Lung cancer: open trials in Puerto Rico

27 open trials have a site in Puerto Rico. Registry data; only the trial team decides who can take part.

NCT07090499
A Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced Solid Tumors
Trial Treatment · Phase 1 · Pfizer
Pan American Center for Oncology Trials LLC, Rio Piedras
Registry updated 2026-11-05
NCT07144280
A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC)
Trial Treatment · Phase 3 · Pfizer
Ad-Vance Medical Research, Ponce
Registry updated 2026-11-05
NCT07519655
Phase 1 Study of PF-08046033 in Advanced Solid Tumors
Trial Treatment · Phase 1 · Pfizer
Hospital Oncologico Dr. Isaac Gonzalez-Martinez, Rio Piedras · Pan American Center for Oncology Trials LLC, Rio Piedras
Registry updated 2026-11-05
NCT03556228
VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma
Trial Treatment · Phase 1/2 · VM Oncology, LLC
PanOncology Trials, Hospital Oncologico - Puerto Rico Medical Center, Río Piedras (site 200), San Juan
Registry updated 2026-11-04
NCT06418204
Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics
Research · Wake Forest University Health Sciences
Doctors Cancer Center, Manati · Centro Comprensivo de Cancer de UPR, San Juan · PROncology, San Juan
Registry updated 2026-11-04
NCT07659782
A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Non-Small Cell Lung Cancer
Trial Treatment · Phase 2 · Verastem, Inc.
BRCR Global- San Juan, San Juan · BRCR Global- Yauco, Yauco
Registry updated 2026-11-04
NCT06667076
A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
Trial Treatment · Phase 2 · Janssen Research & Development, LLC
Auxilio Mutuo Cancer Center, San Juan
Registry updated 2026-11-03
NCT06692738
A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Squamous Non-small Cell Lung Cancer (NSCLC)
Trial Treatment · Phase 3 · AstraZeneca
San Juan
Registry updated 2026-10-29
NCT06357533
Phase III, Open-label, Study of First-line Dato-DXd in Combination With Rilvegostomig for Advanced Non-squamous NSCLC With High PD-L1 Expression (TC ≥ 50%) and Without Actionable Genomic Alterations
Trial Treatment · Phase 3 · AstraZeneca
San Juan
Registry updated 2026-10-28
NCT06627647
A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Non-Squamous NSCLC
Trial Treatment · Phase 3 · AstraZeneca
San Juan
Registry updated 2026-10-28
NCT07109726
A Phase 1/2 Trial of TER-2013 in Patients With Solid Tumors Harboring AKT/PI3K/PTEN Pathway Alterations
Trial Treatment · Phase 1/2 · Terremoto Biosciences Inc.
PanOncology Trials, San Juan
Registry updated 2026-10-28
NCT06772623
Study to Evaluate Adverse Events and Efficacy of Intravenous (IV) Telisotuzumab Adizutecan in Combination With a PD-1 Immune Checkpoint Inhibitor in Adult Participants With Advanced or Metastatic Non-Squamous NSCLC With No Prior Treatment for Advanced Disease, and No Actionable Genomic Alterations
Trial Treatment · Phase 1/2 · AbbVie
Pan American Center for Oncology Trials - Rio Piedras /ID# 268827, Rio Piedras
Registry updated 2026-10-27
NCT05920356
A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202)
Trial Treatment · Phase 3 · Amgen
Pan American Center for Oncology Trials, Ponce
Registry updated 2026-10-23
NCT07756645
A Study to Assess Intravenous ABBV-1480 Combined With Chemotherapy Versus Pembrolizumab Combined With Chemotherapy for the First Line Treatment of Locally Advanced/Metastatic Non-Small Cell Lung Cancer in Adult Participants
Trial Treatment · Phase 3 · AbbVie
Pan American Center for Oncology Trials - Rio Piedras /ID# 284017, Rio Piedras
Registry updated 2026-10-20
NCT07222566
Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer
