Lung cancer trials in Spain

In Spain 273 Also abroad 2733

273 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 12 November 2026. Ask the study team whether a trial fits you.

Phase 1/2Taking people
First in Human Study of BAY2927088 in Participants Who Have Advanced Non-small Cell Lung Cancer (NSCLC) With Mutations in the Genes of Epidermal Growth Factor Receptor (EGFR) and/or Human Epidermal Growth Factor Receptor 2 (HER2)
Where
Barcelona, L'Hospitalet de Llobregat, Madrid, Valencia
Age
18 years and over
People
430 worldwide
Run by
Bayer
See details and how to joinNCT05099172 · EU 2023-503795-24-00
No phaseTaking people
Telerehabilitation Exercise Program for Postoperative Recovery in Lung Cancer.
Where
Seville
Age
18 years to 80 years
People
56
Run by
University of Seville
See details and how to joinNCT07861282
Phase 3Taking people
Study of Sacituzumab Govitecan Versus Standard of Care in Participants With Previously Treated Extensive Stage Small Cell Lung Cancer
Where
A Coruña, Barcelona, Córdoba, Girona, Jaén, Las Palmas de Gran Canaria, Madrid, Málaga, Seville, Valencia
Age
18 years and over
People
695 worldwide
Run by
Gilead Sciences
See details and how to joinNCT06801834
Phase 3Taking people
A Study to Test How Well ZL-1310 may Work Compared to Therapies Selected by the Investigator in Treating Patients with Relapsed Small Cell Lung Cancer
Where
Badajoz, Badalona, Barcelona, Elche, Girona, Jerez de la Frontera, Lleida, Madrid, Majadahonda, Málaga, Oviedo, Pamplona, Reus, Sevilla, Torrejón de Ardoz, Valencia
Age
18 years and over
People
263 worldwide
Run by
Zai Lab (US) LLC
See details and how to join2025-522818-23-00 · EU 2025-522818-23-00
Phase 1/2Taking people
Study of RAS(ON) Inhibitors in Patients With Advanced RAS-mutated NSCLC
Where
A Coruña, Barcelona, Madrid, Málaga, Pamplona, Pozuelo de Alarcón, Sevilla, Valencia
Age
18 years and over
People
616 worldwide
Run by
Revolution Medicines, Inc.
See details and how to joinNCT06162221 · EU 2025-521147-21-00
Phase 2Taking people
Trial Investigating Visugromab in Combination With Immunochemotherapy in 1L Treatment of Participants With Metastatic NSCLC
Where
Barcelona, Girona, Jaén, Lugo, Madrid, Málaga, Pamplona, Rioja, Santander, Santiago de Compostela, Seville
Age
18 years and over
People
107 worldwide
Run by
CatalYm GmbH
See details and how to joinNCT07098988 · EU 2024-516792-32-01
No phaseTaking people
PRophylactic Cerebral Irradiation or Active MAgnetic Resonance Imaging Surveillance in Small-cell Lung Cancer Patients (PRIMALung Study)
Where
Badajoz, Las Palmas de Gran Canaria, Majadahonda
Age
18 years and over
People
600 worldwide
Run by
European Organisation for Research and Treatment of Cancer - EORTC
See details and how to joinNCT04790253
Phase 1Taking people
A Study of ZL-1310 in Subjects With Small Cell Lung Cancer
Where
Barcelona, Madrid, Málaga, Pozuelo de Alarcón, Seville, Valencia
Age
18 years and over
People
339 worldwide
Run by
Zai Lab (Shanghai) Co., Ltd.
See details and how to joinNCT06179069
Phase 2Taking people
A Study of Pembrolizumab With or Without Chemotherapy in Combination With Additional Treatments for Advanced Non-Small Cell Lung Cancer (NSCLC) (MK-3475-01G/KEYMAKER U01)
Where
Barcelona, L'Hospitalet de Llobregat, Pozuelo de Alarcón
Age
18 years and over
People
90 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT06731907 · EU 2024-515772-12-00
Phase 3Taking people
A Study of ZL-1310 Versus Investigator's Choice of Therapy in Participants With Relapsed Small Cell Lung Cancer (DLLEVATE)
Where
Barcelona, Elche, Girona, Jerez de la Frontera, Madrid, Málaga, Pamplona, Reus, Seville, Valencia
Age
18 years and over
People
480 worldwide
Run by
Zai Lab (Shanghai) Co., Ltd.
See details and how to joinNCT07218146
Phase 1Taking people
A Study of Mevrometostat for Treatment of Relapsed/Refractory SCLC, Castration Resistant Prostate Cancer, and Follicular Lymphoma
Where
Barcelona, Castello De La Plana, L'Hospitalet de Llobregat, Madrid, Málaga, Pozuelo de Alarcón, Valencia
Age
18 years and over
People
453 worldwide
Run by
Pfizer
See details and how to joinNCT03460977 · EU 2023-509179-18-00
No phaseTaking people
Multimodal Prehabilitation in Patients With Lung Cancer Undergoing Neoadjuvant Therapy
Where
Barcelona
Age
18 years and over
People
60
Run by
Hospital Clinic of Barcelona
See details and how to joinNCT05636969
Phase 2Taking people
A Study of Novel Combinations in Non-Small Cell Lung Cancer (NSCLC)
Where
A Coruña, Madrid, Málaga, Manresa, Santander, Valencia
Age
18 years and over
People
278 worldwide
Run by
AstraZeneca
