Lung cancer trials in Australia

In Australia 164 Also abroad 2733

164 trials · From ClinicalTrials.gov, checked 12 November 2026. Ask the study team whether a trial fits you.

Phase 1Taking people
Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors
Where
Albury, Birtinya, Brisbane, Saint Leonards, Sydney
Age
18 years and over
People
1,394 worldwide
Run by
Exelixis
See details and how to joinNCT05176483 · EU 2023-510061-10-00
Phase 1Taking people
Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors
Where
Melbourne, Randwick
Age
18 years and over
People
392 worldwide
Run by
TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics)
See details and how to joinNCT06625775 · EU 2024-519445-29-00
Phase 2Taking people
A Study of Intismeran Autogene (V940)/Placebo + Pembrolizumab and Chemotherapy in Metastatic Squamous Non-Small Cell Lung Cancer (V940-013)
Where
Nedlands, Westmead, Woolloongabba
Age
18 years and over
People
180 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT07221474 · EU 2025-520902-37-00
Phase 1Taking people
TLN-499 in Combination With Venetoclax in Patients With Relapsed/Refractory Solid Tumors
Where
Camperdown, Malvern, Nedlands
Age
18 years and over
People
120
Run by
Treeline Biosciences, Inc.
See details and how to joinNCT07713732
Phase 3Taking people
Neladalkib (NVL-655) for TKI-naive Patients With Advanced ALK-Positive NSCLC
Where
Heidelberg, Melbourne, Westmead
Age
18 years and over
People
450 worldwide
Run by
Nuvalent Inc.
See details and how to joinNCT06765109 · EU 2024-517553-26-00
Phase 3Taking people
This is a Study to Learn About How the Combination of the Study Medicines Sigvotatug Vedotin Plus Pembrolizumab Works in People With Non-small Cell Lung Cancer With High Levels of PD-L1.
Where
Birtinya, Coffs Harbour, Douglas, Gympie, Nambour, North Ryde, Perth, Sydney, Woolloongabba
Age
18 years and over
People
714 worldwide
Run by
Pfizer
See details and how to joinNCT06758401 · EU 2024-517968-36-00
Phase 3Taking people
A Global Phase III Study of Rilvegostomig or Pembrolizumab Monotherapy for First-Line Treatment of PD-L1-high Metastatic Non-small Cell Lung Cancer
Where
Hobart, Woolloongabba
Age
18 years and over
People
830 worldwide
Run by
AstraZeneca
See details and how to joinNCT06868277 · EU 2024-517780-24-00
Phase 1/2Taking people
Evaluation of XYA02 in Patients With Advanced Solid Tumors
Where
Melbourne, Perth, Sydney
Age
18 years and over
People
190
Run by
XYone Therapeutics, Inc
See details and how to joinNCT07670312
Phase 1/2Taking people
A Study of Zidesamtinib (NVL-520) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ROS1 Rearrangement (ARROS-1)
Where
Camperdown, Melbourne
Age
12 years and over
People
359 worldwide
Run by
Nuvalent Inc.
See details and how to joinNCT05118789 · EU 2024-511793-71-00
Phase 1Taking people
A Study of KIVU-107 in Participants With Locally Advanced or Metastatic Solid Tumors
Where
Adelaide, Brisbane, Camperdown, Geelong, Sydney
Age
18 years and over
People
76 worldwide
Run by
Kivu Bioscience Inc.
See details and how to joinNCT07229313
Phase 1Taking people
A Phase I Dose Escalation and Dose Expansion Study to Investigate the Pharmacokinetics and Safety of Subcutaneous Durvalumab
Where
Fitzroy, St Albans, Woolloongabba
Age
18 years and over
People
40 worldwide
Run by
AstraZeneca
See details and how to joinNCT07391670 · EU 2025-521639-34-00
Phase 1/2Taking people
A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of BMS-986507 Combinations in Adult Participants With Advanced Solid Tumors
Where
Liverpool, Melbourne, Subiaco, Woolloongabba
Age
18 years and over
People
416 worldwide
Run by
Bristol-Myers Squibb
See details and how to joinNCT06618287
Phase 1/2Taking people
Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer
Where
