Myelodysplastic syndromes: open trials in Brazil

• NCT06499285

  A Study of Elritercept to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Who Need Regular Blood Transfusions

  Trial Treatment · Phase 3 · Takeda

  Hosptial Erasto Gaertner, Curitiba · FundaAAo Doutor Amaral Carvalho, Jaú · Instituto Joinvilense de Hematologia e Oncologia, Joinville · Hospital Mae de Deus, Clinical Research Unit - Cancer Institute, Porto Alegre · Porto Alegre Clinical Hospital (HCPA), Porto Alegre · Pontifical University Of Rio Grande Do Sul (PUCRS) - St. Luke Hospital, Porto Alegre · Americas Institute, Rio de Janeiro · Cepho- Fmabc, Santo André · Sao Jose do Rio Preto Regional Faculty of Medicine Foundation, São José do Rio Preto · Santa Casa of Mercy of Santos, São Paulo · Portuguese Charity of Sao Paulo, Clinical Hematology / Oncology Center, São Paulo · Hospital A.C.Camargo ("Antonio Prudente" Foundation), São Paulo

  Registry updated 2026-11-06

• NCT07422480

  A Study to Compare Elritercept With Epoetin Alfa to Treat Anemia in Adults With Lower Risk Myelodysplastic Syndromes (LR-MDS) Who Need Regular Blood Transfusions

  Trial Treatment · Phase 3 · Takeda

  Hospital Amaral Carvalho (HAC), Jaú · Centro de Hematologia e Oncologia (CHO), Joinville · Porto Alegre Clinical Hospital (HCPA), Porto Alegre · Hospital Mae de Deus, Clinical Research Unit - Cancer Institute, Porto Alegre · D'OR Institute for Research and Education, Salvador · Irmandade da Santa Casa da Misericordia de Santos (ISCMS), Santos · Portuguese Charity of Sao Paulo, Clinical Hematology / Oncology Center, São Paulo · Hospital 9 de Julho (Rede Americas/DASA), São Paulo

  Registry updated 2026-11-06

• NCT06465953

  Ivosidenib (IVO) Monotherapy and Azacitidine (AZA) Monotherapy in Patients With Hypomethylating Agent (HMA) Naive Myelodysplastic Syndromes (MDS) With an IDH1 Mutation

  Trial Treatment · Phase 3 · Institut de Recherches Internationales Servier

  Liga Paranaense de Combate ao Cancer - Hospital Erasto Gaertner, Curitiba · Centro de Pesquisas Clínicas da Fundação Doutor Amaral Carvalho, São Paulo · Instituto Nacional do Câncer, São Paulo · Real E Benemerita Associacao Portuguesa de Sao Paulo, São Paulo · Casa de Saude Santa Marcelina, São Paulo · Hospital das Clinicas da Faculdade de Medicina da USP, São Paulo · Sociedade Beneficente Israelita Brasileira Hospital Albert Einstein, São Paulo · Centro de Pesquisa Clínica - Hospital Nove de Julho, São Paulo

  Registry updated 2026-09-03

• NCT06299462

  PTCy and ATG for MSD and MUD Transplants

  Trial Treatment · Phase 1/2 · Instituto Nacional de Cancer, Brazil

  Instituto Nacional de Câncer, Rio de Janeiro

  Registry updated 2025-02-25

All Myelodysplastic syndromes trials and the map

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