Macular degeneration: open trials in Italy

27 open trials have a site in Italy. Registry data; only the trial team decides who can take part.

NCT06541704
A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy
Trial Treatment · Phase 3 · Regeneron Pharmaceuticals
Azienda Ospedaliero-Universitaria delle Marche, Ancona · Azienda Ospedaliero - Universitaria di Cagliari, Cagliari · Careggi University Hospital, Florence · Ospedale San Raffaele S.r.l., Milan · Multimedica S.p.A., Milan · Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan · ASST Fatebenefratelli Sacco, Milan · Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome · Fondazione G.B.Bietti Per Lo Studio E La Ricerca In Oftalmologia, Rome · Azienda Ospedaliera Policlinico Universitario Tor Vergata, Rome
Registry updated 2026-11-05
NCT06635148
A Long-term Extension Study of JNJ-81201887 (AAVCAGsCD59) Parent Studies in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)
Trial Treatment · Phase 2/3 · Janssen Research & Development, LLC
University Hospital Of Ferrara, Ferrara · Ospedale San Raffaele S.r.l., Milan · Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan · ASST Fatebenefratelli Sacco, Milan · Azienda Ospedaliera Universitaria - Universita degli Studi della Campania Luigi Vanvitelli, Naples · Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome
Registry updated 2026-11-03
NCT07007065
Study to Assess the Injection Burden, Adverse Events, Change in Disease Activity, and Long-Term Preservation of Visual Acuity of Surabgene Lomparvovec in Adult Participants With Neovascular Age-Related Macular Degeneration (nAMD)
Trial Treatment · Phase 3 · AbbVie
Azienda Ospedaliero-Universitaria delle Marche, Ancona · University Hospital Of Ferrara, Ferrara · Azienda Ospedaliero-Universitaria Careggi, Florence · Azienda USL IRCCS di Reggio Emilia, Reggio Emilia · Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome · Azienda Ospedaliera Universitaria Citta Della Salute E Della Scienza Di Torino, Turin
Registry updated 2026-10-29
NCT03683251
Extension Study for the Port Delivery System With Ranibizumab (Portal)
Trial Treatment · Phase 3 · Hoffmann-La Roche
Azienda Ospedaliero-Universitaria delle Marche, Ancona · Azienda Ospedaliero Universitaria Consorziale Policlinico, Bari · Azienda Sanitaria Locale 2 Lanciano Vasto Chieti, Chieti · Careggi University Hospital, Florence · ASST Fatebenefratelli Sacco, Milan · Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan · Ospedale San Raffaele S.r.l., Milan · IRCCS Ospedale Sacro Cuore Don Calabria, Negrar · Hospital Santa Maria Della Misericordia, Perugia · Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome · Fondazione G.B.Bietti Per Lo Studio E La Ricerca In Oftalmologia, Rome · Azienda Sanitaria Universitaria Giuliano Isontina, Trieste · Azienda Sanitaria Universitaria Friuli Centrale, Udine
Registry updated 2026-10-27
NCT06659549
A Phase 2 Efficacy and Safety Study of GAL-101, 2% Ophthalmic Solution in Non-foveal Geographic Atrophy Secondary to Non-neovascular AMD
Trial Treatment · Phase 2 · Galimedix Therapeutics Inc
Multimedica S.p.A., Milan · Ospedale San Raffaele S.r.l., Milan · Fondazione G.B.Bietti Per Lo Studio E La Ricerca In Oftalmologia, Rome
Registry updated 2026-10-22
NCT07064759
Single Intravitreal (IVT) Injection of 4D-150 in Patients With Macular Neovascularization Secondary to Age-Related Macular Degeneration
Trial Treatment · Phase 3 · 4D Molecular Therapeutics
AOU delle Marche, Ancona
Registry updated 2026-10-19
NCT06847542
A Study of 36-Week Refill Exchanges of Port Delivery System (PDS) With Ranibizumab in nAMD
Trial Treatment · Phase 3 · Hoffmann-La Roche
University Hospital Of Ferrara, Ferrara · Azienda Socio Sanitaria Territoriale Santi Paolo E Carlo, Milan · Azienda Ospedaliera dei Colli, Naples · Azienda Ospedaliero Universitaria Maggiore della Carità, Novara · Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone, Palermo · Ospedale Isola Tiberina - Gemelli Isola, Rome · Azienda Ospedaliera Universitaria Citta Della Salute E Della Scienza Di Torino, Turin
Registry updated 2026-10-15
NCT07441642
A Study to Investigate Efficacy and Safety of FWY003 Compared With Placebo in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration
Trial Treatment · Phase 2 · Novartis Pharmaceuticals
Florence · Milan · Roma
Registry updated 2026-10-13
2025-524894-17-00
A clinical trial of EYE201/MK-8748 in people with macular degeneration (MK-8748-003)
Trial Treatment · Phase 2/3 · Eyebiotech Limited
University Hospital Of Ferrara, Ferrara · Azienda Ospedaliero-Universitaria Careggi, Florence · Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan · Ospedale San Raffaele S.r.l., Milan · ASST Fatebenefratelli Sacco, Milan · Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome · Azienda Ospedaliera Policlinico Universitario Tor Vergata, Rome · Fondazione G.B.Bietti Per Lo Studio E La Ricerca In Oftalmologia, Rome · Azienda Ospedaliera Universitaria Citta Della Salute E Della Scienza Di Torino, Turin · Azienda Sanitaria Universitaria Friuli Centrale, Udine
