Pancreatic cancer trials in United States

In United States 411 Also abroad 1095

411 trials · From ClinicalTrials.gov, checked 10 November 2026. Ask the study team whether a trial fits you.

Phase 2Taking people
Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic Cancer
Where
Bethesda
Age
18 years to 72 years
People
332
Run by
National Cancer Institute (NCI)
See details and how to joinNCT01174121
Phase 1Taking people
Metarrestin (ML-246) in Subjects With Metastatic Solid Tumors
Where
Bethesda, Fairway
Age
12 years to 120 years
People
116
Run by
National Cancer Institute (NCI)
See details and how to joinNCT04222413
No phaseTaking people
Chemotherapy With or Without IMD10 (Focused Ultrasound) in the Treatment of Borderline Resectable or Locally Advanced Pancreatic Cancer
Where
Boston, Charlottesville, San Antonio
Age
18 years to 85 years
People
366 worldwide
Run by
IMGT Co., Ltd.
See details and how to joinNCT07325214
Phase 2Taking people
At-Home Cancer Directed Therapy Versus in Clinic for the Treatment of Patients With Advanced Cancer
Where
Grand Forks, Jacksonville
Age
18 years and over
People
220
Run by
Mayo Clinic
See details and how to joinNCT05969860
Phase 1Taking people
Radiotherapy in Combination With TTI-101 in Borderline Resectable and Locally Advanced Pancreatic Ductal Adenocarcinoma
Where
Aurora, St Louis
Age
18 years and over
People
24
Run by
Washington University School of Medicine
See details and how to joinNCT06141031
Phase 3Taking people
Lanreotide Versus Placebo Before Surgery to Prevent a Surgical Complication Called a Pancreatic Fistula
Where
Aitkin, Albuquerque, Allentown, Ann Arbor, Ashland, Atlanta, Battle Creek, Baxter, Bethlehem, Birmingham, Brainerd, Burlington, Chadds Ford, Charlotte, Chicago, Cincinnati, Columbus, Concord, Crosslake, Daphne, Deer River, Detroit Lakes, Duarte, Duluth, Easton, Elkton, Ely, Fairhope, Fargo, Farmington, Fosston, Geneva, Gilbert, Grand Rapids, Hayward, Hibbing, Indianapolis, International Falls, Jamestown, Johns Creek, Knoxville, La Jolla, Lexington, Livingston, Loma Linda, Los Angeles, Marshfield, Memphis, Mobile, Moose Lake, Mukwonago, Muskegon, Newark, New Brunswick, New Orleans, Niles, Norton Shores, Oak Brook, Oconomowoc, Omaha, Orland Park, Park Rapids, Pequot Lakes, Pine River, Quakertown, Reed City, Reno, Richmond, Roanoke, Rochester, Ruskin, Sainte Genevieve, Saint Joseph, San Diego, Sandstone, Saraland, Seattle, Sioux Falls, Spooner, Staples, St Louis, Stroudsburg, Sullivan, Sunset Hills, Superior, Syracuse, Tampa, Virginia, Warrenville, Waukesha, Wesley Chapel, West Chester, Wilkes-Barre, Wilmington, Winchester, Wyoming
Age
18 years and over
People
274
Run by
SWOG Cancer Research Network
See details and how to joinNCT06807437
Phase 1Taking people
A Study of ERAS-0015 in Patients With Advanced or Metastatic Solid Tumors
Where
Atlanta, Aurora, Boston, Fairfax, Houston, New York, Santa Rosa, Sarasota, Tampa, Tyler
Age
18 years to 99 years
People
600 worldwide
Run by
Erasca, Inc.
See details and how to joinNCT06983743 · EU 2026-525794-39-00
No phaseTaking people
The Vanguard Study: Testing a New Way to Screen for Cancer
Where
Bethesda, Brownstown, Chapel Hill, Charlottesville, Chesterfield, Cheyenne Wells, Cleveland, Clinton Township, Dearborn, Denver, Detroit, Durham, Fairfax, Fort Collins, Greeley, Grosse Pointe Farms, Honolulu, Kansas City, Lafayette, Livonia, Lone Tree, Loveland, Milwaukee, Minneapolis, Norfolk, Novi, Oklahoma City, Pleasanton, Plymouth, Portsmouth, Richmond, Royal Oak, San Diego, South Hill, Springfield, Sterling Heights, St Louis, Tacoma, Troy, West Bloomfield, Wyandotte
Age
45 years to 75 years
People
24,000
Run by
National Cancer Institute (NCI)
See details and how to joinNCT06995898
No phaseNot yet taking people in United States
Signature Development and Validation Protocol for an Epigenetic Assay in Diagnosing Pancreatic Cancer
Where
Glen Burnie
Age
18 years and over
People
450
Run by
University of Maryland, Baltimore
See details and how to joinNCT07528430
Phase 3Taking people
Atebimetinib + GnP as a First Line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma
Where
Abilene, Arlington Heights, Atlanta, Austin, Belleville, Blacksburg, Chicago, Cincinnati, Columbia, Duarte, East Brunswick, Eugene, Fairfax, Fairway, Fort Collins, Germantown, Greenville, Huntsville, Las Vegas, Lone Tree, Madison, Maumee, Miami, Nashville, Newark, New York, Omaha, Peoria, Philadelphia, Phoenix, Pinehurst, Portland, Port Saint Lucie, San Antonio, San Diego, Sarasota, Seattle, Sioux Falls, St. Petersburg, Vancouver, Webster, West Palm Beach
Age
18 years and over
People
570 worldwide
Run by
Immuneering Corporation
See details and how to joinNCT07562152 · EU 2026-525617-31-00
Phase 3Taking people
Study of Zoldonrasib + Chemo of Investigator's Choice vs Placebo + Chemo of Investigator's Choice as First-line Treatment in Metastatic KRAS G12D-mutated Pancreatic Adenocarcinoma ( RASolute 305 )
Where
Atlanta, Baltimore, Boston, Chicago, Durham, East Brunswick, Gainesville, Houston, Jacksonville, Nashville, New Brunswick, New Haven, New York, Phoenix, Rochester, Tampa, Tucson
Age
18 years and over
People
670 worldwide
Run by
Revolution Medicines, Inc.
