Glioblastoma: open trials in Norway

• NCT03548571

  Study to evaluate the therapeutic effect of a cell based immune therapy targeting cancer stem cells i the malignant brain tumor glioblastoma.

  Trial Treatment · Phase 2/3 · Oslo University Hospital HF

  Oslo University Hospital HF, Oslo

  Registry updated 2026-10-20

• 2023-506998-35-00

  Phase III trial of lomustine/temozolomide (TMZ) combination therapy vs. standard TMZ therapy for newly diagnosed MGMT promoter methylated glioblastoma (IDHwt) patients +/- tumor treating fields (Optune)

  Trial Treatment · Phase 3 · Vaestra Goetalandsregionen

  Helse Bergen HF, Bergen · Sykehuset Ostfold HF, Graalum · Sorlandet Sykehus HF, Kristiansand S · Oslo University Hospital HF, Oslo · Helse Stavanger HF, Stavanger · Universitetssykehuset Nord-Norge HF, Tromsoe · St. Olavs hospital HF, Trondheim

  Registry updated 2026-08-27

• NCT03643549

  Bortezomib and Temozolomide in Recurrent Grade-4 Glioma Unmethylated MGMT Promoter (BORTEM-17)

  Trial Treatment · Phase 1/2 · Haukeland University Hospital

  Helse Bergen HF, Bergen · Oslo University Hospital HF, Oslo · Universitetssykehuset Nord-Norge HF, Tromsoe · St. Olavs hospital HF, Trondheim

  Registry updated 2026-08-04

• NCT05904119

  Lomustine With and Without Reirradiation for First Progression of Glioblastoma: a Randomized Phase III Study

  Trial Treatment · Phase 3 · European Organisation for Research and Treatment of Cancer - EORTC

  Oslo University Hospital HF, Oslo · St. Olavs hospital HF, Trondheim

  Registry updated 2026-06-08

• 2026-525543-32-00

  A study to investigate how a single dose of the drug melflufen reaches brain tumor tissue, and how it affects the tumour, in patients who are already scheduled for surgery for a returning glioblastoma

  Trial Treatment · Phase 1 · Oncopeptides AB

  Oslo Universitetssykehus HF, Oslo

  Registry updated 2026-05-15

• 2023-504696-24-00

  The ALPINE trial: a phase 1-2 study of intra-arterial [177Lu]Lu-PSMA-I&T for progressive or recurrent intracranial adult type diffuse glioma

  Trial Treatment · Phase 1/2 · Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)

  St. Olavs hospital HF, Trondheim

  Registry updated 2026-05-13

• NCT06419946

  Lomustine in Addition to Standard of Care in Patients With MGMT Methylated Glioblastoma

  Trial Treatment · Phase 3 · Vastra Gotaland Region

  Haukeland University Hospital, Bergen · Sorlandet Sykehus, Kristiansand · Oslo University Hospital, Oslo · Stavanger University Hospital, Stavanger · St Olavs Hospital, Trondheim

  Registry updated 2026-04-13

• NCT05043701

  Individualized Systems Medicine strategy to target cancer stem cells in patients with recurrent Glioblastoma (ISM-GBM)

  Trial Treatment · Phase 1 · Oslo University Hospital HF

  Oslo University Hospital HF, Oslo

  Registry updated 2026-02-23

All Glioblastoma trials and the map

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