Lung cancer trials in Australia

In Australia 164 Also abroad 2733

164 trials · From ClinicalTrials.gov, checked 12 November 2026. Ask the study team whether a trial fits you.

Phase 1Taking people
Beamion LUNG-1: A Study to Test Different Doses of Zongertinib in People With Different Types of Advanced Cancer (Solid Tumours With Changes in the HER2 Gene)
Where
Macquarie Park
Age
18 years and over
People
554 worldwide
Run by
Boehringer Ingelheim
See details and how to joinNCT04886804 · EU 2024-511246-39-00
Phase 1Taking people
A Study of MGC026 in Participants With Advanced Solid Tumors
Where
Auchenflower, Heidelberg, Kurralta Park
Age
18 years and over
People
394 worldwide
Run by
MacroGenics
See details and how to joinNCT06242470
Phase 3Taking people
Phase III, Open-label, Study of First-line Dato-DXd in Combination With Rilvegostomig for Advanced Non-squamous NSCLC With High PD-L1 Expression (TC ≥ 50%) and Without Actionable Genomic Alterations
Where
Birtinya, Blacktown, Clayton, Gosford, Melbourne, South Brisbane, Wodonga
Age
18 years and over
People
675 worldwide
Run by
AstraZeneca
See details and how to joinNCT06357533 · EU 2023-505077-32-00
Phase 3Taking people
A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Non-Squamous NSCLC
Where
Darlinghurst, Hyde Park, Southport, Wollongong
Age
18 years and over
People
1,160 worldwide
Run by
AstraZeneca
See details and how to joinNCT06627647 · EU 2024-515008-38-00
Phase 1/2Taking people
A Study of PRMT5 Inhibitor BAY 3713372 in Participants With MTAP-deleted Solid Tumors
Where
Camperdown, Concord, Epping, Waratah
Age
18 years and over
People
450 worldwide
Run by
Bayer
See details and how to joinNCT06914128 · EU 2025-520623-24-00
Phase 2Taking people
Study to Evaluate Sutetinib Maleate Capsule in Locally Advanced or Metastatic Non-small Cell Lung Cancer
Where
Birtinya, Subiaco, Sydney
Age
18 years and over
People
128 worldwide
Run by
Teligene US
See details and how to joinNCT05168566
Phase 1/2Taking people
Study to Evaluate Adverse Events and Efficacy of Intravenous (IV) Telisotuzumab Adizutecan in Combination With a PD-1 Immune Checkpoint Inhibitor in Adult Participants With Advanced or Metastatic Non-Squamous NSCLC With No Prior Treatment for Advanced Disease, and No Actionable Genomic Alterations
Where
Blacktown, Elizabeth Vale, Frankston, Townsville
Age
18 years and over
People
252 worldwide
Run by
AbbVie
See details and how to joinNCT06772623 · EU 2024-514465-18-00
Phase 3Taking people
A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4)
Where
Brisbane, Canberra, Elizabeth Vale, Frankston, Joondalup, Melbourne, North Tamworth, Orange, Traralgon
Age
18 years and over
People
630 worldwide
Run by
Mirati Therapeutics Inc.
See details and how to joinNCT06875310 · EU 2024-515698-85-00
Phase 1/2Not yet taking people in Australia
DAREON®-36: A Study to Test Obrixtamig in Combination With ZL-1310 in People With Advanced Small Cell Lung Cancer or Other Neuroendocrine Cancers
Where
Camperdown, St Leonards
Age
18 years and over
People
60 worldwide
Run by
Boehringer Ingelheim
See details and how to joinNCT07707895 · EU 2026-525634-27-00
Phase 1/2Taking people
Phase 1/2 Study of Intravenous Injection of STX-003 in Advanced Solid Tumors as Monotherapy or in Combination With Pembrolizumab
Where
Wollstonecraft
Age
18 years and over
People
220 worldwide
Run by
Strand Therapeutics Inc.
See details and how to joinNCT07751042
Phase 2Taking people
A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
Where
Camperdown, Chermside, Clayton, Hobart, Hyde Park
Age
18 years and over
People
740 worldwide
Run by
Daiichi Sankyo
See details and how to joinNCT06172478 · EU 2023-507641-29-00
Phase 2/3Taking people
Global, Multicenter Study of AMT-116 Versus Investigator's Choice in Participants With Advanced or Metastatic Non-squamous EGFR-Wildtype Non-Small Cell Lung Cancer (NSCLC) With Progression on or After Platinum-Based Chemotherapy and Anti-PD-1/PD-L1 Immunotherapy
Where
Coffs Harbour, Melbourne, Newcastle, Sydney
Age
18 years to 80 years
People
512 worldwide
Run by
Multitude Therapeutics Inc.
See details and how to joinNCT07718737
Phase 1Taking people
