Melanoma trials in Australia

In Australia 48 Also abroad 578

48 trials · From ClinicalTrials.gov, checked 11 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
The Multicentre Selective Lymphadenectomy Trial - 3
Where
Murdoch, Newcastle, Wollstonecraft
Age
18 years and over
People
1,500 worldwide
Run by
Melanoma Institute Australia
See details and how to joinNCT07049276
Phase 2Not yet taking people in Australia
A Phase II Trial of Tumour Infiltrating Lymphocyte Adoptive Cell Therapy in Patients With Immune Checkpoint Inhibitor Resistant Unresectable or Metastatic Melanoma
Where
Perth
Age
18 years to 70 years
People
10
Run by
East Metropolitan Health Service, Australia
See details and how to joinNCT07651618
Phase 1/2Taking people
A Study to Investigate the Safety and Efficacy of IOV-3001 in Adults With Advanced Melanoma Who Will Receive Lifileucel
Where
Greenslopes, Nedlands
Age
18 years to 70 years
People
42 worldwide
Run by
Iovance Biotherapeutics, Inc.
See details and how to joinNCT06940739
Phase 3Taking people
Duration of Anti-PD-1 Therapy in Metastatic Melanoma
Where
Birtinya, Cairns, Clayton, Coffs Harbour, Herston, Melbourne, Southport, Victoria, Waratah, Westmead, Woodville
Age
18 years and over
People
614 worldwide
Run by
Canadian Cancer Trials Group
See details and how to joinNCT02821013
Phase 1/2Taking people
Study of IDE196 in Patients With Solid Tumors Harboring GNAQ/11 Mutations or PRKC Fusions
Where
Sydney, Woolloongabba
Age
18 years and over
People
336 worldwide
Run by
IDEAYA Biosciences
See details and how to joinNCT03947385
Phase 2Taking people
Stereotactic Ablative Radiotherapy (XRT) and Immunotherapy for Oligometastatic Extracranial Melanoma
Where
Melbourne, Westmead, Wollstonecraft, Woolloongabba
Age
18 years and over
People
129 worldwide
Run by
Melanoma Institute Australia
See details and how to joinNCT06767306
Phase 3Taking people
Neoadjuvant Darovasertib in Primary Uveal Melanoma
Where
Greenslopes, Melbourne, Westmead, Woodville South
Age
18 years and over
People
520 worldwide
Run by
IDEAYA Biosciences
See details and how to joinNCT07015190 · EU 2025-522387-32-00
Phase 1Taking people
Tebentafusp and Roginolisib in Uveal Melanoma to Prolong T-cell Homeostasis
Where
Melbourne, Sydney
Age
18 years and over
People
8
Run by
St Vincent's Hospital, Sydney
See details and how to joinNCT07203391
Phase 1Taking people
A Study to Investigate the Safety and Efficacy of NST-628 Oral Tablets in Subjects With Solid Tumors
Where
Adelaide, Darlinghurst, Greenslopes, Malvern, Randwick
Age
18 years and over
People
230 worldwide
Run by
Nested Therapeutics, Inc
See details and how to joinNCT06326411
Phase 2/3Taking people
A Randomized, Phase 2/3 Study to Investigate the Efficacy and Safety of RP2 in Combination With Nivolumab in Immune Checkpoint Inhibitor-Naïve Adult Patients With Metastatic Uveal Melanoma
Where
Melbourne, Wollstonecraft
Age
18 years and over
People
280 worldwide
Run by
Replimune, Inc.
