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Haemophilia: open trials in United States

42 open trials have a site in United States. Registry data; only the trial team decides who can take part.

  • NCT05987449

    A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of NXT007 in Persons With Severe or Moderate Hemophilia A

    Trial Treatment · Phase 1/2 · Hoffmann-La Roche

    Indiana Hemophilia & Thrombosis Center, Indianapolis · University of Iowa Hospitals and Clnics Dept of Pediatrics, Iowa City · UC Davis Cancer Center, Sacramento · Georgetown Uni Medical Center, Washington D.C.

    Registry updated 2026-11-05

  • NCT07416604

    A Clinical Study to Evaluate the Effects of NXT007 Compared to Emicizumab Prophylaxis in People With Hemophilia A

    Trial Treatment · Phase 3 · Hoffmann-La Roche

    University of Michigan - 1500 E Medical Center Dr, Ann Arbor · University of Colorado Hemophilia and Thrombosis Center, Aurora · Innovative Hematology, Inc., Indianapolis · University of Iowa Hospitals and Clinics, Iowa City · University of Miami Hospital, Miami · M Health Fairview - Pediatric Specialty Clinic-Discovery, Minneapolis · Center for Inherited Blood Disorders, Orange · The University of Texas Health Science Center at San Antonio, San Antonio · Washington Center for Bleeding Disorders, Seattle · St Joseph's Children's Hospital of Tampa, Tampa

    Registry updated 2026-11-03

  • NCT07830732

    A Research Study Investigating Denecimig (Mim8) in Adults With Acquired Haemophilia A

    Trial Treatment · Phase 3 · Novo Nordisk A/S

    University of Vermont Med Ctr, Burlington · University of North Carolina, Chapel Hill · University of Virginia, Charlottesville · UT Southwestern, Dallas · Duke University_Durham, Durham · Penn State MS Hershey Med Ctr, Hershey · Univ Texas HSC-Houston, Houston · University Of Iowa_Iowa City, Iowa City · Tulane University School of Medicine, Metairie · University of Minnesota, Minneapolis · University of Oklahoma Health, Oklahoma City · Univ of Pennsylvania Hospital, Philadelphia · Virginia Cwealth Univ Richmond, Richmond · Mayo Clinic, Rochester · University Of Utah Health, Salt Lake City · UT Health San Antonio, San Antonio · Washington Ctr Bleed Disorder, Seattle · Washington University, St Louis

    Registry updated 2026-10-28

  • NCT07285460

    A Study to Investigate the Efficacy and Safety of Fitusiran Prophylaxis in Male Participants Aged 1 to Less Than 12 Years With Hemophilia A or B

    Trial Treatment · Phase 3 · Sanofi

    University of Michigan Health System - Ann Arbor- Site Number : 8400003, Ann Arbor · University of Texas - Southwestern Medical Center- Site Number : 8400015, Dallas · Hackensack Meridian Health - Hackensack University Medical Center- Site Number : 8400008, Hackensack · Cure 4 The Kids Foundation- Site Number : 8400001, Las Vegas · The Luskin Orthopaedic Institute for Children- Site Number : 8400013, Los Angeles · Children's Hospital Los Angeles- Site Number : 8400002, Los Angeles · The Center for Inherited Blood Disorders- Site Number : 8400009, Orange · UCLA Medical Center - Harbor- Site Number : 8400011, Torrance

    Registry updated 2026-10-27

  • NCT05145127

    Open-Label Extension Study of Marstacimab in Hemophilia Participants With or Without Inhibitors

    Trial Treatment · Phase 3 · Pfizer

    University of Iowa, Iowa City · Northwell Health HTC, New Hyde Park · The Feinstein Institutes for Medical Research, Philadelphia · Washington Institute for Coagulation d/b/a WACBD, Seattle

    Registry updated 2026-10-26

  • NCT07088458

    An Observational Study to Learn More About How Well Damoctocog Alfa Pegol Works in Previously Treated Children With Hemophilia A

    Research · Bayer

    Loma Linda University Health, Loma Linda · Rutgers, The State University, New Brunswick

