HIV: open trials in United States

364 open trials have a site in United States. Registry data; only the trial team decides who can take part.

NCT00767312
Analysis of HIV-1 Replication During Antiretroviral Therapy
Research · National Institute of Allergy and Infectious Diseases (NIAID)
National Institutes of Health Clinical Center, Bethesda
Registry updated 2026-10-29
NCT01730131
Natural History Study of Progressive Multifocal Leukoencephalopathy (PML)
Research · National Institute of Neurological Disorders and Stroke (NINDS)
National Institutes of Health Clinical Center, Bethesda
Registry updated 2026-10-29
NCT05935644
ORCHID: An Online Intervention for Persons With HIV (Miami)
Trial Treatment · University of Miami
University of Miami School of Medicine, Miami
Registry updated 2026-10-29
NCT06949800
CASCADE 2002: PROTECT Study, "PRObiotics to TrEat Anal preCancer Trial
Trial Treatment · Phase 2 · University of California, San Francisco
University of California San Francisco, San Francisco
Registry updated 2026-10-29
NCT06987318
A Study to Evaluate the Safety and Antiviral Activity of Two Human Monoclonal Antibodies (VRC07-523LS and PGT121.414.LS) During Analytic Treatment Interruption in Participants Living With HIV Who Initiated ART During Acute/Early HIV-1 Infection
Trial Treatment · Phase 1 · National Institute of Allergy and Infectious Diseases (NIAID)
The Ponce de Leon Center CRS, Atlanta · University of Colorado Hospital CRS (Site #6101), Aurora · Alabama CRS (Site # 31788), Birmingham · Massachusetts General Hospital CRS (MGH CRS), Boston · Chapel Hill CRS, Chapel Hill · Northwestern University CRS (Site # 2701), Chicago · Ohio State University CRS, Columbus · Houston Advancing Research Team CRS (Site # 31473), Houston · Penn Therapeutics CRS (Site #6201), Philadelphia · UCSD Antiviral Research Center CRS, San Diego
Registry updated 2026-10-29
NCT07031219
HIV/HBV/HCV Triple Screening in Primary Care
Trial Treatment · University of Texas Southwestern Medical Center
University of Texas Southwestern Medical Center, Dallas
Registry updated 2026-10-29
NCT07462767
Precision Microbiota Interventions for Senoreduction Trial
Trial Treatment · Phase 1/2 · Louisiana State University Health Sciences Center in New Orleans
LSU Health, New Orleans
Registry updated 2026-10-29
NCT04139304
A Study of Daratumumab and Dose-Adjusted EPOCH in Plasmablastic Lymphoma
Trial Treatment · Early phase 1 · AIDS Malignancy Consortium
Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore · University of North Carolina, Chapel Hill, Chapel Hill · University of Illinois at Chicago, Chicago · The Ohio State University, Columbus · The University of Texas MD Anderson Cancer Center, Houston · University of Miami Miller School of Medicine, Miami · Memorial Sloan-Kettering Cancer Center, New York · University of Pennsylvania, Philadelphia · Huntsman Cancer Institute/University of Utah, Salt Lake City
Registry updated 2026-10-28
NCT07901101
Starting HIV Prevention Medicine (PrEP) During an Emergency Department Visit With a Peer Navigator
Trial Treatment · Phase 4 · University of South Florida
Tampa General Hospital, Tampa
Registry updated 2026-10-28
NCT00029445
Leukapheresis to Obtain Plasma or Lymphocytes for Studies of HIV-infected Patients, Including Long-term Non-progressors
Research · National Institute of Allergy and Infectious Diseases (NIAID)
National Institutes of Health Clinical Center, Bethesda
Registry updated 2026-10-27
NCT04375800
Doravirine (DOR) in Human Immunodeficiency Virus (HIV)-Infected Children Aged 4 Weeks to <12 Years and <45 kg (MK-1439-066)
Trial Treatment · Phase 2 · Merck Sharp & Dohme LLC
Emory Children's Center (Site 0103), Atlanta · University of Colorado at Denver (Site 0108), Aurora
Registry updated 2026-10-27
NCT07342491
Dasatinib for HIV-1 Reservoir Reduction
Trial Treatment · Phase 1 · National Institute of Allergy and Infectious Diseases (NIAID)
Northwestern University CRS (Site # 2701), Chicago · Cleveland · 1401, University of Washington Positive Research CRS, Seattle
Registry updated 2026-10-27
NCT07647432
HEME-25 Open-Label Feasibility Study of Elranatamab Utilized as Consolidation in Newly Diagnosed Plasmablastic Lymphoma With or Without HIV
Trial Treatment · Phase 1 · University of Illinois Chicago
University of Illinois at Chicago, Chicago
Registry updated 2026-10-26
NCT07792161
Supporting Health and Empowerment Through Contingency Management and Affect Regulation
Trial Treatment · Wake Forest University Health Sciences
Atrium Health Wake Forest Baptist, Winston-Salem
Registry updated 2026-10-26
NCT07895823
Reaching Persons With HIV Who Are Out of Care Through Expedited Access to Long-Acting Injectable Antiretroviral Therapy - The RELAI Study
Trial Treatment · Phase 4 · University of North Carolina, Chapel Hill
University of North Carolina at Chapel Hill, Chapel Hill
Registry updated 2026-10-26
NCT06003192
Screen Smart: Using Digital Health to Improve HIV Screening and Prevention
Trial Treatment · Children's Hospital Medical Center, Cincinnati
