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Multiple myeloma: open trials in United States

299 open trials have a site in United States. Registry data; only the trial team decides who can take part.

  • NCT00626496

    Family Study of Lymphoproliferative Disorders

    Research · Mayo Clinic

    Mayo Clinic, Rochester

    Registry updated 2026-11-02

  • NCT02727803

    Personalized NK Cell Therapy in CBT

    Trial Treatment · Phase 2 · M.D. Anderson Cancer Center

    M D Anderson Cancer Center, Houston

    Registry updated 2026-11-02

  • NCT05091372

    Registry updated 2026-11-02

  • NCT06518551

    ELEVATE-MM: Elotuzumab, Iberdomide and Dexamethasone Post Idecabtagene Vicleucel in Relapsed and Refractory Multiple Myeloma

    Trial Treatment · Phase 1 · Omar Nadeem, MD

    Dana-Farber Cancer Institute, Boston · Beth Israel Deaconess Medical Center, Boston · Brigham and Women's Hospital, Boston

    Registry updated 2026-11-02

  • NCT06904066

    Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Participant-specific Neoantigens in Patients With Hematologic Malignancies

    Trial Treatment · Phase 1 · National Cancer Institute (NCI)

    National Institutes of Health Clinical Center, Bethesda

    Registry updated 2026-11-02

  • NCT07099391

    A Study of Dara-RVd and Teclistamab-RVd in People With Multiple Myeloma

    Trial Treatment · Phase 1/2 · Memorial Sloan Kettering Cancer Center

    Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities), Basking Ridge · Memorial Sloan Kettering Cancer Center @ Suffolk-Commack (Limited Protocol Activities), Commack · Memorial Sloan Kettering Westchester (Limited Protocol Activities), Harrison · Memorial Sloan Kettering Monmouth (Limited Protocol Activities), Middletown · Memorial Sloan Kettering Bergen (Limited Protocol Activities), Montvale · Memorial Sloan Kettering Cancer Center (All Protocol Activities), New York · Memorial Sloan Kettering Nassau (Limited Protocol Activities), Uniondale

    Registry updated 2026-11-02

  • NCT07341867

    Systemic Anti-Cancer Therapy Dose Modifications for Individuals With Duffy Null Phenotype

    Trial Treatment · Phase 1 · Andrew Hantel, MD

    Dana-Farber Cancer Institute, Boston · The Christ Hospital Cancer Center-Research, Cincinnati

    Registry updated 2026-11-02

  • NCT07776964

    Monitoring for CardioToxicity Using WeArable deVices While Undergoing cancEr Treatments (MCT-WAVE)

    Trial Treatment · University of Minnesota

    M Health Fairview Clinics and Surgery Center, Minneapolis

    Registry updated 2026-11-02

  • NCT03412877

    Administration of Autologous T-Cells Genetically Engineered to Express T-Cell Receptors Reactive Against Neoantigens in People With Metastatic Cancer

    Trial Treatment · Phase 2 · National Cancer Institute (NCI)

    National Institutes of Health Clinical Center, Bethesda

    Registry updated 2026-10-30

  • NCT05363111

    Radioimmunotherapy (111Indium/225Actinium-DOTA-daratumumab) for the Treatment of Relapsed/Refractory Multiple Myeloma

    Trial Treatment · Phase 1 · City of Hope Medical Center

    City of Hope Medical Center, Duarte

    Registry updated 2026-10-30

  • NCT05519085

    A Study to Evaluate Mezigdomide, Bortezomib and Dexamethasone (MEZIVd) Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) in Participants With Relapsed or Refractory Multiple Myeloma (RRMM)

    Trial Treatment · Phase 3 · Celgene

    Abilene · Albuquerque · Allentown · Ann Arbor · Athens · Aurora · Baltimore · Baton Rouge · Boston · Buffalo · Cincinnati · Cleveland · Cleveland · Coral Springs · Detroit · Durham · East Brunswick · Farmington · Fort Myers · Fredericksburg · Garden City · Germantown · Hattiesburg · Houston · Jackson · Lake Success · Los Alamitos · Madison · Marietta · Mayfield Heights · Minneapolis · New Haven · New Hyde Park · New Orleans · New York · Norfolk · Orange City · Ridgewood · Roanoke · Rochester · Salt Lake City · San Antonio · San Antonio · San Diego · Seattle · Seattle · Shirley · Shreveport · Spokane · The Bronx · Vancouver · West Hollywood · West Palm Beach · Westwood · Williamsville · York

    Registry updated 2026-10-30

  • NCT05974150

    Real World Treatment Experience of Patients With Breast, Lung, Ovarian, Multiple Myeloma, or Acute Myelogenous Leukemia Using Remote Symptom Monitoring

    Research · Carevive Systems, Inc.