    Registry updated 2026-10-26

  • NCT07416526

    A Clinical Study to Evaluate the Effects of NXT007 Compared to Factor VIII Prophylaxis in Participants With Hemophilia A

    Trial Treatment · Phase 3 · Hoffmann-La Roche

    University of Colorado Hemophilia and Thrombosis Center, Aurora · University of Iowa Hospitals and Clinics, Iowa City

    Registry updated 2026-10-26

  • NCT07895381

    A Study to Describe Patient REal-world FitusiRan ExpeRience

    Research · Sanofi

    Concentrics Center for Research, Indianapolis

    Registry updated 2026-10-26

  • NCT05932914

    Liver Biopsy Following Gene Therapy For Hemophilia

    Research · St. Jude Children's Research Hospital

    St. Jude Children's Research Hospital, Memphis

    Registry updated 2026-10-22

  • NCT06379789

    A Study to Investigate the Safety and Effectiveness of a Coagulation Factor IX Gene Insertion Therapy (REGV131-LNP1265) in Pediatric, Adolescent and Adult Participants With Hemophilia B

    Trial Treatment · Phase 1/2 · Regeneron Pharmaceuticals

    University of Michigan, Ann Arbor · University of Colorado Hemophilia and Thrombosis Center, Aurora · Nationwide Children's Hospital, Columbus · Children's Medical Center Dallas, Dallas · University of Florida, Gainesville · University of Texas Health Science Center at Houston, Houston · Indiana Hemophilia and Thrombosis Center, Indianapolis · Children's Hospital Los Angeles, Los Angeles · David Geffen School of Medicine at UCLA, Los Angeles · Orthopaedic Hemophilia Treatment Center, Los Angeles · Vanderbilt University Medical Center, Nashville · Yale HTC, New Haven · Tulane University School of Medicine, Louisiana Center for Bleeding and Clotting Disorders, New Orleans · Children's Hospital of Philadelphia (CHOP), Philadelphia · Phoenix Children s Hospital, Phoenix · University of California - Davis, Sacramento · University California San Francisco, San Francisco

    Registry updated 2026-10-21

  • NCT07080905

    Phase 3, Open-label, Single-dose Study of CSL222 in Adolescent Male Subjects (≥ 12 to < 18 Years of Age) With Severe or Moderately Severe Hemophilia B

    Trial Treatment · Phase 3 · CSL Behring

    University of Michigan Medical Center, Ann Arbor · Arthur M Blank Hospital - Children's Healthcare of Atlanta, Atlanta · University of Florida, Gainesville · St. Jude Children's Research Hospital, Memphis · Center for Inherited Blood Disorders, Orange · Rady Children's Hospital - San Diego, San Diego

    Registry updated 2026-10-20

  • NCT06703606

    A Study to Learn About How Changing Therapy From Emicizumab to Marstacimab Affects People With the Severe Hemophilia A.

    Trial Treatment · Phase 1 · Pfizer

    Brody School of Medicine at East Carolina University, Greenville · ECU Health Medical Center, Greenville · Altman Clinical and Translational Research Institute-IDS, La Jolla · Altman Clinical and Translational Research Institute, La Jolla · Orthopaedic Institute for Children/Orthopaedic Hemophilia Treatment Center, Los Angeles · UCSD Center for Bleeding and Clotting Disorders, San Diego

    Registry updated 2026-10-15

  • NCT06941870

    Efanesoctocog Alfa Prophylaxis in Patients With Hemophilia A With Synovial Hypertrophy

    Trial Treatment · Phase 4 · Sanofi

    The Ohio State University Wexner Medical Center - CarePoint East- Site Number : 8400001, Columbus · Indiana Hemophilia and Thrombosis Center- Site Number : 8400006, Indianapolis · University of Iowa- Site Number : 8400004, Iowa City · Orthopedic Institute for Children- Site Number : 8400009, Los Angeles · Washington Center for Bleeding Disorders- Site Number : 8400008, Seattle

    Registry updated 2026-10-15

  • NCT05611801

    A Clinical Trial of Study Medicine (Marstacimab) in Pediatric Patients With Hemophilia A or Hemophilia B