Trial Treatment · Phase 3 · Pfizer
Pan American Center for Oncology Trials, LLC - Bayamón Office, Bayamón · Pan American Center for Oncology Trials, LLC- Dorado Office, Dorado · Pan American Center for Oncology Trials, LLC - Manati Office, Manati · Pan American Center for Oncology Trials, LLC - Mayaguez Office, Mayagüez · BRCR Global Puerto Rico - Hato Rey, San Juan
Registry updated 2026-10-08
NCT07226999
Symbiotic-Lung-04: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Extensive-Stage Small Cell Lung Cancer
Trial Treatment · Phase 2/3 · Pfizer
Doctor's Center Hematology & Oncology Group, Manati · Pan American Center for Oncology Trials, LLC - Mayaguez Office Mayaguez Medical Center, Mayagüez · Pan American Center for Oncology Trials LLC, San Juan · Hospital Oncologico Dr. Isaac Gonzalez-Martinez, San Juan
Registry updated 2026-10-08
NCT07227298
Symbiotic-Lung-20: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Different Anticancer Agents in Advanced Cancers
Trial Treatment · Phase 1/2 · Pfizer
Pan American Center for Oncology Trials, LLC - Mayaguez, Mayagüez · Pan American Center for Oncology Trials LLC, Rio Piedras · BRCR Global Puerto Rico - Hato Rey, San Juan
Registry updated 2026-10-08
NCT07489066
Symbiotic-Lung-10: A Study to Learn About PF-08634404 Alone or in Combination in Early-stage or Locally Advanced NSCLC
Trial Treatment · Phase 2 · Pfizer
Pan American Center for Oncology Trials, LLC - Bayamón Office, Bayamón · Pan American Center for Oncology Trials, LLC - Manati Office, Manati · Pan American Center for Oncology Trials, LLC - Ponce Office, Ponce · Hospital Oncologico Dr. Isaac Gonzalez-Martinez, Rio Piedras · Pan American Center for Oncology Trials, LLC - Ciudadela Office, San Juan
Registry updated 2026-10-08
NCT06881784
Study of Daraxonrasib (RMC-6236) in Patients With RAS Mutated NSCLC (RASolve 301)
Trial Treatment · Phase 3 · Revolution Medicines, Inc.
Pan American Center for Oncology Trials, San Juan
Registry updated 2026-09-29
NCT06128551
Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors
Trial Treatment · Phase 1/2 · Revolution Medicines, Inc.
Pan American Center for Oncology Trials, San Juan
Registry updated 2026-09-22
NCT06858813
A Study to Assess Adverse Events and Change in Disease Activity of Intravenously (IV) Infused ABBV-324 in Adult Participants With Hepatocellular Cancer (HCC) or Squamous-Cell Non-Small Cell Lung Cancer (LUSC)
Trial Treatment · Phase 1 · AbbVie
Fdi Clinical Research /ID# 272960, San Juan
Registry updated 2026-09-22
NCT06427941
A Phase 1/2 Study of BGB-B2033, Alone or in Combination With Tislelizumab With or Without Bevacizumab, in Participants With Advanced or Metastatic Solid Tumors
Trial Treatment · Phase 1/2 · BeOne Medicines
Hospital Oncologico, Rio Piedras
Registry updated 2026-09-16
NCT05150691
A Phase 1/2a Study of DB-1303/BNT323 in Advanced/Metastatic Solid Tumors
Trial Treatment · Phase 1/2 · DualityBio Inc.
BRCR Global Puerto Rico LLC., Mayagüez
Registry updated 2026-08-27
NCT06350097
Phase III, Open-label Study of First-line Osimertinib With or Without Datopotamab Deruxtecan for EGFRm Locally Advanced or Metastatic Non-small Cell Lung Cancer
Trial Treatment · Phase 3 · AstraZeneca
Rio Piedras · San Juan
Registry updated 2026-08-26
NCT05235165
Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma
Trial Treatment · Phase 3 · Children's Oncology Group
HIMA San Pablo Oncologic Hospital, Caguas
Registry updated 2026-08-25

All Lung cancer trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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