See details and how to joinNCT07621718
Phase 2Taking people
A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Pancreatic Cancer
Where
Ann Arbor, Baltimore, Boston, Chapel Hill, Charlottesville, Chicago, Coral Springs, East Brunswick, Fairfax, Fort Worth, Grand Rapids, Houston, Jacksonville, Los Angeles, Madison, Nashville, New York, Rochester, San Antonio, Seattle, St Louis, Tamarac, Tampa, West Valley City
Age
18 years and over
People
185 worldwide
Run by
Verastem, Inc.
See details and how to joinNCT07644559
Phase 3Taking people
Study of Zoldonrasib (RMC-9805) Plus Daraxonrasib (RMC-6236) Versus Gemcitabine and Nab-Paclitaxel as First-Line Treatment in Metastatic KRAS G12D-Mutated Pancreatic Adenocarcinoma
Where
Jacksonville, Phoenix, Providence, Rochester, Scottsdale, Tampa
Age
18 years and over
People
400
Run by
Revolution Medicines, Inc.
See details and how to joinNCT07805954
No phaseTaking people
CREO - Microwave Ablation Feasibility Study
Where
Chicago, Gilbert, Houston, Knoxville, Los Angeles, Morgantown
Age
18 years and over
People
75
Run by
Banner Health
See details and how to joinNCT07817147
Phase 1Taking people
Lm-LLO-TT and Gemcitabine in Unresectable Pancreatic Ductal Adenocarcinoma
Where
The Bronx
Age
18 years and over
People
18
Run by
Loki Therapeutics, Inc.
See details and how to joinNCT07828236
Phase 1Taking people
Modified FOLFIRINOX and Pentamidine in Advanced and Metastatic Pancreatic Cancer
Where
Oklahoma City
Age
18 years and over
People
30
Run by
University of Oklahoma
See details and how to joinNCT07829185
No phaseTaking people
Tissue Procurement and Natural History Study of Patients With Malignant Mesothelioma
Where
Bethesda
Age
2 years to 100 years
People
1,000
Run by
National Cancer Institute (NCI)
See details and how to joinNCT01950572
Phase 2Taking people
APOLLO: A Randomized Phase II Double-Blind Study of Olaparib Versus Placebo Following Curative Intent Therapy in Patients With Resected Pancreatic Cancer and a Pathogenic BRCA1, BRCA2 or PALB2 Mutation
Where
Aberdeen, Adrian, ‘Aiea, Albuquerque, Altamonte Springs, Alton, Ames, Anaconda, Anchorage, Ankeny, Ann Arbor, Appleton, Arroyo Grande, Atlanta, Auburn, Aurora, Ballwin, Bardstown, Basking Ridge, Baton Rouge, Bellevue, Bellingham, Bemidji, Bend, Berkeley, Billings, Bismarck, Bloomington, Boise, Bolivar, Boone, Bozeman, Bridgeport, Brighton, Bryan, Bryn Mawr, Buffalo, Burbank, Burien, Camden, Canton, Cape Girardeau, Carbondale, Carmel, Carroll, Carson City, Carterville, Carthage, Celebration, Centerville, Centralia, Chelsea, Chicago, Cincinnati, Clackamas, Clarkston, Clinton, Clive, Coeur d'Alene, Collegeville, Collierville, Colorado Springs, Columbus, Commack, Coon Rapids, Coos Bay, Coral Gables, Corbin, Council Bluffs, Covington, Creston, Crown Point, Dallas, Danville, Dayton, Dearborn, Decatur, Deerfield Beach, Denver, Des Moines, Detroit, Dixon, Duluth, Durango, Dyer, East China Township, Eau Claire, Edmonds, Effingham, Elmhurst, Enumclaw, Eureka, Everett, ‘Ewa Beach, Exton, Fairbanks, Fairway, Fargo, Farmington, Farmington Hills, Federal Way, Flint, Fort Dodge, Fort Smith, Fort Worth, Franklin, Fremont, Fruitland, Galesburg, Garden City, Gig Harbor, Goldsboro, Grand Island, Great Bend, Great Falls, Green Bay, Greenlawn, Greenville, Grenada, Grosse Pointe Woods, Harrison, Hays, Henderson, Hobart, Honolulu, Hot Springs, Indianapolis, Issaquah, Jacksonville, Janesville, Jefferson, Jefferson City, Johnson Creek, Jonesboro, Joplin, Kalispell, Kansas City, Kearney, Kennewick, Kettering, Kewanee, Kingman, Kissimmee, Lacey, La Crosse, Lake Success, Lakewood, Las Vegas, Lawrence, Lebanon, Lee's