Pancreatic cancer: open trials in Canada

58 open trials have a site in Canada. Registry data; only the trial team decides who can take part.

NCT06983743
A Study of ERAS-0015 in Patients With Advanced or Metastatic Solid Tumors
Trial Treatment · Phase 1 · Erasca, Inc.
The Princess Margaret Cancer Center, Toronto
Registry updated 2026-11-06
NCT07644559
A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Pancreatic Cancer
Trial Treatment · Phase 2 · Verastem, Inc.
Sunnybrook Health Sciences Centre, Toronto · Princess Margaret Cancer Center, Toronto
Registry updated 2026-11-06
NCT07090499
A Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced Solid Tumors
Trial Treatment · Phase 1 · Pfizer
McGill University Health Centre, Montreal · Princess Margaret Cancer Centre, Toronto
Registry updated 2026-11-05
NCT06760819
A Study to Learn More About How Well Treatment With Sevabertinib (BAY 2927088) Tablets Works and How Safe it is in Participants Who Have a Solid Tumor With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)
Trial Treatment · Phase 2 · Bayer
Queen Elizabeth II Health Sciences Centre | Oncology, Halifax · Research Institute of the McGill University Health Centre | Women Health's Research Unit, Montreal · Princess Margaret Cancer Centre | Medical Oncology and Hematology, Toronto
Registry updated 2026-11-04
NCT07492680
A Study of Navlimetostat (BMS-986504) Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5)
Trial Treatment · Phase 2 · Bristol-Myers Squibb
Toronto · Toronto · Vancouver
Registry updated 2026-11-04
NCT04924075
Belzutifan/MK-6482 for the Treatment of Advanced Pheochromocytoma/Paraganglioma (PPGL), Pancreatic Neuroendocrine Tumor (pNET), Von Hippel-Lindau (VHL) Disease-Associated Tumors, Advanced Gastrointestinal Stromal Tumor (wt GIST), or Solid Tumors With HIF-2α Related Genetic Alterations (MK-6482-015)
Trial Treatment · Phase 2 · Merck Sharp & Dohme LLC
Arthur J.E. Child Comprehensive Cancer Centre (Site 0203), Calgary · Princess Margaret Cancer Centre (Site 0202), Toronto
Registry updated 2026-11-03
NCT07166601
M0324 as Monotherapy and in Combination With Pembrolizumab or Chemotherapy in Participants With Selected Advanced Solid Tumors
Trial Treatment · Phase 1 · EMD Serono Research & Development Institute, Inc.
Princess Margaret Cancer Centre, Toronto
Registry updated 2026-11-02
NCT06943755
Zanzalintinib Versus Everolimus in Participants With Locally Advanced or Metastatic Neuroendocrine Tumors
Trial Treatment · Phase 2/3 · Exelixis
Verspeeten Family Cancer Center - London Health Sciences Centre, London · The Ottawa Hospital Cancer Center, Ottawa · Sunnybrook Health Sciences Centre, Toronto
Registry updated 2026-10-30
NCT07387263
Mainstreaming Genetics: Evaluation of a Digital Application to Scale and Spread Oncologist-initiated Genetic Testing
Trial Treatment · Unity Health Toronto
Mount Sinai Hospital, Toronto · Sunnybrook Hospital, Toronto
Registry updated 2026-10-30
NCT07522073
A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma
Trial Treatment · Phase 3 · Incyte Corporation
Hamilton · Kingston · Montreal · Québec · Toronto
Registry updated 2026-10-30
NCT04970056
Pancreatic Cancer Early Detection Consortium
Research · Arbor Research Collaborative for Health
McGill University Health Centre, Montreal · University Health Network, Toronto · British Columbia Cancer Agency, Vancouver
Registry updated 2026-10-29
NCT06428409
A Clinical Study of MK-2870 Alone or With Other Treatments to Treat Gastrointestinal Cancers (MK-9999-02A)
Trial Treatment · Phase 1/2 · Merck Sharp & Dohme LLC
Centre Hospitalier de l'Université de Montréal-Unit for Innovative Therapies (Site 0022), Montreal · McGill University Health Centre (Site 0023), Montreal · The Ottawa Hospital Cancer Centre (Site 0027), Ottawa
Registry updated 2026-10-29
NCT04421820
BOLD-100 in Combination With FOLFOX With or Without Bevacizumab for the Treatment of Advanced, Solid Tumours
