Lung cancer trials in France

In France 316 Also abroad 2746

316 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 15 November 2026. Ask the study team whether a trial fits you.

Phase 2Taking people
Study of pre- and post-surgery treatment with IPH5201 and durvalumab in participants with lung cancer (MATISSE)
Where
Lille, Limoges Cedex 1, Lyon, Marseille, Rennes, Villejuif
Age
18 years to 64 years
People
69 worldwide
Run by
Innate Pharma
See details and how to join2023-507778-42-00
No phaseTaking people
Pilot Study of the Contribution of Fractional Exhaled Nitric Oxide as a Prognostic Marker of Response to Anti-PD-L1 Immunotherapy in Non-small Cell Lung Cancer
Where
Dijon
Age
18 years and over
People
56
Run by
Centre Hospitalier Universitaire Dijon
See details and how to joinNCT05985330
Phase 1/2Taking people
Clinical Trial Evaluating the Safety and Efficacy of Chemoimmunotherapy Plus Short Course of Mek Inhibitor in First Line of Treatment of Metastatic Non Squamous Non Small Cell Lung Adenocarcinoma With PDL1 < 50 %.
Where
Dijon
Age
18 years and over
People
24
Run by
Centre Georges Francois Leclerc
See details and how to joinNCT05937906
No phaseTaking people
Performance of Lung MRI Combined to Synthetic CT in the Follow-up of Lung Nodules
Where
Pessac
Age
55 years to 74 years
People
50
Run by
University Hospital, Bordeaux
See details and how to joinNCT06825078
Phase 1/2Not yet taking people in France
A Study of IDE849 in Patients With DLL3 Expressing Tumors Including Small Cell Lung Cancer
Where
Marseille, Toulouse Cedex 9, Villejuif
Age
18 years and over
People
262 worldwide
Run by
IDEAYA Biosciences
See details and how to joinNCT07174583 · EU 2025-523438-24-00
Phase 2Taking people
Phase II Efficacy Study of Repotrectinib in Frail and/or Elderly Patients With ROS1-rearranged Advanced NSCLC
Where
Aix En Provence, Angers, Brest, Bron, Caen Cedex 5, Chambéry, Colmar Cedex, Creteil Cedex, La Roche Sur Yon Cedex 9, Lille, Limoges Cedex 1, Marseille, Pessac, Quimper Cedex, Rennes, Rouen Cedex, Suresnes, Toulon Cedex 9, Toulouse, Villefranche Sur Saone Cedex
Age
18 years and over
People
30
Run by
Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
See details and how to joinNCT06552234 · EU 2023-509073-23-00
Phase 1Taking people
A Study of Sigvotatug Vedotin in Advanced Solid Tumors
Where
Angers, Nice Cedex 2, Poitiers, Vandouvre Les Nancy, Villejuif
Age
18 years and over
People
1,006 worldwide
Run by
Seagen, a wholly owned subsidiary of Pfizer
See details and how to joinNCT04389632 · EU 2023-508469-34-00
Phase 1/2Taking people
A Study to Investigate ALE.P03 as Monotherapy in Adult Patients With Selected Advanced or Metastatic CLDN1+ Solid Tumors
Where
Dijon, Marseille, Toulouse, Villejuif
Age
18 years and over
People
180 worldwide
Run by
Alentis Therapeutics AG
See details and how to joinNCT07169734 · EU 2025-521441-24-00
Phase 1/2Taking people
PHASE IB/II CLINICAL TRIAL EVALUATING THE SAFETY AND EFFICACY OF CHEMOIMMUNOTHERAPY PLUS SHORT COURSE OF MEK INHIBITOR IN FIRST LINE OF TREATMENT OF METASTATIC NON SQUAMOUS NON SMALL CELL LUNG ADENOCARCINOMA WITH PDL1 <50%
Where
Dijon
Age
18 years and over
People
102
Run by
Centr Georges Francois Leclerc
See details and how to join2023-508477-87-00
Phase 2Taking people
Single Arm Study of WSD0922-FU for NSCLC Patients with C797S mutation
Where
Caen Cedex 5, Limoges, Pessac, Rennes Cedex 9, Toulon Cedex
Age
18 years and over
People
10
Run by
Wayshine Biopharm Inc.
See details and how to join2024-519713-65-00
Phase 2Taking people
Autologous LN-145 in Patients With Metastatic Non-Small-Cell Lung Cancer
Where
Amiens Cedex 1, Clermont-Ferrand, Marseille, Nancy Cedex, Nice, Pierre-Bénite, Poitiers, Saint-Herblain, Villejuif
Age
18 years to 70 years
People
170 worldwide
Run by
Iovance Biotherapeutics, Inc.
See details and how to joinNCT04614103 · EU 2024-510778-26-00
Early phase 1Not yet taking people in France
Evaluation of the Value of [68Ga]Ga-PENTIXAFOR PET-CT in Patients With Metastatic Small Cell Lung Cancer (SCLC)
Where
Angers, Saint-Herblain Cedex
Age
18 years and over
People
15
Run by
Institut Cancerologie de l'Ouest
See details and how to joinNCT07007325 · EU 2024-514057-30-00
Phase 2Taking people
IPH5201 and Durvalumab in Patients With Resectable Non-Small Cell Lung Cancer (MATISSE)