Registry updated 2026-09-10
NCT06659445
Study to Evaluate Efficacy and Safety of ONL1204 in Patients With GA Associated With AMD
Trial Treatment · Phase 2 · ONL Therapeutics
Azienda Ospedaliero-Universitaria delle Marche, Ancona · Azienda Ospedaliero-Universitaria Di Bologna IRCCS Istituto Di Ricerca E Di Cura A Carattere Scientifico, Bologna · ASST Fatebenefratelli Sacco, Milan · IRCCS Ospedale Sacro Cuore Don Calabria, Negrar · Azienda Ospedaliera Policlinico Universitario Tor Vergata, Rome · Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome · Azienda Ospedaliera Universitaria Citta Della Salute E Della Scienza Di Torino, Turin
Registry updated 2026-09-10
NCT07554690
Photobiomodulation Laser for Reticular Pseudodrusen in Age-Related Macular Degeneration
Trial Treatment · Fondazione G.B. Bietti, IRCCS
IRCCS Fondazione G.B.Bietti c/o Ospedale Britannico, Roma
Registry updated 2026-09-04
NCT06990269
Phase 2 Study of ADX-038 in Participants With Geographic Atrophy
Trial Treatment · Phase 2 · ADARx Pharmaceuticals, Inc.
Ospedale San Raffaele S.r.l., Milan · ASST Fatebenefratelli Sacco, Milan · Azienda Socio Sanitaria Territoriale Santi Paolo E Carlo, Milan · Azienda Ospedaliero Universitaria Maggiore della Carità, Novara · Azienda Ospedaliera di Padova, Padova · Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome
Registry updated 2026-09-03
NCT07338461
High Resolution Imaging OCT Study
Trial Treatment · Heidelberg Engineering GmbH
Department of Biomedical and Clinical Sciences, Luigi Sacco Hospital, University of Milan, Milan
Registry updated 2026-08-26
NCT07496567
A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-003)
Trial Treatment · Phase 2/3 · EyeBiotech Ltd.
Presidio Ospedaliero Universitario "Santa Maria della Misericordia" Clinica Oculistica - Padiglione 7 - Piano 3, Udine
Registry updated 2026-08-06
2025-523704-77-00
A clinical trial to learn more about the effects of FWY003 in people with geographic atrophy associated with age-related macular degeneration.
Trial Treatment · Phase 2 · Novartis Pharma AG
Azienda Ospedaliero-Universitaria Careggi, Florence · Ospedale San Raffaele S.r.l., Milan · Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan · Fondazione G.B.Bietti Per Lo Studio E La Ricerca In Oftalmologia, Rome
Registry updated 2026-06-23
NCT07500324
Proteomic Biomarker Identification in Age-Related Macular Degeneration, Diabetic Retinopathy and Retinal Detachment
Trial Treatment · Fondazione G.B. Bietti, IRCCS
IRCCS Fondazione G.B. Bietti, Roma
Registry updated 2026-06-02
NCT06906003
Visual Rehabilitation and Depression in Visually Impaired Patients With AMD
Research · Fondazione G.B. Bietti, IRCCS
Irccs Fondazione G. B. Bietti, Rome
Registry updated 2026-06-01
NCT07164378
International Study of the SING IMT™ Prosthesis in Pseudophakic patiEnts With Stable Moderate to Profound Bilateral Central vIsion Impairment Due to adVancEd AMD / PERSPECTIVE Study
Trial Treatment · VisionCare, Inc.
Ospedale Generale Regionale "F. Miulli", Bari · IRCCS Humanitas, Bergamo · Azienda Ospedaliero Universitaria di Ferrara, Ferrara · Presidio Ospedaliero Palagi, Florence · Policlinico Universitario Fondazione Agostino Gemelli, Roma
Registry updated 2026-03-20
NCT07427160
Prognostic Role of Macular Neovascular Membrane Subtype in Pneumatic Displacement of Macular Hemorrhages
Research · Marco Mazzola
Ospedale Santa Chiara di Trento, Trento
Registry updated 2026-02-23
NCT07305298
Mirabegron in Patients With Age-Related Macular Degeneration
Research · University of Naples
Federico II, Naples
Registry updated 2026-02-06
NCT05706896
Atrophic Age-related Macular Degeneration Treated With Intravitreal Injections of Umbilical Cord Blood Platelet-rich Plasma
Trial Treatment · Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome
Registry updated 2025-09-23
NCT06536062
Age-related Macular Degeneration of Atrophic Type Treated With Umbilical Cord Blood Enriched With Platelet Plasma.
Trial Treatment · Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome
Registry updated 2025-09-23
NCT06925893
Lutein by Scleral Iontophoresis in AMD
Research · Federico II University
Federico II University, Naples
Registry updated 2025-04-13
NCT06899360
Evaluation of Clinical Progression, Prognostic Factors, and Quality of Life in Patients with Age-related Macular Degeneration.
Research · University of Udine
Department of Ophthalmology, Udine
Registry updated 2025-03-27
NCT04847635
Subthreshold Laser Treatment for Reticular Pseudodrusen Secondary to Age-related Macular Degeneration
Trial Treatment · Ospedale San Raffaele
Massimo Nicolò, Genova · Giuseppe Querques, Milan · Mariacristina Parravano, Rome
Registry updated 2025-03-12

All Macular degeneration trials and the map

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