See details and how to joinNCT07098338 · EU 2025-524843-11-00
Phase 3Taking people
BL-M14D1 Plus Atezolizumab vs Standard of Care in First-Line Extensive-Stage Small Cell Lung Cancer (BrenDeLL-Lung01)
Where
A Coruña, Barcelona, Las Palmas de Gran Canaria, Madrid
Age
18 years and over
People
550 worldwide
Run by
SystImmune Inc.
See details and how to joinNCT07625644
No phaseTaking people
A Study to Investigate Treatment Patterns and Effectiveness of Tislelizumab in European Patients With Resectable or Advanced Non-Small Cell Lung Cancer (NSCLC) and Small Cell Lung Cancer (SCLC)
Where
Córdoba, Jaén, Lugo, Segovia, Valencia
Age
18 years and over
People
440
Run by
BeOne Medicines
See details and how to joinNCT07652736
Phase 1Taking people
KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors
Where
Barcelona, Madrid, Sevilla
Age
18 years and over
People
300 worldwide
Run by
Kura Oncology, Inc.
See details and how to joinNCT06026410 · EU 2024-513285-19-00
Phase 3Taking people
Safety and Efficacy of BNT327, an Investigational Therapy in Combination With Chemotherapy for Patients With Untreated Small-cell Lung Cancer
Where
Badajoz, Barcelona, Castello De La Plana, León, Madrid, Málaga, Sevilla, Torrejón de Ardoz, Valencia, Vigo, Zaragoza
Age
18 years and over
People
621 worldwide
Run by
BioNTech SE
See details and how to joinNCT06712355 · EU 2024-515765-34-00
Phase 2Taking people
An Open-Label, Phase 2b, Global Multicenter Cohort Trial to Assess the Safety and Efficacy of Zipalertinib in Patients with Locally Advanced or Metastatic Non-Small Cell Lung Cancer with Exon 20 Insertion and Uncommon/Single or Compound Epidermal Growth Factor Receptor Mutations
Where
A Coruna, Barcelona, Jaén, L'Hospitalet de Llobregat, Madrid, Málaga
Age
18 years and over
People
117 worldwide
Run by
Taiho Oncology Inc.
See details and how to join2023-503865-48-00 · EU 2023-503865-48-00
Phase 2/3Not yet taking people in Spain
IZABRIGHT-Lung01: Study of Izalontamab Brengitecan (BMS-986507) versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer after failure of EGFR TKI Therapy
Where
Barcelona, Madrid, Majadahonda, Málaga, Sevilla, Valencia, Zaragoza
Age
18 years and over
People
173 worldwide
Run by
Bristol-Myers Squibb Services Unlimited Company
See details and how to join2025-521908-22-00 · EU 2025-521908-22-00
Phase 1/2Taking people
A Phase I/IIa Study of AZD8205 Given Alone or Combined, in Participants With Advanced/Metastatic Solid Malignancies
Where
Barcelona, L'Hospitalet de Llobregat, Madrid, Málaga, Pamplona
Age
18 years and over
People
460 worldwide
Run by
AstraZeneca
See details and how to joinNCT05123482 · EU 2022-502759-70-01
Phase 1/2Taking people
Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies
Where
Barcelona, Madrid, Pamplona, Valencia
Age
18 years and over
People
554 worldwide
Run by
Institut de Recherches Internationales Servier
See details and how to joinNCT05786924 · EU 2025-523474-16-00
Phase 3Taking people
A Study to Assess Zipalertinib Versus Placebo in Participants With Early Stage NSCLC With Uncommon EGFR Mutations, Following Complete Tumor Resection
Where
Badalona, Barcelona, Granada, Las Palmas de Gran Canaria, Lugo, Madrid, Majadahonda, Málaga, Palma, Reus, Sabadell, Sevilla, Valencia
Age
18 years and over
People
360 worldwide
Run by
Taiho Oncology, Inc.
See details and how to joinNCT07128199 · EU 2025-521775-31-00
Phase 2Not yet taking people in Spain
A Study to Assess The Safety and Tolerability of Pumitamig-Based Therapy Administered Before Surgery in Participants With Early-Stage Non-Small Cell Lung Cancer (ROSETTA Lung-220)
Where
Barcelona, Majadahonda, Málaga
Age
18 years and over
People
80 worldwide
Run by
Bristol-Myers Squibb
See details and how to joinNCT07871214
Phase 1Taking people
A Study of ZL-1310 in Patients with Small Cell Lung Cancer to Find a Suitable Dose and to Test How Different Doses of ZL-1310 are Tolerated by the Body and How the Body Absorbs, Distributes, Metabolizes and Excretes ZL-1310
Where
Barcelona, Madrid, Málaga, Pozuelo de Alarcón, Sevilla, Valencia
Age
18 years and over
People
80
Run by
Zai Lab (US) LLC
See details and how to join2024-514446-36-00 · EU 2024-514446-36-00
Phase 1Taking people
Study of Elironrasib (RMC-6291) and Daraxonrasib (RMC-6236) With Other Anti-Cancer Agents in Patients With RAS G12C-Mutated NSCLC - Subprotocol A
Where
A Coruña, Badalona, Barcelona, Madrid, Málaga, Pamplona, Sevilla, Valencia
Age
18 years and over
People
330 worldwide
Run by
Revolution Medicines Inc.
See details and how to join2023-509571-16-00 · EU 2023-509571-16-00