Pancreatic cancer trials in Italy

In Italy 92 Also abroad 1095

92 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 12 November 2026. Ask the study team whether a trial fits you.

Phase 1/2Taking people
Phase 1b/2 Study of Anti-CEACAM5 ADC M9140 in Participants With Advanced Pancreatic Cancer (Substudy PDAC)
Where
Ancona, Milan, Naples, Padova, Pisa, Reggio Emilia, Rome
Age
18 years and over
People
26 worldwide
Run by
Merck Healthcare KGaA
See details and how to join2024-517819-74-00
Phase 3Taking people
Phase 3 Study of Investigator Choice of Chemotherapy with or without Zoldonrasib as First-line Treatment in Metastatic KRAS G12D-mutated Pancreatic Adenocarcinoma
Where
Bologna, Florence, Milan, Naples, Padova, Pisa, Rome, Verona
Age
18 years and over
People
281 worldwide
Run by
Revolution Medicines Inc.
See details and how to join2025-524928-21-00
Phase 3Taking people
A Randomized, Double-Blind, Phase 3 Study of Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D–Mutated Metastatic Pancreatic Ductal Adenocarcinoma (DAWN-303)
Where
Bologna, Brescia, Candiolo, Foggia, Milan, Naples, Pisa, Rome, Rozzano, Verona
Age
18 years and over
People
239 worldwide
Run by
Incyte Corp.
See details and how to join2025-525009-18-00
No phaseTaking people
Radiology Registry on Pancreatic Malignancies
Where
Milan
Age
18 years and over
People
1,300
Run by
IRCCS San Raffaele
See details and how to joinNCT05714111
Phase 1/2Taking people
Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors
Where
Ancona, Aviano, Meldola, Milan, Naples, Orbassano, Ravenna, Verona
Age
18 years and over
People
534 worldwide
Run by
Revolution Medicines, Inc.
See details and how to joinNCT06128551
Phase 4Taking people
Efficacy of PERT for PEI in Unresectable Pancreatic Cancer.
Where
Milan
Age
18 years and over
People
100 worldwide
Run by
Hospital Clinico Universitario de Santiago
See details and how to joinNCT06099119
Phase 4Taking people
Preventing postoperative complications in patients undergoing high-risk pancreatoduodenectomy with a bundle approach including hydrocortisone, ocreotide, and teres ligament patch (PANENCA): an international randomized controlled multicenter trial
Where
Milan, Padova, Verona
Age
18 years and over
People
460 worldwide
Run by
Amsterdam UMC Stichting
See details and how to join2024-519667-18-00
No phaseNot yet taking people in Italy
Personalised Nutritional Care in Older Patients With Pancreatic Ductal Adenocarcinoma
Where
Padova
Age
65 years and over
People
250 worldwide
Run by
Inna Chen, MD
See details and how to joinNCT07821554
Phase 2Taking people
[68Ga]BED003 PET Imaging of Fibroblast Activation Protein in Selected Oncology Indications
Where
Bergamo, Milan, Monza, Rome
Age
18 years to 79 years
People
71 worldwide
Run by
Blue Earth Diagnostics
See details and how to joinNCT07702292 · EU 2025-521983-36-00
No phaseTaking people
ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation
Where
Meldola, Reggio Emilia, Roma
Age
18 years and over
People
2,285 worldwide
Run by
Guardant Health, Inc.
See details and how to joinNCT05059444
Phase 1Taking people
A Study of ASP2138 Given by Itself or Given With Other Cancer Treatments in Adults With Stomach Cancer, Gastroesophageal Junction Cancer, or Pancreatic Cancer
Where
Milan, Rozzano, Verona
Age
18 years and over
People
398 worldwide
Run by
Astellas Pharma Global Development, Inc.
See details and how to joinNCT05365581 · EU 2023-504514-29-00
Phase 4Taking people
Remimazolam versus propofol for deep sedation during Endoscopic Ultrasound (EUS) procedures. A randomized controlled trial.
Where
Milan
Age
18 years and over
People
332
Run by
Ospedale San Raffaele S.r.l.
See details and how to join2025-521784-12-00
Phase 3Taking people
