Melanoma: open trials in Germany

49 open trials have a site in Germany. Registry data; only the trial team decides who can take part.

NCT07492680
A Study of Navlimetostat (BMS-986504) Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5)
Trial Treatment · Phase 2 · Bristol-Myers Squibb
Universitaetsklinikum Hamburg, Hamburg · Heidelberg · Universitaetsklinikum Leipzig, Leipzig · Universitaetsmedizin der Johannes Gutenberg - Universitaet Mainz, Mainz · Klinikum Rechts der Isar der Technischen Universitaet Muenchen, München · Universitaetsklinikum Wuerzburg, Würzburg
Registry updated 2026-11-04
NCT03340506
Dabrafenib and/or Trametinib Rollover Study
Trial Treatment · Phase 4 · Novartis Pharmaceuticals
Universitaetsklinikum Augsburg, Augsburg · Universitaetsklinikum Essen (AoR), Essen · University Medical Center Hamburg-Eppendorf, Hamburg · Universitaetsklinikum Heidelberg AöR, Heidelberg · Universitaetsklinikum Mannheim GmbH, Mannheim
Registry updated 2026-11-03
NCT07913412
High-precision Radiosurgery Followed by Minimally Invasive Surgical Approach in Patients With High-prominence Uveal Melanoma: Modern Radiation Techniques and Outcomes
Research · University Hospital, Essen
University Hospital Essen, Essen · Department for Radiotherapy, University Hospital Essen, National Center for Tumor Diseases (NCT) West, Essen · Maja Guberina, Essen
Registry updated 2026-11-03
NCT06743126
SUPRAME-ACTengine® IMA203 vs. Investigator's Choice of Treatment in Previously Treated, Unresectable or Metastatic Cutaneous Melanoma
Trial Treatment · Phase 3 · Immatics US, Inc.
Charite Universitaetsmedizin Berlin KöR, Berlin · Universitaetsklinikum Bonn AöR, Bonn · University Hospital Cologne AöR, Cologne · Technische Universitaet Dresden, Dresden · Universitaetsklinikum Erlangen AöR, Erlangen · Universitaetsklinikum Essen (AoR), Essen · Goethe University Frankfurt, Frankfurt Am Main · University Medical Center Hamburg-Eppendorf, Hamburg · Universitaetsklinikum Heidelberg AöR, Heidelberg · Universitaet Leipzig, Leipzig · Universitaetsmedizin der Johannes Gutenberg-Universitaet Mainz KöR, Mainz
Registry updated 2026-10-30
NCT06953089
DB-1311 in Combination With BNT327 or DB-1305 in Advanced/Metastatic Solid Tumors
Trial Treatment · Phase 2 · DualityBio Inc.
Krankenhaus Nordwest GmbH, Frankfurt am Main · Justus-Liebig-Universitaet Giessen, Giessen
Registry updated 2026-10-29
NCT06172478
A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
Trial Treatment · Phase 2 · Daiichi Sankyo
Krankenhaus Nordwest GmbH, Frankfurt
Registry updated 2026-10-26
NCT06330064
A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02)
Trial Treatment · Phase 1/2 · Daiichi Sankyo
Charite Universitaetsmedizin Berlin KöR, Berlin · Vivantes Netzwerk fuer Gesundheit GmbH, Berlin · Staedtisches Klinikum Dresden, Dresden · Universitaetsklinikum Heidelberg AöR, Heidelberg · SLK-Kliniken Heilbronn GmbH, Heilbronn · Universitaet Leipzig, Leipzig · Universitaetsmedizin der Johannes Gutenberg-Universitaet Mainz KöR, Mainz · Universitaet Muenster, Muenster
Registry updated 2026-10-26
NCT07883954
Development and Multi-Centre Validation of a Novel Non-Invasive Melanoma Molecular Diagnostic Test
Research · Mitra Bio
University Hospital Tuebingen, Tübingen
Registry updated 2026-10-21
NCT06508775
Long-Term Follow-up of Patients Treated With Miltenyi Cell and Gene Therapies
Trial Treatment · Phase 1/2 · Miltenyi Biomedicine GmbH
Charite Universitaetsmedizin Berlin KöR, Berlin · University Hospital Cologne AöR, Cologne · Universitaetsklinikum Erlangen AöR, Erlangen · Universitaetsmedizin Goettingen, Goettingen · Westfaelische Wilhelms-Universitaet Muenster, Muenster · Universitaetsklinikum Muenster AöR, Muenster · Klinikum der Universitaet Muenchen AöR, Munich · Universitaetsklinikum Tuebingen AöR, Tuebingen · Universitaetsklinikum Wuerzburg AöR, Wuerzburg
Registry updated 2026-10-09
NCT07070232
A Clinical Study to Test if an Investigational Treatment Called BNT326 is Safe and Potentially Beneficial When Used Alone or in Combination With Other Investigational Treatments Such as BNT327, for People With Advanced Malignant Tumors
Trial Treatment · Phase 1/2 · BioNTech SE
Charité - Campus Charité Mitte, Berlin · Universitaetsklinikum - Essen, Essen · Universitätsmedizin der Johannes Gutenberg-Universität Mainz, Mainz · Klinikum der Universität München Campus Grosshadern, München · Universitätsklinikum Tübingen, Tübingen
Registry updated 2026-10-09
NCT06697301
Safety and Efficacy of EIK1001 in Combo With Pembro Versus Placebo and Pembro as First-Line Therapy in Patients With Advanced Melanoma.
