Lung cancer trials in France

In France 316 Also abroad 2746

316 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 14 November 2026. Ask the study team whether a trial fits you.

Phase 1/2Taking people
A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors
Where
Lyon, Marseille, Paris
Age
18 years and over
People
616 worldwide
Run by
Verastem, Inc.
See details and how to joinNCT07020221
Phase 3Taking people
A Study of GSK5764227 in Participants With Relapsed Small Cell Lung Cancer (SCLC) [EMBOLD SCLC-301]
Where
Boulogne-Billancourt, Grenoble, Saint-Herblain, Villejuif
Age
18 years and over
People
420 worldwide
Run by
GlaxoSmithKline
See details and how to joinNCT07099898
Phase 3Taking people
Phase III Study of Datopotamab Deruxtecan Versus Docetaxel in Previously Treated TROP2-positive Advanced or Metastatic Non-squamous NSCLC Without Actionable Genomic Alterations
Where
Boulogne-Billancourt, Lyon, Marseille, Saint-Herblain, Toulouse
Age
18 years and over
People
400 worldwide
Run by
AstraZeneca
See details and how to joinNCT07291037 · EU 2024-520101-39-00
Phase 3Taking people
DAREON ® -Lung-1: A Study in People With Advanced Small Cell Lung Cancer to Compare Obrixtamig Plus Atezolizumab, Carboplatin, and Etoposide Treatment With Standard Chemoimmunotherapy
Where
Angers, Bordeaux, Caen Cedex 5, Dijon, Marseille, Paris, Saint-Herblain, Toulouse, Villefranche Sur Saone Cedex, Villejuif
Age
18 years and over
People
670 worldwide
Run by
Boehringer Ingelheim
See details and how to joinNCT07472517 · EU 2025-520565-51-00
Phase 3Taking people
Study of Izalontamab Brengitecan (BMS-986507) in Combination With Osimertinib Versus Osimertinib Monotherapy or Osimertinib in Combination With Platinum-based Chemotherapy for EGFRmt Non-small Cell Lung Cancer (IZABRIGHT-Lung02)
Where
Bron, Caen Cedex 5, Dijon, Grenoble Cedex 9, Lyon, Marseille, Paris, Quimper Cedex, Saint-Herblain, Toulouse, Villejuif
Age
18 years and over
People
850 worldwide
Run by
Bristol-Myers Squibb
See details and how to joinNCT07680790 · EU 2026-526486-21-00
Phase 1/2Taking people
A Study of DS-3939a in Participants With Solid Tumors
Where
Marseille, Montpellier, Paris, Rennes, Saint-Herblain, Suresnes, Vandœuvre-lès-Nancy, Villejuif
Age
18 years and over
People
400 worldwide
Run by
Daiichi Sankyo
See details and how to joinNCT07739966 · EU 2026-525218-75-00
Phase 1/2Taking people
A Study to Test Obrixtamig in Combination With Pumitamig in People With Advanced Small Cell Lung Cancer (Dareon®-Rosetta35)
Where
Lyon, Marseille, Villejuif Cedex
Age
18 years and over
People
55 worldwide
Run by
Boehringer Ingelheim
See details and how to joinNCT07843940 · EU 2026-525459-99-00
Phase 1Not yet taking people in France
A Study of LY4336619 in Adult Participants With Advanced Solid Tumors
Where
Lyon, Saint-Herblain, Toulouse, Villejuif
Age
18 years and over
People
370 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07928258 · EU 2026-526553-33-00
No phaseTaking people
Analysis of Circulating Tumor Markers in Blood
Where
Montpellier
Age
18 years and over
People
992
Run by
Institut du Cancer de Montpellier - Val d'Aurelle
See details and how to joinNCT04025541
Phase 3Taking people
A Study to Compare the Efficacy of Nivolumab and Relatlimab Plus Chemotherapy vs Pembrolizumab Plus Chemotherapy for Stage IV/Recurrent Non-squamous Non-small Cell Lung Cancer With PD-L1 Expression ≥ 1%
Where
Avignon, Bayonne, Bordeaux Cedex, Brest Cedex 2, Dijon, Le Mans Cedex 9, Lille, Marseille, Paris, Pierre-Bénite, Toulon, Toulouse, Vandoeuvre Les Nancy Cedex
Age
18 years and over
People
1,000 worldwide
Run by
Bristol-Myers Squibb
See details and how to joinNCT06561386 · EU 2024-513682-40-01
Phase 3Taking people
A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)
Where
Caen, Lille, Lyon, Paris Cedex 13, Saint-Herblain Cedex, Tours, Villejuif
Age
18 years and over
People
680 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT06623422 · EU 2023-506327-29-00
Phase 1/2Taking people
A Clinical Study of Gocatamig (MK-6070) and Infinatamab Deruxtecan (MK-2400) in People With Small Cell Lung Cancer (MK-6070-003)
Where
Brest, Bron, Grenoble Cedex 9, Limoges
Age
18 years to 64 years
People
170 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT07227597 · EU 2025-521032-11-00
Phase 2Taking people
Beamion 44: A Study to Test How Well Zongertinib is Tolerated by People With Advanced Non-small Cell Lung Cancer With HER2 Mutations When Given in Combination With Chemotherapy With or Without Pembrolizumab
Where
Lyon, Paris
Age
18 years and over
