Head and neck cancer trials in Spain
52 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 13 November 2026. Ask the study team whether a trial fits you.
- Phase 1Taking peopleEvaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors
- Where
- Barcelona, Madrid, Piqueras, Seville
- Age
- 18 years and over
- People
- 540 worldwide
- Run by
- SystImmune Inc.
See details and how to joinNCT05983432 - No phaseTaking peoplePhotobiomodulation Therapy Plus M-health in Head and Neck Cancer Patients: LAXER Study
- Where
- Granada
- Age
- 18 years and over
- People
- 60
- Run by
- Universidad de Granada
See details and how to joinNCT05106608 - No phaseTaking peopleORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation
- Where
- A Coruña, Barcelona, Girona, Las Palmas de Gran Canaria, Madrid, Málaga, Sabadell, Santiago de Compostela, Valencia
- Age
- 18 years and over
- People
- 2,285 worldwide
- Run by
- Guardant Health, Inc.
See details and how to joinNCT05059444 - Phase 1/2Taking peopleFirst in Human Study of TUB-030 in Patients With Advanced Solid Tumors
- Where
- Barcelona, Madrid
- Age
- 18 years and over
- People
- 250 worldwide
- Run by
- Gilead Sciences
See details and how to joinNCT06657222 · EU 2025-522517-35-00 - Phase 1/2Taking peopleSafety and Efficacy of VB10.16 and Pembrolizumab in Patients With Head-Neck Squamous Cell Carcinoma
- Where
- Barcelona, L'Hospitalet de Llobregat, Madrid, Málaga, Pozuelo de Alarcón
- Age
- 18 years and over
- People
- 110 worldwide
- Run by
- Nykode Therapeutics ASA
See details and how to joinNCT06016920 · EU 2022-503055-26-00 - Phase 1/2Taking peopleA Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors
- Where
- Badalona, Barcelona, Madrid, Málaga, Pamplona
- Age
- 18 years and over
- People
- 1,109 worldwide
- Run by
- Bristol-Myers Squibb
See details and how to joinNCT04895709 - Phase 1/2Taking peopleA Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors
- Where
- Barcelona, Madrid, Valencia
- Age
- 18 years and over
- People
- 366 worldwide
- Run by
- Marengo Therapeutics, Inc.
See details and how to joinNCT05592626 · EU 2023-505334-10-01 - Phase 2Taking peopleCLEAR (Cervical Lymphatic Exclusion in Adjuvant Radiation)
- Where
- L'Hospitalet de Llobregat
- Age
- 18 years and over
- People
- 101
- Run by
- Institut Català d'Oncologia
See details and how to joinNCT07755449 - No phaseNot yet taking people in SpainRetrospective Observational Study of Oral Complications and Quality of Life in Head and Neck Cancer Patients Treated With Radiotherapy or Chemoradiotherapy.
- Where
- Madrid
- Age
- 18 years and over
- People
- 60
- Run by
- Mucosa Innovations, S.L.
See details and how to joinNCT07739771 - Phase 1Taking peopleA Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors
- Where
- Barcelona, L'Hospitalet de Llobregat, Madrid
- Age
- 18 years and over
- People
- 714 worldwide
- Run by
- Seagen, a wholly owned subsidiary of Pfizer
See details and how to joinNCT05208762 · EU 2023-506604-18-00 - Phase 1/2Taking peopleFirst-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors
- Where
- Barcelona, Logroño, Madrid, Pozuelo de Alarcón, Reus, Sevilla
- Age
- 18 years and over
- People
- 880 worldwide
- Run by
- Eli Lilly and Company
See details and how to joinNCT05768139 · EU 2023-504807-94-00 - Phase 1Taking peopleA Study of Sigvotatug Vedotin in Advanced Solid Tumors
- Where
- Barcelona, Elche, Jerez de la Frontera, Madrid, Málaga, Santander
- Age
- 18 years and over
- People
- 1,006 worldwide
- Run by
- Seagen, a wholly owned subsidiary of Pfizer
See details and how to joinNCT04389632 · EU 2023-508469-34-00 - Phase 1Taking peopleStudy With ABBV-CLS-484 in Participants With Locally Advanced or Metastatic Tumors
- Where
- L'Hospitalet de Llobregat, Madrid
- Age
- 18 years and over
- People
- 248 worldwide
- Run by
- Calico Life Sciences LLC
See details and how to joinNCT04777994 · EU 2023-507568-38-00 - Phase 2Taking peopleStudy of Cetuximab Plus/Minus Weekly Paclitaxel After Progression To First-Line Pembrolizumab Plus Platinum-5FU in Subjects With Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck.