    Trial Treatment · Phase 3 · Pfizer

    Intermountain - Primary Children's Hospital, Salt Lake City

    Registry updated 2026-10-14

  • NCT07226206

    A Gene Therapy Study of SPK-8011QQ in Adults With Severe or Moderately Severe Hemophilia A

    Trial Treatment · Phase 1/2 · Hoffmann-La Roche

    Newark Beth Israel Medical Center, Newark · Yale School of Medicine, New Haven · New York Presbyterian Hospital - Weill-Cornell, New York · Center for Inherited Blood Disorders, Orange · University of California San Francisco, San Francisco · Kaiser Permanente, Vallejo

    Registry updated 2026-10-13

  • NCT05568719

    Safety and Effectiveness of Giroctocogene Fitelparvovec or Fidanacogene Elaparvovec in Patients With Hemophilia A or B Respectively

    Trial Treatment · Phase 3 · Pfizer

    Innovative Hematology, Inc., Indianapolis · Mississippi Center for Advanced Medicine, Madison · Cornell University||Joan & Sanford I. Weill Medical College, New York · Weill Cornell Medical College-New York Presbyterian Hospital, New York · The Childrens Hospital of Philadelphia Division of Hematology, Philadelphia · The Regents of the University of California||UC Davis Health, Rancho Cordova · UC Davis Ambulatory Care Clinic, Sacramento · UC Davis Hemophilia Treatment Center, Sacramento · UC Davis Health, Sacramento · UC Davis Medical Center, Sacramento · UCSF Outpatient Hematology Clinic, San Francisco · Washington Institute for Coagulation, Seattle · The University of South Florida Board of Trustees, Tampa · USF Health Morsani Center for Advanced Healthcare, Tampa

    Registry updated 2026-10-07

  • NCT07582276

    Registry updated 2026-10-05

  • NCT07692217

    TG-INSIGHT With Joint POCUS, Hemostatic Potential in Patients With Severe Hemophilia A on Novel Replacement and Substitution FVIII Therapies

    Research · University of Texas Southwestern Medical Center

    The University of Texas Southwestern Medical Center, Dallas

    Registry updated 2026-09-29

  • NCT04023019

    Treatment of Hemophilia A Patients With FVIII Inhibitors

    Research · Phase 4 · Emory University

    Arthur M Blank Hospital, Atlanta

    Registry updated 2026-09-23

  • NCT06145373

    A Study to Test a Medicine (Fitusiran) for Preventing Bleeds in People With Severe Hemophilia Who Previously Received Preventive Treatment With Emicizumab

    Trial Treatment · Phase 4 · Sanofi

    Flowood · Children's Hospital Los Angeles- Site Number : 8400005, Los Angeles

    Registry updated 2026-09-23

  • NCT07220564

    A Research Study Looking at How Different Doses of Study Medicine (Inno8) Work in the Body of People With Haemophilia A

    Trial Treatment · Phase 1 · Novo Nordisk A/S

    UC Denver Hemoph & Thrombo Ctr, Aurora · Penn State MS Hershey Med Ctr, Hershey · Indiana Hemophilia-Thromb Ctr, Indianapolis · University Of Iowa_Iowa City, Iowa City · St Christopher Hosp for Child, Philadelphia

    Registry updated 2026-09-18

  • NCT06003387

    Efficacy and Safety of CSL222 (Etranacogene Dezaparvovec) Gene Therapy in Adults With Hemophilia B With Pretreatment Adeno-associated Virus Serotype 5 (AAV5) Neutralizing Antibodies (Nabs)

    Trial Treatment · Phase 3 · CSL Behring

    University of Michigan, Ann Arbor · The University of Texas Health Science Center at Houston, Houston · Hemophilia Center of Western Pennsylvania (HCWP), Pittsburgh · University of California, San Diego (UCSD), San Diego

