Pancreatic cancer trials in Germany

In Germany 53 Also abroad 1094

53 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 12 November 2026. Ask the study team whether a trial fits you.

Phase 3Taking people
Phase 3 Study of Investigator Choice of Chemotherapy with or without Zoldonrasib as First-line Treatment in Metastatic KRAS G12D-mutated Pancreatic Adenocarcinoma
Where
Berlin, Bochum, Dresden, Frankfurt am Main, Hamburg, Heidelberg, Heilbronn, Munich, Ulm
Age
18 years and over
People
281 worldwide
Run by
Revolution Medicines Inc.
See details and how to join2025-524928-21-00
Phase 3Taking people
A Randomized, Double-Blind, Phase 3 Study of Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D–Mutated Metastatic Pancreatic Ductal Adenocarcinoma (DAWN-303)
Where
Berlin, Bochum, Bonn, Cologne, Dresden, Duesseldorf, Essen, Frankfurt am Main, Freiburg im Breisgau, Goettingen, Halle Saale, Hamburg, Leipzig, Munich, Nuremberg, Ulm
Age
18 years and over
People
239 worldwide
Run by
Incyte Corp.
See details and how to join2025-525009-18-00
Phase 1/2Taking people
Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors
Where
Cologne, Esslingen am Neckar, Moers, Nuremberg
Age
18 years and over
People
534 worldwide
Run by
Revolution Medicines, Inc.
See details and how to joinNCT06128551
Phase 1Taking people
A phase I open-label, multi-center study to evaluate the safety, tolerability, dosimetry, and preliminary activity of [177Lu]Lu-DFC413 and safety and imaging properties of [68Ga]Ga-NNS309 in patients with solid tumors
Where
Essen
Age
18 years and over
People
62 worldwide
Run by
Novartis Pharma AG
See details and how to join2025-521702-18-00
No phaseTaking people
ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation
Where
Hamburg, Heilbronn, Munich
Age
18 years and over
People
2,285 worldwide
Run by
Guardant Health, Inc.
See details and how to joinNCT05059444
Phase 1/2Taking people
Master protocol of TCR-modified T cell therapy targeting HLA-restricted KRAS antigen administered in adult patients with metastatic or locally advanced PDAC
Where
Berlin, Dresden, Heidelberg, Leipzig, Munich, Tuebingen
Age
18 years and over
People
57 worldwide
Run by
Anocca AB
See details and how to join2024-513900-32-00
Phase 1/2Taking people
A Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors
Where
Dresden, Essen, Frankfurt, Ulm, Würzburg
Age
18 years and over
People
1,109 worldwide
Run by
Bristol-Myers Squibb
See details and how to joinNCT04895709
No phaseTaking people
ToPanc Trial: Survival After Total Versus Partial Pancreaticoduodenectomy for Adenocarcinoma of the Pancreatic Head, Distal Cholangiocarcinoma, and Ampullary Cancer
Where
Münster, Ulm
Age
18 years and over
People
170 worldwide
Run by
Insel Gruppe AG, University Hospital Bern
See details and how to joinNCT06801899
Phase 1Taking people
AMG 410 Alone and in Combination With Other Agents in Participants With KRAS Altered Advanced or Metastatic Solid Tumors
Where
Essen
Age
18 years and over
People
434 worldwide
Run by
Amgen
See details and how to joinNCT07094113
Phase 1Taking people
Phase I Study of [177Lu]Lu-NNS309 in Patients With Pancreatic, Lung, Breast and Colorectal Cancers
Where
Cologne, Essen, München, Rostock
Age
18 years to 100 years
People
162 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT06562192
No phaseNot yet taking people in Germany
Modulated Mid-frequency Whole-body Electromyostimulation and Nutritional Therapy in Gastrointestinal Cancer Patients
Where
Cologne
Age
18 years and over
People
88
Run by
University of Cologne
See details and how to joinNCT06414122
Phase 1Taking people
A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors
Where
Berlin
Age
18 years and over
People
714 worldwide
Run by
Seagen, a wholly owned subsidiary of Pfizer
See details and how to joinNCT05208762 · EU 2023-506604-18-00
Phase 2Taking people