Nationwide Children's Hospital, Columbus · Children's Wisconsin, Milwaukee · Children's Hospital of Philadelphia, Philadelphia · University of Utah, Salt Lake City
Registry updated 2026-10-23
NCT07757802
Phase 1 Study of CH505 HIV Vaccine Nanoparticles and mRNA Boosters in Healthy Adults
Trial Treatment · Phase 1 · National Institute of Allergy and Infectious Diseases (NIAID)
The Ponce de Leon Center CRS Site# 5802, Atlanta · Boston · Brigham and Women's Hospital Vaccine CRS (BWH VCRS) Site# 30007, Boston · Vanderbilt Vaccine (VV) CRS Site# 30352, Nashville · Philadelphia · University of Pittsburgh CRS Site# 1001, Pittsburgh · University of Rochester Vaccines to Prevent HIV Infection CRS Site# 31467, Rochester · San Francisco
Registry updated 2026-10-23
NCT07871552
Effects of Switch to Doravirine/Islatravir vs. Continued Antiretroviral Therapy on Biomarkers of Aging Among Virologically Suppressed People With HIV
Trial Treatment · Phase 2 · The University of Texas Health Science Center, Houston
University of Colorado Anschutz Medical Center, Aurora · The University of Texas Health Science Center at Houston, Houston
Registry updated 2026-10-23
NCT07892664
Reducing Arterial Inflammation Using Eplerenone and Statins in HIV
Trial Treatment · Phase 2/3 · Massachusetts General Hospital
Massachusetts General Hospital, Boston · UCLA Center for Clinical AIDS Research and Education (CARE), Los Angeles
Registry updated 2026-10-23
NCT07473778
Implementation Study of Lenacapavir Pre-exposure Prophylaxis for HIV Prevention
Research · Gilead Sciences
Grady Memorial Hospital, Atlanta · Faebris Medical & Community Education, Atlanta · Chase Brexton Health Care, Baltimore · Be Well Medical Center, Berkley · Pacific Oaks Medical Group, Beverly Hills · UAB, 1917 Research Clinic, Birmingham · Fenway Health, Boston · Medical University of South Carolina, Charleston · West Virginia Health Right, Inc., Charleston · Howard Brown Health, Chicago · Rush University Medical Center/Division of Infectious Diseases, Chicago · Northwestern Medicine, Chicago · Ruth M. Rothstein CORE Center, Chicago · DOM/Project WISH Research Clinic, Chicago · University of Cincinnati College of Medicine, Cincinnati · Ohio State University Infectious Diseases Clinical Trials Unit, Columbus · Prism Health, Dallas · Abounding Prosperity Inc., Dallas · Vivent Health, Denver · Henry Ford Health, Detroit · UT Health, Houston · Thomas Street at Quentin Mease Health Center, Houston · KC CARE Health Center, Kansas City · Ruane Clinical Research Group Inc., Los Angeles · CAN Community Health, Miami · The Aliveness Project, Minneapolis · Vanderbilt University Medical Center, Nashville · Ochsner Baptist Medical Center, New Orleans · The Clinic NOLA, New Orleans · Colombia University Irving Medical Center, New York · NYC Health + Hospitals / Bellevue, New York · Sutter Health- East Bay Advanced Care, Oakland · University of Nebraska Medical Center/Nebraska Medicine Specialty Care Center, Omaha · Bliss Health, Orlando · Pineapple Healthcare Orlando, Orlando · AHF Pensacola, Pensacola · Perelman Center for Advanced Medicine, Philadelphia · Philadelphia FIGHT, Philadelphia · Family Health Centers of San Diego, San Diego · UC San Diego (UCSD) AntiViral Research Center (AVRC), San Diego · Kelley-Ross Pharmacy, Seattle · Washington University School of Medicine Infectious Disease Clinical Research Unit, St Louis · BronxCare Health System, The Bronx · Mills Clinical Research, West Hollywood
Registry updated 2026-10-21
NCT06648629
Acceptance and Commitment Therapy for HIV+ Hazardous Drinkers
Trial Treatment · Syracuse University
Syracuse University, Syracuse
Registry updated 2026-10-20
NCT07223398
Shared Decision Making to Treat Or Prevent (STOP) HIV in Criminal Legal Involved Populations (R33)
Trial Treatment · Yale University
University of Texas Southwestern Medical Center (UTSW), Dallas · Texas Christian University's (TCU) School of Medicine, Fort Worth · College of Medicine at the University of Kentucky, Lexington · Yale School of Medicine, New Haven
Registry updated 2026-10-20
NCT07520188
C-3002: Enhancing Cervical Cancer Screening Access and Follow-up Care at 'CASCADE' Clinical Sites in the United States
Research · UNC Lineberger Comprehensive Cancer Center
Emory University SOM Division/Department: Gynecology & Obstetrics, Atlanta · University of Maryland School of Medicine Division of Family and Community Medicine, Baltimore
Registry updated 2026-10-20
NCT07599722
mHealth Service Linkage for Young Adults Impacted by the Criminal Legal System
Trial Treatment · University of Pittsburgh
University of Pittsburgh, School of Public Health, Pittsburgh
Registry updated 2026-10-20
NCT06462807
Enhancing the Organizational Social Context to Improve Viral Suppression and Retention in HIV Care
Trial Treatment · University of Pennsylvania
University of Pennsylvania, Philadelphia
Registry updated 2026-10-19

All HIV trials and the map

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