Trial Treatment · Phase 2/3 · Eikon Therapeutics
Charite Universitaetsmedizin Berlin KöR, Berlin · Elbe Kliniken Stade-Buxtehude Elbe Klinikum Buxtehude gGmbH, Buxtehude · Universitaetsklinikum Carl Gustav Carus Dresden an der Technischen Universitaet Dresden AöR, Dresden · HELIOS Klinikum Erfurt GmbH, Erfurt · Universitaetsklinikum Erlangen AöR, Erlangen · SRH Wald-Klinikum Gera GmbH, Gera · Martin-Luther-Universitaet Halle-Wittenberg, Halle (Saale) · University Medical Center Hamburg-Eppendorf, Hamburg · Universitaetsklinikum Schleswig-Holstein AöR, Kiel · Universitaet Leipzig, Leipzig · Klinikum der Stadt Ludwigshafen am Rhein gGmbH, Ludwigshafen Am Rhein · Universitaetsklinikum Schleswig-Holstein AöR, Luebeck · Otto Von Guericke Universitaet Magdeburg, Magdeburg · Universitaetsmedizin der Johannes Gutenberg-Universitaet Mainz KöR, Mainz · Heidelberg University, Mannheim · Philipps-Universitaet Marburg, Marburg · Muehlenkreiskliniken AöR, Minden · Fachklinik Hornheide e.V., Muenster · Klinikum Nuernberg, Nuremberg · Universitaetsklinikum Tuebingen AöR, Tuebingen · Universitaetsklinikum Wuerzburg AöR, Wuerzburg
Registry updated 2026-10-06
2026-526261-14-00
PHOENIX - ECP: Extracorporeal PHotopheresis for immune-related cOlitis and/or hEpatitis in advanced melaNoma with inadequate response to steroId eXposure
Trial Treatment · Phase 2 · Therakos Europe Limited
Charite Universitaetsmedizin Berlin KöR, Berlin · Universitaetsklinikum Koeln AöR, Cologne · Universitaetsklinikum Carl Gustav Carus Dresden an der Technischen Universitaet Dresden AöR, Dresden · Universitaetsklinikum Essen (AoR), Essen · Medical Center- University of Freiburg, Freiburg im Breisgau · Martin-Luther-Universitaet Halle-Wittenberg, Halle (Saale) · Universitaetsklinikum Schleswig-Holstein AöR, Luebeck · Universitaetsmedizin der Johannes Gutenberg-Universitaet Mainz KöR, Mainz · Universitaetsklinikum Mannheim GmbH, Mannheim · LMU Klinikum Muenchen AöR, Munich
Registry updated 2026-10-05
NCT06961006
A Clinical Study of Intismeran Autogene (V940) and Pembrolizumab (MK-3475) in People With Melanoma (V940-012/INTerpath-012)
Trial Treatment · Phase 2 · Merck Sharp & Dohme LLC
Universitaetsklinikum Koeln ( Site 2064), Cologne · Universitaetsklinikum Essen ( Site 2061), Essen · Universitätsklinikum Frankfurt Goethe-Universität ( Site 2063), Frankfurt am Main · Universitaetsklinikum Hamburg-Eppendorf ( Site 2060), Hamburg · NCT ( Site 2065), Heidelberg
Registry updated 2026-09-28
NCT05727904
Study to Investigate Lifileucel Regimen Plus Pembrolizumab Compared With Pembrolizumab Alone in Participants With Untreated Advanced Melanoma.
Trial Treatment · Phase 3 · Iovance Biotherapeutics, Inc.
Charite Universitaetsmedizin Berlin KöR, Berlin · Technische Universitaet Dresden, Dresden · University Medical Center Hamburg-Eppendorf, Hamburg · Universitaetsklinikum Schleswig-Holstein, Lübeck · Klinikum rechts der Isar der TU Muenchen AöR, Munich · LMU Klinikum Muenchen AöR, Munich · Universitäts-klinikum Würzburg, Würzburg
Registry updated 2026-09-24
2024-512219-37-00
Early detection of side effects in patients with metastatic melanoma receiving immune checkpoint inhibitor therapy by investigation of the CD8+ immune infiltrate using [89Zr]Zr-Df-IAB22M2C-PET
Trial Treatment · Phase 2 · Universitaetsklinikum Tuebingen AöR
Universitaetsklinikum Tuebingen AöR, Tuebingen
Registry updated 2026-09-22
NCT07057596
Neoadjuvant Tebentafusp in Patients With Metastatic Uveal Melanoma
Trial Treatment · Phase 2 · Grupo Español Multidisciplinar de Melanoma
Charite Universitaetsmedizin Berlin KöR, Berlin
Registry updated 2026-09-15
NCT05059444
ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation
Research · Guardant Health, Inc.