    Cleveland Clinic Mercy Hospital, Canton · Univeristy of North Carolina at Chapel Hill, Chapel Hill · University Hospitals Seidman Cancer Center, Cleveland · Duke, Durham · Northshore University Health System, Evanston · Tri-County Hematology & Oncology Associates, Inc., Massillon · Yale Cancer Center, New Haven

    Registry updated 2026-10-30

  • NCT06106945

    AZD0305 as Monotherapy or in Combination With Anticancer Agents in Participants With Multiple Myeloma

    Trial Treatment · Phase 1/2 · AstraZeneca

    Ann Arbor · Atlanta · Boston · Duarte · Fairfax · Irvine · New York · Philadelphia · St Louis

    Registry updated 2026-10-30

  • NCT06433947

    Study to Assess Safety and Tolerability of OPN-6602 in Subjects With Relapsed and/or Refractory Multiple Myeloma

    Trial Treatment · Phase 1 · Opna Bio LLC

    Emory Winchip Cancer Center, Atlanta · Dana-Farber Cancer Institute, Boston · University of North Carolina Hospitals at Hillsborough, Chapel Hill · Karmanos Cancer Institute, Detroit · Banner MD Anderson, Gilbert · START | Midwest, Grand Rapids · UC San Diego Moores Cancer Center, La Jolla · University of Rochester Medical Center, Rochester · Huntsman Cancer Center Institute University of Utah, Salt Lake City · Fred Hutchinson Cancer Center, Seattle · Stanford Cancer Institute, Stanford · University of Kansas Clinical Research Center, Westwood

    Registry updated 2026-10-30

  • NCT06960993

    Mosaic Trial for Stem Cell Transplant Recipients

    Trial Treatment · Northwestern University

    Northwestern University Feinberg School of Medicine, Chicago · Hackensack Meridian Health, Nutley · Georgetown University School of Medicine, Washington D.C.

    Registry updated 2026-10-30

  • NCT07280013

    A Study to Learn About the Effects of Cemsidomide in Combination With Elranatamab in Relapsed/Refractory Multiple Myeloma Subjects

    Trial Treatment · Phase 1 · C4 Therapeutics, Inc.

    Winship Cancer Institute, Emory University, Atlanta · University of Maryland Greenbaum Comprehensive Cancer Center, Baltimore · Perlmutter Cancer Center at NYU Langone Hospital, Brooklyn · Ohio State University Comprehensive Cancer Center, Columbus · Baylor University Medical Center, Dallas · Duke Cancer Center, Durham · Banner MD Anderson Cancer Center, Gilbert · START | Midwest, Grand Rapids · Houston Methodist Hospital, Houston · Indiana University, Indianapolis · Dartmouth Hitchcock Medical Center, Lebanon · Norton Cancer Institute St. Matthews, Louisville · Loyola University Medical Center, Maywood · University of Miami, Miami · Memorial Sloan-Kettering Cancer Center, New York · University of Nebraska, Omaha · UC Davis Comprehensive Cancer Center, Sacramento · Huntsman Cancer Institute/University of Utah, Salt Lake City · UCLA Health, Jonsson Comprehensive Cancer Center, Santa Monica

    Registry updated 2026-10-30

  • NCT07284758

    A Study to Evaluate the Efficacy of Cemsidomide + Dexamethasone in Participants With Relapsed/Refractory Multiple Myeloma

    Trial Treatment · Phase 2 · C4 Therapeutics, Inc.

    University of Michigan, Ann Arbor · Winship Cancer Institute, Emory University, Atlanta · Beth Israel Deaconess Medical Center, Boston · Massachusetts General Hospital, Boston · Dana-Farber Cancer Institute, Boston · UNC Hospitals Adult Oncology Clinics, Chapel Hill · Karmanos Cancer Institute, Detroit · City of Hope, Duarte · START | Midwest, Grand Rapids · Clearview Cancer Institute, Huntsville · Indiana University Health, Indianapolis · University of Iowa, Iowa City · Mayo Clinic Florida, Jacksonville · University of Wisconsin Carbone Cancer Center, Madison · MCW-Clinical Cancer Center at Froedtert Hospital Campus, Milwaukee · Tennessee Oncology, Nashville · Memorial Sloan-Kettering Cancer Center, New York · The Tisch Cancer Institute/Mount Sinai, New York · University of Nebraska Medical Center, Omaha · Mayo Clinic - Arizona, Phoenix · Mayo Clinic Minnesota, Rochester · START | San Antonio, San Antonio · HonorHealth, Scottsdale · Washington University, Siteman Cancer Center, St Louis · Berenson Cancer Center, West Hollywood

    Registry updated 2026-10-30

  • NCT02333604

    Cancer Experience Registry (CER) for Cancer Patients and Caregivers

    Research · Cancer Support Community, Research and Training Institute, Philadelphia

    Cancer Support Community Research & Training Institute, Washington D.C.