A Multinational Study Assessing an Oral EGFR Inhibitor, DZD6008 in Patients Who Have Advanced NSCLC With EGFR Mutations (TIAN-SHAN1)
Where
Blacktown, Camperdown
Age
18 years and over
People
140 worldwide
Run by
Dizal Pharmaceuticals
See details and how to joinNCT06905197
Phase 2/3Taking people
A Study to Compare the Combination of Navlimetostat (BMS-986504) With Pembrolizumab and Chemotherapy Versus Placebo Plus Pembrolizumab and Chemotherapy in First-line Metastatic Non-small Cell Lung Cancer Participants With Homozygous MTAP Deletion
Where
Ballarat Central, Birtinya, Brisbane, Elizabeth Vale, Garran, Hobart, Liverpool, St Leonards
Age
18 years and over
People
590 worldwide
Run by
Bristol-Myers Squibb
See details and how to joinNCT07063745 · EU 2025-521511-40-00
Phase 3Taking people
Primary Radiotherapy In MEtastatic Lung Cancer
Where
Adelaide, Ballarat, Blacktown, Gold Coast, Melbourne, Nedlands
Age
18 years and over
People
420
Run by
Trans Tasman Radiation Oncology Group
See details and how to joinNCT07135882
Phase 3Taking people
A Study to Evaluate the Efficacy of Pumitamig Versus Pembrolizumab in Participants With Previously Untreated Advanced Non-Small Cell Lung Cancer and PD-L1 ≥ 50%. (ROSETTA Lung-202)
Where
Ballarat Central, Elizabeth Vale, Epping, Gosford, Joondalup, Penrith
Age
18 years and over
People
750 worldwide
Run by
Bristol-Myers Squibb
See details and how to joinNCT07361510 · EU 2025-523586-18-00
Phase 2Taking people
A Study To Assess the Safety, Tolerability, and Efficacy of Imzokitug in Combination With Pumitamig and Platinum-Doublet Chemotherapy (PDCT) Versus Pumitamig and PDCT as First-line Treatment for Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
Where
Gosford, Greenslopes, Heidelberg, Perth, Westmead
Age
18 years and over
People
160 worldwide
Run by
Bristol-Myers Squibb
See details and how to joinNCT07680764 · EU 2026-525170-19-00
Phase 1/2Taking people
A Clinical Trial to Test if an Investigational Combination Therapy With BNT326 and BNT327 is Safe and Potentially Beneficial for People With Advanced Non-small Cell Lung Cancer (NSCLC)
Where
Adelaide, Kogarah, Saint Leonards, South Brisbane, Tugun, Westmead
Age
18 years and over
People
880 worldwide
Run by
BioNTech SE
See details and how to joinNCT07111520 · EU 2024-519344-32-00
Phase 2Taking people
Study of PF-07248144 in Advanced or Metastatic Solid Tumors
Where
Adelaide, Camperdown, Melbourne, Parkville, St Albans, Subiaco
Age
18 years and over
People
320 worldwide
Run by
Pfizer
See details and how to joinNCT04606446
Phase 1/2Taking people
A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors
Where
Birtinya, Blacktown, Brisbane, Camperdown, Concord, Gold Coast, Nedlands, New Lambton Heights, Sydney, Waratah
Age
18 years and over
People
862 worldwide
Run by
DualityBio Inc.
See details and how to joinNCT05914116
Phase 1/2Taking people
Intratumoral N17350 in Advanced Solid Tumors
Where
Melbourne, Newcastle, Westmead
Age
18 years and over
People
275 worldwide
Run by
Onchilles Pharma Inc
See details and how to joinNCT07339176
Phase 3Taking people
Study of Sacituzumab Govitecan Versus Standard of Care in Participants With Previously Treated Extensive Stage Small Cell Lung Cancer
Where
Adelaide, Fitzroy, Nedlands, New South Wales, Queensland, Southport
Age
18 years and over
People
695 worldwide
Run by
Gilead Sciences
See details and how to joinNCT06801834
Phase 1/2Taking people
Study of RAS(ON) Inhibitors in Patients With Advanced RAS-mutated NSCLC
Where
Camperdown, Clayton, Liverpool, Nedlands, St Leonards
Age
18 years and over
People
616 worldwide
Run by
Revolution Medicines, Inc.
See details and how to joinNCT06162221 · EU 2025-521147-21-00
Phase 1/2Taking people
A Study Evaluating FMC-376 in Participants With KRAS G12C Mutated Solid Tumors
Where
Box Hill, Kurralta Park, Macquarie Park, Nedlands, North Adelaide, Southport
Age
18 years and over
People
293 worldwide
Run by
Frontier Medicines Corporation
See details and how to joinNCT06244771
Phase 1/2Taking people
A Study to Evaluate DJI136, a DLL3-targeted CAR-T Therapy
Where
Clayton
Age
18 years and over
People
80 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT07564401