Bedford Park, Clayton, Frankston, Heidelberg, Melbourne, Miranda, Saint Albans
Age
18 years and over
People
159 worldwide
Run by
Aulos Bioscience, Inc.
See details and how to joinNCT05267626
Phase 2Taking people
A Study of Navlimetostat (BMS-986504) Alone or in Combination With Izalontamab Brengitecan in Participants With Pre-treated Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) With Homozygous MTAP Deletion or MTAP Loss (MountainTAP-9)
Where
Adelaide, Campbelltown, Camperdown, Woolloongabba
Age
18 years and over
People
182 worldwide
Run by
Bristol-Myers Squibb
See details and how to joinNCT06855771 · EU 2024-519814-29-00
Phase 1/2Taking people
Study of BPI-572270 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS
Where
Bedford Park, Blacktown, Heidelberg, Nedlands, Randwick, Sydney
Age
18 years and over
People
120 worldwide
Run by
Betta Pharmaceuticals Co., Ltd.
See details and how to joinNCT07435038
Phase 3Taking people
Phase 3 Trial of Tarlatamab (SC vs IV) in Extensive-Stage Small Cell Lung Cancer After Platinum Based First-line Chemotherapy (ES-SCLC)
Where
Elizabeth Vale
Age
18 years to 99 years
People
400 worldwide
Run by
Amgen
See details and how to joinNCT07778316
Phase 1/2Taking people
SL-28 for Advanced Solid Tumours
Where
Adelaide, Gold Coast, Sydney
Age
18 years and over
People
60
Run by
Second Life Therapeutics
See details and how to joinNCT07341737
Phase 1/2Taking people
Safety and Preliminary Effectiveness of BNT317, an Investigational Therapy for Advanced Solid Tumors
Where
Adelaide, Clayton, Randwick, Southport
Age
18 years and over
People
248 worldwide
Run by
BioNTech SE
See details and how to joinNCT06750185
Phase 1Taking people
Open-label Study of BBO-8520 in Adult Subjects With KRASG12C Non-small Cell Lung Cancer
Where
Bedford Park, Darlinghurst, Frankston, Melbourne, Nedlands, Woodville South
Age
18 years and over
People
350 worldwide
Run by
TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics)
See details and how to joinNCT06343402
Phase 1Taking people
A Study to Evaluate KIN-2787 in Participants With BRAF and/or NRAS Mutation Positive Solid Tumors
Where
Heidelberg, Perth, Southport, Waratah, Wollstonecraft
Age
18 years and over
People
400 worldwide
Run by
Pierre Fabre Medicament
See details and how to joinNCT04913285
Phase 1/2Taking people
A Phase 1/2a Study of DB-1303/BNT323 in Advanced/Metastatic Solid Tumors
Where
Melbourne, Randwick, South Brisbane, Sydney
Age
18 years and over
People
796 worldwide
Run by
DualityBio Inc.
See details and how to joinNCT05150691
Phase 1/2Taking people
Study of ECI830 Single Agent or in Combination in Patients With Advanced HR+/HER2- Breast Cancer and in Patients With Other Advanced Solid Tumors
Where
Clayton, Melbourne
Age
18 years to 100 years
People
280 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT06726148 · EU 2024-517281-42-00
Phase 3Taking people
Phase III, Open-label Study of First-line Osimertinib With or Without Datopotamab Deruxtecan for EGFRm Locally Advanced or Metastatic Non-small Cell Lung Cancer
Where
Camperdown, Clayton, Kogarah, South Brisbane, Westmead
Age
18 years and over
People
582 worldwide
Run by
AstraZeneca
See details and how to joinNCT06350097 · EU 2023-509883-89-00
Phase 1/2Taking people
A Clinical Study to Investigate the Efficacy and Safety of an Investigational Combination Therapy With BNT324 and BNT327 in Patients With Advanced Lung Cancer
Where
Bedford Park, Bendigo, Camperdown, Geelong, Saint Albans, Subiaco
Age
18 years and over
People
594 worldwide
Run by
BioNTech SE
See details and how to joinNCT06892548 · EU 2024-520238-31-01
Phase 3Taking people
Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma
Where
Parkville, Perth, Westmead
Age
Up to 50 years
People
62 worldwide
Run by
Children's Oncology Group
See details and how to joinNCT05235165