See details and how to joinNCT06581406 · EU 2023-508784-68-00
Phase 1/2Taking people
A Phase 1/2 Clinical Trial to Assess the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of HMBD-501 in Patients With HER3-Expressing Solid Tumors
Where
Campbelltown, Miranda
Age
18 years and over
People
180 worldwide
Run by
Hummingbird Bioscience
See details and how to joinNCT06956690
Phase 3Taking people
Tebentafusp Regimen Versus Investigator's Choice in Previously Treated Advanced Melanoma (TEBE-AM)
Where
Greenslopes, Melbourne, Wollstonecraft, Woolloongabba
Age
18 years and over
People
540 worldwide
Run by
Immunocore Ltd
See details and how to joinNCT05549297 · EU 2022-502732-39-00
Phase 3Taking people
IMC-F106C Regimen Versus Nivolumab Regimens in Previously Untreated Advanced Melanoma (PRISM-MEL-301)
Where
Greenslopes, Heidelberg, Nedlands, North Melbourne, Waratah, Wollstonecraft, Woolloongabba
Age
18 years and over
People
680 worldwide
Run by
Immunocore Ltd
See details and how to joinNCT06112314
Phase 2Taking people
Neo IRENIE (NEOadjuvant Ipilimumab, RElatlimab, NIvolumab Evaluation)
Where
Wollstonecraft
Age
18 years and over
People
494
Run by
Melanoma Institute Australia
See details and how to joinNCT06999980
No phaseTaking people
IMmune checkPoint Inhibitor Related gonAdal toxiCiTy in Premenopausal Women and Men With Melanoma
Where
Brisbane, Cairns, Melbourne, Sydney
Age
18 years to 60 years
People
80
Run by
Peter MacCallum Cancer Centre, Australia
See details and how to joinNCT07138222
Phase 4Taking people
A Study to Assess the Long-term Safety Outcomes in Patients Previously Treated With RP1, RP2, or RP3
Where
Southport
Age
18 years and over
People
50 worldwide
Run by
Replimune, Inc.
See details and how to joinNCT06887348 · EU 2025-521621-33-00
Phase 1Taking people
A Dose Escalation and Dose Expansion Study of Intratumoral ONM-501 Alone and in Combination With Cemiplimab in Patients With Advanced Solid Tumors and Lymphomas.
Where
Bedford Park, Buderim, Darlinghurst, Southport, Subiaco, Wollongong, Woolloongabba
Age
18 years and over
People
168 worldwide
Run by
OncoNano Medicine, Inc.
See details and how to joinNCT06022029
Phase 1/2Taking people
Phase 1/2 Study of Intratumoral Injection of STX-001 in Advanced Solid Tumors as Monotherapy or in Combination With Pembrolizumab
Where
Wollstonecraft
Age
18 years and over
People
108 worldwide
Run by
Strand Therapeutics Inc.
See details and how to joinNCT06249048
Phase 1/2Taking people
A Clinical Study of Intratumoral MVR-T3011 (T3011) Given as a Single Agent and in Combination With Intravenous Pembrolizumab in Participants With Advanced or Metastatic Solid Tumors
Where
Bedford Park, Frankston, Melbourne
Age
18 years and over
People
30 worldwide
Run by
ImmVira Pharma Co. Ltd
See details and how to joinNCT04370587
Phase 1/2Taking people
Adding IL-2 to Tebentafusp to Eradicate Cancer Progression
Where
Melbourne, Sydney
Age
18 years and over
People
8
Run by
St Vincent's Hospital, Sydney
See details and how to joinNCT07063875
No phaseTaking people
Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma
Where
Adelaide, Brisbane, Bruce, Garran, Gold Coast, Melbourne, Sydney
Age
18 years and over
People
2,998 worldwide
Run by
Melanoma and Skin Cancer Trials Limited
See details and how to joinNCT03860883
Phase 2Taking people
Phase II Trial of Neoadjuvant and Adjuvant IO102-IO103 and Pembrolizumab KEYTRUDA® in Patients With Resectable Tumors
Where
Melbourne, Sydney
Age
18 years and over
People
60 worldwide
Run by
IO Biotech
See details and how to joinNCT05280314
No phaseTaking people
Metabolic Phenotypes in Melanoma
Where
Melbourne
Age
18 years and over
People
240
Run by
Peter MacCallum Cancer Centre, Australia
See details and how to joinNCT05570227