Lung cancer: open trials in Malaysia

24 open trials have a site in Malaysia. Registry data; only the trial team decides who can take part.

NCT05920356
A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202)
Trial Treatment · Phase 3 · Amgen
University Malaya Medical Centre, Kuala Lumpur · Pantai Hospital Kuala Lumpur, Kuala Lumpur · Hospital Tengku Ampuan Afzan, Kuantan
Registry updated 2026-11-06
NCT07699328
A Study of VRN110755 in Patients With EGFR-Mutant Non-Small Cell Lung Cancer
Trial Treatment · Phase 1/2 · Voronoi, Inc
Hospital Kuala Lumpur, Kuala Lumpur · University Malaya Medical Centre, Kuala Lumpur · Hospital Umum Sarawak, Kuching · Institut Kanser Negara, Putrajaya
Registry updated 2026-11-06
NCT06452277
A Study to Learn More About How Well Sevabertinib Works and How Safe it is Compared With Standard Treatment, in Participants Who Have Advanced Non-small Cell Lung Cancer (NSCLC) With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)
Trial Treatment · Phase 3 · Bayer
University Hospital Kebangsaan Malaysia, Cheras · Gleneagles Penang Medical Center, George Town · Universiti Malaya Medical Centre, Kuala Lumpur · Sunway Medical Centre Penang, Perai · Beacon Hospital, Petaling Jaya · Columbia Asia Hospital Bukit Rimau, Shah Alam · Sunway Medical Centre, Subang Jaya
Registry updated 2026-11-04
NCT06706076
A Study of BH-30643 in Subjects With Locally Advanced or Metastatic NSCLC Harboring EGFR and/or HER2 Mutations
Trial Treatment · Phase 1/2 · BlossomHill Therapeutics
Sarawak General Hospital, Kuching
Registry updated 2026-11-04
NCT05498428
A Study of Amivantamab in Participants With Advanced or Metastatic Solid Tumors Including Epidermal Growth Factor Receptor (EGFR)-Mutated Non-Small Cell Lung Cancer
Trial Treatment · Phase 2 · Janssen Research & Development, LLC
University Malaya Medical Centre, Kuala Lumpur · Hospital Tengku Ampuan Afzan, Kuantan · Hospital Umum Sarawak, Kuching · Beacon Hospital Sdn Bhd, Petaling Jaya
Registry updated 2026-11-03
NCT07185997
Study to Evaluate Efficacy and Safety of Firmonertinib Compared With Investigator's Choice of EGFR Inhibitor as First-Line Treatment in Participants Who Have Locally Advanced or Metastatic NSCLC With EGFR P-Loop and Alpha C-Helix Compressing (PACC) Uncommon Mutations
Trial Treatment · Phase 3 · ArriVent BioPharma, Inc.
Hospital Kuala Lumpur, Kuala Lumpur · OncoCar Cancer Centre, Petaling Jaya
Registry updated 2026-11-02
NCT04613596
Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7
Trial Treatment · Phase 2/3 · Mirati Therapeutics Inc.
Local Institution - Unk048, George Town · Hospital Pulau Pinang, George Town · Gleneagles Penang, George Town · Local Institution - Unk079, Johor Bahru · Hospital Kuala Lumpur, Kuala Lumpur · Local Institution - Unk075, Kuala Lumpur · Sunway Medical Centre - Sunway City, Petaling Jaya · Local Institution - Unk007, Petaling Jaya
Registry updated 2026-10-30
NCT06692738
A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Squamous Non-small Cell Lung Cancer (NSCLC)
Trial Treatment · Phase 3 · AstraZeneca
George Town · Johor Bahru · Kuala Lumpur
Registry updated 2026-10-29
NCT06627647
A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Non-Squamous NSCLC
Trial Treatment · Phase 3 · AstraZeneca
Kuala Lumpur · Kuching · Petaling Jaya
Registry updated 2026-10-28
NCT06996782
A Platform Study in Non-Small Cell Lung Cancer (NSCLC)
Trial Treatment · Phase 1/2 · AstraZeneca
Kuala Lumpur · Kuala Selangor · Kuching · Singapore
Registry updated 2026-10-28
NCT07472517
DAREON ® -Lung-1: A Study in People With Advanced Small Cell Lung Cancer to Compare Obrixtamig Plus Atezolizumab, Carboplatin, and Etoposide Treatment With Standard Chemoimmunotherapy
Trial Treatment · Phase 3 · Boehringer Ingelheim
Hospital Pulau Pinang-Georgetown, Pulau Pinang-40766, George Town · Hospital Wanita Dan Kanak-Kanak Sabah, Kota Kinabalu · Sarawak General Hospital, Kuching · National Cancer Institute (IKN), Putrajaya · Sunway Medical Centre, Selangor Darul Ehsan
Registry updated 2026-10-28
NCT07190248
A Clinical Study of Calderasib (MK-1084) and Other Treatments for Participants With Non-Small Cell Lung Cancer (MK-1084-007/KANDLELIT-007)
Trial Treatment · Phase 3 · Merck Sharp & Dohme LLC
Hospital Pulau Pinang (Site 3108), George Town · Sultan Ismail Hospital (Site 3103), Johor Bahru · Hospital Wanita and Kanak Kanak Sabah (Site 3110), Kota Kinabalu · Cengild G.I. Medical Centre (Site 3112), Kuala Lumpur · Hospital Tengku Ampuan Afzan (Site 3109), Kuantan · Sarawak General Hospital (Site 3101), Kuching · Sunway Medical Centre (Site 3106), Petaling Jaya · University Malaya Medical Centre (Site 3107), Wilayah Persekutuan
