Lupus (SLE): open trials in Germany

13 open trials have a site in Germany. Registry data; only the trial team decides who can take part.

NCT07175285
A Study in Participants With Active Systemic Lupus Erythematosus With Inadequate Response to Glucocorticoids and ≥2 Immunosuppressants
Research · Bristol-Myers Squibb
Local Institution - 0041, Kiel · Local Institution - 0043, Mainz
Registry updated 2026-11-02
NCT07201558
Study Evaluating Safety, Tolerability, PK/PD of Surovatamig in Adult RA or SLE Participants
Trial Treatment · Phase 1 · AstraZeneca
Universitaetsklinikum Bonn AöR, Bonn · Universitaetsklinikum Jena KöR, Jena · Universitaetsmedizin der Johannes Gutenberg-Universitaet Mainz KöR, Mainz · Universitatsklinikum Munster AöR, Muenster · LMU Klinikum Muenchen AöR, Munich
Registry updated 2026-10-28
NCT06975787
Dose Escalation Study With Bispecific Antibodies in Adult Participants With Lupus Nephritis
Trial Treatment · Phase 1 · Regeneron Pharmaceuticals
Universitaetsmedizin der Johannes Gutenberg-Universitaet Mainz KöR, Mainz · Universitaetsklinikum Regensburg AöR, Regensburg
Registry updated 2026-10-27
NCT06613360
A Study of CLN-978, a Subcutaneously Administered CD19-directed T Cell Engager, in Subjects With Systemic Lupus Erythematosus
Trial Treatment · Phase 1 · Cullinan Therapeutics Inc.
Universitaetsklinikum Heidelberg AöR, Heidelberg
Registry updated 2026-10-26
NCT06925542
A Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory Autoimmune Disease
Trial Treatment · Phase 1 · CRISPR Therapeutics
University of Augsburg, Augsburg · Universitätsklinikum Köln, Cologne · Medizinische Hochschule Hannover (MHH), Hanover · UCT University Medical Center Mainz, Mainz
Registry updated 2026-10-26
NCT07873931
A Study of BMS-986553 in Participants With Refractory Autoimmune Diseases
Trial Treatment · Phase 1 · Bristol-Myers Squibb
Local Institution - 0028, Berlin · Local Institution - 0060, Erlangen · Local Institution - 0059, Magdeburg · Local Institution - 0027, Würzburg
Registry updated 2026-10-14
NCT07629583
To Evaluate the Effects of Cevostamab in Participants With Systemic Lupus Erythematosus With or Without Active Lupus Nephritis
Trial Treatment · Phase 1 · Genentech, Inc.
Universitaetsmedizin der Johannes Gutenberg-Universitaet Mainz KöR, Mainz · LMU Klinikum Muenchen AöR, Munich
Registry updated 2026-10-06
2022-500699-76-00
Efficacy and Safety of Deucravacitinib Compared with Placebo in Participants with Active SLE (POETYK SLE-1)
Trial Treatment · Phase 3 · Bristol-Myers Squibb Services Unlimited Company
Deutsches Rotes Kreuz Gemeinnuetzige Krankenhaus Sachsen GmbH, Chemnitz · University Hospital Cologne AöR, Cologne · Technische Universität Dresden, Dresden · Universitaetsklinikum Erlangen AöR, Erlangen · Universitaetsklinikum Schleswig-Holstein, Lübeck · Klinikum der Universitaet Muenchen AöR, Munich · Klinische Forschung Im Medizinischen Versorgungsalltag GbR, Planegg · Universitaetsklinikum Tuebingen, Tuebingen
Registry updated 2026-09-21
2023-507654-33-00
MB-CART19.1 in refractory SLE
Trial Treatment · Phase 1/2 · Miltenyi Biomedicine GmbH
Universitaetsklinikum Erlangen AöR, Erlangen · Otto Von Guericke Universitaet Magdeburg, Magdeburg · Universitaetsklinikum Tuebingen AöR, Tuebingen · Universitaetsklinikum Wuerzburg AöR, Wuerzburg
Registry updated 2026-09-15
NCT07201129
A Research Trial to Assess if Cenerimod is Efficacious and Safe to Treat Active Lupus Nephritis on Top of Regular Treatment
Trial Treatment · Phase 3 · Viatris Innovation GmbH
Universitaetsklinikum Koeln AöR, Cologne · Staedtisches Klinikum Dresden, Dresden · Universitaetsklinikum Heidelberg AöR, Heidelberg · LMU Klinikum Muenchen AöR, Munich
Registry updated 2026-07-30
NCT07115745
A Study of Healthy Donor CD19-targeted Allogeneic CAR T Cells in Participants With Severe, Refractory Autoimmune Diseases
Trial Treatment · Phase 1 · Juno Therapeutics, Inc., a Bristol-Myers Squibb Company
Charite Universitaetsmedizin Berlin KöR, Berlin · Technische Universitaet Dresden, Dresden · Universitaetsklinikum Duesseldorf AöR, Duesseldorf · University Medical Center Hamburg-Eppendorf, Hamburg · Universitaetsklinikum Schleswig-Holstein AöR, Kiel
Registry updated 2026-07-14
NCT07403188
A Long-Term Follow-Up Study for Participants Previously Treated With KYV-101
Research · Phase 2/3 · Kyverna Therapeutics
Charite Universitaetsmedizin Berlin KöR, Berlin · Katholisches Klinikum Bochum gGmbH, Bochum · Leibniz Institute Of Virology, Hamburg · Medizinische Hochschule Hannover, Hanover
Registry updated 2026-02-11
NCT06189157
MB-CART19.1 in Refractory SLE
Trial Treatment · Phase 1/2 · Miltenyi Biomedicine GmbH
Universitatsklinikum Erlangen Medizinische Klinik 3, Erlangen · Otto-von-Guericke-Universität Magdeburg, Magdeburg · Universitatsklinikum Tubingen - Medizinische Universitätsklinik Abt. II, Tübingen
Registry updated 2025-11-26

All Lupus (SLE) trials and the map

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