Gemcitabine Plus Nab-paclitaxel as Switch Maintenance Versus Continuation of Modified FOLFIRINOX as 1st Line Chemotherapy in Patients With Advanced Pancreatic Cancer.
Where
Aviano, Bari, Brescia, Crema (CR), Cremona, Florence, Genoa, Meldola, Milan, Misterbianco, Naples, Novara, Padova, Parma, Pavia, Pesaro, Pisa, Ponderano, Prato, Ravenna, Rome, Rozzano, Tricase, Udine
Age
18 years and over
People
340
Run by
Gruppo Oncologico del Nord-Ovest
See details and how to joinNCT06897644 · EU 2024-515214-41-00
No phaseTaking people
Iconographic Registry of Pancreatobiliary Endoscopy Procedures
Where
Milan
Age
18 years and over
People
12,000
Run by
IRCCS San Raffaele
See details and how to joinNCT06344507
Phase 1/2Taking people
Phase I/IIa Study: RR001 Administered Following Chemotherapy Cycles for Patients With Locally Advanced Pancreatic Carcinoma
Where
Modena
Age
18 years and over
People
9
Run by
EIR Biotherapies s.r.l.
See details and how to joinNCT06861452 · EU 2024-516019-26-00
No phaseNot yet taking people in Italy
EUS-Based Artificial Intelligence to Predict Outcomes in Pancreatic Cancer
Where
Milan
Age
18 years and over
People
700
Run by
IRCCS San Raffaele
See details and how to joinNCT07803770
Phase 2Not yet taking people in Italy
Immune dynamics and biomarkers of anti-tumor response in BMS-986340 (anti-CCR8) and nivolumab (anti-PD-1) co-treatment of metastatic tumors
Where
Rozzano
Age
18 years and over
People
30
Run by
Humanitas Mirasole S.p.A.
See details and how to join2025-524125-40-01
No phaseNot yet taking people in Italy
Endoscopic Management of Biliopancreatic Disease in the Lombardy Pancreas Units
Where
Bergamo, Brescia, Cremona, Legnano, Mantua, Milan, Monza, Pavia, Varese
Age
18 years and over
People
2,500
Run by
IRCCS San Raffaele
See details and how to joinNCT07418164
No phaseTaking people
Clinical, Oncologic, and Metabolic Effects of Pancreatic Mass Loss After Pancreatectomy in Non-Diabetic Patients
Where
Rome
Age
18 years and over
People
579
Run by
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
See details and how to joinNCT07608055
Phase 2Taking people
LuMIERE: A Phase 1/2, Multicenter, Open label, Non randomized Study to Investigate Safety and Tolerability, Pharmacokinetics, Dosimetry, and Preliminary Activity of [177Lu]Lu-FAP-2286 in Participants with an Advanced Solid Tumor
Where
Meldola, Milan, Naples, Negrar, Reggio Emilia
Age
18 years and over
People
36 worldwide
Run by
Novartis Pharma AG
See details and how to joinNCT04939610 · EU 2023-508995-12-01
Phase 1/2Taking people
A Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors
Where
Candiolo, Milan, Naples, Roma, Rozzano, Siena
Age
18 years and over
People
1,109 worldwide
Run by
Bristol-Myers Squibb
See details and how to joinNCT04895709
Phase 1Taking people
AMG 410 Alone and in Combination With Other Agents in Participants With KRAS Altered Advanced or Metastatic Solid Tumors
Where
Milan, Pisa, Verona
Age
18 years and over
People
434 worldwide
Run by
Amgen
See details and how to joinNCT07094113
Phase 1Taking people
Phase I Study of [177Lu]Lu-NNS309 in Patients With Pancreatic, Lung, Breast and Colorectal Cancers
Where
Milan, Reggio Emilia
Age
18 years to 100 years
People
162 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT06562192
Phase 1Taking people
A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors
Where
Bologna, Milan, Verona
Age
18 years and over
People
714 worldwide
Run by
Seagen, a wholly owned subsidiary of Pfizer
See details and how to joinNCT05208762 · EU 2023-506604-18-00
Phase 1Taking people
A Study to Evaluate INCB161734 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation
Where
Milan, Rozzano, Verona
Age
18 years and over
People
710 worldwide
Run by
Incyte Corporation
See details and how to joinNCT06179160 · EU 2023-507091-47-00