Where
Angers, Caen, Lille, Limoges, Lyon, Marseille, Rennes, Rouen, Villejuif
Age
18 years and over
People
70 worldwide
Run by
Innate Pharma
See details and how to joinNCT05742607
No phaseTaking people
Impact of Respiratory Rehabilitation on Quality of Life in Patients With Metastatic Non-small Cell Lung Cancer Treated With Immunotherapy and Chemotherapy in the Maintenance Phase
Where
Brest, Morlaix, Quimper
Age
18 years and over
People
96
Run by
University Hospital, Brest
See details and how to joinNCT06441773
Phase 2Taking people
A randomized multicenter Phase II trial evaluating oral pooled fecal microbiotherapy (MaaT033) concomitant to Cemiplimab (CB) versus best investigator’s choice (BIC) in resistance to PD-1/PD-L1 blockade due to antibiotics (ATB) uptake in patients with advanced non-small cell lung cancer (NSCLC) - IMMUNOLIFE2
Where
Aix En Provence, Beuvry, Bordeaux, Dijon, Grenoble Cedex 9, Marseille, Nice Cedex 2, Paris, PARIS, Paris Cedex 18, Suresnes, Toulon, Villejuif
Age
18 years to 64 years
People
162
Run by
Institut Gustave Roussy
See details and how to join2024-517018-14-00
No phaseTaking people
Hybrid Prehabilitation Before Thoracic Surgery
Where
Rouen
Age
18 years and over
People
38
Run by
ADIR Association
See details and how to joinNCT06866717
No phaseTaking people
Implementing Low-dose ct Lung Cancer Screening in France.
Where
Lyon, Paris
Age
50 years to 74 years
People
20,000
Run by
Assistance Publique - Hôpitaux de Paris
See details and how to joinNCT07513818
Phase 1/2Completed
A Study to Evaluate the Safety, Tolerability, and Efficacy of MORAb-202 (Herein Referred to as Farletuzumab Ecteribulin), a Folate Receptor Alpha (FRα)-Targeting Antibody-drug Conjugate (ADC) in Participants With Selected Tumor Types
Where
Bayonne, Caen Cedex 5, Lille, Lyon, Marseille, Nice Cedex 2, Paris, St Herblain, Strasbourg, Villejuif
Age
18 years and over
People
182 worldwide
Run by
Eisai Inc.
See details and how to joinNCT04300556 · EU 2023-506868-14-00
Phase 1Taking people
Study With ABBV-CLS-484 in Participants With Locally Advanced or Metastatic Tumors
Where
Marseille, Nice, Suresnes, Toulouse
Age
18 years and over
People
248 worldwide
Run by
Calico Life Sciences LLC
See details and how to joinNCT04777994 · EU 2023-507568-38-00
Phase 1/2Taking people
Dose-finding and Dose Expansion Study of OSE-279 in Subjects With Advanced Solid Tumors or Lymphomas
Where
Lyon, Montpellier Cedex 5, Paris, Rennes Cedex, Saint-Herblain Cedex, Toulouse, Villejuif
Age
18 years and over
People
41 worldwide
Run by
OSE Immunotherapeutics
See details and how to joinNCT05751798 · EU 2024-514826-22-00
Phase 2Not yet taking people in France
Phase II Study of Upfront SRT Plus Ivonescimab/Chemotherapy vs Ivonescimab/Chemotherapy in NSCLC Brain Mets
Where
Clermont-Ferrand, Lyon, Nice Cedex 2, Reims, Villejuif
Age
18 years and over
People
158 worldwide
Run by
European Organisation for Research and Treatment of Cancer - EORTC
See details and how to joinNCT07234877 · EU 2025-522985-60-00
Phase 1/2Not yet taking people in France
A clinical trial to learn more about the effects of DJI136 in people with extensive-stage small cell lung cancer
Where
Lille, Marseille, Pierre-Bénite
Age
18 years and over
People
25 worldwide
Run by
Novartis Pharma AG
See details and how to join2025-523276-23-00
Phase 2Taking people
Niraparib Added to Anti-PD-L1 Antibody Maintenance in SLFN11-positive, Extensive-disease SCLC
Where
Angers, Avignon, Caen Cedex 9, Lyon
Age
18 years and over
People
44 worldwide
Run by
ETOP IBCSG Partners Foundation
See details and how to joinNCT05718323 · EU 2022-502092-33-00
No phaseTaking people
Prospective Cohort Study Evaluating 18FDG PET-CT for the Early Prediction of the Efficacy of Immunotherapy Associated or Not With Chemotherapy in Patients With Locally Advanced or Metastatic Non-Small Cell Broncho-Pulmonary Carcinoma
Where
Nice
Age
18 years and over
People
200
Run by
Centre Antoine Lacassagne
See details and how to joinNCT06833229
Phase 1/2Active, not recruiting
A Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 Rearrangements
Where
Dijon, Grenoble Cedex 9, Nice Cedex 2, Villejuif
Age
12 years and over
People
500 worldwide
Run by
Turning Point Therapeutics, Inc.
See details and how to joinNCT03093116 · EU 2024-512606-25-00