Lung cancer trials in Spain

In Spain 273 Also abroad 2733

273 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 12 November 2026. Ask the study team whether a trial fits you.

Phase 3Taking people
A Phase III Study With THIO + Cemiplimab vs Chemotherapy as 3rd Line Treatment in Advanced/Metastatic NSCLC
Where
Almería, Badajoz, Badalona, Barcelona, Jaén, Madrid, Málaga, Palma, Valencia
Age
18 years and over
People
300 worldwide
Run by
Maia Biotechnology
See details and how to joinNCT06908304 · EU 2024-520164-33-00
Phase 1/2Not yet taking people in Spain
Phase 1b/2 Trial of OMTX705, an Anti-Fibroblast Activation Protein Antibody-Drug Conjugate, in Combination with Carboplatin, Pemetrexed and Tislelizumab in Patients with Advanced/Metastatic Non-squamous Non-Small Cell Lung Cancer
Where
Barcelona, Fuenlabrada, Jerez de la Frontera, Leganés, Madrid, Málaga, Palma, Santiago de Compostela, Sevilla
Age
18 years to 64 years
People
88
Run by
Oncomatryx Biopharma S.L.
See details and how to join2025-521989-95-00 · EU 2025-521989-95-00
No phaseNot yet taking people in Spain
Neutrophil Biomarker Test for Predicting Clinical Benefit From Immunotherapy Based on Flow Cytometry Analysis
Where
Seville
Age
18 years and over
People
600 worldwide
Run by
OncoHost Ltd.
See details and how to joinNCT07246759
Phase 2Taking people
PALACE: Cemiplimab Trial According to ctDNA Levels
Where
A Coruña, Alicante, Badalona, Barcelona, Bilbao, Elche, Girona, Jerez de la Frontera, Las Palmas De Gran Canaria, Leganés, L'Hospitalet de Llobregat, Madrid, Majadahonda, Málaga, Palma, Salamanca, Valencia
Age
18 years and over
People
63
Run by
Fundación GECP
See details and how to joinNCT06917573 · EU 2024-518812-38-00
Phase 2Taking people
Neoadjuvant Treatment With Atezolizumab and Atezolizumab as Maintenance for the Treatment of Stage III Non Small-Cell Lung Cancer (NSCLC)
Where
A Coruña, Alicante, Badalona, Barcelona, Bilbao, Girona, Granada, Jerez de la Frontera, Las Palmas De Gran Canaria, Lugo, Madrid, Majadahonda, Palma, Pamplona, Reus, Sabadell, Salamanca, Santa Cruz de Tenerife, Sevilla, Valencia
Age
18 years and over
People
97
Run by
Fundación GECP
See details and how to joinNCT07153445 · EU 2024-515984-68-00
No phaseTaking people
Fissios© and Postoperative Complications (FPoC Trial)
Where
Madrid
Age
18 years and over
People
560
Run by
Carlos Alfredo Fraile Olivero, MD, PhD.
See details and how to joinNCT06732193
No phaseTaking people
EMPATHY NSCLC: European Registry for Plasma-Based Molecular Profiling in Advanced NSCLC Patients
Where
Madrid
Age
18 years and over
People
1,000 worldwide
Run by
Hedera Dx SA
See details and how to joinNCT07096258
Phase 1/2Taking people
FIH Trial of VERT-002 in Patients With Locally Advanced or Metastatic Solid Tumors With MET Alterations
Where
Madrid
Age
18 years and over
People
140 worldwide
Run by
Pierre Fabre Medicament
See details and how to joinNCT06669117 · EU 2024-512760-64-00
Phase 2Taking people
APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors
Where
Badalona, Barcelona, L'Hospitalet de Llobregat, Madrid, Valencia
Age
18 years and over
People
497 worldwide
Run by
Apollomics Inc.
See details and how to joinNCT03175224 · EU 2024-514542-37-00
No phaseTaking people
Early Palliative Care in Patients With Advanced Lung Cancer Using an e-Health Ecosystem
Where
Badalona, L'Hospitalet de Llobregat
Age
18 years and over
People
200
Run by
Jesús González
See details and how to joinNCT07039994
Phase 3Taking people