    Registry updated 2026-10-29

  • NCT03616483

    The Indiana Myeloma Registry

    Research · Indiana University

    Indiana University Simon Cancer Center, Indianapolis

    Registry updated 2026-10-29

  • NCT06103838

    18F-Fluciclovine PET/CT in Multiple Myeloma

    Trial Treatment · Phase 2 · National Cancer Institute (NCI)

    National Institutes of Health Clinical Center, Bethesda

    Registry updated 2026-10-29

  • NCT06615479

    A Study to Compare the Efficacy and Safety of BMS-986393 Versus Standard Regimens in Adult Participants With Relapsed or Refractory and Lenalidomide-exposed Multiple Myeloma (QUINTESSENTIAL-2)

    Trial Treatment · Phase 3 · Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

    Winship Cancer Institute, Emory University, Atlanta · University of Alabama at Birmingham, Birmingham · Boston Medical Center, Boston · Charleston · Levine Cancer Institute, Charlotte · Cleveland Clinic, Cleveland · University of Texas - MD Anderson Cancer Center, Houston · Baptist MD Anderson Cancer Center, Jacksonville · UCLA Hematology/Oncology - Santa Monica, Los Angeles · University of Miami Hospital and Clinics, Sylvester Cancer Center, Miami · Medical College of Wisconsin, Milwaukee · Minneapolis · Weill Cornell Medical College, New York · University of California, Irvine (UCI) Health - UC Irvine Medical Center, Orange · Orlando · Philadelphia · AHN West Penn Hospital, Pittsburgh · Huntsman Cancer Institute, Salt Lake City · Louisiana State University Health Sciences Shreveport, Shreveport · Stony Brook · Georgetown University Medical Center, Washington D.C.

    Registry updated 2026-10-29

  • NCT01137643

    Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic Cancer

    Research · UNC Lineberger Comprehensive Cancer Center

    Lineberger Comprehensive Cancer Center at University of North Carolina, Chapel Hill, Chapel Hill

    Registry updated 2026-10-28

  • NCT06487247

    HEME Home Transfusion Program

    Trial Treatment · Dana-Farber Cancer Institute

    Dana-Farber Cancer Institute, Boston · Brigham and Women's Hospital, Boston

    Registry updated 2026-10-28

  • NCT00900198

    Collection of Tissue Samples for Cancer Research

    Research · National Cancer Institute (NCI)

    University of Michigan, Ann Arbor, Ann Arbor · Emory University, Atlanta · University of Colorado Denver, Aurora · Johns Hopkins University, Baltimore · National Institutes of Health Clinical Center, Bethesda · Roswell Park Cancer Institute, Buffalo · Medical University of South Carolina, Charleston · University of Virginia, Charlottesville, Charlottesville · Ohio State University, Columbus · Indiana University - Purdue, Indianapolis · University of Iowa, Iowa City · University of Pittsburgh Medical Center, Pittsburgh · UC Davis, Sacramento · University of Utah, Salt Lake City · Fred Hutchinson, Seattle · Washington University St. Louis, St Louis

    Registry updated 2026-10-27

  • NCT05623020

    A Study to Learn About the Effects of the Combination of Elranatamab, Daratumumab and Lenalidomide Compared With Daratumumab, Bortezomib, Lenalidomide, and Dexamethasone in Patients With Newly Diagnosed Multiple Myeloma Who Are Not Candidates for Transplant

    Trial Treatment · Phase 3 · Pfizer

    MSK Basking Ridge., Basking Ridge · MSK Commack., Commack · Sylvester Comprehensive Cancer Center- The Lennar Foundation Medical Center, Coral Gables · Sylvester Comprehensive Cancer Center - Coral Springs, Coral Springs · Gulf Health Hospitals, Inc. d/b/a Infirmary Cancer Care - Malbis, Daphne · Gulf Health Hospitals, Inc. d/b/a Thomas Medical Center, Daphne · University of Miami Hospital and Clinics Deerfield Beach, Deerfield Beach · Sylvester Comprehensive Cancer Center- Doral, Doral · Gulf Health Hospitals, Inc. d/b/a Infirmary Cancer Care - Fairhope, Fairhope · MSK Westchester., Harrison · Sylvester Comprehensive Cancer Center - Hollywood, Hollywood · The University of Texas MD Anderson Cancer Center, Houston · Jupiter Medical Center/Anderson Family Cancer Institute, Jupiter · NHO Revive Research Institute, LLC, Lincoln · Sylvester Comprehensive Cancer Center*, Miami · Sylvester Comprehensive Cancer Center - Kendall, Miami · University of Miami Hospital and Clinics, Miami · MSK Monmouth., Middletown · Mobile Infirmary Medical Center, Mobile · Mobile Infirmary Association d/b/a Mobile Infirmary Medical Center, Mobile · Gulf Health Hospitals, Inc. d/b/a Infirmary Cancer Care - Mobile, Mobile · MSK Bergen., Montvale · Memorial Sloan Kettering Cancer Center - David H. Koch Center for Cancer Care (74th Street)., New York · Memorial Sloan Kettering Cancer Center - Main Campus, New York · Sylvester Comprehensive Cancer Center - Sole Mia, North Miami · Sylvester Comprehensive Cancer Center Plantation, Plantation · Renown Health Medical Oncology, Reno · Renown Regional Medical Center, Reno · Renown Office of Clinical Research, Reno · LDS Hospital, Salt Lake City · Intermountain Cancer Center St. George, St. George · St. George Regional Hospital, St. George · MSK Nassau., Uniondale

    Registry updated 2026-10-27

All Multiple myeloma trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

Under construction, not live – Multiple myeloma trials in United States – Frontlight Research