People
60 worldwide
Run by
Boehringer Ingelheim
See details and how to joinNCT07486817 · EU 2025-523567-38-00
Phase 3Taking people
A Clinical Trial of Adjuvant Intismeran (V940) With or Without Pembrolizumab Coformulated With Berahyaluronidase Alfa (MK-3475A) in High-Risk Stage I Non-Small Cell Lung Cancer (V940-014)
Where
Clermont-Ferrand, Dijon, Paris, Pessac, Rennes, Suresnes, Toulouse, Vandoeuvre Les Nancy
Age
18 years and over
People
876 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT07513376 · EU 2025-522643-18-00
Phase 3Taking people
A Study to Evaluate the Efficacy and Safety of Divarasib Compared With Investigator's Choice of Immunotherapy or Observation in Participants With Resected Stage II-III KRAS G12C-Positive Non-Small Cell Lung Cancer (NSCLC)
Where
Avignon, Bron, Caen Cedex 5, Clermont Ferrand Cedex 1, Lyon, Montpellier Cedex 5, Quimper Cedex, Reims Cedex, Saint-Herblain, Strasbourg Cedex, Suresnes, Villejuif
Age
18 years and over
People
400 worldwide
Run by
Hoffmann-La Roche
See details and how to joinNCT07541170 · EU 2025-524263-21-01
Phase 3Taking people
A Study to Compare Setidegrasib (ASP3082) With Docetaxel, in People With Non-small Cell Lung Cancer With a KRAS G12D Mutation
Where
Avignon Cedex 9, Boulogne-Billancourt, Bron, Caen Cedex 5, Caen Cedex 9, Créteil, Dijon, Le Mans Cedex 9, Lyon, Lyon Cedex 04, Marseille, Nice Cedex 2, Paris, Pessac, Pierre-Bénite, Quimper Cedex, Rennes, Saint-Herblain, Saint-Herblain Cedex, Suresnes, Valenciennes, Villefranche Sur Saone Cedex, Villejuif
Age
18 years and over
People
356 worldwide
Run by
Astellas Pharma Global Development, Inc.
See details and how to joinNCT07566052 · EU 2025-524079-22-00
Phase 1/2Taking people
A Study of Neladalkib (NVL-655) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ALK Rearrangement or Activating ALK Mutation (ALKOVE-1)
Where
Lyon, Saint-Herblain, Toulouse Cedex 9, Villejuif
Age
12 years and over
People
840 worldwide
Run by
Nuvalent Inc.
See details and how to joinNCT05384626 · EU 2024-514266-39-00
Phase 3Taking people
A Study to Evaluate the Benefit of Adding Durvalumab After Chemotherapy, Durvalumab and Surgery in Patients With Early-stage, Operable, Non-small Cell Lung Cancer.
Where
Angers, Bordeaux, Le Mans Cedex 9, Lyon, Vantoux
Age
18 years and over
People
290 worldwide
Run by
ETOP IBCSG Partners Foundation
See details and how to joinNCT06284317 · EU 2023-508773-82-00
Phase 3Taking people
Study of Daraxonrasib (RMC-6236) in Patients With RAS Mutated NSCLC (RASolve 301)
Where
Bordeaux, Brest, Bron, Creteil Cedex, Grenoble Cedex 9, Lille, Lyon, Marseille, Montpellier Cedex 5, Paris, Paris Cedex 18, Rennes Cedex 9, Saint-Herblain, Saint-Herblain Cedex, Strasbourg Cedex, Toulouse, Villejuif
Age
18 years and over
People
590 worldwide
Run by
Revolution Medicines, Inc.
See details and how to joinNCT06881784 · EU 2024-518154-16-00
No phaseTaking people
Analysis of Circulating Tumor Markers in Blood - ALCINA 5
Where
Montpellier
Age
18 years and over
People
620
Run by
Institut du Cancer de Montpellier - Val d'Aurelle
See details and how to joinNCT07060950
No phaseTaking people
Development of Clinical and Biological Database on Bronchial Cancer
Where
Montpellier
Age
18 years and over
People
750
Run by
Institut du Cancer de Montpellier - Val d'Aurelle
See details and how to joinNCT07085429
Phase 1/2Taking people
A Study of VRN110755 in Patients With EGFR-Mutant Non-Small Cell Lung Cancer
Where
Dijon, Marseille
Age
18 years and over
People
315 worldwide
Run by
Voronoi, Inc
See details and how to joinNCT07699328 · EU 2025-523122-40-00
No phaseNot yet taking people in France
PROMETHEE: A Shared Interregional Tele-Tobacco Cessation Platform Embedded Within the IMPULSION Lung Cancer Screening Program
Where
Pierre-Bénite
Age
50 years to 74 years
People
5,400
Run by
Hospices Civils de Lyon
See details and how to joinNCT07921719
Phase 3Taking people
A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer
Where
Angers, Bobigny, Bron, Caen, Lyon, Montpellier, Nice, Paris, Pessac, Reims, Saint-Quentin, Strasbourg, Vannes
Age
18 years and over
People
600 worldwide
Run by
Hoffmann-La Roche
See details and how to joinNCT06793215
Phase 3Taking people
First-line Immunotherapy-based Standard of Care and Local Ablative Treatments for Oligometastatic Non-small Cell Lung Cancer Patients.
Where
Avignon, Caen, Creil, Lille, Lyon, Nice, Nîmes, Paris, Saint-Cloud, Tarbes, Villejuif
Age
18 years and over
People
124
Run by
Gustave Roussy, Cancer Campus, Grand Paris
See details and how to joinNCT06840782