Maintenance Pembrolizumab at Usual or Low doSE in Non-squamous Lung Cancer: a Non-inferiority Study
Where
Barcelona, Madrid, Málaga, Sevilla
Age
18 years and over
People
1,166 worldwide
Run by
Gustave Roussy, Cancer Campus, Grand Paris
See details and how to joinNCT05692999 · EU 2023-503481-23-00
No phaseEnrolling by invitation
Liquid BiOpsy, Lung and Colon Cancer in AndaluciA
Where
Granada
Age
18 years and over
People
500
Run by
Fundación Pública Andaluza para la Investigación Biomédica Andalucía Oriental
See details and how to joinNCT06997458
Phase 1/2Taking people
Cisplatin (CIS) Administered As Dry Powder for Inhalation (DPI) in Patients with Stage IV Non-Small Cell Lung Cancer
Where
Barcelona, Madrid, Seville
Age
18 years and over
People
32 worldwide
Run by
Inhatarget Therapeutics
See details and how to joinNCT06896890
Phase 1Taking people
Study of IBI3009 in Participants with Unresectable, Metastatic or Extensive-Stage Small Cell Lung Cancer
Where
Madrid, Málaga, Sevilla, Valencia
Age
18 years to 75 years
People
190 worldwide
Run by
Innovent Biologics (Suzhou) Co. Ltd.
See details and how to joinNCT06613009 · EU 2025-523972-21-00
Phase 2Taking people
Evaluation of a Pragmatic Approach to Adoptive Cell Therapy (ACT) Using an IL2 Analog (ANV419) vs High Dose IL2 After Tumor Infiltrating Lymphocytes (TIL) Therapy in Patients With Melanoma, NSCLC and Cervical Cancer (PragmaTIL)
Where
Barcelona
Age
18 years and over
People
40
Run by
Vall d'Hebron Institute of Oncology
See details and how to joinNCT06630611
No phaseTaking people
First in Human Study for the Assessment of Safety and Initial Performance of the EAS1 System
Where
Salamanca
Age
18 years to 80 years
People
15 worldwide
Run by
Snipe Medical
See details and how to joinNCT06423690
No phaseTaking people
The Impact of Radiotherapy on Oligometastatic Cancer
Where
Albacete, Barcelona, Castellon, Girona, Granada, Lleida, Madrid, Reus, Seville, Terrassa, Valencia, Zaragoza
Age
18 years and over
People
2,000
Run by
Institut Investigacio Sanitaria Pere Virgili
See details and how to joinNCT05933876
No phaseTaking people
DEPRECAP: Lung Cancer Screening Programme by LDCT for Patients With COPD or Emphysema.
Where
Madrid
Age
55 years to 75 years
People
1,998
Run by
Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
See details and how to joinNCT06690385
No phaseTaking people
High Definition Medicine for Solid Tumors Oncology
Where
A Coruña, Barcelona, Cáceres, Fuenlabrada, Madrid, Palma de Mallorca, Pamplona, Seville, Valencia
Age
18 years and over
People
300
Run by
Centro Nacional de Investigaciones Oncologicas CARLOS III
See details and how to joinNCT06590506
No phaseNot yet taking people in Spain
Understanding Lung Cancer Related Risk Factors and Their Impact
Where
Barakaldo, Seville
Age
40 years to 80 years
People
6,160 worldwide
Run by
Biobizkaia Health Research Institute
See details and how to joinNCT06473870
No phaseTaking people
Registry of the Spanish Society of Thoracic Surgery
Where
Zaragoza
People
30,000
Run by
Sociedad Española de Cirugía Torácica
See details and how to joinNCT05600569
No phaseTaking people
I3LUNG: Integrative Science, Intelligent Data Platform for Individualized LUNG Cancer Care With Immunotherapy
Where
Barcelona
Age
18 years and over
People
2,200 worldwide
Run by
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
See details and how to joinNCT05537922
Phase 1/2Taking people
SPRING Rollover
Where
Barcelona
Age
65 years and over
People
1
Run by
Worldwide Innovative Network
See details and how to join2022-500041-24-00 · EU 2022-500041-24-00