Pancreatic cancer trials in Spain

In Spain 86 Also abroad 1096

86 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 13 November 2026. Ask the study team whether a trial fits you.

Phase 1Taking people
Anti-Ly6E Exatecan ADC M7437 in Advanced Solid Tumors
Where
Barcelona, Madrid
Age
18 years and over
People
138 worldwide
Run by
EMD Serono Research & Development Institute, Inc.
See details and how to joinNCT07360314 · EU 2025-523232-39-00
No phaseEnrolling by invitation
Immunonutrition for Surgical Prehabilitation of Patients With Upper GI Cancer
Where
Madrid
Age
18 years and over
People
110
Run by
Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
See details and how to joinNCT07884214
Phase 1/2Taking people
A Study to Test the Safety and Effectiveness of GSK5764227, Alone or With Other Treatments, in Participants With Advanced Gastrointestinal Cancers That Cannot be Surgically Removed (EMBOLD PanGI-201)
Where
Barcelona, Madrid, Pamplona, Santander, Zaragoza
Age
18 years and over
People
346 worldwide
Run by
GlaxoSmithKline
See details and how to joinNCT06885034
Phase 2/3Not yet taking people in Spain
A Study to Assess Intravenous (IV) Telisotuzumab Adizutecan in Combination with Fluorouracil, Folinic Acid, and Oxaliplatin (FOLFOX) Compared to Standard of Care in Adult Participants with First-Line Metastatic Pancreatic Ductal Adenocarcinoma
Where
Barcelona, Madrid, Zaragoza
Age
18 years and over
People
194 worldwide
Run by
AbbVie Deutschland GmbH & Co. KG
See details and how to join2025-522563-15-00
Phase 1/2Taking people
A Clinical Trial to Test if the Investigational Drug BNT329 is Safe and Potentially Beneficial for People With Advanced Solid Tumors Known to Express the Tumor Marker CA19-9
Where
Barcelona, Logroño, Madrid, Pozuelo de Alarcón
Age
18 years and over
People
245 worldwide
Run by
BioNTech SE
See details and how to joinNCT07186842 · EU 2025-522613-26-00
Phase 1Taking people
KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors
Where
Barcelona, Madrid, Sevilla
Age
18 years and over
People
300 worldwide
Run by
Kura Oncology, Inc.
See details and how to joinNCT06026410 · EU 2024-513285-19-00
Phase 1Taking people
Study to Assess Adverse Events and Change in Disease Activity in Adult Participants With Select Advanced Solid Tumor Indications Receiving Intravenous (IV) ABBV-400
Where
Badalona, Barcelona, Madrid, Málaga, Pamplona, Zaragoza
Age
18 years and over
People
325 worldwide
Run by
AbbVie
See details and how to joinNCT06084481 · EU 2023-506227-29-00
Phase 2/3Taking people
A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue
Where
Barcelona, Madrid, Málaga, Oviedo
Age
18 years and over
People
982 worldwide
Run by
Pfizer
See details and how to joinNCT06989437 · EU 2025-522093-36-00
Phase 1/2Taking people
Study of AZD9574 as Monotherapy and in Combination With Anti-cancer Agents in Participants With Advanced Solid Malignancies
Where
A Coruña, Barcelona, Málaga, Pozuelo de Alarcón, Sant Cugat del Vallès, Sevilla
Age
18 years to 130 years
People
695 worldwide
Run by
AstraZeneca
See details and how to joinNCT05417594 · EU 2023-504984-17-00
Phase 3Taking people
Study of Daraxonrasib and Daraxonrasib + GnP as First-line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma
Where
Barcelona, Córdoba, L'Hospitalet de Llobregat, Madrid, Pamplona, Valencia, Zaragoza
Age
18 years and over
People
900 worldwide
Run by
Revolution Medicines, Inc.
See details and how to joinNCT07491445 · EU 2025-525088-34-00
Phase 2Taking people
AZD0901 in Participants With Advanced Solid Tumours Expressing Claudin18.2
Where
Barcelona, Madrid
Age
18 years and over
People
226 worldwide
Run by
AstraZeneca
See details and how to joinNCT06219941 · EU 2023-508275-37-00
Phase 1Taking people
A Study of PHN-012 in Patients With Advanced Solid Tumors
Where
Barcelona, Madrid, Valencia
Age
18 years and over
People
165 worldwide
Run by
Pheon Therapeutics
See details and how to joinNCT07127874
Phase 1/2Taking people
Phase 1b/2 Study of Anti-CEACAM5 ADC M9140 in Participants With Advanced Pancreatic Cancer (Substudy PDAC)
Where
Badalona, Barcelona, L'Hospitalet de Llobregat, Madrid, Pozuelo de Alarcón
