Liver and biliary tract cancer trials in Australia

In Australia 45 Also abroad 1314

45 trials · From ClinicalTrials.gov, checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 1/2Taking people
A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors
Where
Frankston, Sydney
Age
18 years and over
People
616 worldwide
Run by
Verastem, Inc.
See details and how to joinNCT07020221
Phase 3Taking people
Study Comparing BGB-B2033 With Sorafenib or Lenvatinib in Advanced Hepatocellular Carcinoma
Where
South Brisbane
Age
18 years and over
People
492 worldwide
Run by
BeOne Medicines
See details and how to joinNCT07836530 · EU 2026-526462-25-00
Phase 2Taking people
A Study to Learn More About How Well Treatment With Sevabertinib (BAY 2927088) Tablets Works and How Safe it is in Participants Who Have a Solid Tumor With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)
Where
Blacktown, Southport, Sydney
Age
18 years and over
People
111 worldwide
Run by
Bayer
See details and how to joinNCT06760819 · EU 2024-517419-62-00
Phase 1/2Taking people
A Clinical Study of MK-2870 Alone or With Other Treatments to Treat Gastrointestinal Cancers (MK-9999-02A)
Where
Brisbane, East Melbourne, Frankston, Nedlands, Westmead
Age
18 years and over
People
220 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT06428409 · EU 2023-508703-21-00
Phase 2Taking people
DB-1311 in Combination With BNT327 or DB-1305 in Advanced/Metastatic Solid Tumors
Where
Adelaide, Benowa, Birtinya, North Sydney
Age
18 years and over
People
750 worldwide
Run by
DualityBio Inc.
See details and how to joinNCT06953089 · EU 2025-523895-22-00
Phase 1/2Taking people
SumMET: Study of [225Ac]Ac-FL-261 in Participants With Solid Tumors Overexpressing c-MET
Where
Nedlands
Age
18 years and over
People
208 worldwide
Run by
Full-Life Technologies UK Limited
See details and how to joinNCT07873450
Phase 1Taking people
A Study of MGC026 in Participants With Advanced Solid Tumors
Where
Auchenflower, Heidelberg, Kurralta Park
Age
18 years and over
People
394 worldwide
Run by
MacroGenics
See details and how to joinNCT06242470
No phaseTaking people
Observational Study Protocol: LIVER-R
Where
Garran, Heidelberg, Melbourne, Murdoch
Age
18 years to 130 years
People
4,000 worldwide
Run by
AstraZeneca
See details and how to joinNCT06252753
Phase 1/2Taking people
A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02)
Where
Blacktown, Mount Kuring-Gai, St Leonards, Subiaco, Woolloongabba
Age
18 years and over
People
680 worldwide
Run by
Daiichi Sankyo
See details and how to joinNCT06330064 · EU 2023-509632-26-00
Phase 1/2Taking people
A Study to Evaluate the Safety and Tolerability of Pumitamig Alone or In Combination With Ipilimumab in Participants With First-Line Advanced or Unresectable Hepatocellular Carcinoma (HCC) (ROSETTA HCC-206)
Where
Birtinya, Camperdown, Parkville, Westmead
Age
18 years and over
People
198 worldwide
Run by
Bristol-Myers Squibb
See details and how to joinNCT07291076 · EU 2025-523602-33-00
Phase 1/2Taking people
A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors
Where
Birtinya, Blacktown, Brisbane, Camperdown, Concord, Gold Coast, Nedlands, New Lambton Heights, Sydney, Waratah
Age
18 years and over
People
862 worldwide
Run by
DualityBio Inc.
