High blood pressure: open trials in South Africa

8 open trials have a site in South Africa. Registry data; only the trial team decides who can take part.

NCT07919405
A Research Study to Investigate How Well the Medicine CagriSema Lowers High Blood Pressure in People Living With High Blood Pressure and Obesity
Trial Treatment · Phase 3 · Novo Nordisk A/S
Dr Vawda's site, Durban · Dr T Padayachee, eMkhomazi · Dr Moosa's Rooms, Gauteng · Soweto Clinical Trial Centre, Johannesburg · Johannesburg · Dr A Jacovides and Partners Inc, Midrand
Registry updated 2026-11-05
NCT05179876
A Study Providing Treatment Access in Participants With Pulmonary Hypertension Completing a Parent Study and Having no Other Option
Trial Treatment · Phase 3 · Actelion
Abdullah, IA, Durban · Dr Kalla, Lenasia
Registry updated 2026-11-03
NCT05587712
Study to Evaluate Sotatercept (MK-7962) in Children With Pulmonary Arterial Hypertension (PAH) (MK-7962-008)
Trial Treatment · Phase 2 · Merck Sharp & Dohme LLC
Wits Clinical Research-Chris Hani Baragwanath Hospital ( Site 1201), Johannesburg, Soweto
Registry updated 2026-11-02
NCT07064473
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
Trial Treatment · Phase 3 · Boehringer Ingelheim
Lakeview Hospital, Benoni · IATROS International, Bloemfontein · Tread Research, Cape Town · Langeberg Clinical Trials, Cape Town · Paarl Research Centre, Cape Town · Johese Clinical Research: Midstream, Centurion · Canal Walk Clinical Trial Centre, Century City · Synapta Clinical Research Centre, Durban · Prof N Ranjith Cardiovascular Research Centre, Durban · Clinresco Centre, Gauteng · Lenasia Clinical Trial Centre, Johannesburg · Life The Glynnwood, Johannesburg · Diabetes Care Centre, Johannesburg · Dr Garda Cardiology Practice, Johannesburg · Drs H & V Makan, Johannesburg · Meditrial, Pietermaritzburg · Clinical Trial Systems (Pty) Ltd, Pretoria · Jongaie Research, Pretoria · Dr I.O Ebrahim Inc, Pretoria · Diabetes Care Centre, Pretoria · Global Clinical Trials, Raslouw · Helderberg Research Institute, Somerset West · Vergelegen Medi-Clinic, Somerset West · Wits Clinical Research Chris Hani Baragwanath Hospital, Soweto · Tiervlei Trial Centre, Tygervalley · Clinical Projects Research, Worcester · CareKahle Pty Ltd, Wynberg
Registry updated 2026-10-28
NCT07181109
Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease
Trial Treatment · Phase 3 · Alnylam Pharmaceuticals
Belville · Bloemfontein · Cape Town · Chatsworth · City of Johannesburg · Durban · Ekurhuleni · Gauteng · Johannesburg · KwaDukuza · KwaZulu - Natal · Mogale City · Mossel Bay · Nelson Mandela Bay · Plettenberg Bay · Pretoria · Soweto · Worcester
Registry updated 2026-10-15
NCT06742723
A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure
Trial Treatment · Phase 3 · AstraZeneca
Bellville · Benoni · Bloemfontein · Cape Town · Durban · Johannesburg · KwaDukuza · Lenasia · Midrand · Newton · Parow
Registry updated 2026-09-25
NCT03549754
iCaReMe Global Registry: Multinational Real-world Evidence in Cardiorenal and Metabolic Diseases
Research · AstraZeneca
Florida · Parow · Umhlanga
Registry updated 2026-09-09
NCT05982847
National Blood Pressure Screening in Children to Improve Paediatric Healthcare in South Africa
Research · North-West University, South Africa
University of the Free State, Bloemfontein · Red Cross War Memorial Children Hospital, Cape Town · South African Medical Research Council, Cape Town · University of Cape Town, Cape Town · University of KwaZulu-Natal, Durban · University of the Witwatersrand, Johannesburg · Walter Sisulu University, Mthatha · University of Limpopo, Polokwane · Nelson Mandela Metropolitan University, Port Elizabeth · Hypertension in Africa Research Team (HART), North-West University, Potchefstroom
Registry updated 2026-04-07

All High blood pressure trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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