Age
18 years and over
People
26 worldwide
Run by
Merck Healthcare KGaA
See details and how to join2024-517819-74-00
Phase 3Taking people
Phase 3 Study of Investigator Choice of Chemotherapy with or without Zoldonrasib as First-line Treatment in Metastatic KRAS G12D-mutated Pancreatic Adenocarcinoma
Where
Barcelona, Madrid, Málaga, Pamplona, Sevilla
Age
18 years and over
People
281 worldwide
Run by
Revolution Medicines Inc.
See details and how to join2025-524928-21-00
Phase 3Taking people
A Randomized, Double-Blind, Phase 3 Study of Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D–Mutated Metastatic Pancreatic Ductal Adenocarcinoma (DAWN-303)
Where
Badalona, Barcelona, Las Palmas de Gran Canaria, Madrid, Palma, Santander, Sevilla, Valencia, Zaragoza
Age
18 years and over
People
239 worldwide
Run by
Incyte Corp.
See details and how to join2025-525009-18-00
No phaseTaking people
A Pan-European Post-Authorisation Safety Study: Risk of Pancreatic Cancer Among Type 2 Diabetes Patients Who Initiated Exenatide as Compared With Those Who Initiated Other Non-Glucagon-Like Peptide 1 Receptor Agonists Based Glucose Lowering Drugs
Where
Barcelona
Age
18 years to 99 years
People
24,000 worldwide
Run by
AstraZeneca
See details and how to joinNCT05663515
No phaseNot yet taking people in Spain
A Prospective Study of Concurrent Hyperthermia, Chemotherapy and Radiotherapy in Borderline and Locally Advanced Pancreatic Cancer (PANHEAT)
Where
Las Palmas de Gran Canaria, Málaga
Age
18 years to 80 years
People
60
Run by
Fernando Pessoa Canarias University
See details and how to joinNCT07839676
Phase 1/2Taking people
Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors
Where
Barcelona, Madrid, Pamplona, Seville, Valencia, Zaragoza
Age
18 years and over
People
534 worldwide
Run by
Revolution Medicines, Inc.
See details and how to joinNCT06128551
Phase 4Taking people
Efficacy of PERT for PEI in Unresectable Pancreatic Cancer.
Where
Pamplona, Santiago de Compostela
Age
18 years and over
People
100 worldwide
Run by
Hospital Clinico Universitario de Santiago
See details and how to joinNCT06099119
Phase 1/2Taking people
A First-in-Human Trial of BLU-924 (SAR449336) in Advanced Solid Tumors Harboring KRAS Mutations
Where
Barcelona, Madrid, Pamplona, Pozuelo de Alarcón
Age
18 years and over
People
265 worldwide
Run by
Blueprint Medicines Corporation
See details and how to joinNCT07629960
No phaseNot yet taking people in Spain
Personalised Nutritional Care in Older Patients With Pancreatic Ductal Adenocarcinoma
Where
Madrid
Age
65 years and over
People
250 worldwide
Run by
Inna Chen, MD
See details and how to joinNCT07821554
Phase 1Taking people
A phase I open-label, multi-center study to evaluate the safety, tolerability, dosimetry, and preliminary activity of [177Lu]Lu-DFC413 and safety and imaging properties of [68Ga]Ga-NNS309 in patients with solid tumors
Where
Barcelona, L'Hospitalet de Llobregat
Age
18 years and over
People
62 worldwide
Run by
Novartis Pharma AG
See details and how to join2025-521702-18-00
No phaseTaking people
ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation
Where
A Coruña, Barcelona, Girona, Las Palmas de Gran Canaria, Madrid, Málaga, Sabadell, Santiago de Compostela, Valencia
Age
18 years and over
People
2,285 worldwide
Run by
Guardant Health, Inc.
See details and how to joinNCT05059444
Phase 1Taking people
A Study of ASP2138 Given by Itself or Given With Other Cancer Treatments in Adults With Stomach Cancer, Gastroesophageal Junction Cancer, or Pancreatic Cancer
Where
Barcelona, L'Hospitalet de Llobregat, Murcia, Zaragoza
Age
18 years and over
People
398 worldwide
Run by
Astellas Pharma Global Development, Inc.
See details and how to joinNCT05365581 · EU 2023-504514-29-00
Phase 1Taking people
Study to Assess Safety, Tolerability and Activity of DSB2455 in Participants With Advanced Malignancies
Where
Barcelona, Córdoba, Girona, L'Hospitalet de Llobregat, Logrono, Madrid, Málaga, Pamplona, Pozuelo de Alarcón, Sevilla, Valencia
Age
18 years and over
People
180 worldwide
Run by
Duke Street Bio Ltd
See details and how to joinNCT06458712 · EU 2023-508805-26-00