See details and how to joinNCT05914116
Phase 1/2Taking people
A Clinical Trial to Test if the Investigational Drug BNT329 is Safe and Potentially Beneficial for People With Advanced Solid Tumors Known to Express the Tumor Marker CA19-9
Where
Clayton, Heidelberg
Age
18 years and over
People
245 worldwide
Run by
BioNTech SE
See details and how to joinNCT07186842 · EU 2025-522613-26-00
Phase 1Taking people
Study to Assess Adverse Events and Change in Disease Activity in Adult Participants With Select Advanced Solid Tumor Indications Receiving Intravenous (IV) ABBV-400
Where
Camperdown, Heidelberg
Age
18 years and over
People
325 worldwide
Run by
AbbVie
See details and how to joinNCT06084481 · EU 2023-506227-29-00
Phase 3Taking people
Phase 3 Study of T-DXd and Rilvegostomig Versus SoC in Advanced HER2-expressing Biliary Tract Cancer
Where
Chermside, Clayton, Concord, Nedlands
Age
18 years to 99 years
People
620 worldwide
Run by
AstraZeneca
See details and how to joinNCT06467357 · EU 2023-508057-19-00
Phase 3Taking people
Phase III Study of Rilvegostomig in Combination With Bevacizumab With or Without Tremelimumab as First-line Treatment of Hepatocellular Carcinoma
Where
Camperdown, Clayton, Heidelberg, Randwick, South Brisbane
Age
18 years and over
People
1,220 worldwide
Run by
AstraZeneca
See details and how to joinNCT06921785 · EU 2024-518210-81-00
Phase 1/2Taking people
FOG-001 in Locally Advanced or Metastatic Solid Tumors
Where
Melbourne, South Brisbane
Age
18 years and over
People
619 worldwide
Run by
Parabilis Medicines, Inc.
See details and how to joinNCT05919264
Phase 1/2Taking people
The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
Where
Bedford Park, Camperdown, Clayton, Nedlands, South Brisbane
Age
12 years and over
People
300 worldwide
Run by
PMV Pharmaceuticals, Inc
See details and how to joinNCT04585750
Phase 1Taking people
Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors
Where
Albury, Birtinya, Brisbane, Saint Leonards, Sydney
Age
18 years and over
People
1,394 worldwide
Run by
Exelixis
See details and how to joinNCT05176483 · EU 2023-510061-10-00
Phase 2Taking people
AZD0901 in Participants With Advanced Solid Tumours Expressing Claudin18.2
Where
Melbourne, Murdoch, Randwick
Age
18 years and over
People
226 worldwide
Run by
AstraZeneca
See details and how to joinNCT06219941 · EU 2023-508275-37-00
Phase 3Taking people
A Study of Rilvegostomig or Durvalumab Plus Chemotherapy for First-Line Treatment of Biliary Tract Cancer (ARTEMIDE-Biliary02)
Where
Clayton, Darlinghurst, Gosford, Murdoch, South Brisbane
Age
18 years and over
People
1,100 worldwide
Run by
AstraZeneca
See details and how to joinNCT07221253 · EU 2025-523085-24-00
Phase 1/2Taking people
Clinical Trial of YH32367 in Patients With HER2 Positive Locally Advanced or Metastatic Solid Tumor
Where
Adelaide, Melbourne, Perth, Sydney
Age
18 years and over
People
147 worldwide
Run by
Yuhan Corporation
See details and how to joinNCT05523947
Phase 1Taking people
A Phase I Dose Escalation and Dose Expansion Study to Investigate the Pharmacokinetics and Safety of Subcutaneous Durvalumab
Where
Fitzroy, St Albans, Woolloongabba
Age
18 years and over
People
40 worldwide
Run by
AstraZeneca
See details and how to joinNCT07391670 · EU 2025-521639-34-00
Phase 1/2Taking people
SL-28 for Advanced Solid Tumours
Where
Adelaide, Gold Coast, Sydney
Age
18 years and over
People
60
Run by
Second Life Therapeutics
See details and how to joinNCT07341737
Phase 2Taking people
Study of Futibatinib in Patients With Advanced Cholangiocarcinoma With FGFR2 Fusion or Rearrangement
Where
Melbourne, Subiaco, Sydney
Age
18 years and over
People
120 worldwide
Run by
Taiho Oncology, Inc.
See details and how to joinNCT05727176 · EU 2023-503665-39-00
Phase 1/2Taking people
A Phase 1/2a Study of DB-1303/BNT323 in Advanced/Metastatic Solid Tumors
Where
Melbourne, Randwick, South Brisbane, Sydney
Age
18 years and over
People
796 worldwide
Run by
DualityBio Inc.
See details and how to joinNCT05150691