Summit, Lexington, Lincoln, Littleton, Livonia, London, Longmont, Longview, Louisville, Macomb, Madison, Marshalltown, Marshfield, Mattoon, Media, Memphis, Meridian, Miami, Middletown, Mineola, Minneapolis, Minocqua, Missoula, Modesto, Monroe, Montvale, Morgantown, Mountain View, Mount Vernon, Mukwonago, Munster, Nampa, Naperville, New Albany, Newberg, New Lenox, New Orleans, New Richmond, New York, North Kansas City, Novi, Oconomowoc, Oconto Falls, O'Fallon, Oklahoma City, Olathe, Omaha, Orange, Oregon City, Orlando, Orland Park, Ottawa, Overland Park, Oxford, Pahrump, Paoli, Papillion, Parker, Parkersburg, Pekin, Peoria, Peru, Philadelphia, Phoenix, Pierre, Pittsburg, Plainfield, Plantation, Pontiac, Portland, Post Falls, Princeton, Pueblo, Puyallup, Redmond, Reno, Renton, Rice Lake, Richardson, Rochester, Rolla, Roseville, Royal Oak, Sacramento, Saginaw, Sainte Genevieve, Saint Johnsbury, Saint Joseph, Saint Louis Park, Saint Paul, Salina, Salt Lake City, Sandpoint, San Francisco, San Luis Obispo, San Mateo, Santa Cruz, Santa Maria, Santa Rosa, Seattle, Sedro-Woolley, Sheboygan, Shelton, Shepherdsville, Silverdale, Sioux Falls, South Bend, Southfield, Southhaven, Spokane, Spokane Valley, Springfield, Sterling Heights, Stevens Point, St Louis, Sturgeon Bay, Sullivan, Sunnyvale, Tacoma, Tawas City, Teaneck, Toledo, Topeka, Troy, Twin Falls, Uniondale, Urbana, Vacaville, Vancouver, Voorhees Township, Walla Walla, Warren, Washington, Washington D.C., Waukee, Waukesha, West Branch, West Des Moines, Weston, Westwood, Williamsville, Winter Park, Wynnewood, Yakima, Yelm, Yorkville, Ypsilanti
Age
18 years and over
People
152 worldwide
Run by
National Cancer Institute (NCI)
See details and how to joinNCT04858334
Phase 2Taking people
Neoadjuvant Folfirinox Combined With Pembrolizumab Followed by Surgery for Patients With Resectable Pancreatic Cancer
Where
Houston
Age
18 years and over
People
39
Run by
Baylor College of Medicine
See details and how to joinNCT05132504
Phase 1Taking people
Anti-Mesothelin TNaive/SCM hYP218 (TNhYP218) CAR T Cells in Participants With Mesothelin-Expressing Solid Tumors Including Mesothelioma
Where
Bethesda
Age
18 years to 120 years
People
120
Run by
National Cancer Institute (NCI)
See details and how to joinNCT06885697
Phase 1Taking people
A Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced Solid Tumors
Where
Boston, Conroe, Duarte, Houston, Irvine, League City, Los Angeles, Nashville, New Haven, Newton, San Antonio, Santa Monica, Sugar Land, Trumbull
Age
18 years and over
People
540 worldwide
Run by
Pfizer
See details and how to joinNCT07090499 · EU 2025-521729-33-00
Phase 1/2Taking people
A 2-part Phase 1/2 Open-label Trial on ODM-212
Where
Fairfax, Fort Worth, Irving, Los Angeles, Orange
Age
18 years and over
People
229 worldwide
Run by
Orion Corporation, Orion Pharma
See details and how to joinNCT07563738
No phaseTaking people
INtegrating Systematic PatIent-Reported Evaluations in Multi-Disciplinary Tumor Boards: The INSPIRE Study
Where
Birmingham, Los Angeles, Oklahoma City
Age
18 years and over
People
2,748
Run by
University of Alabama at Birmingham
See details and how to joinNCT07671937
No phaseNot yet taking people in United States
A Decision Support Tool for Pancreatic Cancer Screening -Aim 2
Where
Chapel Hill
Age
18 years to 99 years
People
40
Run by
UNC Lineberger Comprehensive Cancer Center
See details and how to joinNCT07808671
Phase 1/2Taking people
VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma
Where
Albuquerque, Englewood, Florham Park, Fort Lauderdale, Hartford, Houston, Morristown, New York, Pembroke Pines, Santa Rosa, Washington D.C., York
Age
18 years to 80 years
People
242 worldwide
Run by
VM Oncology, LLC
See details and how to joinNCT03556228