    Registry updated 2026-08-27

  • NCT04278404

    Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

    Research · Duke University

    University of New Mexico Health Science Center, Albuquerque · Colorado University Denver, Aurora · The Children's Hospital Colorado, Aurora · Dell Children's Medical Center of Central Texas, Austin · University of Maryland Medical Center, Baltimore · Boston Children's Hospital, Boston · University of North Carolina at Chapel Hill, Chapel Hill · Medical University of South Carolina Children's Hospital, Charleston · Ann and Robert H Lurie Childrens Hospital of Chicago, Chicago · Cincinnati Childrens Hospital Medical Center, Cincinnati · University of South Carolina, Columbia · University of Texas Southwestern Medical Center - Dallas, Dallas · Duke University Health System, Durham · Pennsylvania State University--Hershey Children's Hospital, Hershey · Kapiolani Womens and Childrens Medical Center, Honolulu · The Womens Hospital of Texas, Houston · Baylor College of Medicine, Houston · University of Texas--Memorial Hermann Texas Medical Center, Houston · Riley Hospital for Children at Indiana University, Indianapolis · University of Iowa Stead Family Children's Hospital, Iowa City · University of Mississippi Medical Center, Jackson · University of Florida Jacksonville Shands Medical Center, Jacksonville · Children's Mercy Hospital, Kansas City · University of Kansas Medical Center-JG Kidney Institute, Kansas City · Dartmouth Hitchcock Medical Center, Lebanon · Massachusetts General Hospital, Lexington · Arkansas Children's Hospital Research Institute, Little Rock · University of California Los Angeles Medical Center, Los Angeles · University of Louisville Norton Childrens Hospital, Louisville · University Wisconsin Madison, Madison · Mississippi Center for Advanced Medicine, Madison · University of Wisconsin, Madison · Medical College of Wisconsin, Milwaukee · University of Minnesota, Minneapolis · West Virginia University Hospital, Morgantown · Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville · Tulane University Health Science Center, New Orleans · Ochsner Baptist Clinical Trials Unit, New Orleans · Board of Regents of the University of Oklahoma, Oklahoma City · University of Nebraska Medical Center, Omaha · Lucile Packard Children's Hospital, Palo Alto · Phoenix Children s Hospital, Phoenix · Oregon Health and Science University, Portland · Rhode Island Hospital, Providence · University of Utah, Salt Lake City · Seattle Children's Hospital, Seattle · Avera McKennan Hospital & University Medical Center, Sioux Falls · Alfred I duPont Hospital for Children, Wilmington

