Lupus (SLE) trials in Spain

In Spain 43 Also abroad 354

43 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 10 November 2026. Ask the study team whether a trial fits you.

Phase 1/2Taking people
Study to Evaluate the Safety and Preliminary Efficacy of CD19 CAR-T Cell Therapy (TranspoCART19) in Patients With Refractory Lupus Nephritis
Where
Badalona, León, Madrid, Murcia, Pamplona, Salamanca, Santiago de Compostela, Sevilla
Age
18 years to 65 years
People
10
Run by
Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
See details and how to joinNCT07799116 · EU 2025-522449-23-00
Phase 3Taking people
A Study to Evaluate the Treatment Outcomes of Subcutaneous Anifrolumab in Immunosuppressant-naïve and Biologic-naïve Systemic Lupus Erythematosus
Where
Barcelona, Córdoba, Galdakao, Madrid, Sabadell, San Sebastián de los Reyes, Santander, Sevilla, Valencia
Age
18 years and over
People
113 worldwide
Run by
AstraZeneca AB
See details and how to join2025-523670-17-00 · EU 2025-523670-17-00
Phase 3Taking people
An Efficacy and Safety Study of Intravenous Anifrolumab to Treat Systemic Lupus Erythematosus in Pediatric Participants
Where
Esplugues De Llobregat, Madrid, Málaga, Santiago de Compostela, Valencia
Age
5 years to 17 years
People
100 worldwide
Run by
AstraZeneca
See details and how to joinNCT05835310 · EU 2022-502289-25-00
Phase 3Taking people
A Study to Evaluate the Treatment Outcomes of Subcutaneous Anifrolumab in Immunosuppressant-naïve and Biologic-naïve Systemic Lupus Erythematosus
Where
Barcelona, Córdoba, Galdakao, Madrid, Sabadell, Santander, Seville, Valencia
Age
18 years to 70 years
People
245 worldwide
Run by
AstraZeneca
See details and how to joinNCT07430306
No phaseTaking people
Anifrolumab Malignancy and Serious Infections Study
Where
Barcelona
Age
18 years to 130 years
People
3,506 worldwide
Run by
AstraZeneca
See details and how to joinNCT07000110
Phase 3Enrolling by invitation
Long-term Safety and Tolerability of Cenerimod in Adults With Systemic Lupus Erythematosus
Where
Alcobendas, Madrid, Sabadell, Santiago de Compostela, Valladolid
Age
18 years to 75 years
People
680 worldwide
Run by
Viatris Innovation GmbH
See details and how to joinNCT06475742 · EU 2024-514354-67-00
Phase 2Taking people
Treatment of Lupus Nephritis With Allogeneic Mesenchymal Stem Cells
Where
Valladolid
Age
18 years to 64 years
People
20
Run by
Red de Terapia Celular
See details and how to joinNCT03673748 · EU 2024-514750-67-00
Phase 1Taking people
A Phase 1 Study of the Safety and Preliminary Efficacy of CTX112 in Adult Subjects With Refractory Autoimmune Disease.
Where
Córdoba, Pamplona, Sevilla, Valencia
Age
18 years and over
People
51 worldwide
Run by
CRISPR Therapeutics AG
See details and how to join2024-518528-54-00 · EU 2024-518528-54-00
Phase 3Taking people
A Research Trial to Assess if Cenerimod is Efficacious and Safe to Treat Active Lupus Nephritis on Top of Regular Treatment
Where
Alcobendas, Barcelona, Bilbao, Girona, Madrid, Pamplona, Valencia
Age
18 years to 75 years
People
300 worldwide
Run by
Viatris Innovation GmbH
See details and how to joinNCT07201129 · EU 2025-522984-14-00
Phase 1Taking people
A Study of Healthy Donor CD19-targeted Allogeneic CAR T Cells in Participants With Severe, Refractory Autoimmune Diseases
Where
Barcelona, Madrid
Age
18 years and over
People
125 worldwide
Run by
Juno Therapeutics, Inc., a Bristol-Myers Squibb Company
See details and how to joinNCT07115745 · EU 2024-517681-41-00
Phase 1Taking people
A study to find how well budoprutug (TNT119) works and how safe it is in participants with Systemic Lupus Erythematosus
Where
A Coruña, Sabadell
Age
18 years and over
People
11 worldwide
Run by
Climb Bio Inc.
See details and how to join2024-520385-57-01 · EU 2024-520385-57-01
Phase 1Taking people
A Study of GSK5926371 in Participants With B-cell Driven Autoimmune Rheumatic Diseases (ARD)
Where
Barcelona, Madrid, Majadahonda
Age
18 years to 70 years
People
44 worldwide
Run by
GlaxoSmithKline
See details and how to joinNCT07371468 · EU 2025-522932-15-00
Phase 1Taking people
A Study of GSK4527363 in Healthy Participants, Systemic Lupus Erythematosus (SLE) Participants, Healthy Chinese, and Japanese Participants and CTD-ILD Participants
Where
Badalona, Bilbao, Pamplona, Sabadell, Valladolid
Age
18 years to 65 years
People
142 worldwide
Run by
GlaxoSmithKline
See details and how to joinNCT06576271 · EU 2024-514186-18-00
Phase 4Taking people
Carotid Ultrasound-Based Strategy for Primary Prevention of Cardiovascular Events in Inflammatory Rheumatic Disease (PREVENER)
Where
Barcelona, Bilbao, Ciudad Real, Córdoba, Elche, Las Palmas De Gran Canaria, Madrid, Murcia, Orihuela, Palma, San Cristóbal de La Laguna, Santander, Sant Joan d'Alacant, Torrelavega, Vitoria, Hospital laredo
Age
50 years and over
People
1,944
Run by
Instituto de Investigación Marqués de Valdecilla
See details and how to joinNCT07611747 · EU 2025-521086-28-00
No phaseNot yet taking people in Spain
Identification of Modifiable Sleep-related Factors in Patients With Systemic Lupus Erythematosus.
Where
Oviedo
Age
18 years and over
People
250
Run by
Investigación en Hemofilia y Fisioterapia
See details and how to joinNCT07483541
Phase 1Taking people
A Phase 1b Study of Budoprutug in Systemic Lupus Erythematosus (SLE)
Where
A Coruña, Sabadell
Age
18 years to 65 years
People
30 worldwide
Run by
Climb Bio, Inc.
See details and how to joinNCT07011043
No phaseNot yet taking people in Spain
Physical Activity in Patients With Systemic Lupus Erythematosus
Where
Oviedo
Age
18 years to 65 years
People
63
Run by
University of Oviedo
See details and how to joinNCT06919250
No phaseNot yet taking people in Spain
Belimumab in Patients With Systemic Lupus Erythematosus
Where
Barcelona
Age
18 years and over
People
3,000
Run by
Grupo de Trabajo de Enfermedades Autoinmunes Sistémicas (GEAS) de la Fundación Española de Medicina
See details and how to joinNCT04671706