A Phase II trial of ginisortamab in participants with metastatic pancreatic ductal adenocarcinoma
Where
Munich, Ulm
Age
18 years and over
People
43 worldwide
Run by
Cancer Research UK
See details and how to join2024-514129-43-00
Phase 2/3Taking people
SIL204-SL Treatment for Locally Advanced Pancreatic Cancer
Where
Erlangen, Munich, Ulm
Age
18 years and over
People
10
Run by
Silexion Therapeutics Ltd.
See details and how to join2025-525157-39-00
Phase 3Taking people
Short or long NAT for BR/LAPC (ADVANTAGE Trial)
Where
Frankfurt am Main, Hamburg, Heidelberg
Age
18 years and over
People
754 worldwide
Run by
Vastra Gotalandsregionen
See details and how to join2022-502117-29-00
Phase 2/3Not yet taking people in Germany
68Ga-FAPI-46 PET for imaging of gastrointestinal cancers: A prospective interventional single-arm clinical trial (FAPI-PET-GI)
Where
Essen, Muenster
Age
18 years and over
People
150
Run by
Universitaetsklinikum Essen AöR
See details and how to join2023-506030-70-00
Phase 1Taking people
Phase I open-label, multi-center study to evaluate the safety, tolerability, dosimetry, and preliminary activity of [177Lu]Lu-NNS309 in patients with pancreatic, lung, breast and colorectal cancers.
Where
Cologne, Essen, Munich, Rostock
Age
18 years and over
People
76 worldwide
Run by
Novartis Pharma AG
See details and how to join2023-510356-23-00
Phase 3Taking people
Intensified treatment in patients with oligometastatic pancreatic cancer - multimodal surgical treatment versus systemic chemotherapy alone: a randomized controlled trial - METAPANC
Where
Aachen, Berlin, Bochum, Cologne, Dresden, Erlangen, Essen, Frankfurt Am Main, Freiburg im Breisgau, Giessen, Goettingen, Halle Saale, Hamburg, Hanover, Heidelberg, Lübeck, Mainz, Mannheim, Munich, Münster, Nuremberg, Regensburg, Ulm, Wuerzburg
Age
18 years and over
People
500 worldwide
Run by
Universitaetsmedizin Goettingen
See details and how to join2023-503558-10-00
No phaseTaking people
The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study
Where
Tübingen
Age
18 years and over
People
8,000 worldwide
Run by
UMC Utrecht
See details and how to joinNCT04075305
Phase 3Taking people
Pancreatic Head Resection or Total Pancreatectomy With Islet Autotransplantation in Patients With Periampullary Cancer and High Risk Profile for the Development of Postoperative Pancreatic Fistula
Where
Dresden
Age
18 years and over
People
32
Run by
Technische Universität Dresden
See details and how to joinNCT05843877 · EU 2023-507773-17-00
Phase 4Taking people
Effect on Body Movement and Mental Skills in Patients Who Received Gadolinium-based Contrast Media for Magnetic Resonance Examination Multiple Times Within 5 Years
Where
Berlin, Tübingen
Age
18 years to 64 years
People
2,076 worldwide
Run by
Guerbet
See details and how to joinNCT04373564
No phaseTaking people
Assessing Pancreatic Fistula Rates After Distal Pancreatectomy Using AEON Endostapler
Where
Heidelberg
Age
18 years and over
People
110
Run by
University Hospital Heidelberg
See details and how to joinNCT06764134
No phaseTaking people
Comparison of the Physical Activity in Cancer Patients Assessed by Questionnaire and Motion Tracker
Where
Greifswald
Age
18 years and over
People
60
Run by
University Medicine Greifswald
See details and how to joinNCT05501379
Phase 2/3Taking people
Study of Nab-Paclitaxel and Gemcitabine With or Without SBP-101 in Pancreatic Cancer
Where
Berlin, Dresden, Hamburg, Tuebingen, Weiden I D Opf
Age
18 years and over
People
600 worldwide
Run by
Panbela Therapeutics, Inc.
See details and how to joinNCT05254171 · EU 2024-514714-12-00
No phaseTaking people
Stereotactic Body Radiotherapy in Patients With Rare Oligometastatic Cancers (OligoRARE)
Where
Hamburg
Age
18 years and over
People
200 worldwide
Run by
European Organisation for Research and Treatment of Cancer - EORTC
See details and how to joinNCT04498767