi Sankyo
See details and how to joinNCT06330064 · EU 2023-509632-26-00
Phase 3Taking people
A Study of Ifinatamab Deruxtecan in Subjects With Pretreated Advanced or Metastatic Esophageal Squamous Cell Carcinoma (ESCC) (IDeate-Esophageal01)
Where
Brussels, Edegem, Ghent, Leuven, Liège
Age
18 years and over
People
510 worldwide
Run by
Daiichi Sankyo
See details and how to joinNCT06644781 · EU 2023-509630-19-00
Phase 1Taking people
A phase I study of [177Lu]Lu-DWJ155 and [68Ga]Ga-DWJ155 in patients with solid tumors
Where
Sint-Lambrechts-Woluwe
Age
18 years and over
People
64 worldwide
Run by
Novartis Pharma AG
See details and how to join2024-518348-19-00
Phase 3Taking people
A Phase Ⅲ Study of Rilvegostomig in Combination With Fluoropyrimidine and Trastuzumab Deruxtecan as the First-line Treatment for HER2-positive Gastric Cancer
Where
Edegem, Gent, Leuven, Liège
Age
18 years and over
People
840 worldwide
Run by
AstraZeneca
See details and how to joinNCT06764875 · EU 2024-512583-57-00
Phase 3Taking people
Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Expressing Claudin18.2
Where
Edegem, Gent, Leuven, Sint-Lambrechts-Woluwe
Age
18 years and over
People
2,130 worldwide
Run by
AstraZeneca
See details and how to joinNCT07431281 · EU 2024-519787-40-00
Phase 1/2Taking people
A Clinical Study to Test if an Investigational Treatment Called BNT326 is Safe and Potentially Beneficial When Used Alone or in Combination With Other Investigational Treatments Such as BNT327, for People With Advanced Malignant Tumors
Where
Anderlecht, Ghent, Liège, Wilrijk
Age
18 years and over
People
1,438 worldwide
Run by
BioNTech SE
See details and how to joinNCT07070232 · EU 2024-517261-16-00
Phase 1Taking people
A Phase 1 Study to Evaluate the Safety, Tolerability, and Preliminary Efficacy of Denikitug (GS-1811), an Afucosylated Anti-CCR8 Monoclonal Antibody, as Monotherapy and in Combination With an Anti–PD-1 Monoclonal Antibody in Adults With Advanced Solid Tumors
Where
Edegem, Hasselt, Leuven
Age
18 years and over
People
93 worldwide
Run by
Gilead Sciences Inc.
See details and how to joinNCT05007782 · EU 2022-501684-40-00
Phase 2Taking people
OBSiDiAN in a Stapled Circular Esophagogastric Anastomosis After Ivor Lewis Esophagectomy
Where
Ghent
Age
18 years to 75 years
People
90
Run by
University Hospital, Ghent
See details and how to joinNCT05713955
Phase 3Taking people
Trial of Trastuzumab Deruxtecan (Enhertu®) Plus Chemotherapy Plus or Minus Pembrolizumab versus Chemotherapy Plus Trastuzumab Plus or Minus Pembrolizumab in First-line Metastatic HER2-positive Gastric or GEJ Cancer
Where
Anderlecht, Brugge, Leuven, Liège, Namur, Sint-Lambrechts-Woluwe
Age
18 years and over
People
228 worldwide
Run by
Daiichi Sankyo Inc.
See details and how to join2024-513122-27-00
No phaseTaking people
The Prevalence and the Pathophysiological Role of Non-Helicobacter Pylori Helicobacter Spp. in Well-defined Gastric Diseases and (Pre-) Malignancies
Where
Edegem, Ghent, Kortrijk
Age
18 years and over
People
150
Run by
Universiteit Antwerpen
See details and how to joinNCT07770126
Phase 3Taking people
Study of TDXd, Chemotherapy, Pembrolizumab, and Trastuzumab in First-Line Metastatic HER2-Positive Gastric or Gastroesophageal Junction Cancer
Where
Anderlecht, Bruges, Brussels, Leuven, Liège, Namur
Age
18 years and over
People
726 worldwide
Run by
Daiichi Sankyo
See details and how to joinNCT06731478
Phase 1Taking people
A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors
Where
Anderlecht
Age
18 years and over
People
714 worldwide
Run by
Seagen, a wholly owned subsidiary of Pfizer
See details and how to joinNCT05208762 · EU 2023-506604-18-00
No phaseTaking people
Liquid Biopsies in Esophageal Cancer
Where
Antwerp, Ghent, Leuven, Roeselare
Age
18 years and over
People
248
Run by
Universitaire Ziekenhuizen KU Leuven
See details and how to joinNCT05704530
Phase 1/2Taking people
Beamion BCGC-1: A study to find a suitable dose of zongertinib used alone and in combination with other treatments to test whether it helps people with different types of HER2+ cancer that has spread
Where
Edegem, Leuven, Libramont-Chevigny, Namur, Sint-Lambrechts-Woluwe
Age
18 years and over
People
181 worldwide
Run by
Boehringer Ingelheim International GmbH
See details and how to join2023-509566-38-00
No phaseNot yet taking people in Belgium
A Study of Barrett's Esophagus Patients: Optimization of a Risk Model to Better Predict the Development of Cancer Recurrence and the Effect of Risk Profile Disclosure on Patient Quality of Life and Fear of Cancer
Where
Edegem, Ghent, Roeselare, Wilrijk
Age
18 years and over
People
266 worldwide
Run by
University Hospital, Antwerp
See details and how to joinNCT07455422
No phaseTaking people
The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study
Where
Brussels
Age
18 years and over
People
8,000 worldwide
Run by
UMC Utrecht
See details and how to joinNCT04075305
No phaseTaking people
A Study of Barrett's Esophagus Patients to Investigate Quality of Life and Fear of Cancer, and Optimize a Risk Model Based on Biomarkers and New Technologies to Better Predict the Development of Cancer
Where
Edegem, Ghent, Roeselare, Wilrijk
Age
18 years and over
People
50 worldwide
Run by
University Hospital, Antwerp
See details and how to joinNCT06523374