Registry updated 2026-10-26
NCT06899126
Study of Trastuzumab Deruxtecan, Pembrolizumab, and Platinum-based Chemotherapy in First-line HER2 Overexpressing Non-small Cell Lung Cancer
Trial Treatment · Phase 3 · Daiichi Sankyo
Gleneagles Hospital Penang, Jalan Pangkor · Hospital Kuala Lumpur, Kuala Lumpur · Hospital Tengku Ampuan Afzan, Kuantan · Beacon Hospital Sdn Bhd, Petaling Jaya
Registry updated 2026-10-23
NCT07063745
A Study to Compare the Combination of Navlimetostat (BMS-986504) With Pembrolizumab and Chemotherapy Versus Placebo Plus Pembrolizumab and Chemotherapy in First-line Metastatic Non-small Cell Lung Cancer Participants With Homozygous MTAP Deletion
Trial Treatment · Phase 2/3 · Bristol-Myers Squibb
Sarawak General Hospital, Kuching · University Malaya Medical Centre, Lembah Pantai
Registry updated 2026-10-23
NCT07361510
A Study to Evaluate the Efficacy of Pumitamig Versus Pembrolizumab in Participants With Previously Untreated Advanced Non-Small Cell Lung Cancer and PD-L1 ≥ 50%. (ROSETTA Lung-202)
Trial Treatment · Phase 3 · Bristol-Myers Squibb
George Town · Kuala Lumpur · Kuching
Registry updated 2026-10-23
NCT06801834
Study of Sacituzumab Govitecan Versus Standard of Care in Participants With Previously Treated Extensive Stage Small Cell Lung Cancer
Trial Treatment · Phase 3 · Gilead Sciences
Pantai Hospital Kuala Lumpur, Kuala Lumpur · Beacon Hospital, Kuala Selangor · Sunway Medical Centre, Kuala Selangor · Sarawak General Hospital, Kuching · University Malaya Medical Centre, Lembah Pantai
Registry updated 2026-10-20
NCT06646276
A Study to Compare the Efficacy and Safety of BMS-986489 (Atigotatug+ Nivolumab Fixed Dose Combination) in Combination With Carboplatin Plus Etoposide to That of Atezolizumab With Carboplatin Plus Etoposide as First-Line Therapy in Participants With Extensive-Stage Small Cell Lung Cancer (TIGOS).
Trial Treatment · Phase 3 · Bristol-Myers Squibb
Kuala Lumpur · Kuala Lumpur · Kuching
Registry updated 2026-10-13
NCT07128199
A Study to Assess Zipalertinib Versus Placebo in Participants With Early Stage NSCLC With Uncommon EGFR Mutations, Following Complete Tumor Resection
Trial Treatment · Phase 3 · Taiho Oncology, Inc.
Hospital Raja Perempuan Zainab II, Kota Bharu · Hospital Kuala Lumpur, Kuala Lumpur · Hospital Picaso, Petaling Jaya · Hospital Pulau Pinang, Pulau Pinang · Sunway Medical Centre, Selangor Darul Ehsan
Registry updated 2026-10-13
NCT06765109
Neladalkib (NVL-655) for TKI-naive Patients With Advanced ALK-Positive NSCLC
Trial Treatment · Phase 3 · Nuvalent Inc.
Hospital Pulau Pinang, George Town · Hospital Kuala Lumpur, Kuala Lumpur · Hospital Umum Sarawak, Kuching · Beacon International Specialist Centre, Petaling Jaya · Institut Kanser Negara, Putrajaya · Sunway Medical Centre, Subang Jaya
Registry updated 2026-09-30
NCT06868277
A Global Phase III Study of Rilvegostomig or Pembrolizumab Monotherapy for First-Line Treatment of PD-L1-high Metastatic Non-small Cell Lung Cancer
Trial Treatment · Phase 3 · AstraZeneca
George Town · Kota Bharu · Kuala Lumpur · Kuala Selangor · Perai
Registry updated 2026-09-25
NCT07369596
Impact of Chemotherapy Dose Reductions on Survival Outcomes Among Older NSCLC Patients Without Actionable Mutations
Research · University of Malaya
Hospital Wanita Dan Kanak-Kanak Sabah, Kota Kinabalu · Universiti Malaya Medical Centre, Kuala Lumpur · Hospital Tengku Ampuan Afzan, Kuantan
Registry updated 2026-06-02
NCT04686305
Phase Ib Study of the Safety of T-DXd and Immunotherapy Agents With and Without Chemotherapy in Advanced or Metastatic HER2+, Non-squamous NSCLC
Trial Treatment · Phase 1 · AstraZeneca
George Town · Kuala Lumpur · Kuala Selangor · Kuching
Registry updated 2026-04-13
NCT07050043
Low Dose Nivolumab With Chemotherapy vs Standard Chemotherapy as First-Line Treatment in Advanced or Metastatic NSCLC
Trial Treatment · Phase 3 · Dr Arvindran A/L Alaga
Hospital Sultanah Bahiyah, Alor Star
Registry updated 2025-07-03
NCT06504927
Biomarker Discovery in Lung Cancer - Malaysia
Research · University of Malaya
University of Malaya Medical Centre, Kuala Lumpur
Registry updated 2024-07-18

All Lung cancer trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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