- Where
- A Coruna, Badalona, Granada, L'Hospitalet de Llobregat, Lugo, Madrid, Málaga, Pamplona, Salamanca, San Cristóbal de La Laguna, Santander, Santiago de Compostela, Sevilla, Toledo
- Age
- 18 years and over
- People
- 65
- Run by
- Grupo Español de Tratamiento de Tumores de Cabeza y Cuello
See details and how to joinNCT06856213 · EU 2024-514953-31-00 - Phase 3Taking peoplePembrolizumab and Radiotherapy for Oligometastatic Head and Neck Cancer
- Where
- Badalona, Barakaldo, Barcelona, Las Palmas De Gran Canaria, L'Hospitalet de Llobregat, Madrid
- Age
- 18 years and over
- People
- 200 worldwide
- Run by
- European Organisation for Research and Treatment of Cancer - EORTC
See details and how to joinNCT05815927 · EU 2023-504478-39-00 - Phase 1/2Taking peopleAfatinib in Patients With Fanconi Anemia (FA) and Advanced Head and Neck Squamous Cell Carcinoma (HNSCC)
- Where
- Barcelona
- Age
- 18 years and over
- People
- 25 worldwide
- Run by
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
See details and how to joinNCT06648096 · EU 2024-511477-29-00 - Phase 3Taking peopleA Study of Dostarlimab vs Placebo After Chemoradiation in Adult Participants With Locally Advanced Unresected Head and Neck Squamous Cell Carcinoma
- Where
- Barakaldo, Barcelona, Cartagena, Jerez de la Frontera, L'Hospitalet de Llobregat, Lugo, Madrid, Pamplona, Salamanca, Santander, Zaragoza
- Age
- 18 years and over
- People
- 864 worldwide
- Run by
- GlaxoSmithKline
See details and how to joinNCT06256588 · EU 2023-508613-17-00 - Phase 3Taking peopleStudy Comparing Ivonescimab Alone or Ivonescimab in Combination With Ligufalimab Versus Pembrolizumab for the Treatment of SCCHN
- Where
- Barcelona, BARCELONE, Girona, Granada, Madrid, Málaga, Salamanca, Zaragoza
- Age
- 18 years to 80 years
- People
- 780 worldwide
- Run by
- Groupe Oncologie Radiotherapie Tete et Cou
See details and how to joinNCT07264075 · EU 2025-522996-27-00 - No phaseNot yet taking people in SpainAI-Assisted Endoscopy for Upper Aerodigestive Tract Lesions
- Where
- Barcelona
- Age
- 18 years and over
- People
- 283 worldwide
- Run by
- Istituto Italiano di Tecnologia
See details and how to joinNCT07596355 - Phase 1Taking peopleA Study to Evaluate the Safety and Tolerability of TOS-358 in Women With HR+ HER2- Breast Cancer
- Where
- Barcelona, Madrid, Pamplona, Pozuelo de Alarcón, Valencia
- Age
- 18 years and over
- People
- 241 worldwide
- Run by
- Totus Medicines
See details and how to joinNCT05683418 · EU 2023-505346-26-01 - No phaseTaking peopleEffect of a Novel Topical Composition on the Incidence of Severe Oral Mucositis in Head & Neck Cancer Radiated Patients and Quality of Life Assessed by PROMs.
- Where
- Madrid
- Age
- 18 years and over
- People
- 63
- Run by
- Mucosa Innovations, S.L.
See details and how to joinNCT05635929 - Phase 3Taking peopleA Study of Ficlatuzumab in Combination With Cetuximab in Participants With Recurrent or Metastatic (R/M) HPV Negative Head and Neck Squamous Cell Carcinoma
- Where
- Badalona, Barcelona, Castello De La Plana, Elche, Jerez de la Frontera, L'Hospitalet de Llobregat, Madrid, Málaga, Santander, Torrejón de Ardoz
- Age
- 18 years and over
- People
- 410 worldwide
- Run by
- AVEO Pharmaceuticals, Inc.
See details and how to joinNCT06064877 · EU 2023-505606-42-00 - Phase 1/2Taking peoplePhase 1/2 Study to Evaluate TH9619 in the Treatment of Advanced Solid Tumors
- Where
- Barcelona, Madrid
- Age
- 18 years and over
- People
- 43 worldwide
- Run by
- One-carbon Therapeutics AB
See details and how to joinNCT07151040 · EU 2024-519639-40-00 - No phaseNot yet taking people in SpainNeutrophil Biomarker Test for Predicting Clinical Benefit From Immunotherapy Based on Flow Cytometry Analysis
- Where
- Seville
- Age
- 18 years and over
- People
- 600 worldwide
- Run by
- OncoHost Ltd.
See details and how to joinNCT07246759 - Phase 1/2Taking peoplePhase 1/2 Clinical Trial of CP-506 (HAP) in Monotherapy or With Carboplatin or ICI
- Where
- Barcelona
- Age
- 18 years and over
- People
- 126 worldwide
- Run by
- Maastricht University Medical Center
See details and how to joinNCT04954599