Trial Treatment · Phase 1/2 · Bold Therapeutics, Inc.
Cross Cancer Institue, Edmonton · Juravinski Cancer Centre, Hamilton · Jewish General Hospital, Montreal · McGill University Health Centre Glen Site, Montreal · The Ottawa Hospital Cancer Centre, Ottawa · Princess Margaret Cancer Centre, Toronto
Registry updated 2026-10-28
NCT06172478
A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
Trial Treatment · Phase 2 · Daiichi Sankyo
Cross Cancer Institute, Edmonton · Sunnybrook Research Institute, Toronto · Princess Margaret Cancer Centre, Toronto · BC Cancer - Vancouver, Vancouver
Registry updated 2026-10-26
NCT07252232
Study of Daraxonrasib (RMC-6236) in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC)
Trial Treatment · Phase 3 · Revolution Medicines, Inc.
McGill University Health Centre, Montreal · Princess Margaret Cancer Centre - University Health Network, Toronto
Registry updated 2026-10-23
NCT05687123
Testing the Addition of Sunitinib Malate to Lutetium Lu 177 Dotatate (Lutathera) in Pancreatic Neuroendocrine Tumors
Trial Treatment · Phase 1 · National Cancer Institute (NCI)
University Health Network, Princess Margaret Hospital, Toronto
Registry updated 2026-10-20
NCT07360314
Anti-Ly6E Exatecan ADC M7437 in Advanced Solid Tumors
Trial Treatment · Phase 1 · EMD Serono Research & Development Institute, Inc.
Princess Margaret Cancer Centre, Toronto · BC Cancer - Vancouver - BC Cancer Agency, Vancouver
Registry updated 2026-10-20
NCT06885034
A Study to Test the Safety and Effectiveness of GSK5764227, Alone or With Other Treatments, in Participants With Advanced Gastrointestinal Cancers That Cannot be Surgically Removed (EMBOLD PanGI-201)
Trial Treatment · Phase 1/2 · GlaxoSmithKline
Calgary · Montreal · Sherbrooke · Toronto
Registry updated 2026-10-19
NCT06989437
A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue
Trial Treatment · Phase 2/3 · Pfizer
Arthur J.E. Child Comprehensive Cancer Centre, Calgary · CIUSSS- saguenay-Lac-Saint-Jean, Chicoutimi · Centre Intégré de Santé et de Services Sociaux de la Montérégie-Centre, Greenfield Park · Jewish General Hospital, Montreal · The Ottawa Hospital - General Campus, Ottawa · Unity Health Toronto, St. Michael's Hospital, Toronto · Princess Margaret Cancer Centre - University Health Network, Toronto · Sunnybrook Research Institute, Toronto
Registry updated 2026-10-14
NCT07261631
Phase I Study of [177Lu]Lu-DFC413 in Patients With Solid Tumors
Trial Treatment · Phase 1 · Novartis Pharmaceuticals
Montreal
Registry updated 2026-10-09
NCT04429542
Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors
Trial Treatment · Phase 1 · Bicara Therapeutics
Centre Hospitalier de l'Universite de Montreal (CHUM), Montreal · Princess Margaret Cancer Centre, Toronto
Registry updated 2026-10-06
NCT07491445
Study of Daraxonrasib and Daraxonrasib + GnP as First-line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma
Trial Treatment · Phase 3 · Revolution Medicines, Inc.
McGill University - Dept. Oncology Clinical Research Program, Montreal · Princess Margaret Cancer Centre, Toronto · Sunnybrook Research Institute, Toronto
Registry updated 2026-10-02
NCT06219941
AZD0901 in Participants With Advanced Solid Tumours Expressing Claudin18.2
Trial Treatment · Phase 2 · AstraZeneca
Kingston · Montreal · Sherbrooke · Toronto
Registry updated 2026-09-30
NCT06574620
Using Tumour DNA and Proteins to Better Understand How Pancreatic Cancer Responds to Treatment
Trial Treatment · British Columbia Cancer Agency
BC Cancer, Vancouver
Registry updated 2026-09-16
NCT07255001
Using Strength Tests to Better Understand How Pancreatic Cancer Affects Muscle Mass and Quality of Life
Trial Treatment · British Columbia Cancer Agency
BC Cancer, Vancouver
Registry updated 2026-09-15

All Pancreatic cancer trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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