    Registry updated 2026-08-21

  • NCT04563520

    SAFE Study: Safety of aPCC Following Emicizumab Prophylaxis

    Trial Treatment · Phase 3 · Emory University

    Emory University Hospital, Atlanta · Children's Healthcare of Atlanta, Atlanta

    Registry updated 2026-08-21

  • NCT04398628

    ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders

    Research · American Thrombosis and Hemostasis Network

    Akron Children's Hospital - Showers Center for Cancer & Blood Disorders, Akron · University of New Mexico Ted R. Montoya Hemophilia & Thrombosis Program, Albuquerque · Comprehensive Bleeding Disorders Center at Emory University and Children's Healthcare of Atlanta, Atlanta · Emory/Children's Health Care of Atlanta, Atlanta · Children's Blood and Cancer Center of Central Texas, Austin · Johns Hopkins University Hemophilia Treatment Center, Baltimore · Massachusetts General Hospital Comprehensive Hemophilia and Thrombosis Treatment Center, Boston · Western New York BloodCare, Buffalo · Comprehensive Hemophilia Treatment Center, University of North Carolina at Chapel Hill, Chapel Hill · St. Jude Affiliate Clinic at Novant Health Hemby Children's Hospital, Charlotte · Rush University Medical Center, Chicago · Cincinnati Children's Hospital Medical Center, Hemophilia & Thrombosis Center, Cincinnati · University of Cincinnati Medical Center Hemophilia Treatment Center, Cincinnati · University Hospitals Health System Cleveland, Cleveland · Nationwide Children's Hospital, Columbus, Columbus · Ohio State University Medical Center, Columbus · North Texas Hemophilia and Thrombosis Program - Pediatric Program / Center for Cancer & Blood Disorders, Dallas · North Texas Comprehensive Hemophilia Treatment Center, Dallas · Dayton Children's Hemostasis and Thrombosis Center, Dayton · Central Michigan Children's Hospital of Michigan, Detroit · Henry Ford Health System Bleeding and Thrombosis Treatment Center, Detroit · University of Florida Hemophilia Treatment Center, Gainesville · Hemophilia Outreach Center Green Bay, Green Bay · East Carolina University Hemophilia Treatment Center, Greenville · Connecticut Children's Medical Center, Hartford · Texas Children's Hemophilia & Thrombosis Center/Baylor College of Medicine, Houston · Gulf States Hemophilia and Thrombophilia Center, Houston · Northwell Health Hemostasis and Thrombosis Center at Long Island Jewish and Cohen Children's Medical Center, Hyde Park · Indiana Hemophilia and Thrombosis Center, Indianapolis · Iowa Hemophilia and Thrombosis Center, Iowa City · Children's Mercy Hospital, Kansas City, Kansas City · Cure 4 the Kids Foundation, Las Vegas · Arkansas Center for Bleeding Disorders, Little Rock · Orthopaedic Institute for Children HTC, Los Angeles · Childrens Hospital Los Angeles, Los Angeles · St. Jude Children's Research Hospital, Memphis · University of Miami Comprehensive Hemophilia Treatment Center, Miami · University of Miami Hospital and Clinics, Miami · Comprehensive Center for Bleeding Disorders, Milwaukee · Vanderbilt University Medical Center, Nashville · Newark Beth Israel Medical Center - Hemophilia Center, Newark · Yale Hemophilia Treatment Center, New Haven · Louisiana Center for Bleeding and Clotting Disorders, Tulane University, New Orleans · Weill Cornell Medical College-New York Presbyterian Hospital, New York · Children's Hospital of Kings Daughters, Norfolk · UCSF Benioff Children's Hospital Oakland, Oakland · Arnold Palmer Hospital for Children - The Haley Center for Children's Cancer and Blood Disorders, Orlando · Bleeding and Clotting Disorders Institute, Peoria · Penn Comprehensive Hemophilia and Thrombophilia Program/Hospital of the University of Pennsylvania, Philadelphia · St. Christopher's Hospital for Children, Philadelphia · Children's Hospital of Philadelphia, Philadelphia · Arizona Hemophilia and Thrombosis Treatment Center at Phoenix Children's Hospital, Phoenix · Hemophilia Center of Western Pennsylvania, Pittsburgh · Rhode Island Hospital Hemostasis and Thrombosis Center, Providence · Hemostasis and Thrombosis Center of Nevada, Reno · American Thrombosis and Hemostasis Network, Rochester · Mayo Comprehensive Hemophilia Center, Rochester · University of California at Davis Hemophilia Treatment Center, Sacramento · South Texas Comprehensive Hemophilia and Thrombophilia Treatment Center, San Antonio · Loma Linda Hemoglobinopathy and Inherited Bleeding Disorder Program, San Bernardino · Rady Children's Hospital - San Diego, San Diego · Hemophilia & Thrombosis Treatment Center at UC San Diego Health, San Diego · University of California, San Francisco Hemophilia & Thrombosis Center, San Francisco · Memorial Health University Medical Center, Savannah · Maine Hemophilia and Thrombosis Center, Scarborough · Washington Center for Bleeding Disorders, Seattle · The John Bouhasin Center for Children with Bleeding Disorders, St Louis · Johns Hopkins All Children's Hospital, St. Petersburg · University of South Florida - Adult, Tampa · St. Joseph's Hospital Center for Bleeding & Clotting Disorders, Tampa · Montefiore Medical Center, The Bronx · Northwest Ohio Hemophilia Treatment Center at the Toledo Hospital, Toledo · Georgetown University, Washington D.C. · Children's National Hemophilia Center, Washington D.C. · Delaware Hemophilia Treatment Center, Wilmington · Wake Forest University Health Sciences, Winston-Salem

    Registry updated 2026-08-17

All Haemophilia trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

Haemophilia trials in United States – Frontlight Research