Gastric and oesophageal cancer trials in Chile

12 trials · From ClinicalTrials.gov, checked 15 November 2026. Ask the study team whether a trial fits you.

• Phase 1/2Taking people
  Substudy 06C: A Study of Investigational Agents With Pembrolizumab (MK-3475) and Chemotherapy in Participants With First-Line Locally Advanced Unresectable/Metastatic Gastroesophageal Adenocarcinoma (MK-3475-06C/KEYMAKER-U06)

  Where

  Antofagasta, Port Montt, Santiago, Talca

  Age

  18 years and over

  People

  160 worldwide

  Run by

  Merck Sharp & Dohme LLC

  See details and how to joinNCT06469944 · EU 2023-509307-33-00
• Phase 1/2Taking people
  Substudy 06E: Umbrella Study of Combination Therapies in Esophageal Cancer (MK-3475-06E/KEYMAKER-U06)

  Where

  Antofagasta, Port Montt, Santiago

  Age

  18 years and over

  People

  298 worldwide

  Run by

  Merck Sharp & Dohme LLC

  See details and how to joinNCT06780111 · EU 2024-514273-22-00
• Phase 1/2Taking people
  A Clinical Trial of Ifinatamab Deruxtecan in People With Advanced Esophageal Cancer (MK-3475-06F)

  Where

  Santiago

  Age

  18 years and over

  People

  60 worldwide

  Run by

  Merck Sharp & Dohme LLC

  See details and how to joinNCT07405151 · EU 2026-525213-31-00
• Phase 3Taking people
  A Study of Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With Gastric Cancer

  Where

  Las Condes, Santiago

  Age

  18 years and over

  People

  500 worldwide

  Run by

  Astellas Pharma Global Development, Inc.

  See details and how to joinNCT06901531 · EU 2024-519773-19-00
• Phase 2/3Not yet taking people in Chile
  A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Nivolumab in Combination With Chemotherapy in Participants With Previously Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma (ROSETTA Gastric-204)

  Where

  Santiago

  Age

  18 years and over

  People

  690 worldwide

  Run by

  Bristol-Myers Squibb

  See details and how to joinNCT07221149 · EU 2025-523263-37-00
• Phase 1/2Taking people
  A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02)

  Where

  Concepción, La Serena, Santiago, Temuco

  Age

  18 years and over

  People

  680 worldwide

  Run by

  Daiichi Sankyo

  See details and how to joinNCT06330064 · EU 2023-509632-26-00
• Phase 3Taking people
  A Phase Ⅲ Study of Rilvegostomig in Combination With Fluoropyrimidine and Trastuzumab Deruxtecan as the First-line Treatment for HER2-positive Gastric Cancer

  Where

  Port Montt, Rancagua, Santiago, Temuco, Viña del Mar

  Age

  18 years and over

  People

  840 worldwide

  Run by

  AstraZeneca

  See details and how to joinNCT06764875 · EU 2024-512583-57-00
• Phase 1/2Taking people
  A Study to Evaluate Investigational Agents With or Without Pembrolizumab (MK-3475) in Participants With Advanced Esophageal Cancer Previously Exposed to Programmed Cell Death 1 Protein (PD-1)/ Programmed Cell Death Ligand 1 (PD-L1) Treatment (MK-3475-06B)

  Where

  Santiago

  Age

  18 years and over

  People

  230 worldwide

  Run by

  Merck Sharp & Dohme LLC

  See details and how to joinNCT05319730 · EU 2023-505189-26-00
• Phase 1/2Taking people
  Substudy 06D: Combination Therapies in Second Line (2L) Gastroesophageal Adenocarcinoma (MK-3475-06D/Keymaker-U06)

  Where

  Antofagasta, Port Montt, Santiago, Talca

  Age

  18 years and over

  People

  210 worldwide

  Run by

  Merck Sharp & Dohme LLC

  See details and how to joinNCT06445972 · EU 2023-509306-29-00
• Phase 3Taking people
  Study of TDXd, Chemotherapy, Pembrolizumab, and Trastuzumab in First-Line Metastatic HER2-Positive Gastric or Gastroesophageal Junction Cancer

  Where

  Concepción, Rancagua, Region Del Maule, Santiago

  Age

  18 years and over

  People

  726 worldwide

  Run by

  Daiichi Sankyo

  See details and how to joinNCT06731478
• Phase 3Taking people
  A Phase Ⅲ Clinical Study of HLX22 in Combination With Trastuzumab and Chemotherapy for the Treatment of Gastroesophageal Junction and Gastric Cancer

  Where

  Santiago

  Age

  18 years and over

  People

  550 worldwide

  Run by

  Shanghai Henlius Biotech

  See details and how to joinNCT06532006 · EU 2024-516633-12-00
• No phaseNot yet taking people in Chile
  Screening of Gastric Cancer Via Breath Volatile Organic Compounds by Hybrid Sensing Approach

  Where

  Santiago

  Age

  18 years and over

  People

  5,000 worldwide

  Run by

  University of Latvia

  See details and how to joinNCT04022109