Neuromyelitis optica (NMOSD): open trials in United States

• NCT06780709

  Impact of a Structured Wellness Behavioral Intervention on Quality of Life in NMOSD

  Trial Treatment · Icahn School of Medicine at Mount Sinai

  Corinne Goldsmith Dickinson Center for MS at Mount Sinai, New York

  Registry updated 2026-11-02

• NCT05966467

  Registry of Patients With AQP4+ NMOSD Treated With Alexion C5 Inhibitor Therapies

  Research · Alexion Pharmaceuticals, Inc.

  Boston · Chapel Hill · Columbus · Milwaukee · Plano · Washington D.C.

  Registry updated 2026-10-13

• NCT05199688

  A Study to Evaluate Pharmacokinetics, Efficacy, Safety, Tolerability, and Pharmacodynamics of Satralizumab in Pediatric Patients With Aquaporin-4 Antibody Positive Neuromyelitis Optica Spectrum Disorder (NMOSD)

  Trial Treatment · Phase 3 · Hoffmann-La Roche

  Children's Hospital Colorado, Denver

  Registry updated 2026-10-01

• NCT07010302

  Rituximab Versus Ravulizumab, Inebilizumab, Satralizumab, and Eculizumab in NMOSD

  Trial Treatment · Phase 4 · Massachusetts General Hospital

  Massachusetts General Hospital, Boston · Brigham and Women's Hospital, Boston

  Registry updated 2026-09-24

• NCT07573332

  A Safety and Tolerability Study of CC- 97540 (BMS-086353) in Anti-Aquaporin 4 Antibody Positive Neuromyelitis Optica Patients

  Trial Treatment · Phase 1 · University of Texas Southwestern Medical Center

  UT Southwestern, Dallas

  Registry updated 2026-07-17

• NCT05549258

  Study of Inebilizumab in Pediatric Subjects With Neuromyelitis Optica Spectrum Disorder

  Trial Treatment · Phase 2 · Amgen

  Massachusetts General Hospital, Boston · University of Texas Southwestern Medical Center, Dallas · UCSD Altman Clinical and Translational Research Institute Building, La Jolla · Loma Linda University Children's Hospital - PIN, Loma Linda

  Registry updated 2025-12-05

• NCT05566769

  Performance and Safety of a Digital Tool for Unsupervised Self-assessment of NMOSD

  Trial Treatment · Ad scientiam

  Johns Hopkins Outpatient Center (now called Levi Watkins, Jr., M.D., Outpatient Center), Baltimore · Massachussets General Hospital, Boston · University of North Carolina at Chapel Hill, Chapel Hill · NorthShore University HealthSystem, Evanston · CC Lou Ruvo Center for Brain Health, Las Vegas · University of Southern California, Los Angeles · Oklahoma Medical Research Foundation, Oklahoma City · University of California Davis Health, Sacramento · University of South Florida, Tampa · Washington University in St. Louis, Washington

  Registry updated 2025-04-10

All Neuromyelitis optica (NMOSD) trials and the map

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