Haemophilia: open trials in Canada

19 open trials have a site in Canada. Registry data; only the trial team decides who can take part.

NCT05987449
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of NXT007 in Persons With Severe or Moderate Hemophilia A
Trial Treatment · Phase 1/2 · Hoffmann-La Roche
Hamilton Health Sciences Corporation, Hamilton · British Columbia Children's Hospital, Vancouver
Registry updated 2026-11-05
NCT07416604
A Clinical Study to Evaluate the Effects of NXT007 Compared to Emicizumab Prophylaxis in People With Hemophilia A
Trial Treatment · Phase 3 · Hoffmann-La Roche
London Health Sciences Centre, London
Registry updated 2026-11-03
NCT07830732
A Research Study Investigating Denecimig (Mim8) in Adults With Acquired Haemophilia A
Trial Treatment · Phase 3 · Novo Nordisk A/S
McMaster University, Hamilton · St. Michael's Hospital, Toronto · St Pauls Hospital, Vancouver
Registry updated 2026-10-28
NCT07285460
A Study to Investigate the Efficacy and Safety of Fitusiran Prophylaxis in Male Participants Aged 1 to Less Than 12 Years With Hemophilia A or B
Trial Treatment · Phase 3 · Sanofi
Hamilton · Montreal · Toronto
Registry updated 2026-10-27
NCT05145127
Open-Label Extension Study of Marstacimab in Hemophilia Participants With or Without Inhibitors
Trial Treatment · Phase 3 · Pfizer
Stollery Children'S Hospital, Edmonton · Hamilton Health Sciences - McMaster University Medical Centre, Hamilton
Registry updated 2026-10-26
NCT07088458
An Observational Study to Learn More About How Well Damoctocog Alfa Pegol Works in Previously Treated Children With Hemophilia A
Research · Bayer
Many Locations, Many Locations
Registry updated 2026-10-26
NCT06379789
A Study to Investigate the Safety and Effectiveness of a Coagulation Factor IX Gene Insertion Therapy (REGV131-LNP1265) in Pediatric, Adolescent and Adult Participants With Hemophilia B
Trial Treatment · Phase 1/2 · Regeneron Pharmaceuticals
University of Alberta Hospital, Edmonton · McMaster University Medical Centre, Hamilton Health Sciences, Hamilton · Mcgill University Health Center (MUHC), Montreal
Registry updated 2026-10-21
NCT06941870
Efanesoctocog Alfa Prophylaxis in Patients With Hemophilia A With Synovial Hypertrophy
Trial Treatment · Phase 4 · Sanofi
Hamilton · Hamilton
Registry updated 2026-10-15
NCT05611801
A Clinical Trial of Study Medicine (Marstacimab) in Pediatric Patients With Hemophilia A or Hemophilia B
Trial Treatment · Phase 3 · Pfizer
Stollery Children'S Hospital, Edmonton · Hamilton Health Sciences - McMaster University/McMaster Children's Hospital, Hamilton
Registry updated 2026-10-14
NCT07452575
3D Ultrasound in Hemophilic Ankles
Trial Treatment · The Hospital for Sick Children
The Hospital for Sick Children, Toronto
Registry updated 2026-10-14
NCT05568719
Safety and Effectiveness of Giroctocogene Fitelparvovec or Fidanacogene Elaparvovec in Patients With Hemophilia A or B Respectively
Trial Treatment · Phase 3 · Pfizer
Unity Health Toronto, St. Michael's Hospital, Toronto
Registry updated 2026-10-07
NCT06003387
Efficacy and Safety of CSL222 (Etranacogene Dezaparvovec) Gene Therapy in Adults With Hemophilia B With Pretreatment Adeno-associated Virus Serotype 5 (AAV5) Neutralizing Antibodies (Nabs)
Trial Treatment · Phase 3 · CSL Behring
McMaster University - Hamilton, Hamilton
Registry updated 2026-08-27
NCT04278404
Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
Research · Duke University
CHU Sainte-Justine, Montreal · The Hospital for Sick Children, Toronto
Registry updated 2026-08-21
NCT06349473
A Study of Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SR604 in Two Participants Groups (Part A: Healthy Participants, and Part B: Participants With Hemophilia A or Hemophilia B or Factor VII Deficiency)
Trial Treatment · Phase 1 · Equilibra Bioscience LLC
McMaster University Medical Centre, Hamilton Health Sciences, Hamilton
Registry updated 2026-07-02
NCT03745924
A Study Following Males With Haemophilia B on Prophylaxis With Refixia/REBINYN
Research · Novo Nordisk A/S
University of Calgary Cumming School of Medicine, Calgary · Univ of Alberta Hospital Res, Edmonton · Hamltn Hth Sci/McMstr Child Hosp, Hamilton · Hamilton Health Sciences Corp, Ontario, Hamilton · Health Science Centre, St. John's · The Hospital for Sick Children, Toronto · CancerCare Manitoba, Winnipeg
Registry updated 2026-06-12
NCT03695978
Efficacy, Safety & Utilisation of Nuwiq, Octanate and Wilate in Previously Untreated & Minimally Treated Haemophilia A Patients
Research · Octapharma
Department of Hematology Research Research Transition Facility, Edmonton · McMaster University, Division of Pediatric Hematology/Oncology Room 3N27, Hamilton
Registry updated 2026-06-02
NCT02979119
The European Paediatric Network for Haemophilia Management ( PedNet Registry)
Research · PedNet Haemophilia Research Foundation
Division of Hematology/Oncology Hôpital St Justine, Montreal · Division of Haematology/Oncology Hospital for Sick Children, Toronto
Registry updated 2025-09-16
NCT03549858
Patient Reported Outcomes Burdens and Experiences - Phase 3
Research · McMaster University
McMaster University, Hamilton
Registry updated 2025-08-22
NCT03327779
World Bleeding Disorders Registry
Research · World Federation of Hemophilia
World Federation of Hemophilia, Montreal
Registry updated 2023-08-14

All Haemophilia trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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