Asklepios Klinik Altona, Hamburg · SLK-Kliniken Heilbronn GmbH, Heilbronn · Ludwig Maximilian University Munich, Munich
Registry updated 2026-09-14
NCT06284590
Study of the Efficacy of Intratumoral L19IL2 or L19TNF or L19IL2/L19TNF, in Combination With Pembrolizumab, in Unresectable Melanoma Patients
Trial Treatment · Phase 2 · Philogen S.p.A.
Universitätsklinikum Essen, Essen · Medical Center- University of Freiburg, Freiburg im Breisgau · Universitaetsklinikum Schleswig-Holstein AöR, Kiel · Universitaetsklinikum Tuebingen AöR, Tuebingen
Registry updated 2026-09-02
NCT07788729
Social Prescriptions and Micro-Learning to Improve Care for Cancer Patients and Their Support Persons
Trial Treatment · University of Regensburg
University Hospital Augsburg, Augsburg · Faculty of Law, Business & Economics, Inst. for Healthcare Management & Health Sciences, Bayreuth · Charité - University Medicine Berlin, Berlin · University Hospital Köln, Cologne · University Hospital Erlangen, Erlangen · University Regensburg, Regensburg · University Hospital Regensburg, Regensburg · University Hospital Würzburg, Würzburg
Registry updated 2026-08-26
NCT07649681
Gustabor Phase 2 - Treating Taste Changes During Cancer Therapy: A Randomized Study Evaluating an AI- Based Nutrition Intervention
Trial Treatment · Wuerzburg University Hospital
Universitätsklinikum Augsburg, Augsburg · Universitätsklinikum Erlangen, Erlangen · Klinikum der Technischen Universität München (TUM Klinikum), München · LMU Klinikum Krebszentrum - CCC MünchenLMU - Comprehensive Cancer Center, München · Universitätsklinikum Regensburg, Regensburg · Universitätsklinikum Würzburg, Würzburg
Registry updated 2026-08-20
NCT07338968
A Long-Term Follow-Up Study of Subjects Completing the AU-011-301(CoMpass) for Early Choroidal Melanoma
Research · Phase 3 · Aura Biosciences
Charite Universitaetsmedizin Berlin KöR, Berlin · Universitaetsklinikum Essen (AoR), Essen · University Medical Center Hamburg-Eppendorf, Hamburg · LMU Klinikum Muenchen AöR, Munich
Registry updated 2026-08-19
NCT04895709
A Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors
Trial Treatment · Phase 1/2 · Bristol-Myers Squibb
Universitaetsklinikum Carl Gustav Carus Dresden-University Cancer Center Early Clinical Trial Unit, Dresden · Universitaetsklinikum - Essen, Essen · Universitätsklinikum Frankfurt, Frankfurt · Ulm · Universitaetsklinikum Wuerzburg, Würzburg
Registry updated 2026-08-17
NCT07600476
A First-in-Human Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of KUP-101A in Patients With Selected Advanced Solid Tumors
Trial Treatment · Phase 1 · Kupando GmbH
St. Josef Hospital, Bochum · Universitaetsklinikum Koeln AöR, Cologne · Philipps-Universitaet Marburg, Marburg · Fachklinik Hornheide e.V., Muenster · LMU Klinikum Muenchen AöR, Munich · Universitaetsklinikum Wuerzburg AöR, Wuerzburg
Registry updated 2026-08-12
NCT07680452
Clinical Study on High-fiber Diet and Short-term Fasting in Melanoma Under Immunotherapy With Checkpoint Inhibition
Trial Treatment · Charite University, Berlin, Germany
Charité Universitätsmedizin Berlin, Berlin
Registry updated 2026-07-29
NCT06264180
VO and Nivolumab vs Physician's Choice in Advanced Melanoma That Progressed on Anti-PD-1 & Anti-CTLA-4 Drugs [IGNYTE-3]
Trial Treatment · Phase 3 · Replimune, Inc.
Charite Research Organisation GmbH, Berlin · Universitaetsklinikum Carl Gustav Carus Dresden an der Technischen Universitaet Dresden AöR, Dresden · HELIOS Klinikum Erfurt GmbH, Erfurt · Universitaetsklinikum Essen (AoR), Essen · Universitaetsklinikum Frankfurt AöR, Frankfurt Am Main · University Medical Center Hamburg-Eppendorf, Hamburg · Universitaetsklinikum Heidelberg AöR, Heidelberg · Universitaetsklinikum Schleswig-Holstein AöR, Kiel · Johannes Gutenberg University Mainz, Mainz · Klinikum der Universitaet Muenchen AöR, Munich · Universitaetsklinikum Tuebingen AöR, Tuebingen
Registry updated 2026-07-15

All Melanoma trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

Report an error