Macular degeneration: open trials in Latvia

• NCT07064759

  Single Intravitreal (IVT) Injection of 4D-150 in Patients With Macular Neovascularization Secondary to Age-Related Macular Degeneration

  Trial Treatment · Phase 3 · 4D Molecular Therapeutics

  Riga East University Hospital, Riga · P.Stradins University Hospital, Riga · Ziemekurzemes Regionala Slimnica, Ventspils

  Registry updated 2026-10-19

• NCT07614776

  A Study to Evaluate Efficacy, Safety, and Immunogenicity With ABP 938 8 mg Versus EYLEA® HD (Aflibercept) in Participants With Neovascular Age-related Macular Degeneration

  Trial Treatment · Phase 3 · Amgen

  Riga East University Hospital - Department of Ophthalmology, Clinical Center "Bikernieki", Riga · Pauls Stradins Clinical University Hospital, Riga · Latvijas Amerikas Acu Centrs SIA, Riga · Ziemelkurzemes regionala slimnica SIA, Ventspils

  Registry updated 2026-10-14

• NCT07440225

  A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002)

  Trial Treatment · Phase 2/3 · EyeBiotech Ltd.

  P. Stradins Clinical University Hospital, Riga · Riga East University hospital, clinical centre Bikernieki, Riga · Northern Kurzeme Regional Hospital, Ventspils

  Registry updated 2026-10-02

• 2026-526648-11-00

  A Phase II/III Multicenter, Randomized, Masked, Active Comparator-Controlled Study to Evaluate the Safety and Efficacy of Two Doses of OCUL101, an Anti-VEGF and Anti-Complement C5, Bi-specific Humanized Antibody-Like “trap” in Participants with Neovascular Age-Related Macular Degeneration with or without Geographic Atrophy – STAT Study

  Trial Treatment · Phase 2/3 · Shenzhen Oculgen Biomedical Technology Co. Ltd.

  Latvijas Amerikas Acu Centrs SIA, Riga · Pauls Stradins Clinical University Hospital, Riga · Rigas Austrumu kliniska universitates slimnica SIA, Riga · Ziemelkurzemes regionala slimnica SIA, Ventspils

  Registry updated 2026-09-25

• 2025-524575-22-00

  A randomized double-masked, multicenter, 3 arm pivotal Phase 2/3 study to evaluate the efficacy and safety of intravitreal (IVT) EYE201/MK-8748 in participants with neovascular age-related macular degeneration (NVAMD)

  Trial Treatment · Phase 2/3 · Eyebiotech Limited

  Riga East University Hospital - Department of Ophthalmology, Clinical Center "Bikernieki", Riga · Pauls Stradins Clinical University Hospital, Riga · Northern Kurzeme Regional Hospital, Ventspils

  Registry updated 2026-06-12

All Macular degeneration trials and the map

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